Keywords: G-پروتئین همراه گیرنده; G-protein coupled receptor; Vertebrate innovation; Genome duplication; Conserved synteny; Ohnologs; Neural crest
مقالات ISI G-پروتئین همراه گیرنده (ترجمه نشده)
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Keywords: G-پروتئین همراه گیرنده; ACC; Acetyl CoA carboxylase; ATP; adenosine triphosphate; ATGL; adipose triglyceride lipase; AMPK; AMP-activated protein kinase; Ang I; angiotensin I; Ang II; angiotensin II; ACE; angiotensin converting enzyme; ACE2; angiotensin converting enzyme 2; AT1R;
Keywords: G-پروتئین همراه گیرنده; GH; growth hormone; GHRL; ghrelin; GHS-R; growth hormone secretagogue receptor; GOAT; ghrelin O-acyl transferase; GPCR; G-protein coupled receptor; MBOAT; membrane-bound O-acyl transferase; Cds; coding sequences; Ghrelin; GOAT; GHS-R 1a; Monotremes; Evolu
Keywords: G-پروتئین همراه گیرنده; ABC; ATP-binding cassette; ADH; alcohol dehydrogenase; ADR; adrenodoxin reductase; ADX; adrenodoxin; ARE2; sterol acyltransferase; ARV1; mediator of sterol homeostasis; BTS1; GGPP synthase; CPR; cytochrome P450 reductase; CRT; carotenogenic (genes); CYP;
Keywords: G-پروتئین همراه گیرنده; ARC; arachidonate-regulated Ca2+ entry channels; BBB; blood-brain barrier; BCEC; bovine brain capillary endothelial cells; BK; bradykinin; CaM; calmodulin; CaMKII; Ca2+/calmodulin-dependent kinase II; cGMP; cyclic guanosine monophosphate; CRAC; Ca2+ rel
Spiro[pyrrolidine-3,3â²-oxindoles] as 5-HT7 receptor ligands
Keywords: G-پروتئین همراه گیرنده; Oxindole; 5-HT7R; G-protein coupled receptor; Oxidative spiro-rearrangement; Pharmacophore model;
G-protein coupled receptors (GPCR) and environmental exposure. Consequences for cell metabolism using the β-adrenoceptors as example
Keywords: G-پروتئین همراه گیرنده; G-protein coupled receptor; GPCR; Endocrine disruptor; Environmental contaminant; Polycyclic aromatic hydrocarbon; Adrenoreceptor; Adrenergic receptor; Beta-adrenergic receptor; Inflammation; Non-communicable disease; PAH; Energetic metabolism;
Tauroursodeoxycholic acid binds to the G-protein site on light activated rhodopsin
Keywords: G-پروتئین همراه گیرنده; Bile acid; Chemical biology; G protein; G proteinâcoupled receptor (GPCR); Molecular docking; Photoreceptor; Phototransduction; Retina; Rhodopsin; Signal transduction; GPCR; G-protein coupled receptor; G-protein; heterotrimeric GTP-binding protein; R; d
Gender-specific desensitization of group I metabotropic glutamate receptors after maternal l-glutamate intake during lactation
Keywords: G-پروتئین همراه گیرنده; l-Glu; l-glutamate; mGluR; metabotropic glutamate receptor; CNS; Central Nervous System; GPCR; G-protein coupled receptor; PLC; phospholipase C; A.U.; arbitrary units; Group I-metabotropic glutamate receptor; Lactation; l-glutamate; Neonatal brain;
Mechanical stretch increases L-type calcium channel stability in cardiomyocytes through a polycystin-1/AKT-dependent mechanism
Keywords: G-پروتئین همراه گیرنده; Heart; Neonatal rat ventricular myocytes; Cav1.2; Cavβ; G-protein coupled receptor;
The role of the ShcD and RET interaction in neuroblastoma survival and migration
Keywords: G-پروتئین همراه گیرنده; Akt,; Protein kinase B;; ALK,; Anaplastic Lymphoma Kinase; CMV,; Cytomegalovirus; DMEM,; Dulbecoo Modified Eagle's Medium;; DNA,; Deoxyribonucleic Acid; ECL,; Enhanced Chemiluminescence;; EGF,; Epidermal Growth Factor;; EGFR,; Epidermal Growth Factor Rece
An incretin-based tri-agonist promotes superior insulin secretion from murine pancreatic islets via PLC activation
Keywords: G-پروتئین همراه گیرنده; Tri-agonist; Signaling cascade; Pancreatic islets; Insulin secretion; G proteins; TRP channels; AC; Adenylyl cyclase; cAMP; Cyclic adenosine monophosphate; ECL; Extracellular loop; EPAC; Exchange protein directly activated by cAMP; FCS; Fetal calf serum;
The tamoxifen derivative ridaifen-B is a high affinity selective CB2 receptor inverse agonist exhibiting anti-inflammatory and anti-osteoclastogenic effects
Keywords: G-پروتئین همراه گیرنده; Cannabinoid receptors; G-protein coupled receptors; Inverse agonist; Antagonist; Drug action; AC; adenylyl cyclase; CB1R; cannabinoid receptor type 1; CB2R; cannabinoid receptor type 2; CHO; Chinese hamster ovary; CP-55,940; 5-(1,1-dimethylheptyl)-2-[5-hy
Inhibition of cytokine-mediated JNK signalling by purinergic P2Y11 receptors, a novel protective mechanism in endothelial cells
Keywords: G-پروتئین همراه گیرنده; G-protein coupled receptors; Interleukin-1β; C-Jun N-terminal kinase; Purinergic receptors; Inflammation; YM-254890 (PubChem CID: 9919454); H-89 (PubChem CID: 449241); NF340 (PubChem CID: 73755007); MRS2179 (PubChem CID: 24867852); ZM241385 (PubChem CID:
Biased G protein-coupled receptor agonism mediates Neu1 sialidase and matrix metalloproteinase-9 crosstalk to induce transactivation of insulin receptor signaling
Keywords: G-پروتئین همراه گیرنده; GPCR; G-protein coupled receptor; 4MUNANA or 4-MU; 2â²-(4-methylumbelliferyl)-α-D-N-acetylneuraminic acid; OP; oseltamivir phosphate; MMP; matrix metalloproteinase; NMBR; neuromedin B receptor; BR2; bradykinin receptor; AT2R or AngIIR1; angiotensin II r
Optimization of the first small-molecule relaxin/insulin-like family peptide receptor (RXFP1) agonists: Activation results in an antifibrotic gene expression profile
Keywords: G-پروتئین همراه گیرنده; Relaxin; G-protein coupled receptor; Antifibrotic; 2-Acetamido-N-Phenylbenzamide;
Similarities and differences between the responses induced in human phagocytes through activation of the medium chain fatty acid receptor GPR84 and the short chain fatty acid receptor FFA2R
Keywords: G-پروتئین همراه گیرنده; APC; allophycocyaninin; AU; arbitrary units; BSA; bovine serum albumin; C5aR; complement fragment 5a receptor; CI; confidence interval; Cmp1; Compound 1; CTAB; Hexadecyltrimethylammonium bromide; DMSO; dimethyl sulfoxide; FCS; fetal calf serum; FFAs; free
Î9-Tetrahydrocannabinol changes the brain lipidome and transcriptome differentially in the adolescent and the adult
Keywords: G-پروتئین همراه گیرنده; 2-AG; 2-arachidonoyl glycerol; AA; arachidonic acid; AEA; N-arachidonoyl ethanolamine; A-Taur; N-arachidonoyl taurine; Cdkn1a; cyclin dependent kinase inhibitor 1A; CER; cerebellum specific for this study; cldn5; claudin 5; CTX; cortex specific for this s
Novel indanone derivatives as MAO B/H3R dual-targeting ligands for treatment of Parkinson's disease
Keywords: G-پروتئین همراه گیرنده; Multi-targeting; Neurodegenerative diseases; Histamine H3 receptor antagonist; Monoamine oxidase inhibitor; Neurotransmitter dysregulation; Parkinson's disease; AChE; acetylcholinesterase; anal. calc.; elementary analysis calculated; BuChE; butyrylcholine
Activation of imidazoline receptor I2, and improved pancreatic β-cell function in human islets
Keywords: G-پروتئین همراه گیرنده; G-protein coupled receptor; Signal; Second messenger; Cell function;
Elevenin regulates the body color through a G protein-coupled receptor NlA42 in the brown planthopper Nilaparvata lugens
Keywords: G-پروتئین همراه گیرنده; Neuropeptide; G-protein coupled receptor; RNA interference; Insect hemiptera;
Compartmentalized crosstalk of CFTR and TMEM16A (ANO1) through EPAC1 and ADCY1
Keywords: G-پروتئین همراه گیرنده; ADCY1; adenylate cyclase type 1; ANO1; anoctamin 1; BFA; brefeldin A; CCH; carbachol; CFTR; cystic fibrosis transmembrane conductance regulator; EPAC1; exchange protein directly activated by cAMP; ER; endoplasmic reticulum; GPCR; G-protein coupled recepto
Differential roles of PKC isoforms (PKCs) in GnRH stimulation of MAPK phosphorylation in gonadotrope derived cells
Keywords: G-پروتئین همراه گیرنده; GnRH; PKCα; PKCβII; PKCδ; PKCε; MAPK; ERK; JNK; p38; Gonadotropes; LβT2 cells; αT3-1 cells; anti-DP antibodies; anti-diphospho-antibodies; DAG; diacylglycerol; DN; dominant negative; ERK; extracellular signal-regulated kinase; FSH; follicle stimula
Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets
Keywords: G-پروتئین همراه گیرنده; Platelet inhibition; Phosphoproteome; cGMP-dependent protein kinase/PKG; Small GTP-binding proteins; G proteins; NO; nitric oxide; PKA; protein kinase A; PKG; protein kinase G; PDE; phosphodiesterase; sGC; soluble guanylate cyclase; GPCR; G-protein couple
“Force-from-lipids” gating of mechanosensitive channels modulated by PUFAs
Keywords: G-پروتئین همراه گیرنده; MscS; Mechanosensitive channel of Small conductance; MscL; Mechanosensitive channel of Large conductance; TRPC1; Transient Receptor Potential Channel 1; GPCR; G-Protein Coupled Receptor; NMR; Nuclear Magnetic Resonance; WT; Wild-Type; PUFA; Poly-Unsaturat
F2-isoprostanes affect macrophage migration and CSF-1 signalling
Keywords: G-پروتئین همراه گیرنده; Akt; Protein Kinase B; BMM; Bone Marrow derived Macrophages; BSA; Bovine Serum Albumin; Chol-IsoP; Cholesterol-Isoprostane; CSF-1; Colony Stimulating Factor-1; CSF-1R; Colony Stimulating Factor-1 Receptor; DAPI 4â²; 6-Diamidino-2-phenylindole; DMSO; Dime
Photoreceptor calcium sensor proteins in detergent-resistant membrane rafts are regulated via binding to caveolin-1
Keywords: G-پروتئین همراه گیرنده; Cav1-101; N-terminal fragment of bovine caveolin-1; Cav81-101; peptide corresponding to scaffold domain of bovine caveolin-1; CNS; central nervous system; CAC; critical aggregation concentration; DRM; detergent-resistant membrane; EF1-EF4; EF-hand Ca2
αCGRP, another amyloidogenic member of the CGRP family
Keywords: G-پروتئین همراه گیرنده; CGRP; Calcitonin Gene Related Peptide; CT; calcitonin; IAPP; islet amyloid polypeptide; GPCR; G-Protein Coupled Receptor; RAMP; Receptor Activity Modifying Protein; T2D; Type 2 Diabetes; MTC; Medullary Thyroid Carcinoma; MD; Molecular Dynamics; CD; Circul
Benzo(a)pyrene attenuates the pattern-recognition-receptor induced proinflammatory phenotype of murine macrophages by inducing IL-10 expression in an aryl hydrocarbon receptor-dependent manner
Keywords: G-پروتئین همراه گیرنده; Ab; antibody; AhR; aryl hydrocarbon receptor; APC; antigen-presenting cell; ARNT; AhR nuclear translocator; BaP; benzo(a)pyrene; BMDCs; bone-marrow derived dendritic cells; BMMs; bone-marrow derived macrophages; CD; cluster of differentiation; CYP 450; cy
Comparative hepatic transcriptome analyses revealed possible pathogenic mechanisms of fasiglifam (TAK-875)-induced acute liver injury in mice
Keywords: G-پروتئین همراه گیرنده; Fasiglifam (TAK-875); Drug-induced liver injury (DILI); Microarray; Comparative hepatic transcriptome analysis; Gene set enrichment analysis; ALT; Alanine aminotransferase; Bsep; Bile salt export pump; CCl4; Carbon tetrachloride; ConA; Concanavalin A; DAM
N-Thiazolylamide-based free fatty-acid 2 receptor agonists: Discovery, lead optimization and demonstration of off-target effect in a diabetes model
Keywords: G-پروتئین همراه گیرنده; AUCu; unbound area-under-the-curve; (S)-BINAP; (S)-(-)-(1,1â²-binaphthalene-2,2â²-diyl)bis(diphenylphosphine); CLu; unbound systemic clearance rate; Compd; compound; DIEA; N,N-diisopropyl ethylamine, EtOAc, ethyl acetate; FFA2 receptor; free fatty acid-
Snake venom components in medicine: From the symbolic rod of Asclepius to tangible medical research and application
Keywords: G-پروتئین همراه گیرنده; ACE; angiotensin-converting enzyme; ADAM; A disintegrin a metalloproteinase; BM; basal membrane; BPP; bradykinin-potentiating peptide; CLRP; C-type lectin-related protein; CNG channel; cyclic nucleotide-gated channel; CRiSP; cysteine-rich secreted protein
Paving the Rho in cancer metastasis: Rho GTPases and beyond
Keywords: G-پروتئین همراه گیرنده; ADP; adenosine diphosphate; AMP; adenosine monophosphate; AMT; amoeboid-mesenchymal transition; APC; adenomatosis polyposis coli; Arp2/3; actin related protein 2/3; Cdc42; cell division control protein 42 homolog; CK1; casein kinase 1; COX-2; cyclooxygena
Effect fingerprinting of new psychoactive substances (NPS): What can we learn from in vitro data?
Keywords: G-پروتئین همراه گیرنده; 2C-B; 2,5-Dimethoxy-4-bromophenethylamine; 4-FA; 4-Fluoroamphetamine; 4-MEC; 4-Methylethcathinone; 4-MMC; 4-Methylmethcathinone, a.k.a. mephedrone; 5-APB; 5-(2-Aminopropyl)benzofuran; 6-APB; 6-(2-Aminopropyl)benzofuran; 5-HT; Serotonin; 25B-NBOMe; 4-Bromo
Identification, signaling, and functions of LTB4 receptors
Keywords: G-پروتئین همراه گیرنده; AA; arachidonic acid; CLDN4; claudin-4; COX; cyclooxygenase; DGS3; desmoglein-3; DSS; dextran sodium sulfate; 5-LOX; 5-lipoxygenase; 5(S)-HETE; 5(S)-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid; 5(S)-HpETE; 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic a
UDP/P2Y6 receptor signaling regulates IgE-dependent degranulation in human basophils
Keywords: G-پروتئین همراه گیرنده; Basophil; IgE-dependent degranulation; MRS2578; P2Y6; UDP; P2YR; P2Y purinergic receptors; GPCR; G-protein coupled receptor; ENTPDase; ecto-nucleoside triphosphate diphosphohydrolase; AC; adenylate cyclase; PLC; phospholipase C; PKC; protein kinase C; MFI
Kynurenic acid and its analogue can alter the opioid receptor G-protein signaling after acute treatment via NMDA receptor in rat cortex and striatum
Keywords: G-پروتئین همراه گیرنده; KYNA; Opioid receptor; [35S]GTPγS binding; G-protein; MK-801; 3-NLT; 3-nitro-l-tyrosine; CNS; central nerve system; CSF; cerebrospinal fluid; BBB; blood-brain barrier; DAMGO; Tyr-D-Ala-Gly-(NMe)Phe-Gly-ol; DOPr; δ opioid peptide receptor; EGTA; ethylene
Recent advances in biophysical studies of rhodopsins - Oligomerization, folding, and structure
Keywords: G-پروتئین همراه گیرنده; AFM; Atomic Force Microscopy; apolipoprotein A-I; apolipoprotein A1; ASR; Anabaena sensory rhodopsin; BN-PAGE; blue native - polyacrylamide gel electrophoresis; BPR; blue-absorbing proteorhodopsin; BO; bacterioopsin; BR; bacteriorhodopsin; CD; Circular Di
Stimulation of lactate receptor (HCAR1) affects cellular DNA repair capacity
Keywords: G-پروتئین همراه گیرنده; HCAR1; hydroxycarboxylic acid receptor 1; GPCR; G-protein coupled receptor; BRCA1; breast cancer type 1 susceptibility protein; NBS1; Nijmegen breakage syndrome 1; PRKDC; protein kinase DNA-activated catalytic polypeptide; DNA-PKcs; DNA-dependent protein
CXCR4 and CXCR7 play distinct roles in cardiac lineage specification and pharmacologic β-adrenergic response
Keywords: G-پروتئین همراه گیرنده; CXCR4; CXCR7; Cardiogenesis; hiPSC; Engineered tissue; hiPSC; human induced pluripotent stem cell; hiPSC-CM; human induced pluripotent stem cell-derived cardiomyocyte; hECT; human engineered cardiac tissue; GPCR; G-protein coupled receptor; SDF-1; stromal
Apela exhibits isoform- and headgroup-dependent modulation of micelle binding, peptide conformation and dynamics
Keywords: G-پروتئین همراه گیرنده; AR; apelin receptor (APJ); CCSD; combined chemical shift displacement; CD; circular dichroism; CSI; chemical shift index; DANGLE; Dihedral Angles from Global Likelihood Estimates; DOSY; diffusion ordered spectroscopy; DPC; dodecylphosphocholine; DSS; 2,2-
Reprint of Pharmacological and molecular characterization of the positive allosteric modulators of metabotropic glutamate receptor 2
Keywords: G-پروتئین همراه گیرنده; Metabotropic glutamate receptor; mGlu2; mGlu3; mGluR; Negative allosteric modulators; Positive allosteric modulators; LY354740; LY487379; ECL; extracellular loop; FLIPR; Fluorometric Imaging Plate Reader; GPCR; G-protein coupled receptor; mGluR; metabotro
Complexity of the Wnt/βâcatenin pathway: Searching for an activation model
Keywords: G-پروتئین همراه گیرنده; APC; adenomatous polyposis coli; BCL-9; B-cell lymphoma 9; BMPs; bone morphogenetic proteins; CARM; coactivator-associated arginine methyltransferase; CBP; CREB-binding protein; CK1α; casein kinase 1α; CRD; Cysteine-Rich Domain; DIX; Dishevelled interac
Regular ArticlesWISH, a novel CFEM GPCR is indispensable for surface sensing, asexual and pathogenic differentiation in rice blast fungus
Keywords: G-پروتئین همراه گیرنده; CFEM; G-protein coupled receptor; Magnaporthe oryzae; Rice blast; Surface sensing; Pathogenesis;
Synthesis and evaluation of (E)-2-(5-phenylpent-2-en-4-ynamido)cyclohex-1-ene-1-carboxylate derivatives as HCA2 receptor agonists
Keywords: G-پروتئین همراه گیرنده; LDL; low-density lipoprotein; HDL; high-density lipoprotein; cAMP; 3â²-5â²-cyclic adenosine monophosphate; SAR; structure-activity relationship; RLB; radioligand binding; GPCR; G-protein coupled receptor; BSA; bovine serum albumin; DCM; dichloromethane;
Neuropeptide Y Y5 receptor localization in mouse central nervous system
Keywords: G-پروتئین همراه گیرنده; Specificity of antibody; G-protein coupled receptor; Knockout mouse, obesity;
Regions of MRAP2 required for the inhibition of orexin and prokineticin receptor signaling
Keywords: G-پروتئین همراه گیرنده; MRAP1/2; melanocortin accessory receptor 1/2; GPCR; G-protein coupled receptor; PKR 1/2; prokineticin receptor 1/2; OX1R; orexin receptor 1; MC2/4R; melanocortin-2/4 receptor; CHO; Chinese hamster ovary; YFP; yellow fluorescent protein; ALP; alkaline phos
Chronic intermittent ethanol exposure selectively alters the expression of Gα subunit isoforms and RGS subtypes in rat prefrontal cortex
Keywords: G-پروتئین همراه گیرنده; GPCR; G-protein coupled receptor; RGS; regulator of G-protein signaling; GIRK; G protein-coupled inwardly-rectifying potassium channel; CIE; chronic intermittent ethanol/24Â h withdrawal; PFC; prefrontal cortex; LTD; long-term depression; Chronic intermit
Cytochrome P450-derived eicosanoids and heart function
Keywords: G-پروتئین همراه گیرنده; AA; arachidonic acid; ACS; acute coronary syndrome; ALA; alpha-linolenic acid; AMI; acute myocardial infarction; AMPK; 5â² adenosine monophosphate-activated protein kinase; Ang II; angiotensin II; ANP; atrial natriuretic peptide; BaP; benzo(α)pyrene; BK
Endothelin-1 promotes hypertrophic remodelling of cardiac myocytes by activating sustained signalling and transcription downstream of endothelin type A receptors
Keywords: G-پروتئین همراه گیرنده; Endothelin-1; Cardiac hypertrophy; Signalling; MAPK; GPCRs; Act D; actinomycin D; Ang II; angiotensin II; ANF; atrial natriuretic factor; BNP; brain natriuretic factor; CN; calcineurin; CVD; cardiovascular disease; ara-C; cytosine b-d-arabinofuranoside; D