دانلود مقالات ISI درباره Grk + ترجمه فارسی

GRK-6 mediates FSH action synergistically enhanced by estrogen and the oocyte in rat granulosa cells

Keywords: DES; diethylstilbestrol; FSHR; follicle-stimulating hormone receptor; GRK; G protein-coupled receptor kinase; IBMX; 3-isobutyl-1-methylxanthine; P450arom; P450 aromatase; siRNA; small interfering RNA; StAR; steroidogenic acute regulatory protein; Estrogen

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Differential regulation of chemotaxis: Role of Gβγ in chemokine receptor-induced cell migration

Keywords: CHO; Chinese hamster ovary; CCL3; Chemokine ligand 3; CCR5; Chemokine receptor 5; DMEM; Dulbecco's modified Eagle's medium; EDTA; Ethylenediaminetetraacetic acid; ERK; Extracellular signal-regulated kinases; FCS; Foetal calf serum; GPCR; G protein coupled

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

G protein-coupled receptor kinase 2 (GRK2) is a Rho-activated scaffold protein for the ERK MAP kinase cascade

Keywords: CNK1; connector enhancer of KSR-1; DGKθ; diacylglycerol kinase θ; EGF; epidermal growth factor; GIT; GRK-interacting protein; GPCR; G protein-coupled receptor; GRK; GPCR kinase; KSR-1; kinase suppressor of ras-1; MAPK; mitogen-activated protein kinase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Epithelial G protein-coupled receptor kinases regulate the initial inflammatory response during mycobacterial infection

Keywords: GPCR; G protein-coupled receptors; GRK; G protein-coupled receptor kinase; LAM; lipoarabinomannan; PI-3K; phosphoinositide 3-kinases; ERK; extracellular signal-regulated kinase; Akt; serine/threonine protein kinase; COPD; chronic obstructive pulmonary dis

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

The three α1-adrenoceptor subtypes show different spatio-temporal mechanisms of internalization and ERK1/2 phosphorylation

Keywords: α1-AR; α1 adrenoceptor; β2-AR; β2 adrenoceptor; AT1AR; angiotensin receptor type 1A; Bmax; maximum number of binding sites; BSA; bovine serum albumin; ConA; concanavalin A; DMSO; dimethyl sulfoxide; EGFR; epidermal growth factor receptor; GAPDH; glyce

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Desensitization of human CRF2(a) receptor signaling governed by agonist potency and βarrestin2 recruitment

Keywords: CK1; casein kinase 1; CK2; casein kinase 2; CRF1 receptor; CRF receptor type 1; CRF2(a) receptor; CRF receptor type 2(a); K44A; dynamin dominant negative mutant; GPCR; G protein-coupled receptor; GRK; GPCR kinase; PKA; protein kinase A; PKC; protein kinas

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

E-type prostanoid receptor 4 (EP4) in disease and therapy

Keywords: AMPK; AMP-activated protein kinase; cAMP; cyclic adenylyl monophosphate; CFTR; cystic fibrosis transmembrane conductance regulator; ClC; chloride channel; COX; cyclooxygenase; CREB; cAMP-response element-binding protein; DP; D-type prostanoid receptor; DS

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2013 سفارش ترجمه

Dysregulation of cannabinoid CB1 receptor and associated signaling networks in brains of cocaine addicts and cocaine-treated rodents

Keywords: Akt; protein kinase B; ANCOVA; analyses of covariance; CB; cannabinoid; CB2xP; mice overexpressing CB2 receptors; F1; cytosolic fraction; F2; membrane fraction; F3; nuclear fraction; F4; cytoskeletal fraction; FAAH; fatty acid amide hydrolase; GRK; G prot

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2013 سفارش ترجمه

G-protein coupled receptor kinase (GRK)-5 regulates proliferation of glioblastoma-derived stem cells

Keywords: GBM; Glioblastoma derived stem cells; GRK; Proliferation

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Suppression of adenylyl cyclase-mediated cAMP production by plasma membrane associated cytoskeletal protein 4.1G

Keywords: AGS; activator of G protein-signaling; cAMP; cyclic adenosine monophosphate; CTD; carboxy-terminal domain; DMEM; Dulbecco's modified Eagle's medium; EMEM; Eagle's minimum essential medium; Epac; exchange protein activated by cAMP; ERK; extracellular signa

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Endogenous opiates and behavior: 2012

Keywords: Ach; acetylcholine; ACTH; adrenocorticotrophic hormone; ANG; angiotensin; ATP; adenosine triphosphate; BAM22; bovine adrenal medulla 22; BDNF; brain-derived neurotrophic factor; BEND; beta-endorphin; BFNA; beta-funaltrexamine; BNST; bed nucleus of the str

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2013 سفارش ترجمه

CCL3 induced migration occurs independently of intracellular calcium release

Keywords: CHO; Chinese hamster ovary; DMEM; Dulbecco's modified eagle's medium; EDTA; ethylenediaminetetraacetic acid; FCS; foetal calf serum; GPCR; G protein coupled receptor; GRK; G-protein coupled receptor kinase; PBS; phosphate buffered saline; PKC; protein

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

GRK5 deficiency decreases diet-induced obesity and adipogenesis

Keywords: ANOVA; analysis of variance; GPCR; G protein-coupled receptor; GRK; GPCR kinase; KO; knockout; SD; standard diet; HFD; high fat diet; WAT; white adipose tissue; MEF; mouse embryonic fibroblast; SVF; stromal vascular fraction cell; PPARγ; peroxisome pro

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The cytoskeletal regulatory scaffold protein GIT2 modulates mesenchymal stem cell differentiation and osteoblastogenesis

Keywords: GPCR; G protein-coupled receptor; GRK; GPCR kinase; GIT; GRK-interacting protein; ARF-GAPs; ADP-ribosylation factor GTPase-activating proteins; GEF; guanine nucleotide exchange factor; MSC; mesenchymal stem cell; qCT; quantitative micro-computed tomograph

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Regulation of the methylation status of G protein-coupled receptor kinase 1 (rhodopsin kinase)

Keywords: GRK; G protein‐coupled receptor kinase; ICME; isoprenylcysteine carboxyl methyltesterase; ICMT; isoprenylcysteine carboxyl methyltransferase; SAM; S-adenosyl-L-methionine; CAAX moif; Calcium signalling; Light adaptation; Carboxymethylation; Neuronal cal

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

S-nitrosylation-regulated GPCR signaling

Keywords: GPCR; GRK; Arrestin; Dynamin; S-nitrosylation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

AAV6-βARKct gene delivery mediated by molecular cardiac surgery with recirculating delivery (MCARD) in sheep results in robust gene expression and increased adrenergic reserve

Keywords: 2; 17; 29; βAR; β-adrenergic receptor; βARK; β-adrenergic receptor kinase; βARKct; carboxyl terminus of β-adrenergic receptor kinase; cAMP; cyclic adenosine monophosphate; CPB; cardiopulmonary bypass; ESPVR; end-systolic pressure-volume relationsh

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

cAMP: Novel concepts in compartmentalised signalling

Keywords: cAMP; cyclic adenosine 3′,5′-monophosphate; GPCR; G protein-coupled receptor; EC coupling; excitation-contraction coupling; FRET; Förster/fluorescence resonance energy transfer; CFP; cyan fluorescent protein; YFP; yellow fluorescent protein; AKAR;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

[35S]GTPγS binding and opioid tolerance and efficacy in mouse spinal cord

Keywords: [35S]GTPγS; guanosine 5′-O-(3-[35S] thio)triphosphate; DAMGO; D-Ala2,N-MePhe4,Gly-ol5enkephalin; CCAM; clocinnamox; GRK; G-protein-coupled receptor kinase; cAMP; 3′-5′-cyclic adenosine monophosphate; PAG; periaqueductal gray; AAALAC; Association fo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Reversal of inhibition of putative dopaminergic neurons of the ventral tegmental area: Interaction of GABAB and D2 receptors

Keywords: aCSF; artificial cerebrospinal fluid; CGP35348; (3-aminopropyl)(diethoxymethyl)phosphinic acid; DA; dopamine; DAergic; dopaminergic; DIR; dopamine inhibition reversal; GIRKs; G-protein-linked inwardly rectifying potassium channels; Gö6976; 5,6,7,13-tetra

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Leptin-induced downregulation of the rat hippocampal somatostatinergic system may potentiate its anorexigenic effects

Keywords: AC; adenylyl cyclase; CREB; cyclic AMP response element binding protein; Gi; GTP-binding inhibitory protein; GRK; G-protein-coupled receptor kinase; IFNγ; interferon-γ; IL; interleukin; SDS; sodium dodecyl sulfate; SOCS3; suppressor of cytokine signalin

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Cannabinoid receptor trafficking in peripheral cells is dynamically regulated by a binary biochemical switch

Keywords: ATTC; American type culture collection; AMAM; anilino-monoindolylmaleimide; CB1; cannabinoid receptor type-1; CB2; cannabinoid receptor type-2; CDx; cluster of differentiation x; CHO; Chinese hamster ovary-K1; CM; cell membrane; CNR1; CB1 receptor gene; C

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2012 سفارش ترجمه

The expression change of β-arrestins in fibroblast-like synoviocytes from rats with collagen-induced arthritis and the effect of total glucosides of paeony

Keywords: TGP; total glucosides of paeony; RA; rheumatoid arthritis; CIA; collagen-induced arthritis; GRK; G-protein-coupled receptor kinases; FLS; fibroblast-like synoviocytes; GTW; glucosides of tripterygium wilfordii; GPCRs; G protein-coupled receptors; AA; adju

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Thromboxane-Induced Contractile Response of Human Coronary Arterioles Is Diminished After Cardioplegic Arrest

Keywords: 31; CABG; coronary artery bypass grafting; CaM PK; calmodulin phosphorylase kinase; CPB; cardiopulmonary bypass; CP/Rep; cardioplegia followed by reperfusion; DAPI; 4',6-diamidino-2-phenylindole; GRK; G protein-coupled receptor kinase; GSK; glycogen synth

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Age-related β-adrenergic receptor-mediated vasorelaxation is changed by altering G protein receptor kinase 2 expression

Keywords: AKAP; A kinase anchoring protein; adeno; Adenovirus; β-AR; Beta-adrenergic receptor; BCA; Bicinchoninic acid; ED50; Effective dose 50% response; EV; Empty adenovirus vector; ECL; Enhanced chemiluminescence; FSK; Forskolin; GRK; G protein receptor kinase;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Angiotensin II causes endothelial dysfunction via the GRK2/Akt/eNOS pathway in aortas from a murine type 2 diabetic model

Keywords: α-AR; α-adrenergi receptor; ACh; acetylcholine; AngII; angiotensin II; DM; diabetic mice; eNOS; endothelial oxide synthase; GPCR; G-protein-coupled receptor; GRK; G-protein-coupled receptor kinase; IGTT; intravenous glucose tolerance test; IRS-1; insuli

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Role of ßarrestins in bradykinin B2 receptor-mediated signalling

Keywords: GPCRs; G protein-coupled receptors; ERK1/2; extracellular signal-regulated protein kinases; BK; bradykinin; B2R; bradykinin type 2 receptor; B2R-4A; B2R where 4 serine and threonine were mutated to alanines (Thr342/345, Ser346/348); GRK; G protein recepto

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Dual Mode of glucagon receptor internalization: Role of PKCα, GRKs and β-arrestins

Keywords: Glucagon receptor; PKCα; GRK; β-Arrestin

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Non-canonical functions of RGS proteins

Keywords: AC; adenylyl cyclase; CHO; Chinese hamster ovary; CNK1; connector enhancer of KSR1; CREB; cAMP-response element binding protein; DH; dbl-homology; DMAP1; Dnmt1-associated protein 1; EGF; epidermal growth factor; eIF; eukaryotic initiation factor; ERK; ext

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Gαq allosterically activates and relieves autoinhibition of p63RhoGEF

Keywords: AF; Alexa Fluor 532; Dbs; Dbl's big sister; DH; Dbl homology; FCPIA; Flow cytometry protein interaction assay; FP; Fluorescence polarization; GFP; Green fluorescent protein; GRK; G protein-coupled receptor kinase; GPCR; G protein-coupled receptor; MFI; Me

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Dexamethasone enhances the norepinephrine-induced ERK/MAPK intracellular pathway possibly via dysregulation of the α2-adrenergic receptor: Implications for antidepressant drug mechanism of action

Keywords: 5-HT; serotonin; AP-1; activator protein 1; AR; adrenergic receptor; BDNF; brain derived neurotrophic factor; DEX; dexamethasone; FCS; fetal calf serum; GC; glucocorticoid; GPCR; G-protein-coupled receptor; GR; glucocorticoid receptor; GRK; G-protein rece

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

From the cell to the clinic: A comparative review of the partial D2/D3 receptor agonist and α2-adrenoceptor antagonist, piribedil, in the treatment of Parkinson's disease

Keywords: Ropinirole; Pramipexole; Pergolide; Antiparkinson; α2-Adrenoceptor; D2 receptor; D3 receptor; ACh; acetylcholine; Akt; atypical kinase; AR; adrenoceptor; BDNF; brain derived neurotrophic factor; COMT; catechol-Ortho-methyltransferase; DA; dopamine; ERK;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2010 سفارش ترجمه

Physiological and pharmacological implications of beta-arrestin regulation

Keywords: G protein coupled receptors; Seven transmembrane spanning receptors; GRK; Beta-arrestin; Functional selectivity; Knockout mouse models; Drug discovery; Receptor regulation; PhysiologyΔ9-THC, Δ9-tetrahydrocannabinol; DOI, 2,5-dimethoxy-4-iodoamphetamine; C

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Synaptic Scaffolding Molecule Binds to and Regulates Vasoactive Intestinal Polypeptide Type-1 Receptor in Epithelial Cells

Keywords: CFTR; cystic fibrosis transmembrane conductance regulator; GPCR; G-protein-coupled receptor; GRK; G-protein-coupled receptor kinase; Isc; short circuit current; MAGI-2; membrane-associated guanylate kinase inverted-2; MAGUK; membrane-associated guanylate

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2009 سفارش ترجمه

Inhibition of protein kinase Cα improves myocardial β-adrenergic receptor signaling and ventricular function in a model of myocardial preservation

Keywords: 17; 29; 31; ACT; specific activation; ATP; Adenosine triphosphate; βAR; β-Adrenergic receptor; CK; creatine kinase; GRK; G protein-coupled receptor kinase; INH; specific inhibition; PKC; protein kinase C; UW; University of Wisconsin;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

βγ subunits of Gi/o suppress EGF-induced ERK5 phosphorylation, whereas ERK1/2 phosphorylation is enhanced

Keywords: BDNF; brain-derived neurotrophic factor; CTX; cholera toxin; DMEM; Dulbecco's modified Eagle's medium; EGF; epidermal growth factor; EPAC; exchange protein activated by cAMP; ERK; extracellular signal-regulated kinase; GPCR; G-protein-coupled receptor; G3

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Desensitization of herpesvirus-encoded G protein-coupled receptors

Keywords: GPCR; Cytomegalovirus; KSHV; HCMV; MCMV; US28; M33; ORF74; GRK; Arrestin; Desensitization

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Role of the carboxyl terminal di-leucine in phosphorylation and internalization of C5a receptor

Keywords: C5aR; C5a receptor; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase; ERK1/2; extracellular signal-regulated kinase 1/2; CHO; Chinese hamster ovary; EndoH; endoglycosidase H; AR; adrenergic receptor; Chemoattractant receptor; Endoc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Different kinases desensitize the human δ-opioid receptor (hDOP-R) in the neuroblastoma cell line SK-N-BE upon peptidic and alkaloid agonists

Keywords: Opioid receptor; Desensitization; Phosphorylation; GRK; Second-messenger kinase

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Membrane interactions of G proteins and other related proteins

Keywords: G proteins; Ras proteins; GRK; Protein–lipid interaction; Posttranslational lipid modifications; Membrane lipid structure; Cell signaling

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Recycling of the human prostacyclin receptor is regulated through a direct interaction with Rab11a GTPase

Keywords: C-tail; carboxyl-terminal tail; FBS; foetal bovine serum; GFP; green fluorescent protein; GPCR; G protein-coupled receptor; GRK; GPCR receptor kinase; HA; hemagglutinin; HEK; human embryonic kidney; hIP; human IP; IC; intracellular; IP; prostacyclin recep

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2008 سفارش ترجمه

Agonist-dependent internalization and trafficking of the human prostacyclin receptor: A direct role for Rab5a GTPase

Keywords: C-tail; carboxyl-terminal tail; CCV; clathrin coated vesicles; FBS; foetal bovine serum; GFP; green fluorescent protein; GPCR; G protein-coupled receptor; GRK; GPCR receptor kinase; HA; hemagglutinin; HEK; human embryonic kidney; hIP; human IP; IP; prosta

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2008 سفارش ترجمه

Receptor regulation in neuroendocrine–immune communication: Current knowledge and future perspectives

Keywords: G-protein coupled receptors; GRK; Immune modulation; Glucocorticoid receptors; Adrenergic receptors

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Cerebellar cortical-layer-specific control of neuronal migration by pituitary adenylate cyclase-activating polypeptide

Keywords: cerebellar development; granule cell; neuronal cell migration; cAMP; rate of cell movement; desensitization; E; embryonic day; EGL; external granular layer; Erk; extracellular signal-regulated; GalR1; galanin receptor 1; GRK; G-protein-coupled receptor ki

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2007 سفارش ترجمه

Relationship between the G protein signaling and homologous desensitization of G protein-coupled receptors

Keywords: Signaling; Desensitization; GPCR; GRK; β-Arrestin; Dopamine D3 receptor; β2-Adrenergic receptor; Ste2p

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Characterization of the desensitization properties of five dopamine receptor subtypes and alternatively spliced variants of dopamine D2 and D4 receptors

Keywords: Signaling; Desensitization; GPCR; GRK; β-Arrestin; Dopamine receptor; SH3-binding domain

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Phosphorylation: A molecular switch in opioid tolerance

Keywords: Phosphorylation; Protein kinase; Phosphatase; PKC; CaMKII; PKA; PKG; GRK; CREB; NO; cAMP; cGMP; Calmodulin; Calcium; NMDA

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Homologous desensitization of signalling by the beta (β) isoform of the human thromboxane A2 receptor

Keywords: C-tail; carboxyl-terminal tail; [Ca2+]i; intracellular calcium; FBS; foetal bovine serum; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase; HA; hemagglutinin; HEK; human embryonic kidney; IP; prostacyclin receptor; IP3; inositol 1,

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2006 سفارش ترجمه

Activation of tyrosine kinase of EGFR induces Gβγ-dependent GRK-EGFR complex formation

Keywords: EGF; Epidermal growth factor; EGFR; EGF receptor; GPCR; G protein-coupled receptor; GRK; GPCR kinase; GRK2 DelN; GRK2 N-terminal deletion mutant; HA; hemagglutinin; HEK; human embryonic kidney; SDS-PAGE; polyacrylamide gel electrophoresis in the presenc

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

Role of the β-adrenergic receptor kinase in myocardial dysfunction after brain death

Keywords: AC; adenylate cyclase; ANOVA; analysis of variance; ATP; adenosine triphosphate; BD; brain death; cAMP; cyclic adenosine monophosphate; GRK; G protein-coupled receptor kinases; HF; heart failure; LV; left ventricular; PRSW; preload recruitable stroke wo

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه