دانلود مقالات ISI درباره Gpcr Kinase + ترجمه فارسی

نوکلئوتید خارج سلولی باعث افزایش قدرت آگونیست در گیرنده هورمون 1 پاراتیروئید می شود

Extracellular nucleotides enhance agonist potency at the parathyroid hormone 1 receptor

Keywords: AMP-PNP; adenosine 5′- (β,γ-imido)triphosphate; BSA; bovine albumin; [Ca2+]i; cytosolic free Ca2+ concentration; cAMP; adenosine cyclic 3′,5′-monophosphate; CMP; cytidine 5′-monophosphate; CREB; cAMP response element binding protein; DMEM; Dulbe

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

قاچاق گیرنده متابوتروپ گلوتامات

Metabotropic glutamate receptor trafficking

Keywords: AC; adenylate cyclase; Actn4; α-Actinin-4; ARF6; ADP-ribosylation factor 6; ATD; amino terminal domain; CAIN; calcineurin inhibitor protein; CaM; calmodulin; CaMKII; Ca2+/calmodulin-dependent protein kinase II; Cbln1; cerebellin 1 precursor; CC; coiled-c

دانلود رایگان متن کامل مقاله ISI 83 صفحه سال انتشار : 2018 سفارش ترجمه

گیرنده های سطحی سلول های نوتروفیل و مسیرهای انتقال سیگنال داخل سلولی آنها

Neutrophil cell surface receptors and their intracellular signal transduction pathways

Keywords: Abl; Abelson leukemia proto-oncogene; ADAP; adhesion and degranulation promoting adapter protein (Fyb, SLAP-130); Asc; apoptosis-associated speck-like protein containing a CARD; BCR; B-cell receptor; C3G; Crk SH3 domain-binding guanine nucleotide exchange

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

β-Adrenergic Receptor Trafficking, Degradation, and Cell Surface Expression Are Altered in Dermal Fibroblasts from Hypertrophic Scars

Keywords: β-AR; adrenergic receptor; HSF; hypertrophic scar fibroblast; GRK; GPCR kinase; NSF; non-scar fibroblast; NF; normal fibroblast; PKA; protein kinase A;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Different phosphorylation patterns regulate α1D-adrenoceptor signaling and desensitization

Keywords: α1D-AR; α1D-adrenergic receptor; ERK; extracellular signal-regulated kinase; NA; noradrenaline; PMA; phorbol 12-myristate, 13-acetate; PKC; protein kinase C; GPCR; G protein-coupled receptor; GRK; GPCR kinase; IL3; intracellular loop 3; Ctail; carboxyl

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

GPCR Kinase (GRK)-2 Is a Key Negative Regulator of Itch: l-Glutamine Attenuates Itch via a Rapid Induction of GRK2 in an ERK-Dependent Way

Keywords: Ad-GRK2; adenovirus expressing GPCR kinase-2; CD; contact dermatitis; CQ; chloroquine; DNCB; dinitrochlorobenzene; Gln; l-glutamine; GRK; GPCR kinase; MKP-1; MAPK phosphatase-1; siRNA; small interfering RNA;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

The G protein-coupled receptors deorphanization landscape

Keywords: GPCRs; G protein-coupled receptors; GRK; GPCR kinase; IUPHAR; International Union of Basic and Clinical Pharmacology; BPS; British Pharmacological Society; CTR; Calcitonin receptor; CLR; CT Receptor-like; RAMP; Receptor Activity-Modifying Proteins; β2AR;

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

Spatial encryption of G protein-coupled receptor signaling in endosomes; Mechanisms and applications

Keywords: AKT (PKB); protein kinase B; AP2; adaptor protein 2; APPL1; adaptor protein containing PH domain, PTB domain, and Leucine zipper motif; ARRDC; arresting domain containing; Β1AR; B2AR, beta-adrenergic receptor 1 or 2; CCP; clathrin coated pit; CXCR4; chem

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

γ-Glutamyl cysteine and γ-glutamyl valine inhibit TNF-α signaling in intestinal epithelial cells and reduce inflammation in a mouse model of colitis via allosteric activation of the calcium-sensing receptor

Keywords: CaSR; calcium-sensing receptor; GPCR; G-protein-coupled receptor; IBD; inflammatory bowel disease; CD; Crohn's disease; UC; ulcerative colitis; γ-EC; γ-glutamyl cysteine; γ-EV; γ-glutamyl valine; GRK; GPCR kinase; TRAF; TNF-receptor-associated factor;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

New paradigms in GPCR drug discovery

Keywords: cAMP; 3′,5′-cyclic adenosine monophosphate; ADP; adenosine 5′- diphosphate; GPCR; G protein-coupled receptor; TM; transmembrane helix; ERK; extracellular signal-regulated kinase; T4L; T-4 lysozyme; BRIL; thermostabilized apocytochrome b562; StaRs; s

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Cardioprotective potential of annexin-A1 mimetics in myocardial infarction

Keywords: Ac2-26; Cardioprotection; Cardiomyopathy; Formyl peptide receptors; Inflammation; Ischemia-reperfusion; Aβ42; 42-amino acid beta-amyloid peptide; ABC; ATP-binding cassette; Ac2-26; N-terminal-derived annexin-A1 peptide (acetyl-AMVSEFLKQAWIENEEQEYVVQTVK

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

Mechanisms that underlie the internalization and extracellular signal regulated kinase 1/2 activation by PKR2 receptor

Keywords: AT1AR; angiotensin type 1A receptor; ConA; Concanavalin A; DN-GRK; dominant-negative G-protein-coupled receptor kinase 2; EGFP; enhanced green fluorescent protein; ERK; extracellular signal regulated kinase; GPCR; G-protein-coupled receptors; GRK; GPCR ki

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Homologous desensitization of human histamine H3 receptors expressed in CHO-K1 cells

Keywords: Histamine; H3 receptor; Desensitization; GRK; CHO-K1 cells; Neuromodulation; H3R; histamine H3 receptor; GPCR; G protein-coupled receptor; GRK; GPCR kinase; RAMH; R-α-methylhistamine;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

G protein-coupled receptor kinase 2 (GRK2) is a Rho-activated scaffold protein for the ERK MAP kinase cascade

Keywords: CNK1; connector enhancer of KSR-1; DGKθ; diacylglycerol kinase θ; EGF; epidermal growth factor; GIT; GRK-interacting protein; GPCR; G protein-coupled receptor; GRK; GPCR kinase; KSR-1; kinase suppressor of ras-1; MAPK; mitogen-activated protein kinase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Desensitization of human CRF2(a) receptor signaling governed by agonist potency and βarrestin2 recruitment

Keywords: CK1; casein kinase 1; CK2; casein kinase 2; CRF1 receptor; CRF receptor type 1; CRF2(a) receptor; CRF receptor type 2(a); K44A; dynamin dominant negative mutant; GPCR; G protein-coupled receptor; GRK; GPCR kinase; PKA; protein kinase A; PKC; protein kinas

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Suppression of adenylyl cyclase-mediated cAMP production by plasma membrane associated cytoskeletal protein 4.1G

Keywords: AGS; activator of G protein-signaling; cAMP; cyclic adenosine monophosphate; CTD; carboxy-terminal domain; DMEM; Dulbecco's modified Eagle's medium; EMEM; Eagle's minimum essential medium; Epac; exchange protein activated by cAMP; ERK; extracellular signa

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The cytoskeletal regulatory scaffold protein GIT2 modulates mesenchymal stem cell differentiation and osteoblastogenesis

Keywords: GPCR; G protein-coupled receptor; GRK; GPCR kinase; GIT; GRK-interacting protein; ARF-GAPs; ADP-ribosylation factor GTPase-activating proteins; GEF; guanine nucleotide exchange factor; MSC; mesenchymal stem cell; qCT; quantitative micro-computed tomograph

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

GRK5 deficiency decreases diet-induced obesity and adipogenesis

Keywords: ANOVA; analysis of variance; GPCR; G protein-coupled receptor; GRK; GPCR kinase; KO; knockout; SD; standard diet; HFD; high fat diet; WAT; white adipose tissue; MEF; mouse embryonic fibroblast; SVF; stromal vascular fraction cell; PPARγ; peroxisome pro

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

βγ subunits of Gi/o suppress EGF-induced ERK5 phosphorylation, whereas ERK1/2 phosphorylation is enhanced

Keywords: BDNF; brain-derived neurotrophic factor; CTX; cholera toxin; DMEM; Dulbecco's modified Eagle's medium; EGF; epidermal growth factor; EPAC; exchange protein activated by cAMP; ERK; extracellular signal-regulated kinase; GPCR; G-protein-coupled receptor; G3

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Toll-like receptors differentially regulate GPCR kinases and arrestins in primary macrophages

Keywords: Arrestin-2; Arrestin-3; Beta-arrestin; TLR; GPCR; TLR4; GRK2; GRK5; GRK6; GPCR kinase; TLR3; TLR2; TLR7

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Activation of tyrosine kinase of EGFR induces Gβγ-dependent GRK-EGFR complex formation

Keywords: EGF; Epidermal growth factor; EGFR; EGF receptor; GPCR; G protein-coupled receptor; GRK; GPCR kinase; GRK2 DelN; GRK2 N-terminal deletion mutant; HA; hemagglutinin; HEK; human embryonic kidney; SDS-PAGE; polyacrylamide gel electrophoresis in the presenc

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

Agonist-induced up-regulation of human somatostatin receptor type 1 is regulated by β-arrestin-1 and requires an essential serine residue in the receptor C-tail

Keywords: AC; adenylyl cyclase; CaM; calcium calmodulin; CHO-KI; Chinese hamster ovary cell line; FBS; fetal bovine serum; GPCR; G protein-coupled receptor; GRK; GPCR kinase; hSSTR; human somatostatin receptor; MAPK; mitogen activated protein kinase; PKA; protein k

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه