دانلود مقالات ISI درباره Grp78 + ترجمه فارسی

Synergistic enhancement of cancer therapy using a combination of heat shock protein targeted HPMA copolymer-drug conjugates and gold nanorod induced hyperthermia

Keywords: HPMA copolymers; Hyperthermia; GRP78; Gold nanorods; Targeted drug delivery; Prostate cancer;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Mitochondrial superoxide mediates mitochondrial and endoplasmic reticulum dysfunctions in TRAIL-induced apoptosis in Jurkat cells

Keywords: DCFH-DA; 2′,7′-Dichlorodihydrofluorescein diacetate; DHE; dihydroethidine; ΔΨm; mitochondrial membrane potential; ER; endoplasmic reticulum; FCCP; carbonyl cyanide p-trifluoromethoxyphenylhydrazone; FITC; fluorescein isothiocyanate; GRP78; glucose-r

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Bidirectional regulation of NF-κB by reactive oxygen species: A role of unfolded protein response

Keywords: NF-κB; nuclear factor-κB; UV; ultraviolet; IκB; inhibitor of NF-κB; IKK; IκB kinase; NEMO; NF-κB essential modulator; TNFR; tumor necrosis factor receptor; IL-1R; interleukin-1 receptor; NIK; NF-κB inducing kinase; LPS; lipopolysaccharide; PKD; pro

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Proteomic characterization of larval and adult developmental stages in Echinococcus granulosus reveals novel insight into host-parasite interactions

Keywords: 2D-LC-MS; two dimensional LC-MS; AE; alveolar echinococcosis; Ag5; antigen 5; AGC; automatic gain control; BCA; bicinchoninic acid assay; CE; cystic echinococcosis; CHD; cystic hydatid disease; DB; database; DLC; dynein light chain; EgFABP1; E. granul

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2013 سفارش ترجمه

Pro-apoptotic signaling induced by photo-oxidative ER stress is amplified by Noxa, not Bim

Keywords: CHOP; C/EBP homologous protein; eIF2a; eukaryotic initiation factor-2a; ER; endoplasmic reticulum; GRP78; glucose regulated protein 78; Hyp-PDT; hypericin-based photodynamic therapy; ICD; immunogenic cell death; MEF; murine embryonic fibroblast; PERK; pan

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Cell-surface GRP78 facilitates colorectal cancer cell migration and invasion

Keywords: GRP78; Colorectal cancer; Migration; Invasion; uPA

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

A peptide derived from phage display library exhibits anti-tumor activity by targeting GRP78 in gastric cancer multidrug resistance cells

Keywords: Gastric cancer; MDR; GRP78; Peptide; Phage display peptide library

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Overexpression of GRP78 in complete hydatidiform moles

Keywords: GRP78; Hydatidiform moles; Immunohistochemistry; p53; MMP-2; qPCR

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics

Keywords: ASK1; apoptosis signal-regulating kinase 1; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; BAX; Bcl2 associated X protein; BAK; BCL2-antagonist/killer; CHOP; C/EBP-homologous protein; eIF2α; eukaryotic initiation factor

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Dermokine-β impairs ERK signaling through direct binding to GRP78

Keywords: ERK; extracellular-signal-regulated kinase; MEK; mitogen-activated protein kinase; SCC; squamous cell carcinoma; GRP78; glucose-regulated protein 78; Dermokine-β; Keratinocyte; Differentiation; ERK1/2; GRP78;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

GRP78 counteracts cell death and protein aggregation caused by mutant huntingtin proteins

Keywords: Huntington's disease; Endoplasmic reticulum stress; GRP78; Caspase12;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Exposure to lipid-rich follicular fluid is associated with endoplasmic reticulum stress and impaired oocyte maturation in cumulus-oocyte complexes

Keywords: ATF4; ATF6; endoplasmic reticulum stress; free fatty acids; GRP78; lipotoxicity; obesity; triglyceride

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

IGFBP-3 sensitizes antiestrogen-resistant breast cancer cells through interaction with GRP78

Keywords: GRP78; IGFBP-3; Caspase-7; Apoptosis; Breast cancer; Drug-resistanceIGF, insulin-like growth factor; IGFBP, IGF binding protein; Ad, adenovirus; EV, empty vector; MOI, multiplicity of infection; ER, endoplasmic reticulum

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Decreased expression of endoplasmic reticulum chaperone GRP78 in liver of diabetic mice

Keywords: GRP78; Diabetes; Insulin resistance; ER stress; Proteomic analysis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Endoplasmic reticulum chaperone GRP78 suppresses the aggregation of proteins containing expanded polyglutamine tract

Keywords: Polyglutamine diseases; GRP78; Protein aggregation; ER stress

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Expression of autophagy and ER stress-related proteins in primary salivary adenoid cystic carcinoma

Keywords: Adenoid cystic carcinoma; LC3; Beclin 1; GRP78

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Anti-KDEL-coated nanoparticles: A promising tumor targeting approach for ovarian cancer?

Keywords: Nanoparticle; Targeting; Ovarian cancer; GRP78; GRP94; DiO; dioctadecyloxacarbo-cyanine perchlorate; EDAC; 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimidide; ER; endoplasmic reticulum; GRP; glucose-regulated protein; HER; herceptin; mAb; monoclonal antibod

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

3-Bromo-7-nitroindazole attenuates brain ischemic injury in diabetic stroke via inhibition of endoplasmic reticulum stress pathway involving CHOP

Keywords: Focal cerebral ischemia; 3-Bromo-7-nitroindazole; Type 2 diabetes; ER stress; GRP78; CHOP; DNA fragmentation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Redox signaling loops in the unfolded protein response

Keywords: AGR2; anterior gradient 2; ARE; antioxidant responsive element; ATF4; activating transcription factor-4; ATF6; activating transcription factor-6; ASK1; apoptosis signal-regulating kinase-1; BI-1; BAX inhibitor-1; BiP; immunoglobulin heavy chain-binding pr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

GRP78 induced by estrogen plays a role in the chemosensitivity of endometrial cancer

Keywords: Endometrial cancer; GRP78; Estrogen; Molecular chaperone

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Anti-cancer properties of glucosamine-hydrochloride in YD-8 human oral cancer cells: Induction of the caspase-dependent apoptosis and down-regulation of HIF-1α

Keywords: Apaf-1; apoptotic protease activating factor-1; Bcl-2; B cell lymphoma-2; Bcl-xL; B cell lymphoma-extra large; DCFH-DA; 2′,7′-dichlorofluorescein-diacetate; ECL; enzyme-linked chemiluminescence; FBS; fetal bovine serum; GAPDH; glyceraldehyde-3-phospha

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Targeted Antivascular Therapy with the Apolipoprotein(a) Kringle V, rhLK8, Inhibits the Growth and Metastasis of Human Prostate Cancer in an Orthotopic Nude Mouse Model

Keywords: Apo(a); apolipoprotein(a); GRP78; glucose-regulated protein 78; IHC; immunohistochemistry; i.p.; intraperitoneal; MVD; mean vessel density; PCNA; proliferating cell nuclear antigen; PK5; plasminogen kringle 5; TUNEL; deoxynucleotidyl transferase-mediated

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

ER stress is associated with reduced ABCA-1 protein levels in macrophages treated with advanced glycated albumin - Reversal by a chemical chaperone

Keywords: ABCA-1; ATP binding cassette transporter class A type I; ABCG-1; ATPbinding cassette transporter class G type I; AGE; advanced glycation end products; AGE-alb; advanced glycated albumin; Apo A-I; apolipoprotein A-I; ATF6; activating transcription factor 6

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Minimally modified low-density lipoprotein induces macrophage endoplasmic reticulum stress via toll-like receptor 4

Keywords: AS; atherosclerosis; LDL; low-density lipoprotein; mm-LDL; minimally modified LDL; ERS; endoplasmic reticulum stress; ox-LDL; oxidative modified LDL; GRP78; glucose-regulated proteins 78; IRE1; inositol-requiring enzyme 1; ATF6; activating transcription f

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Participation of endoplasmic reticulum stress in the pathogenesis of spontaneous glomerulosclerosis-Role of intra-renal angiotensin system

Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; GS; glomerulosclerosis; AT-1; angiotensin II receptor type1; ARB; angiotensin receptor-1 blockade; GRP94; glucose-regulated protein 94; GRP78; glucose-regulated protein 78, GRP78 also known as BiP

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Guided delivery of polymer therapeutics using plasmonic photothermal therapy

Keywords: Polymer therapeutics; Gold nanorod; Hyperthermia; Prostate cancer; GRP78; Photothermal therapy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

The endoplasmic reticulum stress response is involved in apoptosis induced by aloe-emodin in HK-2 cells

Keywords: AE; Aloe-emodin; ASK1; apoptosis signal-regulating kinase 1; ATF; activating transcription factor; CHAC1; cation transport regulator-like protein 1; CHOP; CAAT/enhancer-binding protein-homologous protein; DR5; death receptor 5; eIF2α; eukaryotic initiati

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Basic ScienceAtf6α-null mice are glucose intolerant due to pancreatic β-cell failure on a high-fat diet but partially resistant to diet-induced insulin resistance

Keywords: ATF6α; activating transcription factor 6α; BW; body weight; cDNA; complementary DNA; DO; diet-induced obese; eIF2α; eukaryotic initiation factor 2; ER; endoplasmic reticulum; G6Pase; glucose-6-phosphatase; GRP78; 78 kDa glucose-regulated protein; HFD;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Dentin sialophosphoprotein and dentin matrix protein-1: Two highly phosphorylated proteins in mineralized tissues

Keywords: DSPP; dentin sialophosphoprotein; DSP; dentin sialoprotein; DPP; dentin phosphoprotein (alternative names: Dentin phosphophoryn or phosphophoryn); DMP-1; dentin matrix protein-1; SIBLINGs; small integrin-binding ligand N-linked glycoproteins; FGF-23; fibr

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Involvement of the molecular chaperone Hspa5 in copper homeostasis in astrocytes

Keywords: Copper; Hspa5; Grp78; Atp7a; Astrocyte; Metallothionein

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

DHA induces apoptosis by altering the expression and cellular location of GRP78 in colon cancer cell lines

Keywords: DHA; Colon cancer cell; Apoptosis; GRP78; ERK1/2;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Endoplasmic reticulum stress-mediated inhibition of NSMase2 elevates plasma membrane cholesterol and attenuates NO production in endothelial cells

Keywords: NO; nitric oxide; ER; endoplasmic reticulum; BAEC; bovine aortic endothelial cells; eNOS; endothelial nitric oxide synthase; NSMase or NSM; neutral sphingomyelinase; SREBP-2; sterol-responsive element-binding protein; Tm; tunicamycin; Pm; palmitate; RNAi;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Bax inhibitor-1 regulates the expression of P450 2E1 through enhanced lysosome activity

Keywords: BI-1; BAX inhibitor-1; ROS; reactive oxygen species; ER; endoplasmic reticulum; UPR; unfolded protein response; GRP78; glucose response protein 78; CHOP; C/EBP homologous protein; eIF-2α; eukaryotic initiation factor; JNK; c-Jun N-terminal kinase; BAX in

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

ReviewER chaperone-metal interactions: Links to protein folding disorders

Keywords: Chaperones; Endoplasmic reticulum; Lead; Copper; Neurotoxicity; GRP78; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Glucose oxidase induces insulin resistance via influencing multiple targets in vitro and in vivo: The central role of oxidative stress

Keywords: Glucose oxidase; Insulin resistance; ROS; Oxidative stress; Akt; protein kinase B; AUC; area under the curve; CAT; catalase; ER; endoplasmic reticulum; ERK; extracellular signal-regulated kinases; FBG; fasting blood glucose; FOXO1α; Forkhead Box O 1α; G

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Differential redox proteomics allows identification of proteins reversibly oxidized at cysteine residues in endothelial cells in response to acute hypoxia

Keywords: CAM; carboxyamidomethylation; FDR; false discovery rate; Grp78; 78 kDa glucose-regulated protein; HIF; hypoxia-inducible factor; Hsc70; Heat shock cognate 71 kDa protein; Hsp; heat shock protein; HUVEC; human umbilical vein endothelial cells; LDH; lacta

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Effects of nitric oxide synthase-3 overexpression on post-translational modifications and cell survival in HepG2 cells

Keywords: 4TO; cells transfected with the empty plasmid 4TO; 4TO-NOS; cells transfected with the cDNA NOS-3 inserted into the plasmid 4TO; ACTB; actin 1; AL1B1; aldehyde dehydrogenase X; ATPB; ATP synthase subunit beta; CALR; calreticulin; CH60; 60 kDa heat shoc

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

ATF3 represses PDX-1 expression in pancreatic β-cells

Keywords: ChIP; chromatin immunoprecipitation; ER; endoplasmic reticulum; GRP78; glucose-regulated protein 78; eIF2α; elongation initiation factor; SREBP-1c; sterol regulatory element-binding protein-1; Pancreatic and duodenal homeobox factor-1 (PDX-1); Activating

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Purified autoantibodies against glucose-regulated protein 78 (GRP78) promote apoptosis and decrease invasiveness of ovarian cancer cells

Keywords: GRP78; Autoantibodies; Ovarian cancer; Invasion; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Glucose regulated protein 78 (GRP78) is overexpressed in colorectal carcinoma and regulates colorectal carcinoma cell growth and apoptosis

Keywords: Glucose-regulated protein 78; GRP78; Colorectal carcinoma; ShRNA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Sodium phenylbutyrate ameliorates focal cerebral ischemic/reperfusion injury associated with comorbid type 2 diabetes by reducing endoplasmic reticulum stress and DNA fragmentation

Keywords: Focal cerebral ischemia; Sodium 4-phenylbutyrate; Type 2 diabetes; ER stress; GRP78; CHOP/GADD153; Caspase-12; DNA fragmentation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Akt is the downstream target of GRP78 in mediating cisplatin resistance in ER stress-tolerant human lung cancer cells

Keywords: Akt; GRP78; ER stress; Drug resistance; Lung cancer

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Biosynthesis and secretion of mouse cysteine-rich with EGF-like domains 2

Keywords: CRELD2; ER stress; GRP78; Sar1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

A unique P-glycoprotein interacting agent displays anticancer activity against hepatocellular carcinoma through inhibition of GRP78 and mTOR pathways

Keywords: P-glycoprotein; Multidrug resistance; ATPase activity; mTOR pathways; GRP78

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

(−)-Epigallocatechin-3-gallate suppresses growth of AZ521 human gastric cancer cells by targeting the DEAD-box RNA helicase p68

Keywords: CBB; Coomassie Brilliant Blue G-250; Chaps; 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate; CHX; cycloheximide; DAPI; 4′,6-diamino-2-phenylindole; DTT; dithiothreitol; ECL; enhanced chemiluminescence; EC; (−)-epicatechin; ECG; (−)-epicate

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Autophagy, Microbial Sensing, Endoplasmic Reticulum Stress, and Epithelial Function in Inflammatory Bowel Disease

Keywords: Inflammatory Bowel Disease; Crohn's Disease; Ulcerative Colitis; Pathogenesis; Autophagy; Endoplasmic Reticulum Stress; Unfolded Protein Response; Innate Immunity; Genetics; Agr2; anterior gradient gene 2; AIEC; enteroadherent-invasive Escherichia coli; A

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Modulation of the Unfolded Protein Response Is the Core of MicroRNA-122-Involved Sensitivity to Chemotherapy in Hepatocellular Carcinoma

Keywords: miRNA; microRNA; ER; endoplasmic reticulum; PSMD10; proteasome 26S subunit, non-ATPase, 10; CDK4; cyclin-dependent kinase 4; UPR; unfolded protein response; GRP78; glucose-regulated protein 78; HCC; hepatocellular carcinoma; DOX; doxorubicin;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Ischemia induces endoplasmic reticulum stress and cell apoptosis in human brain

Keywords: Ischemia; Human brain; Endoplasmic reticulum stress; GRP78; Caspase-9; Apoptosis

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

PFT-α inhibits antibody-induced activation of p53 and pro-apoptotic signaling in 1-LN prostate cancer cells

Keywords: GRP78; Antibody directed against the COOH-terminal domain of GRP78; PFT-α and p53 regulation; PFT-α and caspase activation; Human prostate cancer;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Insulin modulates induction of glucose-regulated protein 78 during endoplasmic reticulum stress via augmentation of ATF4 expression in human neuroblastoma cells

Keywords: Ac-DEVD-MCA, acetyl-L-aspartyl-L-glutamyl-L-valyl-L-aspartic acid a-(4-methylcoumaryl-7-amide); S.D., standard deviationInsulin; ATF4; ER stress; GRP78; SH-SY5Y

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه