دانلود مقالات ISI درباره Gsk-3Β + ترجمه فارسی

Strategies of biochemical adaptation for hibernation in a South American marsupial, Dromiciops gliroides: 2. Control of the Akt pathway and protein translation machinery

Keywords: 4EBP; eukaryotic translation initiation factor 4E-binding protein; Akt; protein kinase B; eIF2α; eukaryotic translation initiation factor 2A; eIF4e; eukaryotic translation initiation factor 4E; GSK-3α; glycogen synthase kinase 3 alpha; GSK-3β; glycogen

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Discovery of new GSK-3β inhibitors through structure-based virtual screening

Keywords: GSK-3β; Virtual screening; Radiometric assay; Molecular dynamics; 2D similarity search;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Long non-coding RNA Linc00675 suppresses cell proliferation and metastasis in colorectal cancer via acting on miR-942 and Wnt/β-catenin signaling

Keywords: Linc00675; Colorectal cancer; Metastasis; miR-942; GSK-3β; Wnt/β-catenin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

A silyl andrographolide analogue suppresses Wnt/β-catenin signaling pathway in colon cancer

Keywords: CRC; colorectal cancer; TBDPS; tert-butyldiphenylsilyl; GSK-3β; glycogen synthase kinase-3β; TCF/LEF; T-cell factor and lymphoid enhancer factor; PARP-1; poly (ADP-ribose) polymerase-1; Andrographolide analogue; Anti-cancer; Colorectal cancer; Wnt/β-ca

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Cardiomyocyte-specific deletion of GSK-3β leads to cardiac dysfunction in a diet induced obesity model

Keywords: High fat diet; Obesity; GSK-3β; Cardiac function;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Anti-neuroinflammatory effects of SLOH in Aβ-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3β

Keywords: Aβ; Amyloid beta; AD; Alzheimer's disease; ANOVA; Analysis of variance; BBB; Blood-brain barrier; BCA; Bicinchoninic acid; BSA; Bovine serum albumin; COX-2; Cyclooxygenase-2; DAPI; 4′, 6-Diamidine-2′-phenylindole dihydrochloride; DMEM; Dulbecco's m

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Pien-Tze-Huang protects cerebral ischemic injury by inhibiting neuronal apoptosis in acute ischemic stroke rats

Keywords: PZH; Pien-Tze-Huang; MCAO; middle cerebral artery occlusion; Cyt C; cytochrome C; GSK-3β; glycogen synthase kinase-3 beta; TCM; traditional Chinese medicine; TTC; 2,3,5-triphenyltetrazolium chloride; UPLC-MS/MS; ultra-performance liquid chromatography-tr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Insulin signaling acts in adult adipocytes via GSK-3β and independently of FOXO to control Drosophila female germline stem cell numbers

Keywords: Germline stem cells; Adipocytes; Insulin signaling; GSK-3β; Oogenesis; Drosophila;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Wnt pathway activator TWS119 enhances the proliferation and cytolytic activity of human γδT cells against colon cancer

Keywords: ACT; Adoptive cell therapy; APCs; Antigen presenting cells; CAR; Chimeric antigen receptor; CCR5; CC-chemokine receptor 5; CFSE; Carboxyfluorescein succinimidyl ester; CRC; Colorectal cancer; GSK-3β; Glycogen synthase kinase-3β; IFN-γ; Interferon-γ; L

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Swimming exercise reverses CUMS-induced changes in depression-like behaviors and hippocampal plasticity-related proteins

Keywords: AKT; protein kinase B; BDNF; brain-derived neurotrophic factor; CREB; cAMP response element-binding protein; CUMS; chronic unpredictable mild stress; FST; forced swim test; GAP-43; growth-associated protein-43; GSK-3β; glycogen synthase kinase-3β; OFT;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Lithium chloride inhibits StAR and progesterone production through GSK-3β and ERK1/2 signaling pathways in human granulosa-lutein cells

Keywords: Lithium chloride; StAR; Progesterone; GSK-3β; ERK1/2;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

SN56 neuronal cell death after 24 h and 14 days chlorpyrifos exposure through glutamate transmission dysfunction, increase of GSK-3β enzyme, β-amyloid and tau protein levels

Keywords: AChE; acetylcholinesterase; AD; Alzheirmer's disease; α7-nAChRs; alpha7-nicotinic acetylcholine receptors; βAPP; amyloid beta precursor protein; Aβ; amyloid beta protein; BSA; bovine serum albumin; CPF; chlorpyrifos; DMEM; Dulbecco's Modified Eagle's

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Extract from Butea monosperma inhibits β-catenin/Tcf signaling in SW480 human colon cancer cells

Keywords: CRC; colorectal cancer; NBF-BMFE; n-butanol fraction of B. monosperma flower extract; APC; adenomatous polyposis coli; GSK-3β; glycogen synthase kinase 3β; CK1; casein kinase 1; LRP5/6; low density lipoprotein receptor- related protein; Dvl; dishevelled

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Cadmium alters heat shock protein pathways in SN56 cholinergic neurons, leading to Aβ and phosphorylated Tau protein generation and cell death

Keywords: Cadmium neurotoxicity; Cognitive disorders; HSF1; Heat shock proteins; SN56 basal forebrain cholinergic neurons; Aβ; amyloid beta protein; AChE; acetylcholine esterase; βAPP; amyloid beta precursor protein; GSK-3β; glycogen synthase kinase 3 beta; DMSO

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Glycogen synthase kinase 3β inhibition reduces mitochondrial oxidative stress in chronic myocardial ischemia

Keywords: metabolic syndrome; chronic coronary ischemia; glycogen synthase kinase 3B; oxidative stress; collagen; AIF; apoptosis inducing factor; CON; control group; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GSK-3β; glycogen synthase kinase- 3β; GSK-3βI;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Research paperOGT-related mitochondrial motility is associated with sex differences and exercise effects in depression induced by prenatal exposure to glucocorticoids

Keywords: AKT; serine/threonine-protein kinases; DEX; dexamethasone; FST; forced swim test; GCs; Glucocorticoids; GSK-3β; glycogen synthase kinase-3β; Miro; mitochondrial Rho GTPase; OFT; open field test; O-GlcNAc; O-linked β-N-acetylglucosamine; OGA; O-GlcNAcas

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Glycogen synthase kinase-3β inhibition enhances myelination in preterm newborns with intraventricular hemorrhage, but not recombinant Wnt3A

Keywords: Wnt3A; GSK-3β; Oligodendrocyte precursor cell; Myelination; Inflammation; Notch;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

Epithelial mesenchymal transition Transcription Factor (TF): The structure, function and microRNA feedback loop

Keywords: SNAIL; Snail family transcriptional repressor; ZEB; Zinc finger E-box binding homeobox; BMP1; Bone Morphogenetic protein1; TWIST; twist family bHLH transcription factor 1; GSC; goosecoid hemeobox; TGF-β; transforming growth factor beta; NPC; nasopharynge

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

The passive avoidance memory improving effect of curcumin in young adult mice: Considering hippocampal MMP-2, MMP-9 and Akt/GSK3β

Keywords: Curcumin; Memory; Hippocampus; MMP; Akt; GSK-3β;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Elevated O-GlcNAcylation stabilizes FOXM1 by its reduced degradation through GSK-3β inactivation in a human gastric carcinoma cell line, MKN45 cells

Keywords: O-GlcNAcylation; Ubiquitination; FOXM1; GSK-3β;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Morinda officinalis How. - A comprehensive review of traditional uses, phytochemistry and pharmacology

Keywords: MO; Morinda officinalis How.; HNMR; nuclear magnetic resonance spectroscopy; IR; infrared spectroscopy; MS; mass spectrometry; 1HNMR; urine nuclear magnetic resonance 1H; TCM; traditional Chinese medicine; SFDA; State Food and Drug Administration; i.p.; i

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Diabetes mellitus and Alzheimer's disease: GSK-3β as a potential link

Keywords: 3xTg; triple-transgenic; Aβ; β-amyloid; AD; Alzheimer's disease; ADAS-cog; Alzheimer's Disease Assessment Scale-cognitive subscale; Akt; protein kinase B; APP; amyloid precursor protein; CREB; cAMP-response element binding protein; DM; diabetes mell

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Regenerating islet-derived 1α (REG-1α) protein increases tau phosphorylation in cell and animal models of tauopathies

Keywords: REG-1α; Tau; Phosphorylation; Human brain; Cortical neurons; Zebrafish; GSK-3β;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

NMDA receptors inhibit axonal outgrowth by inactivating Akt and activating GSK-3β via calcineurin in cultured immature hippocampal neurons

Keywords: NMDA; N-methyl-D-aspartate; APV; DL-2-amino-5-phosphonovalerate; SD; Sprague Dawley; CsA; Cyclosporine; PFA; paraformaldehyde; RT-PCR; reverse transcription PCR; GSK-3; Glycogen synthase kinase-3; T/D-CRMP-2; collapsin response mediator protein 2; OKA; ok

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Genetic or pharmacological superoxide-hydrogen peroxide imbalances modulate the in vitro effects of lithium on glycogen synthase kinase-3β

Keywords: GSK-3β; Glycogen synthase kinase 3 beta; TNF-α; Tumor necrosis factor alpha; IL-10; Interleukin 10; Li; Lithium; S; Superoxide; HP; Hydrogen peroxide; SNP; Single nucleotide polymorphism; MnSOD/SOD2; Superoxide dismutase manganese-dependent enzyme; MTS;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Therapeutic potentials of Houttuynia cordata Thunb. against inflammation and oxidative stress: A review

Keywords: NCBI; National Centre for Biotechnology Information; SARS; Severe acute respiratory syndrome; NO; Nitric Oxide; LPS; Lipopolysaccharide; NF-κB; Nuclear factor kappa B; ROS; Reactive Oxygen Species; TNF-α; Tumor Necrosis Factor-α; IL; Interleukin; MCP-1

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Grewia tiliaefolia and its active compound vitexin regulate the expression of glutamate transporters and protect Neuro-2a cells from glutamate toxicity

Keywords: Vitexin; Calpain; GLT-1; NMDAR; GSK-3β; Glutamate;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Engineered exosomes: A new promise for the management of musculoskeletal diseases

Keywords: Engineered exosomes; Drug delivery; Musculoskeletal diseases; Regenerative medicine; Oncology; Immune system regulation; 3′UTR; 3′untranslated regions; 6-OHDA; 6-hydroxydopamine; APC; adenomatous polyposis coli; BRD7; bromo-domain-containing protein 7

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Nimodipine attenuates tau phosphorylation at Ser396 via miR-132/GSK-3β pathway in chronic cerebral hypoperfusion rats

Keywords: Chronic cerebral hypoperfusion; Tau phosphorylation; GSK-3β; miR-132; Nimodipine; Rat;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Glucocorticoids induce apoptosis and matrix metalloproteinase-13 expression in chondrocytes through the NOX4/ROS/p38 MAPK pathway

Keywords: Dex; dexamethasone; ROS; reactive oxygen species; NOX; NADPH oxidase; MAPK; mitogen-activated protein kinase; MMP; metalloproteinase; GCs; glucocorticoids; GR; glucocorticoid receptor; OA; osteoarthritis; RA; rheumatoid arthritis; NADPH; nicotinamide aden

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Axonal Activation of the Unfolded Protein Response Promotes Axonal Regeneration Following Peripheral Nerve Injury

Keywords: 2-APB; 2-aminoethoxydiphenyl borate; AD; Alzheimer's disease; ATF6; activating transcription factor 6; BiP; binding immunoglobulin protein; BSA; bovine serum albumin; CHOP; CCAAT enhancer binding protein homologous protein; DRG; dorsal root ganglion; ED

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Astaxanthin: A mechanistic review on its biological activities and health benefits

Keywords: Astaxanthin (PubChem CID: 5368397); Beta-Carotene (PubChem CID: 5280489); Beta-Cryptoxanthin (PubChem CID: 5281235); Canthaxanthin (PubChem CID: 5281227); Lutein (PubChem CID: 5281243); Zeaxanthin (PubChem CID: 5280899); Alpha-Tocopherol (PubChem CID: 149

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Isoliquiritigenin inhibits mouse S180 tumors with a new mechanism that regulates autophagy by GSK-3β/TNF-α pathway

Keywords: Isoliquiritigenin; TNF-α; Autophagy; S180 tumor; GSK-3β;

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Raddeanin A inhibits growth and induces apoptosis in human colorectal cancer through downregulating the Wnt/β-catenin and NF-κB signaling pathway

Keywords: Colorectal cancer (CRC); Wnt/β-catenin pathway; NF-κB pathway; Raddeanin A (RA); GSK-3β;

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

An endogenous and ectopic expression of metabotropic glutamate receptor 8 (mGluR8) inhibits proliferation and increases chemosensitivity of human neuroblastoma and glioma cells

Keywords: SH-SY5Y; U87-MG; LN18; LN229; Chemotherapeutics; GSK-3β;

دانلود رایگان متن کامل مقاله ISI 67 صفحه سال انتشار : 2018 سفارش ترجمه

Emerging role and therapeutic implication of Wnt signaling pathways in liver fibrosis

Keywords: α-SMA; α-smooth muscle actin; ALD; alcoholic liver disease; APC; adenomatous polyposis coli; CamKII; calcium sensitive enzymes calmodulin kinase II; CK1; casein kinase 1; CLD; chronic liver disease; COX-2; cyclooxygenase-2; CTGF; connective tissue growt

دانلود رایگان متن کامل مقاله ISI 73 صفحه سال انتشار : 2018 سفارش ترجمه

The genus Polygonatum: A review of ethnopharmacology, phytochemistry and pharmacology

Keywords: Aβ; Amyloid β-peptide; Ac; acetyl; AD; Alzheimer's disease; APP; Amyloid precursor protein; RAW264.7; Murine macrophage cells; Bel-7402; Human Hepatocellular Carcinoma cell line; BMSCs; Bone marrow stromal cells; ChAT; Choline acetyltransferase; DPPH;

دانلود رایگان متن کامل مقاله ISI 76 صفحه سال انتشار : 2018 سفارش ترجمه

Impact of obesity and overweight on DNA stability: Few facts and many hypotheses

Keywords: AGEs; advanced glycation end products; AP-1; activating protein -1; APE1; apurinic/apyrimidinic endonuclease 1; BER; base excision repair; BMI; body mass index; CAF; cafeteria diet; CAT; Catalase; CBMN-Cyt; cytokinesis block micronucleus cytome assay; CEL

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2018 سفارش ترجمه

The interactions of p53 with tau and Aß as potential therapeutic targets for Alzheimer's disease

Keywords: AD; Alzheimer's disease; AICD; amyloid precursor protein intracellular domain; Aβ; amyloid β peptides; ApoE; apolipoprotein E; APP; amyloid precursor proteins; BACE1; β-site APP cleaving enzyme 1; BIN1; bridging integrator 1; CBP; CREB-binding protei

دانلود رایگان متن کامل مقاله ISI 146 صفحه سال انتشار : 2018 سفارش ترجمه

The origins of rimmed vacuoles and granulovacuolar degeneration bodies are associated with the Wnt signaling pathway

Keywords: AD; Alzheimer's disease; APC; adenomatous polyposis coli; Arf6; ADP-ribosylation factor 6; CK1δ; casein kinase 1δ; Dvl; dishevelled; GSK-3β; glycogen-synthase kinase 3β; GVD; granulovacuolar degeneration; Hsp70; heat shock protein 70; Lrp4; low dens

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

S1PR2 antagonist protects endothelial cells against high glucose-induced mitochondrial apoptosis through the Akt/GSK-3β signaling pathway

Keywords: S1PR2; High glucose; Mitochondrial apoptosis; Akt; GSK-3β;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

ILK regulates MSCs survival and angiogenesis partially through AKT and mTOR signaling pathways

Keywords: ILK; integrin-linked kinase; MSCs; mesenchymal stem cells; VEGF; vascular endothelial growth factor; LV; left ventricular; PCI; percutaneous coronary intervention; CABG; coronary artery bypass grafting; IABP; intraaortic ballon pumping; CsCl; cesium chlor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Mangiferin protects against ‭intestinal ischemia/reperfusion-induced ‭liver injury: ‬‬Involvement of PPAR-‭γ, GSK-3β and Wnt/β-catenin pathway‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬

Keywords: Mangiferin (PubChem CID: 5281647); thiobarbituric acid (PubChem CID: 2723628); malondialdehyde (PubChem CID: 10964); Mangiferin; Intestinal ischemia/reperfusion; PPAR-γ; GSK-3β; Wnt/β-Catenin;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Phenethyl isothiocyanate suppresses cancer stem cell properties in vitro and in a xenograft model

Keywords: Cancer stem cells; PEITC; EpCAM; Oct4; Xenograft model; bFGF; basic fibroblast growth factor; EpICD; intracellular domain of EpCAM; FHL2; four and one-half LIM domains protein 2; GSK-3β; glycogen synthase kinase-3 beta; Lef1; lymphoid enhancer-binding fa

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Molecular basis for the regulation of the circadian clock kinases CK1δ and CK1ε

Keywords: ATP; adenosine triphosphate; CK1; casein kinase 1; CK2; casein kinase 2; CTD; C-terminal domain; TTFL; transcriptional and translational feedback loop; GSK-3β; glycogen synthase kinase 3β; MEFs; mouse embryonic fibroblast cells; ConA; concanavalin A; LP

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Paeoniflorin ameliorates cognitive dysfunction via regulating SOCS2/IRS-1 pathway in diabetic rats

Keywords: Paeoniflorin; Diabetes; Cognitive dysfunction; SOCS2/IRS-1; Tau phosphorylation; Akt; protein kinase B; DE; diabetic encephalopathy; DM; diabetes mellitus; GSK-3β; glycogen synthase kinase-3β; IL-1β; interleukin-1β; IRS-1; insulin receptor substrate-1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

MiR-212-3p inhibits LPS-induced inflammatory response through targeting HMGB1 in murine macrophages

Keywords: LPS; lipopolysaccharide; TLRs; Toll-like receptors; HMGB1; high mobility group box 1; miRNAs; microRNAs; mRNAs; messenger RNAs; siRNA; small interfering RNA; UTR; untranslated region; Mut; mutated; TNF-α; tumor necrosis factor-alpha; IL-6; interleukin-6;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Leptin receptor knockout-induced depression-like behaviors and attenuated antidepressant effects of exercise are associated with STAT3/SOCS3 signaling

Keywords: FST; forced swim test; GSK-3β; glycogen synthase kinase-3β; HDL; high density lipoprotein; IKKβ; inhibitor of κB kinase β; IL; interleukin; LepRb; leptin receptor; NFκB; nuclear factor kappaB; OFT; open field test; PTP1B; protein tyrosine phosphatas

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Remote limb ischemic post conditioning during early reperfusion alleviates cerebral ischemic reperfusion injury via GSK-3β/CREB/ BDNF pathway

Keywords: Cerebral stroke; Bilateral common carotid artery occlusion; Cognitive impairment; Remote limb ischemic post conditioning; GSK-3β;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Systemic and network functions of the microtubule-associated protein tau: Implications for tau-based therapies

Keywords: Aβ; amyloid beta; AD; Alzheimer's disease; AMPAR; AMPA-type glutamate receptor; CNS; central nervous system; FTDP-17; frontotemporal dementia with parkinsonism linked to chromosome 17; GFP; green fluorescent protein; GSK-3β; glycogen synthase kinase-3β

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه