دانلود مقالات ISI درباره مطالعه مرتبط با ژنوم + ترجمه فارسی

The environment, epigenome, and asthma

Keywords: مطالعه مرتبط با ژنوم; Asthma; DNA methylation; epigenetics; nasal epithelium; microbiome; air pollution; allergens; DMR; Differentially methylated region; GF; Germ-free; GWAS; Genome-wide association study; OVA; Ovalbumin; PAH; Polyaromatic hydrocarbon; PM; Particulate matter;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

IRF4 Polymorphism Is Associated with Cutaneous Squamous Cell Carcinoma in Organ Transplant Recipients: A Pigment-Independent Phenomenon

Keywords: مطالعه مرتبط با ژنوم; cSCC; cutaneous squamous cell carcinoma; GWAS; genome-wide association study; HR; hazard ratio; OTR; organ transplant recipient; SNP; single-nucleotide polymorphism;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

High-throughput screening and bioinformatic analysis to ascertain compounds that prevent saturated fatty acid-induced β-cell apoptosis

Keywords: مطالعه مرتبط با ژنوم; MAP4K4; mitogen-activated protein kinase kinase kinase kinase 4; PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; KIEN; Kinase Inhibitors Elastic Net; GWAS; genome-wide association study; Islet; Diabetes; Beta-cell; Lipotoxic

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Liver immunology: How to reconcile tolerance with autoimmunity

Keywords: مطالعه مرتبط با ژنوم; PPR; pattern recognition receptor; HBV; hepatitis B virus; HCV; hepatitis C virus; TLR; toll-like receptor; IFN; interferon; LSEC; liver sinusoidal endothelial cell; APC; antigen presenting cell; MHC; major histocompatibility complex; PDL-1; program death

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Pharmacogenomics: Precision Medicine and Drug Response

Keywords: مطالعه مرتبط با ژنوم; CYP; cytochrome P450; EHR; electronic health record; eMERGE; Electronic Medical Records and Genomics; GWAS; genome-wide association study; NGS; next-generation sequencing; NIH; National Institutes of Health; ns; nonsynonymous; PGRN; Pharmacogenomics Resea

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study

Keywords: مطالعه مرتبط با ژنوم; Medication; Liver Damage; Side Effect; Anti-Fungal Agent; AF; allele frequency; CM; cholestatic-mixed; DILI; drug-induced liver injury; DILIN; Drug-Induced Liver Injury Network; GWAS; genome-wide association study; HC; hepatocellular; iDILIC; Internationa

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Transcribing β-cell mitochondria in health and disease

Keywords: مطالعه مرتبط با ژنوم; β-Cell; Mitochondria; Islets; Genome-wide association study (GWAS); Insulin secretion; Expression quantitative trait locus (eQTL); ATGL; adipocyte triglyceride lipase; AMPK; AMP-dependent protein kinase; COX; Cytochrome c oxidase; CYTB; Cytochrome b; ERR

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewGenetic polymorphisms and lung cancer risk: Evidence from meta-analyses and genome-wide association studies

Keywords: مطالعه مرتبط با ژنوم; Lung cancer; Polymorphisms; Meta-analysis; Genome-wide association study;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Multiple Functional Variants of IFIH1, a Gene Involved in Triggering Innate Immune Responses, Protect against Vitiligo

Keywords: مطالعه مرتبط با ژنوم; GWAS; genome-wide association study; IFIH1; interferon-induced helicase C domain 1 protein; OR; odds ratio; SNP; single-nucleotide polymorphism;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Genome-Wide Association Study Identifies Risk Variants for Lichen Planus in Patients With Hepatitis C Virus Infection

Keywords: مطالعه مرتبط با ژنوم; Inflammation; Risk Factor; Oral Mucosa; Autoimmunity; CI; confidence interval; GWAS; genome-wide association study; HCV; hepatitis C virus; IFN; interferon; IGF; insulin-like growth factor; LP; lichen planus; OLP; oral lichen planus; OR; odds ratio; RCC;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

A Genome-Wide Association Study of Basal Transepidermal Water Loss Finds that Variants at 9q34.3 Are Associated with Skin Barrier Function

Keywords: مطالعه مرتبط با ژنوم; AD; atopic dermatitis; GWAS; genome-wide association study; LD; linkage disequilibrium; SNP; single-nucleotide polymorphism; TEWL; transepidermal water loss;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

What Genetics Tells Us About the Pathogenesis of IgA Nephropathy: The Role of Immune Factors and Infection

Keywords: مطالعه مرتبط با ژنوم; genetic predisposition; genome-wide association study; IgA nephropathy; mucosal infection;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

The genetic and biological basis of feed efficiency in mid-lactation Holstein dairy cows

Keywords: مطالعه مرتبط با ژنوم; genome-wide association study; residual feed intake; feed efficiency; dairy;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Melanoma Expression Genes Identified through Genome-Wide Association Study of Breslow Tumor Thickness

Keywords: مطالعه مرتبط با ژنوم; GWAS; genome-wide association study; IHC; immunohistochemical; MDACC; MD Anderson Cancer Center; MELARISK; the French Melanoma Risk study; TMA; tissue microarray;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

What can time-frequency and phase coherence measures tell us about the genetic basis of P3 amplitude?

Keywords: مطالعه مرتبط با ژنوم; Genome-wide association study; Endophenotype; P300; Heritability; Time-frequency energy; Inter-trial phase coherence;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Scanning indels in the 5q22.1 region and identification of the TMEM232 susceptibility gene that is associated with atopic dermatitis in the Chinese Han population

Keywords: مطالعه مرتبط با ژنوم; AD; Atopic dermatitis; IHC; Immunohistochemistry; GWAS; Genome-wide association study; TMEM232; Transmembrane protein 232; SLC25A46; Solute carrier family 25 member 46; indels; Insertion and deletions; Atopic dermatitis; TMEM232; Deletion; Expression;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Association of a novel genetic variant in RP11-650L12.2 with risk of colorectal cancer in Han Chinese population

Keywords: مطالعه مرتبط با ژنوم; lncRNA; long non-coding RNA; CRC; colorectal cancer; CCAT; CRC-associated transcript; COPD; chronic obstructive pulmonary diseases; HOTAIR; HOX transcript antisense RNA; GWAS; genome-wide association study; G × E; gene by environment; MAF; minor allele

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Integrated late onset Alzheimer's disease (LOAD) susceptibility genes: Cholesterol metabolism and trafficking perspectives

Keywords: مطالعه مرتبط با ژنوم; Aβ; Amyloid-β; AD; Alzheimer's disease; ApoE; Apolipoprotein E; APP; Amyloid precursor protein; BBB; Blood brain barrier; CLU; Clusterin; CNS; Central nervous system; CSF; Cerebrospinal fluid; DMN; Default mode network; EOAD; Early onset Alzheimer's dis

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Genetic Variants in WNT2B and BTRC Predict Melanoma Survival

Keywords: مطالعه مرتبط با ژنوم; adjHR; adjusted hazards ratio; BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase; CI; confidence interval; CM; cutaneous melanoma; CMSS; cutaneous melanoma-specific survival; GWAS; genome-wide association study; MDACC; MD Anderson Cancer

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Metabolomics applied to diabetes−lessons from human population studies

Keywords: مطالعه مرتبط با ژنوم; α −HB; α−hydroxybutyrate; AAAs; aromatic amino acids; BCAA; branched-chain amino acids; BCKA; branched-chains keto acids; CHSc; cardiovascular health study; YFS; cardiovascular risk in young finns study; DPA; docosapentaenoate; DFTJ; Dongfeng-Tongji

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Two obesity susceptibility loci in LYPLAL1 and ETV5 independently associated with childhood hypertension in Chinese population

Keywords: مطالعه مرتبط با ژنوم; BMI; body mass index; GWAS; genome-wide association study; SNP; single-nucleotide polymorphism; WC; waist circumference; WtHR; waist-to-height ratio; SD; standard deviations; GRS; genetic risk score; SBP; systolic blood pressure; DBP; diastolic blood pres

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Association of Ribonuclease T2 Gene Polymorphisms With Decreased Expression and Clinical Characteristics of Severity in Crohn's Disease

Keywords: مطالعه مرتبط با ژنوم; SNP; Prognosis; Genetics; Risk Factor; CD; Crohn's disease; eQTL; expression quantitative trait loci; GWAS; genome-wide association study; IBD; inflammatory bowel diseases; ICAM1; intercellular adhesion molecule 1; IFNG; interferon gamma; IIBDGC; Intern

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

6q12 and 11p14 variants are associated with postnatal exhaled nitric oxide levels and respiratory symptoms

Keywords: مطالعه مرتبط با ژنوم; Infants; exhaled nitric oxide; genetics; airway inflammation; genome-wide association study; wheeze; asthma; ANO3; Human anoctamin 3 gene locus; CTCF; CCCTC-binding factor; DENND1B; DENN/MADD domain containing 1B; EGF; Epithelial growth factor; eNO; Exhal

دانلود رایگان متن کامل مقاله ISI 79 صفحه سال انتشار : 2017 سفارش ترجمه

Genome-Wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection

Keywords: مطالعه مرتبط با ژنوم; Genetics; Liver Cancer; Mutation; Metalloprotease; AFP; α-fetoprotein; anti-HBc; antibody to hepatitis B core antigen; BMP1; bone morphogenetic protein 1; CCl4; carbon tetrachloride; CDAA; choline-deficient L-amino acid-defined; CHC; chronic hepatitis C;

دانلود رایگان متن کامل مقاله ISI 79 صفحه سال انتشار : 2017 سفارش ترجمه

Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer

Keywords: مطالعه مرتبط با ژنوم; BMI; body mass index; CCFR; Colon Cancer Family Registry; CI; confidence interval; FTO; fat-mass and obesity-associated; GECCO; Genetics and Epidemiology of Colorectal Cancer Consortium; GWAS; genome-wide association study; MAF; minor allele frequency; MC

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Schizophrenia risk variants affecting microRNA function and site-specific regulation of NT5C2 by miR-206

Keywords: مطالعه مرتبط با ژنوم; Schizophrenia; Genome-wide association study; MicroRNA; Single nucleotide polymorphism; miR-206; and NT5C2;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

DNA methylation within melatonin receptor 1A (MTNR1A) mediates paternally transmitted genetic variant effect on asthma plus rhinitis

Keywords: مطالعه مرتبط با ژنوم; Linkage analysis; positional cloning; asthma; allergic rhinitis; parent-of-origin effect; DNA methylation; genetic association study; AAR; Asthma and allergic rhinitis comorbidity; AR; Allergic rhinitis; CIT; Causal inference test; CNG; Centre National de

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

The SNP rs1625579 in miR-137 gene and risk of schizophrenia in Chinese population: A meta-analysis

Keywords: مطالعه مرتبط با ژنوم; miRNAs; microRNAs; GWAS; genome-wide association study; SNP; single nucleotide polymorphism; GSEA; gene set enrichment analysis; PRISMA; Preferred Reporting Items for Systematic Reviews and Meta-Analysis; DSM-IV; Diagnosis and Statistical Manual of Mental

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

One SNP at a Time: Moving beyond GWAS in Psoriasis

Keywords: مطالعه مرتبط با ژنوم; ChIP; chromatin immunoprecipitation; eQTL; expression quantitative trait locus; GPP; generalized pustular psoriasis; GWAS; genome-wide association study; LCE; late cornified envelope; LD; linkage dysequilibrium; MHC; major histocompatibility complex; SNP;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Nonsyndromic cleft lip with or without cleft palate and cancer: Evaluation of a possible common genetic background through the analysis of GWAS data

Keywords: مطالعه مرتبط با ژنوم; Cleft lip; Cleft palate; Genome-wide association study; Single nucleotide polymorphism; Cancer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Genome-wide association study of 25(OH) Vitamin D concentrations in Punjabi Sikhs: Results of the Asian Indian diabetic heart study

Keywords: مطالعه مرتبط با ژنوم; Vitamin D deficiency; 25(OH)D levels (ELISA); Type 2 diabetes; Genome-wide association study; Punjabi Sikhs;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28 Day Mortality

Keywords: مطالعه مرتبط با ژنوم; Sepsis; Host response; Genome-wide association study; Mortality; Exome;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Variants in the autophagy-related gene IRGM confer susceptibility to non-alcoholic fatty liver disease by modulating lipophagy

Keywords: مطالعه مرتبط با ژنوم; NAFLD; non-alcoholic fatty liver disease; GWAS; genome-wide association study; PNPLA3; patatin-like phospholipase domain-containing-3; TM6SF2; transmembrane 6 superfamily member 2; GCKR; glucokinase regulatory protein; IRGM; immunity-related GTPase family

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Optimizing R with SparkR on a commodity cluster for biomedical research

Keywords: مطالعه مرتبط با ژنوم; Computing methodologies; Genome-wide association study; Big data; Cluster computing; SparkR;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Race differences in IQ: Hans Eysenck's contribution to the debate in the light of subsequent research

Keywords: مطالعه مرتبط با ژنوم; Black-White IQ gap; Genetics; Genome-wide association study; Heritability; H. J. Eysenck; Intelligence; Racial admixture; Racial crossing;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

AIRE genetic variants and predisposition to polygenic autoimmune disease: The case of Graves' disease and a systematic literature review

Keywords: مطالعه مرتبط با ژنوم; AIRE; Autoimmune regulator; TRA; Tissue-restricted antigen; APECED; Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy; SNP; Single nucleotide polymorphism; TSHR; Thyroid stimulating hormone receptor; GWAS; Genome-wide association study; pGE;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Genome-wide association meta-analyses identified 1q43 and 2q32.2 for hip Ward's triangle areal bone mineral density

Keywords: مطالعه مرتبط با ژنوم; Hip Ward's triangle; Bone mineral density; Genome-wide association study; Meta-analysis; GREM2; NAB1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Genetics links between transforming growth factor β pathway and coronary disease

Keywords: مطالعه مرتبط با ژنوم; Coronary artery disease; Atherosclerosis; Transforming growth factor β pathway; Genome-wide association study; Genetic risk loci;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Heritability and genome-wide association mapping for supernumerary teats in French Alpine and Saanen dairy goats

Keywords: مطالعه مرتبط با ژنوم; supernumerary teat; goat; genome-wide association study;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Original ResearchFull Report: Basic and Translational-Alimentary TractVariants in TRIM22 That Affect NOD2 Signaling Are Associated With Very-Early-Onset Inflammatory Bowel Disease

Keywords: مطالعه مرتبط با ژنوم; VEOIBD; NF-kB; Antiviral and Antibacterial Networks; eQTL; expression quantitative trait loci; GWAS; genome-wide association study; MDP; muramyl dipeptide; NF-κB; nuclear factor−κB; NOD2; nucleotide binding oligomerization domain containing 2; RSV; to

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of stable QTLs for seed oil content by combined linkage and association mapping in Brassica napus

Keywords: مطالعه مرتبط با ژنوم; QTL; quantitative trait locus; SNP; single nucleotide polymorphism; GWAS; genome-wide association study; RFLP; restriction fragment length polymorphism; RAPD; random amplified polymorphic DNA; AFLP; amplified fragment length polymorphism; CAPS; cleaved am

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

THBS2 Is a Candidate Modifier of Liver Disease Severity in Alagille Syndrome

Keywords: مطالعه مرتبط با ژنوم; JAG1; NOTCH2; Gene Modifier; Cholestasis; Genome-Wide Association Study; ALGS; Alagille syndrome; BSA; bovine serum albumin; cDNA; complementary DNA; ChiLDReN; Childhood Liver Disease Research Network; CK19; cytokeratin 19; ddPCR; droplet digital polymera

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF

Keywords: مطالعه مرتبط با ژنوم; IBD; Inflammatory Bowel Disease; Risk Factor; Ethnic Variation; AJ; Ashkenazi Jewish; AKT; AK strain transforming; CD; Crohn's disease; CRC; colorectal cancer; CSF2RA; CSF-receptor, α chain; CSF2RB; CSF-receptor, β chain; CyTOF; time-of-flight mass cyto

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Everolimus (RAD001) ameliorates vascular cognitive impairment by regulating microglial function via the mTORC1 signaling pathway

Keywords: مطالعه مرتبط با ژنوم; VaD; vascular dementia; mTORC1; mammalian target of rapamycin complex 1; AD; Alzheimer's disease; ROS; reactive oxygen species; GWAS; genome-wide association study; IFN; interferon; TNF-α; tumor necrosis factor alpha; IL; interleukin; Arg-1; arginase-1;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

Genome-wide association study confirms lung cancer susceptibility loci on chromosomes 5p15 and 15q25 in an African-American population

Keywords: مطالعه مرتبط با ژنوم; Genome-wide association study; Lung neoplasms; Smoking; African Americans; Telomerase; Receptors, Cholinergic;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

Genetic variants and risk of esophageal squamous cell carcinoma: A GWAS-based pathway analysis

Keywords: مطالعه مرتبط با ژنوم; ESCC; esophageal squamous cell carcinoma; EC; esophageal cancer; SNP; single nucleotide polymorphism; GWAS; genome-wide association study; ICSNPathway; the identify candidate causal SNPs and pathways; LD; linkage disequilibrium; PBA; pathway-based analysi

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Chromosome 12p13 variants contribute to large artery atherosclerotic stroke risk in a Chinese population

Keywords: مطالعه مرتبط با ژنوم; GWAS; genome-wide association study; SNP; single nucleotide polymorphism; LAA; large artery atherosclerotic; LD; linkage disequilibrium; Chromosome 12p13; Polymorphism; Susceptibility; Stroke; GWAS; Genetics;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Meta-analysis of data from the Psychiatric Genomics Consortium and additional samples supports association of CACNA1C with risk for schizophrenia

Keywords: مطالعه مرتبط با ژنوم; Schizophrenia; Genome-wide association study; PGC; Follow-up study; Meta-analysis; CACNA1C;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Single nucleotide polymorphisms near the inhibin beta B gene on 2q14 are associated with pre-eclampsia in Han Chinese women

Keywords: مطالعه مرتبط با ژنوم; SNP; Pre-eclampsia; Genome-wide association study; INHBB

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Assessment of association between genetic variants in microRNA genes hsa-miR-499, hsa-miR-196a2 and hsa-miR-27a and prostate cancer risk in Serbian population

Keywords: مطالعه مرتبط با ژنوم; PCa; prostate cancer; BPH; benign prostatic hyperplasia; GWAS; genome-wide association study; PSA; prostate-specific antigen; GS; Gleason score; PCR-RFLP; restriction fragment length polymorphism analysis of PCR-amplified fragments; HRMA; high resolutio

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه