Keywords: Niacin; Macrophage polarization; GPR109A; Parkinson's disease;
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: heat shock; in vitro culture; GPR109A; prostaglandin E2; heat shock proteins;
Keywords: ABCG1; ATP-binding cassette sub-family G member 1; β-OHB; beta-hydroxybutyrate; cAMP; cyclic adenosine monophosphate; COX; cyclooxygenase; EC50; half maximal effective concentration; FAE; fumaric acid esters; Gi; G-inhibitory; GPR; G-protein coupled rece
Keywords: GPR109A; HCAR2; HM74a; Inflammation; Niacin; Niacinamide;
Butyrate ameliorated-NLRC3 protects the intestinal barrier in a GPR43-dependent manner
Keywords: T2DM; type 2 diabetes; PRRs; pattern recognition receptors; TLRs; toll-like receptors; NOD; nucleotide-binding oligomerization domain; NLRs; nucleotide-binding oligomerization domain (NOD)-like receptors; MAMPs; microbe-associated molecular patterns; NLRP
Overexpressing cell systems are a competitive option to primary adipocytes when predicting in vivo potency of dual GPR81/GPR109A agonists
Keywords: GPR81; GPR109A; In vitro-in vivo correlation; Non-esterified fatty acids (NEFA); PKPD modeling; Nonlinear mixed effects (NLME) modeling; Drug discovery;
Sodium Butyrate Inhibits Inflammation and Maintains Epithelium Barrier Integrity in a TNBS-induced Inflammatory Bowel Disease Mice Model
Keywords: GPR109A; SB; TNBS; IBD; Inflammation; Epithelium barrier; Cldn1; claudin-1; DSS; dextran sulfate sodium; FITC; fluorescein isothiocyanate; GPR109A; G Protein Coupled Receptor 109A; IBD; inflammatory bowel disease; LPS; lipopolysaccharide; MUC2; mucin-2; P
Discovery of coumarin-dihydroquinazolinone analogs as niacin receptor 1 agonist with in-vivo anti-obesity efficacy
Keywords: Niacin; Niacin receptor 1; GPR109a; Pharmacophore hybridization; Coumarin-dihydroquinazolinone; Homology modeling;
Associate editor: B. TeicherBenefits of short-chain fatty acids and their receptors in inflammation and carcinogenesis
Keywords: GPR41; G protein-coupled receptor 41; GPR43; G protein-coupled receptor 43; GPR109A; G protein-coupled receptor 109A; HDAC; Histone deacetylases; DSS; dextran sulfate sodium; AOM; azoxymethane; APC; adenomatous polyposis; DC; dendritic cell; Treg; T regul
Niacin receptor GPR109A inhibits insulin secretion and is down-regulated in type 2 diabetic islet beta-cells
Keywords: NA; nicotinic acid; BHB; β-hydroxybutyrate; FFAs; free fatty acids; cAMP; cyclic adenosine monophosphate; GSIS; glucose stimulated insulin secretion; PTX; pertussis toxin; IBMX; 3-isobutyl-1-methylxanthine; DAB; 3,3â²-diaminobenzidine; DAPI; 4',6-diam
Differential tissue and ligand-dependent signaling of GPR109A receptor: Implications for anti-atherosclerotic therapeutic potential
Keywords: Biased signaling; Niacin; GPR109A; Atherosclerosis; ABCA1; Macrophage;
Agonists of the G protein-coupled receptor 109A-mediated pathway promote antilipolysis by reducing serine residue 563 phosphorylation of hormone-sensitive lipase in bovine adipose tissue explants
Keywords: lipolysis; adipose tissue; hormone-sensitive lipase; GPR109A;
Relationship of Lipoproteins to Cardiovascular Events : The AIM-HIGH Trial (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes)
Keywords: cardiovascular events; clinical trial; GPR109A; lipoproteins; niacinCV, cardiovascular; ER, extended-release; HDL-C, high-density lipoprotein cholesterol; HR, hazard ratio; GPR109A, G-protein–coupled receptor 109A; LDL-C, low-density lipoprotein cholester
Structure–activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A)
Keywords: Nicotinic acid; GPR109A; Fumaric acid; Cinnamic acid; G protein-coupled receptor
Discovery of pyrazolyl propionyl cyclohexenamide derivatives as full agonists for the high affinity niacin receptor GPR109A
Keywords: Agonist; GPR109A; Niacin; Niacin receptor; Cyclohexenamides;
Pyrido pyrimidinones as selective agonists of the high affinity niacin receptor GPR109A: Optimization of in vitro activity
Keywords: Flushing; GPR109A; GPR109B; GPCR; Lead identification; Lipolysis; Niacin; Pyrido pyrimidinone
Anthranilic acid replacements in a niacin receptor agonist
Keywords: Niacin receptor; HDL; Atherosclerosis; Coronary disease; GPR109A; Anthranilic acid;
GPR109a agonists. Part 1: 5-Alkyl and 5-aryl-pyrazole–tetrazoles as agonists of the human orphan G-protein coupled receptor GPR109a
Keywords: Niacin; GPR109a; Atherosclerosis
The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist
Keywords: DMF, dimethylfumarate; FE, fumarate esters; HDL, high density lipoprotein; MEF, monoethylfumarate; MMF, monomethylfumarate; NA, nicotinic acidBG-12; Fumaderm; Fumarate ester; GPR109A; Keratinocyte; Monomethylfumarate; Multiple sclerosis; Niacin; Nicotinic
Discovery of pyrazolopyrimidines as the first class of allosteric agonists for the high affinity nicotinic acid receptor GPR109A
Keywords: Pyrazolopyrimidines; Allosteric agonists; Nicotinic acid receptor; GPR109A
Suppression of blood lipid concentrations by volatile Maillard reaction products
Keywords: Diabetes mellitus; GPR109A; Maillard reaction products; Non-esterified fatty acids; Foods;
3-Nitro-4-amino benzoic acids and 6-amino nicotinic acids are highly selective agonists of GPR109b
Keywords: Niacin; GPR109a; GPR109b; HM74; HM74A; PUMA-G; HDL; Lipolysis
Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109a
Keywords: Niacin; GPR109a; GPR109b; GPCRs; Lipolysis; Free fatty acids; Selectfluor; Cutaneous flushing; Pyrazole carboxylic acids; HM74; HM74a; PUMA-G
Agonist lead identification for the high affinity niacin receptor GPR109a
Keywords: GPR109a; HM74a; Niacin receptor; Free fatty acids; Lead identification
Comparison of rat and dog models of vasodilatation and lipolysis for the calculation of a therapeutic index for GPR109A agonists
Keywords: Acipimox; Dog; GPR109A; Lipolysis; Methods; Nicotinic acid; Rat; Therapeutic index; Vasodilatation