دانلود مقالات ISI درباره Glp-1 + ترجمه فارسی

A polyphenol-rich prebiotic in combination with a novel probiotic formulation alleviates markers of obesity and diabetes in Drosophila

Keywords: Probiotic; Synbiotic; Gut microbiota; Diabetes; Obesity; TOR; ACC; acetyl CoA-carboxylase; Akt; Protein kinase B; AMPK; 5′-adenosine monophosphate-activated protein kinase; Bi702255; Bifidobacteria longum spp. infantis NCIMB 702255; BMI; Body mass index

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Association of Native American ancestry and common variants in ACE, ADIPOR2, MTNR1B, GCK, TCF7L2 and FTO genes with glycemic traits in Colombian population

Keywords: ACE; angiotensin converting enzyme; MTNR1B; melatonin receptor 1B; GCK; glucokinase; TCF7L2; transcription factor 7 Like 2; FTO; alpha-ketoglutarate dependent dioxygenase; OR; odds ratio; IR; insulin resistance; T2D; type 2 diabetes; MS; metabolic syndrom

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Takeda G Protein-Coupled Receptor 5-Mechanistic Target of Rapamycin Complex 1 Signaling Contributes to the Increment of Glucagon-Like Peptide-1 Production after Roux-en-Y Gastric Bypass

Keywords: BAs; Bile acids; Cyp7a1; Cytochrome P450 family 7 subfamily A member 1; DCA; Deoxycholic acid; FXR; Farnesoid X receptor; GLP-1; Glucagon-like peptide-1; ip; Intraperitoneal; mTOR; mechanistic target of rapamycin; mTORC1; mechanistic target of rapamycin c

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Exendin-4 improves cardiovascular function and survival in flow-induced pulmonary hypertension

Keywords: pulmonary arteriopathy; glucagon-like peptide (Glp)-1 analogs; exendin-4; flow-induced pulmonary hypertension; interleukin-1β; α-SMA; α-smooth muscle actin; cAMP; cyclic adenosine monophosphate; c-GMP; cyclic guanosine monophosphate; eNOS; endothelial

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Spinal interleukin-10 produces antinociception in neuropathy through microglial β-endorphin expression, separated from antineuroinflammation

Keywords: GLP-1; glucagon-like peptide-1; IL-10; interleukin 10; TNF-α; tumor necrosis factor-α; IL-1β; interleukin-1β; IL-6; interleukin 6; p38 MAPK; p38 mitogen-activated protein kinase; NF-κB; nuclear factor κB; STAT3; signal transducer and activator of tr

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

Oxyntomodulin analogue increases energy expenditure via the glucagon receptor

Keywords: Oxyntomodulin; Energy expenditure; Receptor; Glucagon; GLP-1;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2018 سفارش ترجمه

Exendin-4 impairs the autophagic flux to induce apoptosis in pancreatic acinar AR42J cells by down-regulating LAMP-2

Keywords: Exendin-4; Pancreas; Impaired autophagy; Apoptosis; Ex-4; Exendin-4; GLP-1; glucagon-like peptide 1; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide; LC3B; light chain 3B; LAMP-2; lysosome associated membrance protein; CatB/L; cathepsin

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

Investigation of in vitro genotoxic effects of an anti-diabetic drug sitagliptin

Keywords: Sitagliptin; Antidiabetic drug; Human lymphocytes; Genotoxicity; T2DM; Type 2 diabetes mellitus; DPP-4; dipeptidyl peptidase-4; GLP-1; incretin hormones glucagon-like peptide-1; GIP; glucose-dependent insulinotropic polypeptide; CAs; chromosome aberration

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Glucagon-like receptor 1 agonists and DPP-4 inhibitors: Anti-diabetic drugs with anti-stroke potential

Keywords: Stroke; Diabetes; DPP-4 inhibitors; GLP-1; Neuroprotection; GLP-1R agonists;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

The GLP-1 response to glucose does not mediate beta and alpha cell dysfunction in Hispanics with abnormal glucose metabolism

Keywords: GLP-1; Insulinogenic index; Glucagon suppression index; Glucose tolerance; Hispanic;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Glucagon-like peptide-1 contributes to increases ABCA1 expression by downregulating miR-758 to regulate cholesterol homeostasis

Keywords: GLP-1; Cholesterol homeostasis; ABCA1; miR-758;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Intestinal CART is a regulator of GIP and GLP-1 secretion and expression

Keywords: CART; Cocaine- and amphetamine-regulated transcript; GIP; GLP-1; Enteroendocrine cells; Incretin hormones;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Pancreatic cancer-derived exosomes suppress the production of GIP and GLP-1 from STC-1 cells in vitro by down-regulating the PCSK1/3

Keywords: Pancreatic cancer-associated diabetes; Exosomes; GIP and GLP-1; PCSK1/3; Pancreatic juice; EV; Extracellular vesicle; GLP-1; Glucagon-like peptide-1; GIP; Gastric inhibitory polypeptide OR glucose-dependent insulinotropic polypeptide; PCSK1/3; Proprotein

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Coagonist of GLP-1 and glucagon decreases liver inflammation and atherosclerosis in dyslipidemic condition

Keywords: Coagonist; GLP-1; Glucagon; Atherosclerosis; Inflammation;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Novel GLP-1/GLP-2 co-agonists display marked effects on gut volume and improves glycemic control in mice

Keywords: GLP-1; GLP-2; Co-agonist; Diabetes; Obesity; Short bowel syndrome; Intestinal growth; Glucose homeostasis;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR

Keywords: Farnesoid X receptor; TGR5; Atherosclerosis; Obesity; NAFLD; α-Sma; alpha smooth muscle actin (α-Sma); BA; bile acid; BAT; brown adipose tissue; CEBPα; CCAAT/enhancer-binding protein α; Col1α1; collagen type 1 α1; DIO; diet-induced obesity; FXR; far

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Constitutive DPP4 activity, inflammation, and microvascular reactivity in subjects with excess body weight and without diabetes

Keywords: ADA; American Diabetes Association; AUC; area uder the curve; BMI; body mass index; CD26; cluster of differentiation 26; DPP4; dipeptidyl peptidase 4; EDTA; ethylenediamine tetraacetic acid; FPG; fasting plasma glucose; GIP; glucose-dependent insulinotrop

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

The prebiotic inulin improves substrate metabolism and promotes short-chain fatty acid production in overweight to obese men

Keywords: AMPK; adenosine monophosphate (AMP)-activated protein kinase; CHO; carbohydrate; DP; degree of polymerization; FFA; free fatty acid; GLP-1; glucagon-like peptide-1; GPR; G-coupled protein receptor; iAUC; incremental area under the curve; INU; inulin treat

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

The glucagon-like peptide-1 (GLP-1) analog liraglutide attenuates renal fibrosis

Keywords: CKD; chronic kidney disease; ESRD; end-stage renal disease; UUO; unilateral ureteral obstruction; EMT; epithelial-mesenchymal transition; ECM; extracellular matrix; GLP-1; glucagon-like peptide-1; GLP-1R; glucagon-like peptide-1 receptor; TGF-β1; transfo

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Exenatide exerts cognitive effects by modulating the BDNF-TrkB neurotrophic axis in adult mice

Keywords: GLP-1; GLP-1 receptor; Type 2 diabetes mellitus; Long-term potentiation; Cognitive enhancement;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Replacement of the C-terminal Trp-cage of exendin-4 with a fatty acid improves therapeutic utility

Keywords: DPP-IV; dipeptidyl peptidase IV; Ex-4; exendin-4; GLP-1; glucagon-like peptide-1; GLP-1R; glucagon-like peptide-1 receptor; IPGTT; intraperitoneal glucose tolerance test; NEP 24.11; neutral endopeptidase 24.11; nGLP-1R; N-terminal extracellular domain of

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Transhepatic bile acid kinetics in pigs and humans

Keywords: Bile acids; TGR5; Porcine; Postprandial; Portal concentrations; BAs; bile acids; ASBT; apical sodium-dependent bile acid transporter; OST; organic solute transporter; NTCP; taurocholate cotransporting polypeptide; OATP; organic anion transporting polypept

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Deactivation of the NLRP3 inflammasome in infiltrating macrophages by duodenal-jejunal bypass surgery mediates improvement of beta cell function in type 2 diabetes

Keywords: ASC; apoptosis-associated speck-like protein; AUC; area under the curve; CRP; circulating C-reactive protein; CD68; Cluster of Differentiation 68; DIO; diet-induced obesity; DMEM; Dulbecco's Modified Eagle Medium; DJB; duodenal-jejunal bypass; FBS; fetal

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

GLP-1 receptor agonists downregulate aberrant GnT-III expression in Alzheimer's disease models through the Akt/GSK-3β/β-catenin signaling

Keywords: AD; GnT-III; Bisecting N-glycans; GLP-1; Aβ;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Oleoyl-lysophosphatidylinositol enhances glucagon-like peptide-1 secretion from enteroendocrine L-cells through GPR119

Keywords: GLP-1; glucagon-like peptide-1; GPCR; G protein-coupled receptor; Oleoyl-LPI; Oleoyl-lysophosphatidylinositol; T2D; type 2 diabetes; Lysophosphatidylinositol (LPI); Glucagon-like peptide-1 (GLP-1); GPR119; GPR55; L-cells; Mixed colonic preparation;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Lixisenatide ameliorates cerebral ischemia-reperfusion injury via GLP-1 receptor dependent/independent pathways

Keywords: Stroke; Cerebral ischemia/reperfusion; GLP-1; Lixisenatide; Exendin(9−39);

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Human-based systems: Mechanistic NASH modelling just around the corner?

Keywords: Elafibranor (PubChem CID: 9864881); Obeticholic acid (PubChem CID: 447715); Pioglitazone (PubChem CID: 4829); Rosiglitazone (PubChem CID: 77999); Fenofibrate (PubChem CID: 3339); Serine (PubChem CID: 5951); ACC1; acetyl-coenzyme A carboxylase 1; AdipoR; a

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Safety and efficacy assessment of a GLP-1 mimetic: insulin glargine combination for treatment of feline diabetes mellitus

Keywords: feline; obesity; GLP-1; diabetes mellitus; incretin hormones;

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

IAPP in type II diabetes: Basic research on structure, molecular interactions, and disease mechanisms suggests potential intervention strategies

Keywords: 2DIR; two-dimensional infra-red spectroscopy; AFM; atomic force microscopy; AGE; advanced glycation end; CD; circular dichroism; CGRP; calcitonin gene-related peptides; DMSO; Dimethyl Sulfoxide; EGCG; epigallocatechin gallate; EPR; electron paramagnetic r

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Exploring the effects of DPP-4 inhibitors on the kidney from the bench to clinical trials

Keywords: Glucagon-like peptide-1 (PubChem CID: 16135499); Sitagliptin (PubChem CID: 4369359); Vildagliptin (PubChem CID: 6918537); Saxagliptin (PubChem CID: 11243969); Linagliptin (PubChem CID: 10096344); Alogliptin (PubChem CID: 11450633); AKI; acute kidney injur

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2018 سفارش ترجمه

Causes and solutions to “globesity”: The new fa(s)t alarming global epidemic

Keywords: Obesity; Chronic low-grade inflammation; Pharmacotherapy; Novel targets; Medicinal plants; Clinical studies; Contents; 5HT2CR; Serotonin receptors subtype 2C; ACC; Acetyl-CoA carboxylase (EC 6.4.1.2); ACTH; Adrenocorticotropic hormone; AgRP; Agouti-relate

دانلود رایگان متن کامل مقاله ISI 84 صفحه سال انتشار : 2018 سفارش ترجمه

Gastric bypass in the pig increases GIP levels and decreases active GLP-1 levels

Keywords: Gastric Bypass; GIP; GLP-1; Insulin; Bariatric surgery; Pig model;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Canagliflozin potentiates GLP-1 secretion and lowers the peak of GIP secretion in rats fed a high-fat high-sucrose diet

Keywords: Diet-induced obesity; Canagliflozin; Glucagon-like peptide-1; Glucose-dependent insulinotropic polypeptide; Sodium-glucose cotransporter 1(SGLT1); SGLT2 inhibitor; DPP-IV; dipeptidyl peptidase-IV; GLP-1; glucagon-like peptide-1; GIP; Glucose-dependent i

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Incretin effect of Urena lobata leaves extract on structure and function of rats islet β-cells

Keywords: Islet β-cells; GLP-1; Incretin; Insulin; U. lobata;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Lixisenatida en pacientes con diabetes tipo 2 y obesidad: más allá del control glucémico

Keywords: Diabetes tipo 2; Obesidad; Análogos de GLP-1; Lixisenatida; Control metabólico; Type 2 diabetes; Obesity; GLP-1; Lixisenatide; Metabolic control;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Glycyrrhizic acid increases glucagon like peptide-1 secretion via TGR5 activation in type 1-like diabetic rats

Keywords: Glycyrrhizic acid; GLP-1; TGR5; Triamterene; Sitagliptin;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Mini-reviewAppetite control by the tongue-gut axis and evaluation of the role of CD36/SR-B2

Keywords: Lipid sensor; Appetite control; CD36; SR-B2; Obesity; ApoAIV; apo-lipoprotein AIV; CCK; cholecystokinin; CM; chylomicron; DIO; diet-inducd obesity; GLP-1; glucagon-like peptide-1; LCFA; long-chain fatty acids; LPL; lipoprotein lipase; OEA; oleoylethanolam

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Feeding cycle-dependent circulating insulin fluctuation is not a dominant Zeitgeber for mouse peripheral clocks except in the liver: Differences between endogenous and exogenous insulin effects

Keywords: Circadian rhythm; Peripheral clock; Food entrainable oscillator; Insulin; Glucocorticoid; GLP-1; Mouse;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Changes in glycemic control and body weight after explantation of the duodenal-jejunal bypass liner

Keywords: BP; blood pressure; DJBL; duodenal-jejunal bypass liner; FPG; fasting plasma glucose; GLP-1; glucagon-like peptide-1; HbA1c; glycosylated hemoglobin A1c; T2DM; type 2 diabetes mellitus; TBWL; total body weight loss;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

A walnut-containing meal had similar effects on early satiety, CCK, and PYY, but attenuated the postprandial GLP-1 and insulin response compared to a nut-free control meal

Keywords: Walnuts; Insulin; Postprandial gastrointestinal peptides; Satiety; BMI; body mass index; CCK; cholecystokinin; GIP; glucose-dependent insulinotropic peptide; GLP-1; glucagon-like peptide-1; HDL-C; high-density lipoprotein cholesterol; MUFA; monounsaturate

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

A randomized cross-over study of the effects of macronutrient composition and meal frequency on GLP-1, ghrelin and energy expenditure in humans

Keywords: Ghrelin; GLP-1; Hunger; Indirect calorimetry; Low-carbohydrate; Meal frequency;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Glycaemic control and hypoglycaemia with insulin glargine 300 U/mL compared with glargine 100 U/mL in Japanese adults with type 2 diabetes using basal insulin plus oral anti-hyperglycaemic drugs (EDITION JP 2 randomised 12-month trial including 6-month ex

Keywords: Glycaemic control; Hypoglycaemia; Insulin glargine; Type 2 diabetes; AE; adverse event; ANCOVA; analysis of covariance; BL; baseline; BMI; body mass index; CI; confidence interval; FPG; fasting plasma glucose; Gla-100; glargine 100; Gla-300; glargine 300;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis and biological evaluation of an 111In-labeled exendin-4 derivative as a single-photon emission computed tomography probe for imaging pancreatic β-cells

Keywords: BCM; beta cell mass; DTBZ; dihydrotetrabenazine; DTPA; diethylenetriamine-pentaacetic acid; GFP; green fluorescent protein; GLP-1; glucagon-like peptide-1; MIP; mouse insulin I gene promotor; NOD; 1-(1,3-carboxypropyl)-1,4,7-triazacyclononane-4,7-diacetic

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

PEGylation, an approach for improving the pulmonary delivery of biopharmaceuticals

Keywords: AUC; area under plasma concentrations-time curve; BAL; bronchoalveolar lavage; DPI; dry powder inhaler; Fab'; antibody fragment; FITC; fluorescein isothiocyanate; FN; fibronectin; GLP-1; Glucagon-like peptide-1s; hGH; human growth hormone; IFN; interfer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

GLP-1 nanomedicine alleviates gut inflammation

Keywords: GLP-1 SSM; Diarrhea; IBD; Colitis; GLP-1; glucagon like peptide-1; SSM; sterically stabilized phospholipid micelles; DSS; dextran sodium sulfate; DRA; down regulated in adenoma; IBD; inflammatory bowel diseases; IL-1β; interleukin-1β;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Glucagon-like peptide-1 (GLP-1) increases in plasma and colon tissue prior to estrus and circulating levels change with increasing age in reproductively competent Wistar rats

Keywords: Appetite; Estrous cycle; Gut peptides; GLP-1; Ovarian cycle; PYY; Satiety;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Ablation of β,β-carotene-9′,10′-oxygenase 2 remodels the hypothalamic metabolome leading to metabolic disorders in mice

Keywords: ACC; acetyl-CoA carboxylase; AgRP; agouti-related protein; AKT; protein kinase B; AMPK; AMP-activated protein kinase; BCAA; branched-chain amino acid; BCO2; β,β-carotene-9′,10′-oxygenase2; CPT; carnitine palmitoyltransferase; GCS; glutamyl cysteine

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Partial jejunal diversion using an incisionless magnetic anastomosis system: 1-year interim results in patients with obesity and diabetes

Keywords: BMI; body mass index; GIP; gastric inhibitory peptide; GLP-1; glucagon-like peptide-1; HbA1c; glycated hemoglobin; IMAS; incisionless magnetic anastomosis system; NHANES; National Health and Nutrition Examination Survey; PJD; partial jejunal diversion; PY

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

A novel GLP-1/GIP dual agonist is more effective than liraglutide in reducing inflammation and enhancing GDNF release in the MPTP mouse model of Parkinson's disease

Keywords: Insulin; Growth factor; Incretins; Dopamine; Inflammation; Brain; GLP-1; GIP;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Glucagon-like peptide-2 promotes gallbladder refilling via a TGR5-independent, GLP-2R-dependent pathway

Keywords: Bile acids; Gallbladder; Enteroendocrine; Glucagon-like peptide; TGR5; GLP-1; GLP-2;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه