دانلود مقالات ISI درباره Grp78 + ترجمه فارسی

STAT3 contributes to lysosomal-mediated cell death in a novel derivative of riccardin D-treated breast cancer cells in association with TFEB

Keywords: STAT3; signal transducers and activators of transcription 3; RD-N; Riccardin D-N; CTSB; cathepsin B; LMP; lysosomal membrane permeabilization; LAMP1; lysosome associated membrane protein 1; LM-PCD; lysosomal-mediated programme of cell death; AO; acridine

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Andrographolide, a diterpene lactone from Andrographis paniculata and its therapeutic promises in cancer

Keywords: Andrographolide; Andrographis paniculata; Diterpene lactone; Anticancer; Chemotherapy; Bioactive lactone; ACS; American Chemical Society; AKT; activated protein kinase; Andro; Andrographolide derivative or conjugate; AP-1; activator protein-1; Cdk; Cyclin

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

Protein tyrosine phosphatase 1B regulates endothelial endoplasmic reticulum stress; role in endothelial dysfunction

Keywords: Shear stress; Nitric oxide; Protein kinase RNA-like endoplasmic reticulum kinase; Mesenteric resistance artery; Ach; Acetylcholine; ATF6; Activated Transcription Factor 6; BAX; Bcl-2-Associated X Protein; BCL2; B-Cell Lymphoma 2; CHOP; C/EBP Homologous

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

GRP78 Promotes Hepatocellular Carcinoma proliferation by increasing FAT10 expression through the NF-κB pathway

Keywords: GRP78; FAT10; Hepatocellular carcinoma; NF-κB pathway; Tumor proliferation; Regulatory mechanism;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

The unknown face of IRE1α - Beyond ER stress

Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; IRE1; inositol requiring kinase enzyme 1; XBP1; x-box binding protein 1; bZIP; basic leucine zipper domain; HAC1; histone acetyl transferase 1; ATF; activating transcription factor; RIDD; regulate

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Steroids from Helleborus caucasicus reduce cancer cell viability inducing apoptosis and GRP78 down-regulation

Keywords: Helleborus caucasicus; Ecdysteroids; Bufadienolides; Cell viability; Apoptosis; GRP78; DMSO; dimethylsulfoxide; MTT; 3-(4,5 dimethylthiazol-2-yl)-2,5diphenyltetrazolium; BrdU; bromodeoxyuridine; DEVD; Asp-Glu-Val-Asp; pNA; p-nitroanilide; VP16; Etoposide;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Involvement of glucose-regulated protein 78 and spliced X-box binding protein 1 in the protective effect of gliclazide in diabetic nephropathy

Keywords: Diabetic nephropathy; ER stress; GRP78; XBP1; Gliclazide;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Vitamin D attenuates pressure overload-induced cardiac remodeling and dysfunction in mice

Keywords: ANP; atrial natriuretic peptide; ATF-6; activating transcription factor 6; BNP; brain natriuretic peptide; BW; body weight; CHOP; C/EBP homologous protein; DHE; dihydroethidine; EF; ejection fraction; ER; endoplasmic reticulum; FS; fractional shortening;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

FKBP8 protects the heart from hemodynamic stress by preventing the accumulation of misfolded proteins and endoplasmic reticulum-associated apoptosis in mice

Keywords: αMHC-Cre; α-myosin heavy chain promoter-driven Cre recombinase; BCL2L13; Bcl-2-like protein 13; CCCP; mitochondrial uncoupler carbonyl cyanide m-chlorophenylhydrazone; ER; endoplasmic reticulum; FKBP8; FK506-binding protein 8; GRP78; glucose-regulated p

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

ER stress and cancer: The FOXO forkhead transcription factor link

Keywords: Endoplasmic reticulum; ER stress; Cancer; FOXO; Forkhead transcription factors; Unfolded protein response; AKT; Protein Kinase B; AKT1; Protein Kinase B Alpha; AMPK; AMP-activated protein kinase; ASK1; Apoptosis Signal Regulated Kinase 1; ATF4; Activating

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Antiproliferative effect of p-Coumaric acid targets UPR activation by downregulating Grp78 in colon cancer

Keywords: Cancer chemoprevention; Colon cancer; p-Coumaric acid; Grp78 (78 kDa glucose regulated protein); ER stress; Apoptosis; Grp78; 78 kDa glucose regulated protein; DMH; dimethylhydrazine; PERK; protein kinase R-like ER kinase; IRE1α; inositol-requiring e

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Novel oxindole derivatives prevent oxidative stress-induced cell death in mouse hippocampal HT22 cells

Keywords: ER stress; Ferroptosis; Oxidative stress; Oxindole; Oxytosis; Rasagiline; ATF6; activated transcription factor 6; ARE; antioxidant response element; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic reticulum; Grp78; 78-kDa glucose-regulated prote

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Endoplasmic reticulum stress-dependent ROS production mediates synovial myofibroblastic differentiation in the immobilization-induced rat knee joint contracture model

Keywords: ATF6; activating transcription factor 6; ATF6α; activating transcription factor 6 alpha; CHOP; C/EBP homology protein; DMSO; dimethylsulphoxide; DCHF-DA; 2′,7′-dichlorofluorescein diacetate; DPI; diphenyleneiodonium; ER; endoplasmic reticulum; GAPDH;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Impact of microRNAs on ischemic stroke: From pre- to post-disease

Keywords: AAV; adeno-associated virus; ABCA1; ATP-binding cassette transporter 1; AGO; argonaute; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionate; AT1R; angiotensin II type 1 receptor; AQPs; aquaporins; BBB; blood-brain barrier; Bcl-6; B-cell lymphoma-6;

دانلود رایگان متن کامل مقاله ISI 76 صفحه سال انتشار : 2018 سفارش ترجمه

Autophagy in ischemic stroke

Keywords: 3-MA; 3-methyladenine; Aβ; amyloid β; AIF; apoptosis-inducing factor; Akt; protein kinase B; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; Atg; autophagy-related genes; ATP; adenosine 5′-triphosphate; BBB; blood-brain ba

دانلود رایگان متن کامل مقاله ISI 78 صفحه سال انتشار : 2018 سفارش ترجمه

ATP-independent inhibition of amyloid beta fibrillation by the endoplasmic reticulum resident molecular chaperone GRP78

Keywords: Amyloid beta; GRP78; Molecular chaperone; Protein-protein interaction;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client

Keywords: Unfolded protein response; GRP78; Protein folding; Calorimetry;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

TSA protects H9c2 cells against thapsigargin-induced apoptosis related to endoplasmic reticulum stress-mediated mitochondrial injury

Keywords: GRP78; Endoplasmic reticulum stress; Mitochondrion; TSA;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Ctenopharyngodon idella PERK (EIF2AK3) decreases cell viability by phosphorylating eIF2α under ER stress

Keywords: PERK; GRP78; eIF2α; ER stress; Fish;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Research reportInhibition of the mitochondrial calcium uniporter inhibits Aβ-induced apoptosis by reducing reactive oxygen species-mediated endoplasmic reticulum stress in cultured microglia

Keywords: Aβ; amyloid-beta; Ca2+; calcium; MCU; mitochondrial calcium uniporter; ROS; reactive oxygen species; ER; endoplasmic reticulum; GRP78; glucose-regulated protein 78; CHOP; C/-EBP homologous protein; AD; Alzheimer's disease; TNF-α; tumor necrosis factor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Sesame oil lignans inhibit hepatic endoplasmic reticulum stress and apoptosis in high-fat diet-fed mice

Keywords: CHOP; C/EBP homologous protein; CPT-1; carnitine palmitoyl transferase 1; ER; endoplasmic reticulum; FAS; fatty acid synthase; GC; gas chromatography; GRP78; 78-kDa glucose-regulated protein; HFD; high-fat diet; HMGCR; 3-hydroxy-3-methylglutaryl-CoA reduc

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleSensitivity towards the GRP78 inhibitor KP1339/IT-139 is characterized by apoptosis induction via caspase 8 upon disruption of ER homeostasis

Keywords: Sodium trans-[tetrachlorobis(1H-indazole)ruthenate(III)]; Ruthenium; Extrinsic pathway of programmed cell death; GRP78; Caspase 8; 4-PBA; 4-phenylbutyric acid; CHOP; C/EBP-homologous protein; CI; combination index; CFTR; cystic fibrosis transmembrane cond

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Proteomic analysis of liver tissue from rainbow trout (Oncorhynchus mykiss) under high rearing density after administration of dietary vitamin E and selenium nanoparticles

Keywords: ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate transaminase; ATPsyn-d; ATP synthase subunit d; CAT; catalase; Enol; alpha-2 enolase; FAA; fumarylacetoacetase; FBPA; fructose-bisphosphate aldolase; FDH; 10-formyltetrahydrofolate d

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

PPARβ/δ activation protects against corticosterone-induced ER stress in astrocytes by inhibiting the CpG hypermethylation of microRNA-181a

Keywords: PPARβ/δ; ER stress; Methylation; miR181a; GRP78;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition

Keywords: GALNT6; polypeptide N-acetylgalactosaminyltransferase 6; VVA; Vicia villosa agglutinin; GalNAc; N-acetylgalactosamine; GRP78; glucose-regulated protein 78; ER; endoplasmic reticulum;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

AR-12 suppresses dengue virus replication by down-regulation of PI3K/AKT and GRP78

Keywords: AR-12; Dengue; PI3K/AKT; GRP78; Antivirus; DENV; dengue virus; PI3K; phosphoinositide 3-kinase; GRP78; glucose-regulated protein 78; HSP; heat-shock protein;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Short-term molecular and physiological responses to heat stress in neritic copepods Acartia tonsa and Eurytemora affinis

Keywords: Acclimation; Biomarker; GRP78; Heat-shock; HSP70; HSP90; Oxygen consumption; Stress proteins;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

HPW-RX40 prevents human platelet activation by attenuating cell surface protein disulfide isomerases

Keywords: CHOP; CCAAT-enhancer-binding protein homologous protein; Di-E-GSSG; dieosin glutathione disulfide; DiOC6(3); 3,3′-dihexyloxacarbocyanine iodide; DTT; dithiothreitol; GSSG; oxidized glutathione; ER; endoplasmic reticulum; EGSH; eosin-coupled glutathione;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

GRP78 enabled micelle-based glioma targeted drug delivery

Keywords: GRP78; Stable VAP peptides; Polymeric micelle; Glioma; Targeted drug delivery;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Characterization of cadmium chloride-induced BiP accumulation in Xenopus laevis A6 kidney epithelial cells

Keywords: GRP78; Unfolded protein response; Aggregated protein; Aggresomes; Buthionine sulfoximine; Heat shock; HSP70; HO-1;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

A positive feedback loop between GRP78 and VPS34 is critical for GRP78-mediated autophagy in cancer cells

Keywords: GRP78; Autophagy; VPS34; MicroRNA-143; Positive feedback;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleGRP78 inhibition enhances ATF4-induced cell death by the deubiquitination and stabilization of CHOP in human osteosarcoma

Keywords: Osteosarcoma; ATF4; GRP78; CHOP; Ubiquitination; ATF4; activating transcription factor 4; BTZ; bortezomib; CFDA SE; carboxyfluorescein diacetate succinimidyl ester; CHOP; CCAAT/enhancer-binding protein (C/EBP) homologous protein; CHX; cycloheximide; DDIT3

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

T-cadherin promotes autophagy and survival in vascular smooth muscle cells through MEK1/2/Erk1/2 axis activation

Keywords: AMPK; 5′ adenosine monophosphate-activated protein kinase; BSA; bovine serum albumin; CQ; chloroquine; EC; endothelial cell; eIF2α; eukaryotic translation initiation factor 2α; ER; endoplasmic reticulum; Erk1/2; extracellular signal-regulated kinase;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

A mechanism underlies fish GRP78 protection against Pb2+ toxicity

Keywords: Pb2+; Cytotoxicity; GRP78; ER stress; Teleost;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

HSPA5 Gene encoding Hsp70 chaperone BiP in the endoplasmic reticulum

Keywords: aa; amino acid; ATF6; activating transcription factor 6; BIK; BCL2-interacting killer; BiP; binding immunoglobulin protein; CD86; cluster of differentiation 86; CHOP; CCAAT-enhancer-binding protein homologous protein; Derlin-1; degradation in ER protein 1

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

miR-199a-5p and miR-495 target GRP78 within UPR pathway of lung cancer

Keywords: NSCLC; Non-small cell lung cancer; UPR; Unfolded Protein Response; FFPE; Formalin-Fixed Paraffin-Embedded; miRNAs; microRNAs; ER; endoplasmic reticulum; ICD-O; International classification of diseases for oncology; no-RT; no-reverse transcription; REST; r

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

ER stress disturbs SR/ER-mitochondria Ca2 + transfer: Implications in Duchenne muscular dystrophy

Keywords: ATF6; activating transcription factor 6; ATP; Adenosine triphosphate; CTL; Control; Ddit3; DNA damage inducible transcript 3; DMD; Duchenne Muscular Dystrophy; EDL; Extensor Digitorum Longus; EIF2α; eukaryotic translation initiation factor 2A; FBS; fetal

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Cell surface GRP78 facilitates hepatoma cells proliferation and migration by activating IGF-IR

Keywords: Hepatoma; GRP78; IGF-IR; Signaling;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Intraventricular administration of Tenebrio molitor larvae extract regulates food intake and body weight in mice with high-fat diet-induced obesity

Keywords: Appetite; Diet-induced obesity; Hypothalamus; Neuropeptide; Tenebrio molitor larvae; AgRP; agouti-related peptide; ATF4; activating transcription factor 4; CHOP; c/EBP-homologous protein; eIF2α; α subunit of eukaryotic translation initiation factor 2; E

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Metabolic syndrome enhances endoplasmic reticulum, oxidative stress and leukocyte-endothelium interactions in PCOS

Keywords: PCOS; polycystic ovary syndrome; IR; insulin resistance; ER; endoplasmic reticulum; HOMA; homeostatic model assessment; ROS; reactive oxygen species; ICAM-1; intercellular adhesion molecule 1; VCAM-1; vascular cell adhesion molecule 1; IL-6; interleukin 6

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Rifampicin-induced injury in HepG2 cells is alleviated by TUDCA via increasing bile acid transporters expression and enhancing the Nrf2-mediated adaptive response

Keywords: RFP; rifampicin; TUDCA; tauroursodeoxycholic acid; Nrf2; nuclear factor erythroid 2-related factor; DILI; drug-induced liver injury; ALF; acute liver failure; TB; tuberculosis; INH; isoniazid; GSH; glutathione; BAs; bile acids; ER; endoplasmic reticulum;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Tetramethylpyrazine suppresses angiotensin II-induced soluble epoxide hydrolase expression in coronary endothelium via anti-ER stress mechanism

Keywords: AUDA; 12-[[(tricyclo[3.3.1.13,7]dec-1ylamino)carbonyl]amino]dodecanoic acid; 4-PBA; 4-phenylbutyric acid; GRP78; 78-kDa glucose-regulated protein; ATF6; Activating transcription factor 6; Ang-II; Angiotensin-II; CYP; Cytochrome P450; ER stress; Endoplasmi

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Questiomycin A stimulates sorafenib-induced cell death via suppression of glucose-regulated protein 78

Keywords: Hepatocellular carcinoma; Sorafenib; GRP78;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

17beta-hydroxysteroid dehydrogenase type 5 is negatively correlated to apoptosis inhibitor GRP78 and tumor-secreted protein PGK1, and modulates breast cancer cell viability and proliferation

Keywords: 17β-HSD5; 17beta-hydroxystroid dehydrogenase type 5; 2-D gel; two-dimensional gel; E2; estradiol; ER; estrogen receptor; ER+; ER-positive; GRP78; 78 kDa glucose-regulated protein; HSPA5/GRP78; heat shock 70 kDa protein 5/78 kDa glucose-regulated prote

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Effects of vitamin D and resveratrol on metabolic associated markers in liver and adipose tissue from SAMP8 mice

Keywords: AD; Alzheimer's disease; AMPK; AMP-activated protein kinase; APP; amyloid precursor protein; AUC; area under the curve; ER; endoplasmic reticulum; EPI; epididymal; FFAs; free fatty acids; GRP78; 78 kDa glucose-regulated protein; GTT; glucose tolerance te

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

The regulation of cellular apoptosis by the ROS-triggered PERK/EIF2α/chop pathway plays a vital role in bisphenol A-induced male reproductive toxicity

Keywords: AIF; apoptosis-inducing factor; ATF6; activating transcription factor 6; BPA; bisphenol A; CHOP; CCAAT/enhancer-binding protein-homologous protein; Cyt-c; cytochrome complex; EdU; 5-ethynyl-2′-deoxyuridine; EIF2α; eukaryotic initiation factor 2 α; ER;

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

GRP78 plays an integral role in tumor cell inflammation-related migration induced by M2 macrophages

Keywords: TAM; tumor-associated macrophage; M1-T; the M1 macrophages derived from THP-1; M2-T; the M2 macrophages derived from THP-1; M1-H; the M1 macrophages derived from hPBMC; M2-H; the M2 macrophages derived from hPBMC; MCM; macrophages conditioned medium; M1-M

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Cystathionine beta-synthase deficiency alters hepatic phospholipid and choline metabolism: Post-translational repression of phosphatidylethanolamine N-methyltransferase is a consequence rather than a cause of liver injury in homocystinuria

Keywords: APAP; acetaminophen; ALT; alanine aminotransferase; BSO; buthionine sulfoximine; CCl4; carbon tetrachloride; HCU; classical homocystinuria; CCT; CTP:choline phosphate cytidylyltransferase; CBS; cystathionine beta-synthase; CGL; cystathionine gamma-lyase;

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2017 سفارش ترجمه

Targeting chaperones, heat shock factor-1, and unfolded protein response: Promising therapeutic approaches for neurodegenerative disorders

Keywords: 17-AAG; 17-(allylamino)-17-demethoxygeldanamycin (tanespimycin); 17-DMAG; 17- dimethylaminoethylamino-17-demethoxygeldanamycin (alvespimycin); AAV; adeno-associated virus; Aβ; amyloid-β; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP;

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2017 سفارش ترجمه

Dehydroascorbic acid-induced endoplasmic reticulum stress and leptin resistance in neuronal cells

Keywords: Dehydroascorbic acid (DHAA); Leptin; Unfolded protein response (UPR); Leptin resistance; Endoplasmic reticulum (ER) stress; DHAA; dehydroascorbic acid; AA; ascorbic acid; UPR; unfolded protein response; ATF6; activating transcription factor 6; CHOP; C/EBP

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه