دانلود مقالات ISI درباره Ggti + ترجمه فارسی

سیمواستاتین مانع از ایزوپرانیلیت پروتئین در مغز می شود

Simvastatin inhibits protein isoprenylation in the brain

Keywords: 2D; two-dimensional; AD; Alzheimer's disease; APP; amyloid precursor protein; FPP; farnesyl pyrophosphate; GGPP; geranylgeranyl pyrophosphate; GGT; geranylgeranyl transferase; GGTI; GGT inhibitor; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic aci

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Simvastatin inhibits CD44 fragmentation in chondrocytes

Keywords: Chondrocyte; Pericellular matrix; Statin; CD44; Lipid raft; ADAM10; HA; hyaluronan; OA; osteoarthritis; OSM; Oncostatin M; BAC; bovine articular chondrocytes; HAC; human articular chondrocytes; MT1-MMP; membrane type I metalloproteinase; ICD; intracellula

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Simvastatin induces insulin resistance in L6 skeletal muscle myotubes by suppressing insulin signaling, GLUT4 expression and GSK-3β phosphorylation

Keywords: Simvastatin; Glucose uptake; Glucose transporter 4; IR-Dependent IRS-1/PI3K/Akt pathway; L6 myotubes; FPP; farnesyl pyrophosphate; FTI; farnesyltransferase inhibitor; GGPP; geranylgeranyl pyrophosphate; GGTI; geranylgeranyltransferase 1 inhibitor; GLUT4;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

Prenylation differentially inhibits insulin-dependent immediate early gene mRNA expression

Keywords: Insulin; Gene expression; Transcription; Immediate early genes; Prenylation; FTase; Farnesyl transferase; GGTase; Geranylgeranyl transferase; HFPA; α-hydroxyfarnesylphosphonic acid; GGTI; Geranylgeranyl transferase inhibitor GGTI-286;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

EHT 1864, a small molecule inhibitor of Ras-related C3 botulinum toxin substrate 1 (Rac1), attenuates glucose-stimulated insulin secretion in pancreatic β-cells

Keywords: Arf6; ADP-ribosylation factor 6; Cdc42; Cell division control protein 42; ERK1/2; Extracellular signal-regulated kinases; GEF; Guanine nucleotide exchange factor; GDP; Guanosine diphosphate; GTP; Guanosine triphosphate; GGTI; Geranylgeranyl transferase in

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of RalA signaling pathway in treatment of non-small cell lung cancer

Keywords: Lung cancer; NSCLC; Ral; Signaling; Treatment; GGTI; Aurora kinase; CD133; CD44; Ras; RalBP1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation

Keywords: statins; isoprenoids; protein prenylation; synaptic plasticity; hippocampus; long-term potentiation; aCSF; artificial cerebral spinal fluid; AD; Alzheimer's disease; Akt; protein kinase B; fEPSPs; field excitatory postsynaptic potentials; FPP; farnesyl py

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Dual mode of HMG-CoA reductase inhibition on dendritic cell invasion

Keywords: ADMA; asymmetric dimethyl l-arginine; ATV; atorvastatin; CMFDA; 5-chloromethylfluorescein diacetate; FPP; farnesyl pyrophosphate; FTI; farnesyl-transferase inhibitor; GGP; geranylgeranyl pyrophosphate; GGTI; geranylgerany-transferase inhibitor; HMEC-1; im

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Modulation of host metabolism as a target of new antivirals

Keywords: HCV; hepatitis C virus; CH; chronic hepatitis; HCC; hepatocellular carcinoma; IFN; interferon; SVR; sustained virological response; PEG-IFN; pegylated-IFN; GBV-B; GB virus B; uPA-SCID; urokinase plasminogen activator-severe combined immunodeficiency; NS;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Inhibitory effects of mevastatin and a geranylgeranyl transferase I inhibitor (GGTI-2166) on mononuclear osteoclast formation induced by receptor activator of NFκB ligand (RANKL) or tumor necrosis factor-α (TNF-α)

Keywords: pOC; preosteoclast; RANKL; receptor activator of NFκB ligand; M-CSF; macrophage colony-stimulating factor; GGTI; geranylgeranyl transferase inhibitor; GGOH; geranylgeraniol; FTI; farnesyl transferase inhibitor; TRAP; tartrate-resistant acid phosphatase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Molecular targets for altering radiosensitivity: Lessons from Ras as a pre-clinical and clinical model

Keywords: PTI; prenyltransferase inhibitors; FTase; farnesyltransferase; GGTase; Geranylgeranyl transferase; FTI; FTase inhibitor; GGTI; GGTase inhibitor; MAPK; mitogen activated protein kinase; PI3K; phosphatidylinositol 3′-kinase; RTK; receptor tyrosine kinase;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

Statins potentiate the IFN-γ-induced upregulation of group IIA phospholipase A2 in human aortic smooth muscle cells and HepG2 hepatoma cells

Keywords: C/EBP-β; CAAT-enhancer-binding protein-β; cPLA2; cytosolic phospholipase A2; DRB; 5,6-Dichloro-1-β-d-ribofuranosylbenzimidazole; ELISA; enzyme linked immunosorbent assay; ERK; extracellular signal-regulated kinase; FCS; fetal calf serum; FPP; farnesyl

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه