Keywords: ژنوتیپ 1; Hepatitis C; Genotype 1; Direct-acting antivirals; Second generation; Resistance-associated variants;
مقالات ISI ژنوتیپ 1 (ترجمه نشده)
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Keywords: ژنوتیپ 1; Chronic hepatitis C; Genotype 1; Sofosbuvir; Cost–effectivenessHepatitis C crónica; Genotipo 1; Sofosbuvir; Coste-efectividad
Antiviral Activity, Safety, and Tolerability of Multiple Ascending Doses of Elbasvir or Grazoprevir in Participants Infected With Hepatitis C Virus Genotype-1 or -3
Keywords: ژنوتیپ 1; elbasvir; genotype 1; genotype 3; grazoprevir; hepatitis C virus; monotherapy;
Antiviral response and resistance analysis of treatment-naïve HCV infected patients receiving multiple doses of the NS3 protease inhibitor GS-9256
Keywords: ژنوتیپ 1; Phase 1 monotherapy study; Drug resistance profile; Genotype 1; Sequencing; DAAs; Direct acting antivirals; PI; protease inhibitor; RAS; resistance associated substitution; SVR; sustained virologic response;
Safety and efficacy of daclatasvir-sofosbuvir in HCV genotype 1-mono-infected patients
Keywords: ژنوتیپ 1; Chronic hepatitis C; Treatment; Sofosbuvir; Daclatasvir; Direct antiviral agents; Cirrhosis; Severe fibrosis; Genotype 1; Hepather cohort;
Effectiveness, safety and clinical outcomes of direct-acting antiviral therapy in HCV genotype 1 infection: Results from a Spanish real-world cohort
Keywords: ژنوتیپ 1; Hepatitis C, Chronic; Genotype 1; Ombitasvir; Paritaprevir; Ritonavir; Dasabuvir; Ledipasvir; Sofosbuvir; Real-world; Antiviral agents; Sustained virologic response; Randomized controlled trials;
Role of IL28B genotype in the liver stiffness increase in untreated patients with chronic hepatitis C
Keywords: ژنوتیپ 1; CHC; chronic hepatitis C; HCV; Hepatitis C virus; PEG-IFN; pegylated interferon alfa; RBV; ribavirin; DAAs; direct-acting antiviral agents; GT1; genotype 1; GT4; genotype 4; IQR; inter-quartile range; OR; odds ratio; HCV; IL28B; Liver stiffness; Fibrosis
Suppressor of cytokine signaling 1 expression in peripheral blood mononuclear cells of hepatitis C genotype 1 patients
Keywords: ژنوتیپ 1; genotype 1; hepatitis C virus; interferon-α; JAK/STAT signaling; suppressor of cytokine signaling 1
Distinguishing the genotype 1 genes and proteins of human Wa-like rotaviruses vs. porcine rotaviruses
Keywords: ژنوتیپ 1; Group A rotavirus; Genomics; Porcine; Human; Genotype 1; Sub-genotypic diversity; Amino acid changes; Host tropism
Research ArticleVirology analyses of HCV isolates from genotype 1-infected patients treated with simeprevir plus peginterferon/ribavirin in Phase IIb/III studies
Keywords: ژنوتیپ 1; HCV; hepatitis C virus; PR; peginterferon and ribavirin; QD; once-daily; GT; genotype; SVR; sustained virologic response; DAA; direct-acting antiviral agent; EC50; half maximal effective concentration; EOS; end of study; Hepatitis C virus; Genotype 1; Onc
Boceprevir for Chronic Genotype 1 Hepatitis C Virus in the Current Health Care Setting in Greece: A Cost-effectiveness Analysis
Keywords: ژنوتیپ 1; boceprevir; chronic hepatitis C; cost-effectiveness; genotype 1; pegylated interferon; ribavirin;
Mechanisms of Virologic Failure with Direct-Acting Antivirals in Hepatitis C and Strategies for Retreatment
Keywords: ژنوتیپ 1; Hepatitis C; Retreatment; Genotype 1; Direct-acting antivirals (DAAs); Resistance-associated variants (RAVs); Protease inhibitor; RNA-polymerase inhibitor; NS5A inhibitor;
Research ArticleSteatosis affects the performance of liver stiffness measurement for fibrosis assessment in patients with genotype 1 chronic hepatitis C
Keywords: ژنوتیپ 1; AUROC; area under roc curve; BLEP; bright liver echo pattern; CHC; chronic hepatitis C; G1; genotype 1; LR; likelihood ratio; LSM; liver stiffness measurement; TE; transient elastography; US; ultrasonography; Evaluation; Non-invasive; Fibroscan®; Ultraso
Research ArticleShould we await IFN-free regimens to treat HCV genotype 1 treatment-naive patients? A cost-effectiveness analysis (ANRS 95141)
Keywords: ژنوتیپ 1; Boceprevir; Chronic hepatitis C; Cost-effectiveness analysis; Direct-acting antivirals; Genotype 1; Interferon-free regimens; Model-based analysis; Telaprevir; Treatment initiation; G1; genotype 1; HCV; hepatitis C virus; TVR; telaprevir; BOC; boceprevir;
Body Mass Index and Liver Stiffness Affect Accuracy of Ultrasonography in Detecting Steatosis in Patients With Chronic Hepatitis C Virus Genotype 1 Infection
Keywords: ژنوتیپ 1; BLEP; Fibrosis; Evaluation; Cirrhosis; ALT; alanine aminotransferase; BMI; body mass index; CHC; chronic hepatitis C; CI; confidence interval; G1; genotype 1; HCV; hepatitis C virus; HOMA; homeostasis model assessment; LR; likelihood ratio; LSM; liver sti
The Combination of MK-5172, Peginterferon, and Ribavirin Is Effective in Treatment-Naive Patients With Hepatitis C Virus Genotype 1 Infection Without Cirrhosis
Keywords: ژنوتیپ 1; Response-Guided Therapy; Sustained Virologic Response; Chronic HCV; Protease Inhibitor; ADME; absorption, distribution, metabolism, and excretion; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BOC; boceprevir; cEVR; complete early virolo
Proteomic characterization of hepatitis C eradication: Enzyme switch in the healing liver
Keywords: ژنوتیپ 1; Antiviral therapy; FFPE; Genotype 1; HCV; Insulin resistance; Metabolism proteomics;
Research ArticleIndustrial, not fruit fructose intake is associated with the severity of liver fibrosis in genotype 1 chronic hepatitis C patients
Keywords: ژنوتیپ 1; Fructose; Chronic hepatitis C; Liver fibrosis; HCV; hepatitis C virus; G1; genotype 1; CHC; chronic hepatitis C; WC; waist circumference; DCL; dorso-cervical lipohypertrophy; WHR; waist-to-hip ratio;
Research ArticleCost-effectiveness of boceprevir or telaprevir for previously treated patients with genotype 1 chronic hepatitis C
Keywords: ژنوتیپ 1; CHC; chronic hepatitis C; G1; genotype 1; DT; dual therapy; PegIFN; pegylated interferon; RBV; ribavirin; PI; protease inhibitors; BOC; boceprevir; TVR; telaprevir; ICER; incremental cost-effectiveness ratio; NR; non-response; PAR; partial response; RR; r
Preparing the patient for success: Treat or wait?
Keywords: ژنوتیپ 1; Hepatitis C; Genotype 1; Wait; Treat
No beneficial effect of all-trans retinoic acid in previous non-responder patients with chronic hepatitis C: The ATRACTION study, a phase II randomised trial
Keywords: ژنوتیپ 1; All-trans retinoic acid; Chronic hepatitis C; Efficacy; Genotype 1; Mathematical model of viral kinetics; Non-response; Randomised clinical trial; Safety; Tolerability
Indicaciones actuales de tratamiento triple para la hepatitis C
Keywords: ژنوتیپ 1; Virus de la hepatitis C; Genotipo 1; Boceprevir; Telaprevir; Respuesta viral sostenidaHepatitis C virus; Genotype 1; Boceprevir; Telaprevir; Sustained viral response
Posibilidades actuales para predecir la respuesta a la terapia en pacientes con hepatitis C crónica por el genotipo 1 del virus de la hepatitis C
Keywords: ژنوتیپ 1; Virus de la hepatitis C; Genotipo 1; Interferón alfa pegilado; Predicción de la respuesta a la terapia; Modelos multivariantes; Hepatitis C virus; Genotype 1; Pegylated interferon alfa; Treatment response prediction; Multivariate models;
Research ArticleThe efficacy and safety of pegylated interferon plus ribavirin combination therapy in chronic hepatitis c patients with hepatocellular carcinoma post curative therapies - A multicenter prospective trial
Keywords: ژنوتیپ 1; HCV; hepatitis C virus; CHC; chronic HCV infection; HCC; hepatocellular carcinoma; PegIFN; pegylated interferon; RBV; ribavirin; LC; liver cirrhosis; G-1; genotype 1; G-2/3; genotype 2 or 3; SVR; sustained virological response; RVR; rapid virological resp
Management of the Treatment-Experienced Patient Infected with Hepatitis C Virus Genotype 1: Options and Considerations
Keywords: ژنوتیپ 1; Hepatitis C; Consensus interferon; Genotype 1; NS3 protease inhibitor; Boceprevir; Telaprevir; IL-28B polymorphism; Difficult-to-treat patients;
Research ArticleNatural history of chronic hepatitis C: Genotype 1 versus genotype 6
Keywords: ژنوتیپ 1; Hepatitis C; Genotype 1; Genotype 6; Natural history; Cirrhosis; Mortality;
Quasispecies of hepatitis C virus genotype 1 and treatment outcome with Peginterferon and Ribavirin
Keywords: ژنوتیپ 1; Hepatitis C virus; Genotype 1; Quasispecies; Nonstructural 5A region; Pegylated interferon; Ribavirin; Sequence analysis
High predictive value of early viral kinetics in retreatment with peginterferon and ribavirin of chronic hepatitis C patients non-responders to standard combination therapy
Keywords: ژنوتیپ 1; Predictive factors; Genotype 1; Early virological response; Cirrhosis; Side effectsCHC, chronic hepatitis C; PEG-IFN, peginterferon; RBV, ribavirin; RVR, rapid virological response; EVR, early virological response; EOT, end of treatment; SVR, sustained vi
Randomized, double-blind, placebo-controlled study of peginterferon alfa-2a (40KD) plus ribavirin with or without amantadine in treatment-naïve patients with chronic hepatitis C genotype 1 infection
Keywords: ژنوتیپ 1; Chronic hepatitis C; Genotype 1; Antiviral therapy; Amantadine
A phase 2 study to evaluate the antiviral activity, safety, and pharmacokinetics of recombinant human albumin-interferon alfa fusion protein in genotype 1 chronic hepatitis C patients
Keywords: ژنوتیپ 1; Albumin-interferon alfa; Chronic hepatitis C; Genotype 1; Pharmacokinetics; Viral kinetics
Cell-based models of sustained, interferon-sensitive hepatitis C virus genotype 1 replication
Keywords: ژنوتیپ 1; Hepatitis C virus; HCV; Replication; Genotype 1; Adenovirus vector; Huh-T7