Keywords: GTP، گوانوزین تری فسفات; ERK, extracellular signal-regulated kinase; GTP, guanosine triphosphate; MAPK, mitogen-activated protein kinase; NF1, neurofibromatosis type 1; WT, wild type
مقالات ISI GTP، گوانوزین تری فسفات (ترجمه نشده)
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Epigenetic regulation of G protein coupled receptor signaling and its implications in psychiatric disorders
Keywords: GTP، گوانوزین تری فسفات; GPCRs, Gprotein-coupled receptors; HDAC, histone deacetylase; CNS, central nervous system; GWAS, genome-wide association studies; GEFs, guanine nucleotide exchange factors; GDP, guanosine diphosphate; GTP, guanosine triphosphate; WHO, world health organiz
cGMP signaling as a target for the prevention and treatment of breast cancer
Keywords: GTP، گوانوزین تری فسفات; cAMP, cyclic adenosine monophosphate; cGMP, cyclic guanosine monophosphate; PKG, cGMP-dependent protein kinase; CNG, cyclic nucleotide gated ion channel; COX, cyclooxygenase; GTP, guanosine triphosphate; GMP, guanosine monophosphate; GC, guanylyl cyclase;
Role of GTP-CHI links PAH and TH in melanin synthesis in silkworm, Bombyx mori
Keywords: GTP، گوانوزین تری فسفات; BH4, tetrahydrobiopterin; GTP, guanosine triphosphate; H2NTP, 7,8-dihydroneopterin triphosphate; PTP, 6-pyruvoyl-5,6,7,8-tetrahydropterin; 4-OH-BH4, terin-4a-carbinolamine; q-BH2, quinonoid dihydrobiopterin; GTP-CH I, guanosine triphosphate cyclohydrolase
Phagocyte-like NADPH oxidase (Nox2) promotes activation of p38MAPK in pancreatic β-cells under glucotoxic conditions: Evidence for a requisite role of Ras-related C3 botulinum toxin substrate 1 (Rac1)
Keywords: GTP، گوانوزین تری فسفات; 2-BP, 2-bromopalmitate; Cdc42, cell division control protein 42; DCFDA, 2′,-7′-dichlorofluorescein diacetate; GDP, guanosine diphosphate; GTP, guanosine triphosphate; GGTI, geranylgeranyl transferase inhibitor; GSIS, glucose stimulated insulin secretion;
Improved peak identification in 31P-NMR spectra of environmental samples with a standardized method and peak library
Keywords: GTP، گوانوزین تری فسفات; 2-AEP, 2-aminoethylphosphonic acid; ADP, adenosine diphosphate; ATP, adenosine triphosphate; CWAs, chemical weapons agents; DNA, deoxyribonucleic acid; EDTA, ethylenediaminetetra-acetic acid; GTP, guanosine triphosphate; IHP, inositol hexakisphosphate; LB
Somatostatin 4 receptor activation modulates G-protein coupled inward rectifying potassium channels and voltage stimulated calcium signals in dorsal root ganglion neurons
Keywords: GTP، گوانوزین تری فسفات; ATP, adenosine triphosphate; CNS, central nervous system; DMEM, Dulbecco׳s Modified Eagle Medium; DRG, dorsal root ganglion neurons; GIRK, G-protein inward rectifying potassium channels; GPCR, G protein coupled receptor; GTP, guanosine triphosphate; HEPES
Higher prevalence of KRAS mutations in colorectal cancer in Saudi Arabia: Propensity for lung metastasis
Keywords: GTP، گوانوزین تری فسفات; 5FU, Fluorouracil; AJCC, American Joint Committee on Cancer; BRAF, v-rafmurine sarcoma viral oncogene homolog B1; CR, complete response; CRC, colorectal cancer; EGFR, epidermal growth factor receptor; GDP, guanosinediphosphate; GTP, guanosine triphosphate
GCH1 variants, tetrahydrobiopterin and their effects on pain sensitivity
Keywords: GTP، گوانوزین تری فسفات; CFA, Complete Freund’ Adjuvant; DAHP, 2,4-diamino-6-hydroxypyrimidine; DHPR, dihydropteridine reductase; l-DOPA, l-3,4-dihydroxyphenylalanine; DRG, dorsal root ganglia; GCH1, GTP cyclohydrolase 1; GTP, guanosine triphosphate; NAS, N-acetylserotonin; NO, n
An evaluation of genetically encoded FRET-based biosensors for quantitative metabolite analyses in vivo
Keywords: GTP، گوانوزین تری فسفات; AxP, AMP ADP ATP; GTP, guanosine triphosphate; cGMP, cyclic guanosine monophosphate; EYFP, enhanced yellow fluorescent protein; ECFP, enhanced cyan fluorescent protein; FP, fluorescent proteinGFP; EYFP; ECFP; Citrine; Intracellular metabolite analysis
Localization of primary cilia in mouse retina
Keywords: GTP، گوانوزین تری فسفات; ADP, adenosine diphosphate; AMP, adenosine monophosphate; Arl13b, ADP-ribosylation factor-like protein 13B; ATP, adenosine triphosphate; CC, connecting cilium; GCL, ganglion cell layer; GST, glutathione-S-transferase; GTP, guanosine triphosphate; IFT, int
Biotechnological production of feed nucleotides by microbial strain improvement
Keywords: GTP، گوانوزین تری فسفات; AMP, adenosine monophosphate; CMP, cytidine monophosphate; GMP, guanosine monophosphate; GDP, guanosine diphosptate; GTP, guanosine triphosphate; ppGpp, guanosine tetraphosphate; cGMP, cyclic GMP; IMP, inosine monophosphate; UMP, uridine monophosphate; XM
NOXious signaling in pain processing
Keywords: GTP، گوانوزین تری فسفات; DRG, dorsal root ganglion; DPI, diphenylene iodonium; DUOX, dual oxidase; GSH, glutathione; GTP, guanosine triphosphate; IL, interleukin; LTP, long-term potentiation; MAP, mitogen-activated kinase; NMDA, N-methyl-D-aspartate; NADPH, nicotinamide adenine d
The human ITPA polymorphic variant P32T is destabilized by the unpacking of the hydrophobic core
Keywords: GTP، گوانوزین تری فسفات; ATP, adenosine triphosphate; βME, β-mercaptoethanol; CT, C-terminus; GTP, guanosine triphosphate; HAP, 6-hydroxylaminopurine; HSP, heat shock protein; ITP, inosine triphosphate; ITPA, inosine triphosphate pyrophosphatase; NT, N-terminus; NUDT16, nudix-typ
GTP binds to α-crystallin and causes a significant conformational change
Keywords: GTP، گوانوزین تری فسفات; ATP, adenosine triphosphate; bisANS, 1,1′-bi (4-anilino) naphthalene-5,5′-disulfonic acid, dipotassium salt; GTP, guanosine triphosphate; NATA, N-acetyl-tryptophanamide; TNP-GTP, 2′,3′-O-(2,4,6-trinitrocyclohexadienylidene)-guanosine triphosphate; SDS-PAG
A sensitive HPLC-based method to quantify adenine nucleotides in primary astrocyte cell cultures
Keywords: GTP، گوانوزین تری فسفات; AEC, adenylate energy charge; HPLC, high performance liquid chromatography; ADO, adenosine; AMP, adenosine monophosphate; ADP, adenosine diphosphate; ATP, adenosine triphosphate; AMPCP, α, β-methylene adenosine diphosphate; GTP, guanosine triphosphate; NA
Role of Epac and protein kinase A in thyrotropin-induced gene expression in primary thyrocytes
Keywords: GTP، گوانوزین تری فسفات; ATC, anaplastic thyroid carcinoma; Epac, exchange protein directly activated by cAMP; FSK, forskolin; GEF, guanine nucleotide exchange factor; GDP, guanosine diphosphate; GTP, guanosine triphosphate; MDS, multidimensional scaling; PKA, protein kinase A; P
Cooling-increased phospho-β-arrestin-1 and β-arrestin-1 expression levels in 3T3-L1 adipocytes
Keywords: GTP، گوانوزین تری فسفات; AMPK, AMP-activated protein kinase; cAMP, cyclic adenosine 3′,5′-monophosphate; ERK, extracellular signal-regulated kinase; 4E-BP1, eIF4E-binding protein 1; Gs, stimulatory GTP-binding protein; GTP, guanosine triphosphate; HEK, human embryonic kidney; IGF
R-isovaline: a subtype-specific agonist at GABAB-receptors?
Keywords: GTP، گوانوزین تری فسفات; isovaline; GABAB receptors; K+ channels; thalamus; ventrobasal nuclei; analgesiaaCSF, artificial cerebrospinal fluid; DAPI, 4',6-diamidino-2-phenylindole; Ek, equilibrium potential for K+; GDP-β-S, 5′-[β-thio]diphosphate; GTP, guanosine triphosphate; GTP-
CIL-102 binds to tubulin at colchicine binding site and triggers apoptosis in MCF-7 cells by inducing monopolar and multinucleated cells
Keywords: GTP، گوانوزین تری فسفات; GTP, guanosine triphosphate; PIPES, piperazine-N,N′-bis(2-ethanesulfonic acid); EGTA, ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′ tetraacetic acid; FITC, fluorescein isothiocyanate; DTNB, 5, 5′-dithiobis-2-nitrobenzoic acid; DMSO, dimethyl sulfoxide
Endothelins & erectile dysfunction
Keywords: GTP، گوانوزین تری فسفات; ED, erectile dysfunction; QoL, quality of life; CC, corpora cavernosa; Ca2+, calcium; ET, endothelin; ET-1, endothelin-1; ET-2, endothelin-2; ET-3, endothelin-3; SMCs, smooth muscle cells; GDP, guanosine diphosphate; GTP, guanosine triphosphate; cGMP, cyc
Pleiotropic effect of a null mutation in the cvn1 conservon of Streptomyces coelicolor A3(2)
Keywords: GTP، گوانوزین تری فسفات; cvn, conservon; ATP, adenosine triphosphate; GTP, guanosine triphosphate; bp, base pairs; kb, kilo-base pairs; s, second; d, day; h, hourcvn1; Conservon; Streptomyces coelicolor A3(2); Morphological differentiation; Secondary metabolism
Cyclic di-GMP Activation of Polynucleotide Phosphorylase Signal-Dependent RNA Processing
Keywords: GTP، گوانوزین تری فسفات; c-di-GMP, cyclic diguanylic acid; DOS-RNC, Dos ribonucleoprotein complex; GTP, guanosine triphosphate; GDP, guanosine diphosphate; DosC, direct O2-sensing cyclase; DosP, direct O2-sensing phosphodiesterasedegradosome; EAL domain; GGDEF domain; oxygen sens
Up-regulation of low-threshold tetrodotoxin-resistant Na+ current via activation of a cyclic AMP/protein kinase A pathway in nociceptor-like rat dorsal root ganglion cells
Keywords: GTP، گوانوزین تری فسفات; NaV1.9; NaV1.8; A-803467; sensory neuron; hyperalgesia; inflammationAC, adenylyl cyclase; A-D/D-A, analog to digital/digital to analog; cAMP, cyclic AMP; DRG, dorsal root ganglion; EGTA, ethylene glycol tetraacetic acid; GTP, guanosine triphosphate; HEPES
Wounding systemically activates a mitogen-activated protein kinase in forage and turf grasses
Keywords: GTP، گوانوزین تری فسفات; ABA, abscisic acid; ERK, extracellular signal regulated kinase; GTP, guanosine triphosphate; JA, jasmonic aci0d; Lt, Lolium temulentum; MAPK, mitogen-activated protein kinase; MJ, methyl jasmonate; NADPH, nicotinamide adenine dinucleotide phosphate; PAGE,
Disorders of BH4 metabolism and the treatment of patients with 6-pyruvoyl-tetrahydropterin synthase deficiency in Taiwan
Keywords: GTP، گوانوزین تری فسفات; Hyperphenylalaninemia; 6-pyruvoyl-tetrahydropterin synthase; Tetrahydrobiopterin; BH4; Treatment; OutcomeAR, aldose reductase; BH4, tetrahydrobiopterin; CR, carbonyl reductase; DHPR, dihydropteridine reductase; GTP, guanosine triphosphate; GTPCH, guanosin
A farnesylated G-protein suppresses Akt phosphorylation in INS 832/13 cells and normal rat islets: Regulation by pertussis toxin and PGE2
Keywords: GTP، گوانوزین تری فسفات; Erk, extracellular signal regulated kinase; FoxO1, Forkhead box protein O1; FTI, farnesyl transferase inhibitor; FTase, farnesyl transferase; GTP, guanosine triphosphate; IGF-1, insulin-like growth factor-1; MEK, mitogen activated extracellular kinase; MP
MAGI-3 Competes With NHERF-2 to Negatively Regulate LPA2 Receptor Signaling in Colon Cancer Cells
Keywords: GTP، گوانوزین تری فسفات; G-Protein Signaling; Colorectal Cancer; Neoplasia; TumorigenesisGPCR, G-protein–coupled receptors; GTP, guanosine triphosphate; IκBα, inhibitory kappa Bα; JNK, c-Jun N-terminal kinase; LPA, lysophosphatidic acid; MAGI-3, membrane-associated guanylate kina
Serotonin receptors and heart valve disease—It was meant 2B
Keywords: GTP، گوانوزین تری فسفات; 5-HT, 5-hydroxytryptomine; AT1R, angiotensin II type 1 receptor; CHD, carcinoid heart disease; ECM, extracellular matrix; GPCR, G protein-coupled receptor; GTP, guanosine triphosphate; HV, heart valve; HVD, heart valve disease; MAPK, mitogen activated pro
Mechanisms of HO-1 mediated attenuation of renal immune injury: a gene profiling study
Keywords: GTP، گوانوزین تری فسفات; ER, endoplasmic reticulum; cDNA, complementary DNA; FDR, false discovery rate; GBM, glomerular basement membrane; GEC, glomerular epithelial cell; GFR, glomerular plasma filtration rate; GN, glomerulonephritis; GTP, guanosine triphosphate; HO, heme oxygen
Electron tomographic analysis of gap junctions in lateral giant fibers of crayfish
Keywords: GTP، گوانوزین تری فسفات; ATP, adenosine triphosphate; cAMP, cyclic adenosine monophosphate; CSV, chemical synaptic vesicle; GJV, gap junctional vesicle; GTP, guanosine triphosphate; LGF, lateral giant fiber; OsO4, osmium tetraoxide; PSD, post-synaptic density; EM, electron micros
Different Requirements for σ Region 4 in BvgA Activation of the Bordetella pertussis Promoters Pfim3 and PfhaB
Keywords: GTP، گوانوزین تری فسفات; BvgA; fim; sigma; polymerase; promoterCTD, C-terminal domain; RNAP, RNA polymerase; wt, wild type; PDB, Protein Data Bank; BG, Bordet–Gengou; MCS, multi-cloning site; EDTA, ethylenediaminetetraacetic acid; GTP, guanosine triphosphate; TBE, Tris/borate/EDT
The association between serum levels of neopterin and number of depressive episodes of major depression
Keywords: GTP، گوانوزین تری فسفات; CRP, C-reactive protein; DSM-IV, Diagnostic and Statistical Manual of Mental Disorders; GTP, guanosine triphosphate; HDS, Hamilton Depression Scale; HPLC, high performance liquid chromatography; IFN, interferon; IL, interleukin; MD, major depression; OCD,
Dihydropteridine reductase activity in the brainstem of intrauterine growth-restricted rats
Keywords: GTP، گوانوزین تری فسفات; IUGR, intrauterine growth restriction; 5-HT, 5-Hydroxytryptamine; BH4, tetrahydrobiopterin; l-Trp, l-tryptophan; Tph, tryptophan-5-hydroxylase; 5-HTP, 5-hydroxytryptophan; GTP, guanosine triphosphate; NADPH, nicotinamide adenine dinucleotide reduced; DHPR
Necrotic core in EMT6/Ro tumour spheroids: Is it caused by an ATP deficit?
Keywords: GTP، گوانوزین تری فسفات; ATP, adenosine triphosphate; ADP, adenosine diphosphate; Pi, inorganic orthophosphate; GTP, guanosine triphosphate; GDP, guanosine diphosphate; NAD+, nicotinamide adenine dinucleotide (oxidized form); NADH, nicotinamide adenine dinucleotide (reduced form)
Design, synthesis and evaluation of analogs of initiation factor 4E (eIF4E) cap-binding antagonist Bn7-GMP
Keywords: GTP، گوانوزین تری فسفات; eIF4E; Translation initiation; Anticancer; Antifibrotic; CoMFA; CoMSIABn7-GMP, N7-benzylated guanosine monophosphate; GDP, Guanosine diphosphate; GTP, Guanosine triphosphate; EWG, Electron withdrawing group; EDG, Electron donating group; ESI-MS, Electrosp
Backbone conformational flexibility of the lipid modified membrane anchor of the human N-Ras protein investigated by solid-state NMR and molecular dynamics simulation
Keywords: GTP، گوانوزین تری فسفات; DIPSHIFT, dipolar coupling and chemical shift; DMPC, 1,2-dimyristoyl-phosphocholine; FSLG, frequency-switched Lee-Goldburg; GTP, guanosine triphosphate; MAS, magic-angle spinning; MD, molecular dynamics; NMR, nuclear magnetic resonance; NOE, nuclear Overh
HMBA depolymerizes microtubules, activates mitotic checkpoints and induces mitotic block in MCF-7 cells by binding at the colchicine site in tubulin
Keywords: GTP، گوانوزین تری فسفات; IgG, immunoglobulin G; GTP, guanosine triphosphate; GDP, guanosine diphosphate; FITC, fluorescein isothiocyanate; ANS, 1-anilinonaphthalene-8-sulfonic acid; EGTA, ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid; DAMA–colchicine, N-deace
Developmental changes of gene expression after spinal cord injury in neonatal opossums
Keywords: GTP، گوانوزین تری فسفات; AMP, Adenosine monophosphate; BSA, Bovine serum albumin; CNS, Central nervous system; DAPI, 4′,6-diamidino-2-phenylindole; ExPASy, Expert Protein Analysis System; GTP, Guanosine triphosphate; NCBI, National Center for Biotechnology Information; P8, Postna
The R1441C mutation alters the folding properties of the ROC domain of LRRK2
Keywords: GTP، گوانوزین تری فسفات; DSF, differential scanning fluorimetry; CD, circular dichroism; GDP, guanosine diphosphate; GTP, guanosine triphosphate; LRRK2, leucine rich repeat kinase 2; ROC, Ras of complex proteins; PD, Parkinson's diseaseLRRK2; ROCO protein; GTPase; Parkinson's dis
In a Head-on Collision, Two RNA Polymerases Approaching One Another on the Same DNA May Pass by One Another
Keywords: GTP، گوانوزین تری فسفات; RNAP, RNA polymerase; EC, elongation complex; GTP, guanosine triphosphate; UTP, uridine triphosphate; dCTP, deoxycytidine triphosphateTranscription; replication forks; template strand; RNA polymerase
Cocaine regulates ezrin–radixin–moesin proteins and RhoA signaling in the nucleus accumbens
Keywords: GTP، گوانوزین تری فسفات; cocaine; ERM; RhoA; nucleus accumbens; structural plasticity; addictionANOVA, analysis of variance; ERM, ezrin–radixin–moesin; GST, glutathione S-transferase; GTP, guanosine triphosphate; MLB, Mg2+ lysis/wash buffer; MYPT, myosin-binding subunit of myosin
Gtr1p differentially associates with Gtr2p and Ego1p
Keywords: GTP، گوانوزین تری فسفات; TOR, target of rapamycin; SDS-PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresis; GTP, Guanosine Triphosphate; GDP, Guanosine Diphosphate; DBD, DNA binding domain; AD, Activation Domain; HA, hemagglutinin; Mr, Molecular weight; PDB, Protein D
P120-Ras GTPase activating protein (RasGAP): A multi-interacting protein in downstream signaling
Keywords: GTP، گوانوزین تری فسفات; Ras; p120-RasGAP; SH2 domain; SH3 domainp120-RasGAP, Ras GTPase activating protein; GDP, guanosine diphosphate; GTP, guanosine triphosphate; GTPase, guanosine triphosphatase; GAP, GTPase-activating proteins; Dok, downstream of tyrosine kinase; PI-3K, phos
Understanding the Sequence Specificity of tRNA Binding to Elongation Factor Tu using tRNA Mutagenesis
Keywords: GTP، گوانوزین تری فسفات; EF-Tu, elongation factor Tu; aa, aminoacyl; GTP, guanosine triphosphate; A helix/stem, acceptor helix/stem; T helix/stem, TΨC helix/stem; TCA, trichloroacetic acidEF-Tu; tRNA mutagenesis; tRNA protein interaction; T stem; thermodynamic compensation
Determination of marker pteridins and biopterin reduced forms, tetrahydrobiopterin and dihydrobiopterin, in human urine, using a post-column photoinduced fluorescence liquid chromatographic derivatization method
Keywords: GTP، گوانوزین تری فسفات; BH4, tetrahydrobiopterin; GTP, guanosine triphosphate; PAH, phenylalanine-4-hydroxylase; TH, tyrosine-3-hydroxylase; TPH, tryptophan-5-hydroxylase; BH2, dihydrobiopterin; DHPR, dihydropteridine reductase; NEO, neopterin; BIO, biopterin; ISO, isoxanthopter
OPA1-associated disorders: Phenotypes and pathophysiology
Keywords: GTP، گوانوزین تری فسفات; ADOA, autosomal dominant optic atrophy; ADOAC, autosomal dominant optic atrophy and cataract; ADOAD, autosomal dominant optic atrophy and deafness; ATP, adenosine triphosphate; FISH, fluorescent in situ hybridisation; GTP, guanosine triphosphate; GTPase,
Clostridium difficile Infection Caused by the Epidemic BI/NAP1/027 Strain
Keywords: GTP، گوانوزین تری فسفات; BCAA, branched-chain amino acid; CDI, Clostridium difficile infection; CDT, C difficile binary toxin; CdtLoc, CDT locus; GTP, guanosine triphosphate; PaLoc, pathogenicity locus; PCR, polymerase chain reaction; REA, restriction endonuclease analysis
Structural and Kinetic Studies of the Allosteric Transition in Sulfolobus solfataricus Uracil Phosphoribosyltransferase: Permanent Activation by Engineering of the C-Terminus
Keywords: GTP، گوانوزین تری فسفات; GTP, guanosine triphosphate; CTP, cytidine triphosphate; UMP, uridine monophosphate; PRTase, phosphoribosyltransferase; UPRTase, uracil PRTase or UMP synthase (EC 2.4.2.9); PRPP, 5-phosphoribosyl-1-α-diphosphate; PPi, diphosphate; R5P, ribose-5-phosphate;
Transduction mechanisms of photoreceptor signals in plant cells
Keywords: GTP، گوانوزین تری فسفات; cAMP, adenosine-3′,5′-cyclophosphate or 3′,5′-cyclo-AMP; AMP, adenosine-5′-monophosphate; GMP, guanosine monophosphate; GTP, guanosine triphosphate; GC, guanylyl cyclase; IP3, inositol-1,4,5-triphosphate; PIP2, phosphatidylinositol-4,5-diphosphate; phy, p