دانلود مقالات ISI درباره FXR، گیرنده Farnesoid X + ترجمه فارسی

یک پپتید آدروفین جدید در بیماریهای قلبی عروقی

A novel peptide adropin in cardiovascular diseases

Keywords: FXR، گیرنده Farnesoid X; DIO, diet-induced obesity; HFD, high-fat diet; CR, calorie restriction; LXR, liver X receptors; FXR, farnesoid X receptor; STZ, streptozotocin; EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid; PUFAs, polyunsaturated fatty acids; MetS, metabolic synd

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

کوئرستین، متابولیسم کلسترول کبدی را با افزایش تجمع اسید کلسترول به صفرا و خروج کلسترول در موش صحرایی

Quercetin regulates hepatic cholesterol metabolism by promoting cholesterol-to-bile acid conversion and cholesterol efflux in rats

Keywords: FXR، گیرنده Farnesoid X; Quercetin; Cholesterol; Bile acids; Lipid metabolism; RatsABCA1, ATP binding cassette transporter A1; ABCG1, ATP binding cassette transporter G1; CYP7A1, cholesterol 7α-hydroxylase; FXR, farnesoid X receptor; HCO, 7α-hydroxy-4-cholesten-3-one; HDL-C, high

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

عملکرد ماکروفاژهای شکل گرفته و ایمنی ذاتی توسط اسیدهای صفراوی: مکانیسم و ​​پیامدهای آن در بیماریهای کبدی کلستاتیک

Shaping macrophages function and innate immunity by bile acids: Mechanisms and implication in cholestatic liver diseases

Keywords: FXR، گیرنده Farnesoid X; BEC, biliary epthelial cells; CA, cholic acid; CBP, CREB-binding protein; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; FXR, farnesoid X receptor; GR, glucocorticoid receptor; ISG, IFN-stimulated gene; PBC, primary biliary cirrhosis; PKI, PKA inhibi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

اثر آنتی بیوتیک های مختلف بر مدولاسیون میکروب بیوتین روده و پروتئین اسید صفرا در موش

Effect of various antibiotics on modulation of intestinal microbiota and bile acid profile in mice

Keywords: FXR، گیرنده Farnesoid X; Abca1, ATP-binding cassette transporter a1; BA, bile acid; CA, cholic acid; Bsep, bile salt-export pump; CDCA, chenodeoxycholic acid; Cyp, cytochrome P450; DCA, deoxycholic acid; Fxr, farnesoid X receptor; GAPDH, glyceraldehyde 3-phosphate dehydrogenase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

استاتو هپاتیت غیر آلرژی به عنوان یک بازیکن جدید در اختلال نعوظ ناشی از سندرم متابولیک: یک مطالعه تجربی در خرگوش

Nonalcoholic steatohepatitis as a novel player in metabolic syndrome-induced erectile dysfunction: An experimental study in the rabbit

Keywords: FXR، گیرنده Farnesoid X; ED, erectile dysfunction; MetS, metabolic syndrome; NASH, nonalcoholic steatohepatitis; CVD, cardiovascular disease; T, testosterone; FXR, farnesoid X receptor; OCA, obeticholic acid; RD, regular diet; Ach, acetylcholine; T2DM, type 2 diabetes mellitus; N

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

اضافه کردن دگزامتازون باعث ایجاد ترکیب اسید صفراوی با القاء CYP8B1 در کشت های اولیه هپاتوسیت های انسانی می شود

Addition of Dexamethasone Alters the Bile Acid Composition by Inducing CYP8B1 in Primary Cultures of Human Hepatocytes

Keywords: FXR، گیرنده Farnesoid X; BSEP, bile salt export pump; CA, cholic acid; CDCA, chenodeoxycholic acid; CYP7A1, cholesterol 7α-hydroxylase; CYP8B1, sterol 12α-hydroxylase; CYP27A1, sterol 27α-hydroxylase; FXR, farnesoid X receptor; G6Pase, glucose-6-phosphatase; GR, glucocorticoid re

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Determination of 7α-OH cholesterol by LC–MS/MS: Application in assessing the activity of CYP7A1 in cholestatic minipigs

Keywords: FXR، گیرنده Farnesoid X; FXR, Farnesoid X receptor; CDCA, Chenodeoxycholic acid; OCA, Obeticholic acid; TPN, Total Parenteral Nutrition; DTT, dithiothreitol; PMSF, phenylmethanesulfonyl fluorideLC–MS/MS; CYP7A1; Cholesterol 7α-hydroxylase activity; 7α-OH cholesterol; Liver micros

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

MDG-1, an Ophiopogon polysaccharide, alleviates hyperlipidemia in mice based on metabolic profile of bile acids

Keywords: FXR، گیرنده Farnesoid X; FXR, farnesoid X receptor; LXR, liver X receptor; NAFLD, nonalcoholic fatty liver disease; FOS, fructooligosaccharides; DIO, diet-induce obese; UPLC–MS, ultra-performance liquid chromatography mass-spectrometry; CA, cholic acid; CDCA, chenodeoxycholic aci

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Novel FXR (farnesoid X receptor) modulators: Potential therapies for cholesterol gallstone disease

Keywords: FXR، گیرنده Farnesoid X; FXR, farnesoid X receptor; CDCA, chenodeoxycholic acid; UDCA, ursodeoxycholic acid; 6EUDCA, 6-αethyl-ursodeoxycholic acid; qPCR, quantitative polymerase chain reaction; TGR5, G-protein-coupled receptor

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Enterocyte fatty acid-binding proteins (FABPs): Different functions of liver and intestinal FABPs in the intestine

Keywords: FXR، گیرنده Farnesoid X; Fatty acid-binding protein; Fatty acid; Intestine; Lipid; LFABP; IFABP2-AG, 2-arachidonoylglycerol; AEA, arachidinoylethanolamide; CB1, cannabinoid receptor 1; CB2, cannabinoid receptor 2; FA, fatty acid; FXR, farnesoid X receptor; IFABP, intestinal fatty

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Fibrates and fish oil, but not corn oil, up-regulate the expression of the cholesteryl ester transfer protein (CETP) gene

Keywords: FXR، گیرنده Farnesoid X; apoB, apolipoprotein B; BEZA, bezafibrate; CVD, cardiovascular disease; CHOL, cholesterol; CETP, cholesteryl ester transfer protein; CE, cholesteryl esters; CO, corn oil; FXR, farnesoid X receptor; FENO, fenofibrate; FO, fish oil; GEM, gemfibrozil; LP, li

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

5β-Reduced steroids and human Δ4-3-ketosteroid 5β-reductase (AKR1D1)

Keywords: FXR، گیرنده Farnesoid X; AKR, aldo–keto reductase; AKR1C1–AKR1C4, human hydroxysteroid dehydrogenase; AKR1D1, human steroid 5β-reductase; AKR1D2, rat steroid 5β-reductase; CAR, constitutive androstane receptor; ERK, extracellular-signal regulated kinase; FXR, farnesoid X receptor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Anthranilic acid derivatives as novel ligands for farnesoid X receptor (FXR)

Keywords: FXR، گیرنده Farnesoid X; SAR, structure–activity-relationship; FXR, farnesoid X receptor; RXR, retinoid X receptor; DMEM, Dulbecco’s modified eagle medium; FCS, fetal calf serum; DMSO, dimethyl sulfoxide; NAFLD, non-alcoholic fatty liver disease; PBC, primary biliary cirrhosis; P

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of trisubstituted-pyrazol carboxamide analogs as novel and potent antagonists of farnesoid X receptor

Keywords: FXR، گیرنده Farnesoid X; HTS, high-throughput screen; FXR, farnesoid X receptor; NRs, nuclear receptors; Cyp7A1, cytochrome 7A1; BAs, bile acids; BSEP, bile salt export pump; SAR, structure–activity relationship; LBD, ligand-binding domain

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

Ethanol potentiates hepatitis B virus replication through oxidative stress-dependent and -independent transcriptional activation

Keywords: FXR، گیرنده Farnesoid X; ADH, acetaldehyde; cccDNA, covalently closed circular DNA; CHB, chronic hepatitis B; CYP2E1, cytochrome p450 2E1; DCFDA, dichlorofluoresceindiacetate; FBS, fetal bovine serum; FXR, farnesoid X receptor; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GSH

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Genetics of biliary lithiasis from an ethnic perspective

Keywords: FXR، گیرنده Farnesoid X; ABCG5/8, Hepatobiliary cholesterol transporter; ApoB100, Apolipoprotein B100; ApoE4, Apolipoprotein E4; CI, Confidence interval; CYP7A1, Cholesterol 7-alpha hydroxylase; FOXO1, Forkhead box O1; FXR, Farnesoid X receptor; GSD, Gallstone disease; GWAS, Geno

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of N-Myc downstream regulated gene 2 by bile acids

Keywords: FXR، گیرنده Farnesoid X; CDCA, chenodeoxycholic acid; EMSA, electrophoretic mobility shift assay; ENaC, epithelial sodium channel; FXR, farnesoid X receptor; HCC, hepatocellular carcinoma; I-BABP, ileal-bile acid-binding protein; IR1, inverted repeat separated by a nucleotide; MO

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The alpha-glucosidase inhibitor miglitol affects bile acid metabolism and ameliorates obesity and insulin resistance in diabetic mice

Keywords: FXR، گیرنده Farnesoid X; α-GI, Alpha-glucosidase inhibitors; D2, type 2 iodothyronine deiodinase; FXR, farnesoid X receptor; G-6-Pase, glucose 6-phosphatase; GLP-1, glucagon-like peptide-1; MCP-1, monocyte chemotactic protein-1; PAI-1, plasminogen activator inhibitor-1; TNF-α, tu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Metabolic adaptation allows Amacr-deficient mice to remain symptom-free despite low levels of mature bile acids

Keywords: FXR، گیرنده Farnesoid X; Amacr, α-methylacyl-CoA racemase; FXR, farnesoid X receptor; IBAT, ileal bile acid transporter (known also as the sodium-dependent bile acid transporter ASBT); LXR, liver X receptor; PPAR, peroxisome proliferator-activated receptor; CDCA, chenodeoxycholic

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Organic anion-transporting polypeptide 1a4 (Oatp1a4) is important for secondary bile acid metabolism

Keywords: FXR، گیرنده Farnesoid X; Abca1, ATP-binding cassette transporter a1; BA, bile acid; CA, cholic acid; Bsep, bile salt-export pump; CDCA, chenodeoxycholic acid; Cyp, cytochrome P450; DCA, deoxycholic acid; Fxr, farnesoid X receptor; Gapdh, glyceraldehyde 3-phosphate dehydrogenase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Nuclear receptors, bile acids and cholesterol homeostasis series – Bile acids and pregnancy

Keywords: FXR، گیرنده Farnesoid X; BSEP, bile salt export pump; CA, cholic acid; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; FXR, farnesoid X receptor; ICP, intrahepatic cholestasis of pregnancy; LCA, lithocholic acid; NTCP, Na+-taurocholate cotransporting polypeptide; UDCA, ursode

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Sesquiterpene action, and morphogenetic signaling through the ortholog of retinoid X receptor, in higher Diptera

Keywords: FXR، گیرنده Farnesoid X; RXR, retinoid X receptor; EcR, ecdysone receptor; USP, ultraspiracle; FXR, farnesoid X receptor; LXR, liver X receptor; JH, juvenile hormone; Met, Methoprene tolerant; 20E, 20-hydroxy ecdysone; PTG, prothoracic gland; MDCF, methyl dichlorofarnesoate; MCFs

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Resveratrol inhibits LXRα-dependent hepatic lipogenesis through novel antioxidant Sestrin2 gene induction

Keywords: FXR، گیرنده Farnesoid X; ACC, Acetyl-CoA carboxylase; AMPK, AMP-activated protein kinase; DN-AMPK, Dominant-negative AMP-activated protein kinase; FAS, Fatty acid synthase; FXR, Farnesoid X receptor; GSH, glutathione; HFD, High-fat diet; LXRα, Liver X receptor-α; LXRE, Liver X re

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

α-Methylacyl-CoA racemase (AMACR): Metabolic enzyme, drug metabolizer and cancer marker P504S

Keywords: FXR، گیرنده Farnesoid X; AMACR, α-methylacyl-CoA racemase (also known as P504S); 2-APA, 2-arylpropanoic acid (‘profen’); CAR, constitutive androstane receptor; CoA, coenzyme A; FXR, farnesoid X receptor; MCR, AMACR homolog from M. tuberculosis; NMR, nuclear magnetic resonance; NR

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Epigenomic regulation of bile acid metabolism: Emerging role of transcriptional cofactors

Keywords: FXR، گیرنده Farnesoid X; FXR, farnesoid X Receptor; PTM, post-translational modification; NR, nuclear receptor; DBD, DNA binding domain; LBD, ligand binding domain; GPCR, G-protein coupled receptor; GLP-1, glucagon-like peptide 1; ChIP, chromatin immunoprecipitation; Cyp7a1, chol

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling

Keywords: FXR، گیرنده Farnesoid X; PC, pancreatic cancer; MUC4, mucin4; GS, Guggulsterone; STAT, signal transduction and activator of transcription; FXR, Farnesoid X receptor; EMT, epithelial to mechenchymal transition; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; HNS

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Novel stereoselective synthesis and chromatographic evaluation of E-guggulsterone

Keywords: FXR، گیرنده Farnesoid X; Guggulsterone; Stereoselective synthesis; HPLC; FXRGS, guggulsterone; FXR, farnesoid X receptor

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Involvement of multiple elements in FXR-mediated transcriptional activation of FGF19

Keywords: FXR، گیرنده Farnesoid X; CA, cholic acid; ChIP, chromatin immunoprecipitation; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; EMSA, electrophoretic mobility shift assay; FGF19, fibroblast growth factor 19; FXR, farnesoid X receptor; LCA, lithocholic acid; PCR, polymerase cha

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Perspective: TGR5 (Gpbar-1) in liver physiology and disease

Keywords: FXR، گیرنده Farnesoid X; CA, cholic acid; cAMP, cyclic AMP; CBDL, common bile duct ligation; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; eNOS, endothelial nitric oxide synthase; FXR, farnesoid X receptor; GLP-1, glucagon-like peptide-1; HSC, hepatic stellate cells; INT-77

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Primary biliary cirrhosis and bile acids

Keywords: FXR، گیرنده Farnesoid X; FXR, Farnesoid X receptor; PBC, Primary biliary cirrhosis; PPARα, peroxisome proliferator-activated receptor alpha; PXR, Pregnane X receptor; UDCA, ursodeoxycholic acid

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

MicroRNA-421 functions as an oncogenic miRNA in biliary tract cancer through down-regulating farnesoid X receptor expression

Keywords: FXR، گیرنده Farnesoid X; miR-421, microRNA-421; FXR, farnesoid X receptor; BTC, biliary tract cancer; CCA, cholangiocarcinoma; GBC, gallbladder cancer; ICC, intrahepatic cholangiocarcinoma; ECC, extrahepatic cholangiocarcinoma; PCC, perihilar cholangiocarcinoma; DECC, distal extr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Synergistic growth inhibition of human hepatocellular carcinoma cells by acyclic retinoid and GW4064, a farnesoid X receptor ligand

Keywords: FXR، گیرنده Farnesoid X; ACR, acyclic retinoid; CI, combination index; DAPI, 4’,6-diamidino-2-phenylindole; ERK, extracellular signal-regulated kinase; FXR, farnesoid X receptor; FXRE, farnesoid X receptor response element; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; HCC, he

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Maternal low-protein diet causes epigenetic deregulation of HMGCR and CYP7α1 in the liver of weaning piglets

Keywords: FXR، گیرنده Farnesoid X; CP, crude protein; CYP7α1, cholesterol-7alpha-hydroxylase; FXR, farnesoid X receptor; H3ac, histone H3 acetylation; H3K9me1, histone H3 lysine 9 monomethylation; H3K4me3, histone H3 lysine 4 trimethylation; H3K27me3, histone H3 lysine 27 trimethylation; H

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Fish oil — How does it reduce plasma triglycerides?

Keywords: FXR، گیرنده Farnesoid X; 4-HDoHE, 4-hydroxydocosahexaenoic acid; ATM, adipose tissue macrophages; CoA, coenzyme A; COX, cyclooxygenase; CYP, cytochrome P450; DGAT, diacylglycerol acyltransferase; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; FXR, farnesoid X receptor; FA

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Activation of liver X receptor attenuates endothelin-1 expression in vascular endothelial cells

Keywords: FXR، گیرنده Farnesoid X; ET-1, endothelin-1; VECs, vascular endothelial cells; LPS, lipopolysaccharide; NF-κb, nuclear factor-κB; FXR, farnesoid X receptor; PPARα, peroxisome proliferator-activated receptors α; PPARγ, peroxisome proliferator-activated receptors γ; LXR, liver X re

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Up-regulation of FXR isoforms is not required for stimulation of the expression of genes involved in the lack of response of colon cancer to chemotherapy

Keywords: FXR، گیرنده Farnesoid X; CDDP, cis-diamminedichloroplatinum(II); CRAC, colorectal adenocarcinoma; 5-FU, 5-fluorouracil; FXR, farnesoid X receptor; MDR, multidrug resistance; MOC, mechanism of chemoresistance; TKI, tyrosine kinase inhibitor; TLDA, Taqman Low-Density ArrayChemoresi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

FXR and PXR: Potential therapeutic targets in cholestasis

Keywords: FXR، گیرنده Farnesoid X; BDL, bile duct ligation; CA, cholic acid; CDCA, chenodeoxycholic acid; DCA, deoxycholic acid; FXR, Farnesoid X Receptor; LCA, lithocholic acid; LXR, liver X receptor; NR, nuclear receptor; PBC, primary biliary cirrhosis; PCN, pregnenolone 16α-carbonitrile

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Proteomics for the discovery of nuclear bile acid receptor FXR targets

Keywords: FXR، گیرنده Farnesoid X; NR, nuclear receptor; FXR, farnesoid X receptor; BA, bile acid; FXR−/−, FXR loss-of-functionNuclear receptor; FXR; Proteomic analysis; Expression profiling; Post-transcriptional modification; Mitochondrial

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Activation of bile salt nuclear receptor FXR is repressed by pro-inflammatory cytokines activating NF-κB signaling in the intestine

Keywords: FXR، گیرنده Farnesoid X; BDL, bile duct ligation; CD, Crohn disease; DSS, dextran sodium sulfate; EV, empty vector; FGF, fibroblast growth factor; FXR, farnesoid X receptor; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; GST, glutathione S-transferase; IBABP, intestinal bile ac

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Regulation of FXR transcriptional activity in health and disease: Emerging roles of FXR cofactors and post-translational modifications

Keywords: FXR، گیرنده Farnesoid X; FXR, Farnesoid X Receptor; PTM, post-translational modification; NR, nuclear receptors; AF-1, activation function 1; AF-2, activation function 2; DBD, DNA binding domain; LBD, ligand binding domain; CDCA, chenodeoxycholic acid; FXRE, FXR response element;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Hepatic expression of cytochrome P450s in hepatocyte nuclear factor 1-alpha (HNF1α)-deficient mice

Keywords: FXR، گیرنده Farnesoid X; HNF, hepatocyte nuclear factor; CYP, cytochrome P450; MODY-3, maturity onset diabetes of the young type 3; NIDDM, non-insulin-dependent diabetes mellitus; CAR, constitutive active receptor; PXR, pregnane X receptor; FXR, farnesoid X receptor; c/EBPα and β

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

High expression of liver histone deacetylase 3 contributes to high-fat-diet-induced metabolic syndrome by suppressing the PPAR-γ and LXR-α-pathways in E3 rats

Keywords: FXR، گیرنده Farnesoid X; ALT, alanine transaminase; C/EBPs, CCAATT/enhancer binding proteins; CYP7A1, cholesterol 7α-hydroxylase; FXR, farnesoid X receptor; FAS, fatty acid synthase; G-6-Pase, glucose-6-phosphatase; GLUT, glucose transporter; GPT, glutamate-pyruvate transaminase;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Upregulation of early growth response factor-1 by bile acids requires mitogen-activated protein kinase signaling

Keywords: FXR، گیرنده Farnesoid X; Egr-1, early growth response factor-1; DCA, deoxycholic acid; CDCA, chenodeoxycholic acid; MAPK, mitogen-activated protein kinases; FXR, farnesoid X receptor; Erk, extracellular signal-regulated kinase; BDL, bile duct ligationEarly growth response factor-

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Regulation of CYP3A4 by pregnane X receptor: The role of nuclear receptors competing for response element binding

Keywords: FXR، گیرنده Farnesoid X; CAR, constitutive androstane receptor; COUP-TF, chicken ovalbumin upstream promoter transcription factor; CYP, cytochrome P450; DMSO, dimethyl sulfoxide; DR, direct repeat; ER, everted repeat; FXR, farnesoid X receptor; IR, inverted repeat; kb, kilobase p

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Werner's syndrome helicase participates in transcription of phenobarbital-inducible CYP2B genes in rat and mouse liver

Keywords: FXR، گیرنده Farnesoid X; Ab, antibody; CAR, constitutive androstane receptor; C/EBPα, CCAAT/enhancer binding protein α; ChIP, chromatin immunoprecipitation; EMSA, electrophoresis mobility shift assay; FXR, farnesoid X receptor; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HPR

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

The effect of high-amylose cornstarch on lipid metabolism in OVX rats is affected by fructose feeding

Keywords: FXR، گیرنده Farnesoid X; ACAT-1, acyl-coenzyme A:cholesterol acyltransferase 1; ACAT-2, acyl-coenzyme A:cholesterol acyltransferase 2; ApoB, apolipoprotein B; CYP7A1, cholesterol 7α-hydroxylase; CYP8B1, cholesterol 12α-hydroxylase; DF, dietary fiber; FXR, farnesoid X receptor; HD

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Phosphorylation of sterol regulatory element-binding protein (SREBP)-1a links growth hormone action to lipid metabolism in hepatocytes

Keywords: FXR، گیرنده Farnesoid X; ABCA1, ATP-binding cassette transporter 1; ACC, acetyl coenzyme A carboxylase; CD36, scavenger receptor; Erk-MAPK, extracellular regulated mitogen activated protein kinase; FAS, fatty acid synthase; FXR, farnesoid X receptor; GH, growth hormone; HDL, high

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Quantification of the 15 major human bile acids and their precursor 7α-hydroxy-4-cholesten-3-one in serum by liquid chromatography–tandem mass spectrometry

Keywords: FXR، گیرنده Farnesoid X; C4, 7α-hydroxy-4-cholesten-3-one; CA, cholic acid; CDCA, chenodeoxycholic acid; CYP7A1, cholesterol 7α-hydroxylase; DCA, deoxycholic acid; ESI, electrospray ionisation; FDA, Food and Drug Administration; FXR, farnesoid X receptor; GCA, glycocholic acid; G

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Rapid quantification of bile acids and their conjugates in serum by liquid chromatography–tandem mass spectrometry

Keywords: FXR، گیرنده Farnesoid X; BA, bile acid; CA, cholic acid; CDCA, chenodeoxycholic acid; CV, coefficient of variation; DCA, deoxycholic acid; ESI-MS/MS, electrospray ionization tandem mass spectrometry; FDA, US food and drug administration; FXR, farnesoid X receptor; GC, gas chromat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Bile Salts Control the Antimicrobial Peptide Cathelicidin Through Nuclear Receptors in the Human Biliary Epithelium

Keywords: FXR، گیرنده Farnesoid X; CDCA, chenodeoxycholic acid; ERK, extracellular regulated kinase; FXR, farnesoid X receptor; hBD-2, human β 2 defensins; PBC, primary biliary cirrhosis; PCR, polymerase chain reaction; VDR, vitamin D nuclear receptor; VDRE, VDR response element

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه