کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6075032 1203492 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
One SNP at a Time: Moving beyond GWAS in Psoriasis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی امراض پوستی
پیش نمایش صفحه اول مقاله
One SNP at a Time: Moving beyond GWAS in Psoriasis
چکیده انگلیسی
Although genome-wide association studies have revealed important insights into the global genetic basis of psoriasis, the findings require further investigation. At present, the known genetic risk loci are largely uncharacterized in terms of the variant or gene responsible for the association, the biological pathway involved, and the main cell type driving the pathology. This review primarily focuses on current approaches toward gaining a complete understanding of how these known genetic loci contribute to an increased disease risk in psoriasis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Investigative Dermatology - Volume 136, Issue 3, March 2016, Pages 567-573
نویسندگان
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