Keywords: ABCB1; ATP-binding cassette sub-family B member 1; ABCG; ATP-binding cassette drug efflux transporters; ACD; autophagic cell death; AKT; alpha serine/threonine protein kinase; ALDH; aldehyde dehydrogenase; AMPK; AMP-activated protein kinase; AP; apurinic/
مقالات ISI (ترجمه نشده)
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Keywords: Metaplasia; GLI1; SHH; DAMPs; MDSCs; SPEM; ATPase; adenosine triphosphatase; DAMP; damage-associated molecular pattern; GLI; glioma-associated protein; Gr-MDSC; granulocytic myeloid-derived suppressor cell; HH; hedgehog; HHIP; hedgehog-interacting protein
Keywords: FAP; fibroadipogenic progenitors; PAX7; paired box 7; MRF; myogenic regulatory factor; Hh; Hedgehog; MyoD1; myogenic differentiation 1; Smo; Smoothened; Gli1; Gli family zinc finger 1; Ptch1; Patched 1; rRNA; ribosomal ribonucleic acid; CAGGS; CMV early e
Keywords: Glioblastoma; Treatment; Review; Pharmacology; Targeted therapy; Stem cell; AKT; protein kinase B; BBB; blood-brain barrier; BCNU; carmustin; CCNU; lomustin; c-MET; hepatocyte growth factor receptor; EGF(R); epidermal growth factor (receptor); EGFRvIII; e
Keywords: Stem cells; Niche; Tooth; Hair; Nail; Claw; Ectodermal derivatives; Gli1
Keywords: Primary cilia; Stroma; MDSCs; Gli1; Stomach;
Keywords: Hedgehog; Cyclopamine; Smoothened agonist (SAG); Purmorphamine (PMA); Gli1; Gli3; Dorsal aorta;
Keywords: Development; Gastric Epithelium; Signal Transduction; Tissue Regeneration; CCK-BR; cholecystokinin/gastrin-B receptor; ECL; enterochromaffin-like; GFP; green fluorescent protein; GKO; gastrin deficient; Gli1; glioma-associated oncogene homolog 1; Ihh; Ind
Keywords: Fungiform papilla; Papilla placode; Paracrine signaling; Stem cells; Taste cell progenitors; Ptch; Gli1; Gli2;
The expression of Shh, Ptch1, and Gli1 in the developing caudal spinal cord of fetal rats with ARMs
Keywords: Lumbosacral spinal cord; Shh; Ptch1; Gli1; Anorectal malformations;
Gli1-labeled adult mesenchymal stem/progenitor cells and hedgehog signaling contribute to endochondral heterotopic ossification
Keywords: Heterotopic ossification (HO); Adult mesenchymal stem/progenitor cells (MSC); Lineage tracing; Gli1; CD133; Hedgehog (Hh) signaling;
Emerging roles and mechanisms of FOXC2 in cancer
Keywords: FOXC2; Forkhead box protein C2; EMT; epithelial-mesenchymal transition; NSCLC; non-small cell lung cancer; EGFR; epidermal growth factor receptor; siRNA; small (or short) interfering RNA; MAPK; mitogen-activated protein kinase; PI3K; phosphatidylinosito
HDAC6 inhibition induces glioma stem cells differentiation and enhances cellular radiation sensitivity through the SHH/Gli1 signaling pathway
Keywords: Gloima stem cells; Radioresistance; HDAC6; Hedgehog pathway; Gli1;
NOX4-driven ROS formation regulates proliferation and apoptosis of gastric cancer cells through the GLI1 pathway
Keywords: NADPH oxidase 4; ROS; GLI1; Gastric cancer; Proliferation; Apoptosis;
Deubiquitylating enzymes as cancer stem cell therapeutics
Keywords: Protein-IPSC; protein-induced pluripotent stem cells; CSCs; cancer stem cells; DUBs; deubiquitylating enzymes; ESCs; embryonic stem cells; PTMs; post-translational modifications; AML; acute myelogenous leukemia; USP/UBP; ubiquitin-specific processing prot
Postnatal Sonic hedgehog (Shh) responsive cells give rise to oligodendrocyte lineage cells during myelination and in adulthood contribute to remyelination
Keywords: Cuprizone; Demyelination; Remyelination; Oligodendrogenesis; Oligodendrocyte progenitor; Sonic hedgehog; Myelination; Gli1; Oligodendrocyte lineage; Genetic fate labeling;
Identification of Variants in RET and IHH Pathway Members in a Large Family With History of Hirschsprung Disease
Keywords: ENS; Neural Development; Genetic Causes of HSCR; Family Study; bp; base pair; ENS; enteric nervous system; GDNF; glial cell-derived neurotrophic factor; GFP; green fluorescent protein; GLI1; GLI family zinc finger 1; GLI3; GLI family zinc finger 3; HEK;
Gli1 expression in cancer stem-like cells predicts poor prognosis in patients with lung squamous cell carcinoma
Keywords: Gli1; Cancer stem cell; Lung squamous cell carcinoma; Prognosis;
Identification and characterization of two novel PTCH1 splice variants
Keywords: Patched-1; Splice variants; Exon skipping; SHH; Sterol-sensing domain; GLI1;
Spop regulates Gli3 activity and Shh signaling in dorsoventral patterning of the mouse spinal cord
Keywords: Neural patterning; Ubiquitin ligase; Gli1; Gli2; Sufu; Spopl;
Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation
Keywords: HCC; Tumor Progression; Benign; SHH; bex7,8HCA; β-catenin mutated hepatocellular adenoma in exon 7 or 8; bex7,8IHCA; β-catenin mutated inflammatory hepatocellular adenoma in exon 7 or 8; bex3IHCA; β-catenin mutated inflammatory hepatocellular adenoma i
Identification of a DYRK1A-mediated phosphorylation site within the nuclear localization sequence of the hedgehog transcription factor GLI1
Keywords: Hedgehog; GLI1; DYRK1A; Phosphorylation; Nuclear localization; Mass spectrometry;
miR-873 suppresses H9C2 cardiomyocyte proliferation by targeting GLI1
Keywords: GLI1; glioma-associated oncogene 1; CHD; congenital heart disease; 3â²UTR; 3â²-untranslated region; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; CCK-8; Cell Counting Kit-8; PCNA; proliferating cell nuclear antigen; miR-873; GLI1; Cardiomyocyte; Cong
Gli1 is a potential cancer stem cell marker and predicts poor prognosis in ductal breast carcinoma
Keywords: Cancer stem cell; Ductal breast carcinoma; Gli1; Prognosis; Marker;
Pharmacological targeting of GLI1 inhibits proliferation, tumor emboli formation and in vivo tumor growth of inflammatory breast cancer cells
Keywords: Hedgehog; GLI1; GANT61; JK184; SUM149; IBC;
Aberrant expression of Sonic hedgehog signaling in Peutz-Jeghers syndrome
Keywords: CRA; colorectal adenoma; CRC; colorectal carcinoma; GLI1; GLI zinc finger protein 1; IRSs; immunoreactive scores; NC; normal colorectal mucosa; PTCH; Patched; PCR; polymerase chain reaction; PJS; Peutz-Jeghers syndrome; PJP; PJ polyps; SHH; Sonic hedgehog
Tea polyphenols epigallocatechin gallete and theaflavin restrict mouse liver carcinogenesis through modulation of self-renewal Wnt and hedgehog pathways
Keywords: HCC; hepatocellular carcinoma; NDEA; N-nitrosodiethyl amine; CD44; cluster of differentiation 44; sFRP1; secreted frizzled-related protein 1; APC; adenomatosis polyposis coli; Hh; hedgehog pathway; Gli1; glioma-associated oncogene homolog 1; SMO; smoothen
CAT3, a novel agent for medulloblastoma and glioblastoma treatment, inhibits tumor growth by disrupting the Hedgehog signaling pathway
Keywords: Medulloblastoma; Glioblastoma; Hedgehog; Smo; Gli1
Design, synthesis, and evaluation of hybrid vitamin D3 side chain analogues as hedgehog pathway inhibitors
Keywords: Vitamin D3; Hedgehog signaling; Gli1; Basal cell carcinoma; Medulloblastoma
p53 modulates the activity of the GLI1 oncogene through interactions with the shared coactivator TAF9
Keywords: TAF9; TATA binding protein associated factor 9; TAD1; acidic alpha helical transactivation domain; GLI1; p53; TAF9; Coactivator;
Epstein-Barr virus latent membrane protein 2A mediated activation of Sonic Hedgehog pathway induces HLA class Ia downregulation in gastric cancer cells
Keywords: Epstein Barr Virus; Gastric Cancer; LMP2A; Human Leukocyte Antigen; Sonic Hedgehog pathway; Gli1;
Stromal Indian Hedgehog Signaling Is Required for Intestinal Adenoma Formation in Mice
Keywords: COX2; Prostaglandin; Mouse Model; Colon Cancer; α-Sma Sma; α-Sma smooth muscle actin; Bmp; bone morphogenetic protein; BrdU; bromodeoxyuridine; Cyp1a1Cre; cytochrome p450-1a1Cre; Gli1; glioma-associated oncogene; Hhip; Hedgehog-interacting protein; Ihh;
Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing
Keywords: AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-
Wwox suppresses breast cancer cell growth through modulation of the hedgehog-GLI1 signaling pathway
Keywords: Breast cancer; Wwox; Gli1; Hedgehog;
Clinicopathological correlates of Gli1 expression in a population-based cohort of patients with newly diagnosed bladder cancer
Keywords: Gli1; Bladder neoplasm;
Research ArticleGli1 activation and protection against hepatic encephalopathy is suppressed by circulating transforming growth factor β1 in mice
Keywords: HE; hepatic encephalopathy; AOM; azoxymethane; TGFβ1; transforming growth factor beta 1; Gli1; glioma-associated oncogene homolog 1; TGFβR2; TGFβ receptor 2; Shh; sonic hedgehog; Ihh; indian hedgehog; HBC; (2-hydropropyl)-β-cyclodextrin; VM; vivo-morp
Aberrant activation of Sonic hedgehog signaling in chronic cholecystitis and gallbladder carcinoma
Keywords: Shh; Sonic hedgehog; Ptch; Patched; GBC; Gallbladder carcinoma; CC; Chronic cholecystitis; Sonic hedgehog pathway; Chronic cholecystitis; Gallbladder carcinoma; Ptch; Gli1;
Inhibition of hedgehog signaling by GANT58 induces apoptosis and shows synergistic antitumor activity with AKT inhibitor in acute T cell leukemia cells
Keywords: T-ALL; GLI1; GANT58; AKT inhibitor; Apoptosis; Hh; hedgehog; T-ALL; acute T cell leukemia; SMO; Smoothened; GLI1; GLI family zinc finger 1; SHH; Sonic hedgehog; DHH; Desert hedgehog; IHH; Indian hedgehog; PTCH1; Patched 1; PI3K; phosphatidylinositol 3-kin
The GLI1 splice variant TGLI1 promotes glioblastoma angiogenesis and growth
Keywords: GLI1; Hedgehog pathway; Transcriptional regulation; Angiogenesis; Cancer
Identification of novel non-coding RNA-based negative feedback regulating the expression of the oncogenic transcription factor GLI1
Keywords: Non-coding RNA; Gene expression; Transcription; Chromatin; GLI1; Cancer;
Fem1b promotes ubiquitylation and suppresses transcriptional activity of Gli1
Keywords: Fem1b; FEM-1; Gli1; TRA-1; Transcription; Ubiquitin;
New advances of DNA methylation in liver fibrosis, with special emphasis on the crosstalk between microRNAs and DNA methylation machinery
Keywords: miRNAs; small non-coding RNAs; HSC; hepatic stellate cell; ECM; extracellular matrix; α-SMA; α-smooth muscle actin; TGF-β; transforming growth factor-β; PDGF; platelet-derived growth factor; FGF; fibroblast growth factor; ICAM-1; intercellular adhesio
A feedback regulation between Kindlin-2 and GLI1 in prostate cancer cells
Keywords: Kindlin-2; GLI1; Hedgehog signaling; Feedback loop; Tumor cell viability;
Adenovirus vector-mediated Gli1 siRNA induces growth inhibition and apoptosis in human pancreatic cancer with Smo-dependent or Smo-independent Hh pathway activation in vitro and in vivo
Keywords: Hedgehog signaling; Gli1; siRNA; Adenovirus vector; Pancreatic cancer
Duration of Shh signaling contributes to mDA neuron diversity
Keywords: Sonic hedgehog; Gli1; Midbrain dopamine neurons; Substantia nigra pars compacta; Ventral tegmental area; Genetic inducible fate mapping
Loss of heterozygosity of the PTCH gene in ameloblastoma
Keywords: Ameloblastoma; Loss of heterozygosity; PTCH; GLI1; GLI2; Sonic Hedgehog pathway
Probing the structural requirements for vitamin D3 inhibition of the hedgehog signaling pathway
Keywords: Hedgehog pathway; Vitamin D3; Vitamin D2; Gli1; Cyp24A1; Vitamin D receptor
Evaluation of vitamin D3 A-ring analogues as Hedgehog pathway inhibitors
Keywords: Hedgehog pathway; Vitamin D3; Vitamin D receptor; Gli1; Cyp24A1
Different expression patterns of Gli1–3 in mouse embryonic maxillofacial development
Keywords: Gli1; Gli2; Gli3; Maxillofacial development; Expression pattern; Mouse