Keywords: عوامل مبادله نوکلئوتیدی گوانین; ADAM; a disintegrin and metalloproteinase; AKT; protein kinase B; APAF 1; apoptotic protease activating factor 1; APC; adenomatous polyposis coli; ATG; autophagy protein; BAK; Bcl 2 homologous antagonist/killer; BAX; Bcl-2 associated -X protein; Bcl-2; B-
مقالات ISI عوامل مبادله نوکلئوتیدی گوانین (ترجمه نشده)
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Keywords: عوامل مبادله نوکلئوتیدی گوانین; Cancer stem-like cells; Mevalonate cascade; Ras; Rho; Stemness; Statins; Yap; ACAT; acetoacetyl-CoA transferase; acetyl-CoA; acetyl-coenzyme A; Arp2/3; actin-related protein 2/3 (actin polymerizing complex); BPs; bisphosphonates; CAMs; cell adhesion molec
Keywords: عوامل مبادله نوکلئوتیدی گوانین; OS; overall survival; MAPK; mitogen-activated protein kinase; RTKs; receptor tyrosine kinases; PI3K; phosphatidylinositide 3-kinases; GEFs; guanine nucleotide exchange factors; GAPs; GTPase-activating proteins; FTIs; farnesyltransferase inhibitors; mTOR;
IL-21 alleviates allergic asthma in DOCK8-knockout mice
Keywords: عوامل مبادله نوکلئوتیدی گوانین; DOCK8 gene; Allergic asthma; Ovalbumin; Murine model; IL-21; rmIL-21; recombinant mouse interleukin-21; DOCK8; dedicator of cytokinesis 8; STAT3; signal transducer and activator of transcription 3; TYK2; tyrosine kinase 2; DIDS; DOCK8 immunodeficiency syn
KRAS-Mutant non-small cell lung cancer: From biology to therapy
Keywords: عوامل مبادله نوکلئوتیدی گوانین; BATTLE; Biomarker-Integrated Approaches of Targeted Therapy for Lung Cancer Elimination; BET; bromodomains and extra-terminal domain; CDK; cyclin-dependent kinase; Chk1; checkpoint kinase 1; CI; confidence interval; CUSTOM; Molecular Profiling and Targete
Enteropathogenic Escherichia coli EspH-Mediated Rho GTPase Inhibition Results in Desmosomal Perturbations
Keywords: عوامل مبادله نوکلئوتیدی گوانین; EPEC; Desmoglein; DSG2; Host-Pathogen Interaction; A/E; attaching and effacing; BSA; bovine serum albumin; CM; calcium and magnesium; DMEM; Dulbecco's modified Eagle medium; DSC; desmocollin; DSG; desmoglein; EPEC; enteropathogenic Escherichia coli; GE
A Schizophrenia-Linked KALRN Coding Variant Alters Neuron Morphology, Protein Function, and Transcript Stability
Keywords: عوامل مبادله نوکلئوتیدی گوانین; Dendrites; Dendritic spines; Guanine nucleotide exchange factors; Kalirin; Schizophrenia; Single nucleotide variants;
EMT: Mechanisms and therapeutic implications
Keywords: عوامل مبادله نوکلئوتیدی گوانین; AJ; adherens junction; aPKC; atypical protein kinase; BM; basement membrane; βHLH; Beta helix-loop-helix; CSC; cancer stem cells; ECM; extracellular matrix; EMT; epithelial mesenchymal transition; FOX; Forkhead box; GAP; GTPase-activating proteins; GDI;
Tiam1/Vav2-Rac1 axis: A tug-of-war between islet function and dysfunction
Keywords: عوامل مبادله نوکلئوتیدی گوانین; HG; high glucose; GEFs; guanine nucleotide exchange factors; GSIS; glucose-stimulated insulin secretion; NOD mice; nonobese diabetic mice; Nox2; phagocyte-like NADPH oxidase; Rac1; Ras-related C3 botulinum toxin substrate 1; ROS; reactive oxygen species;
The small GTPase Arf6 regulates sea urchin morphogenesis
Keywords: عوامل مبادله نوکلئوتیدی گوانین; PMCs; primary mesenchyme cells; DVC rod; dorsoventral connecting rod; EMT; epithelial to mesenchymal transition; MASO; antisense morpholino oligonucleotide; GEF; guanine nucleotide exchange factors; GAPs; GTPase activating proteins; Primary mesenchyme cel
ROS-dependent activation of RhoA/Rho-kinase in pulmonary artery: Role of Src-family kinases and ARHGEF1
Keywords: عوامل مبادله نوکلئوتیدی گوانین; Vascular smooth muscle; Tyrosine kinases; Src-family kinases; Reactive oxygen species; Hypoxia; Rho-kinase; Guanine nucleotide exchange factors; Pulmonary artery;
Directional Migration in Esophageal Squamous Cell Carcinoma (ESCC) is Epigenetically Regulated by SET Nuclear Oncogene, a Member of the Inhibitor of Histone Acetyltransferase Complex
Keywords: عوامل مبادله نوکلئوتیدی گوانین; ESCC; Esophageal squamous cell carcinoma; SET; SET nuclear oncogene; GEFs; Guanine nucleotide exchange factors; INHAT; Inhibitor of acetyltransferases; NAT; Natural antisense transcript;
Cytoskeletal remodeling via Rho GTPases during oxidative and thermal stress in Caenorhabditis elegans
Keywords: عوامل مبادله نوکلئوتیدی گوانین; Actin; Oxidative stress; Heat shock; Rho signaling; Guanine nucleotide exchange factors;
Nudix-type motif 2 contributes to cancer proliferation through the regulation of Rag GTPase-mediated mammalian target of rapamycin complex 1 localization
Keywords: عوامل مبادله نوکلئوتیدی گوانین; mTORC1; mammalian target of rapamycin complex 1; NUDT2; Nudix-type motif 2; GEFs; guanine nucleotide exchange factors; GAPs; GTPase-activating proteins; Ap4A; 5â², 5â³-p1,p4-tetraphosphate; DCIS; ductal cell in situ; IDC; invasive ductal carcinoma cell;
Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRP
Keywords: عوامل مبادله نوکلئوتیدی گوانین; BCl3; boron trichloride; CAN; ceric ammonium nitrate; DAG; diacylglycerol; DBU; 1,8-diazabicyclo[5.4.0]undec-7-ene; DMAP; 4-dimethylaminopyridine; GEFs; guanine nucleotide exchange factors; LiHMDS; lithium hexamethyldisilazide; MRCKs; myotonic dystrophy k
Redox regulation of the actin cytoskeleton and its role in the vascular system
Keywords: عوامل مبادله نوکلئوتیدی گوانین; α; alpha; β; beta; γ; gamma; G-actin; globular actin; F-actin; filamentous actin; ROS; reactive oxygen species; O2â¢â; superoxide; H2O2; hydrogen peroxide; HOâ¢; hydroxyl radical; RNS; reactive nitrogen species; NO; nitric oxide; â¢NO2; nitrogen d
Cell type-specific roles of RAS-MAPK signaling in learning and memory: Implications in neurodevelopmental disorders
Keywords: عوامل مبادله نوکلئوتیدی گوانین; CFC; cardio-facio-cutaneous; CS; Costello syndrome; FACS; fluorescence-activated cell sorting; GAPs; GTPase activating proteins; GEFs; guanine nucleotide exchange factors; GFP; green fluorescent protein; HCN; hyperpolarization-activated cyclic nucleotide-
Review articleRegulating G protein activity by lipase-independent functions of phospholipase C
Keywords: عوامل مبادله نوکلئوتیدی گوانین; Ca2 +;  G proteins; G protein-coupled receptor; GTPase activating protein; Guanine nucleotide exchange factors; Phosphatidic acid; Phospholipase C-β;
Crystal structure of GTPase-activating domain from human MgcRacGAP
Keywords: عوامل مبادله نوکلئوتیدی گوانین; MgcRacGAP; male germ cell RacGap; MKLP1; mitotic kinesin-like protein 1; GAPs; GTPase-activating proteins; GEFs; guanine nucleotide exchange factors; GST; glutathione S-transferase; TEV; tobacco etch virus; IPTG; isopropyl-β-d-1-thiogalactopyranoside; PM
Ric-8A, a guanine nucleotide exchange factor for heterotrimeric G proteins, is critical for cranial neural crest cell migration
Keywords: عوامل مبادله نوکلئوتیدی گوانین; Ric-8A; Neural crest; Cell migration; Xenopus; Cell adhesion; Guanine nucleotide Exchange Factors;
Glutathiolated Ras: Characterization and implications for Ras activation
Keywords: عوامل مبادله نوکلئوتیدی گوانین; BAEC; bovine aortic endothelial cell; DAF; diaminofluorescein; DEANO; diethylammonium (Z)-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate; eNOS; endothelial nitric oxide synthase; GAP; GTPase activating protein; GEF; guanine nucleotide exchange factors; HCD;
Epac activator critically regulates action potential duration by decreasing potassium current in rat adult ventricle
Keywords: عوامل مبادله نوکلئوتیدی گوانین; cAMP; cyclic adenosine 3â², 5â²-monophosphate; PKA; cAMP-dependent protein kinase; IK; delayed rectifier potassium current; Epac; exchange proteins directly activated by cAMP; GEF; guanine nucleotide exchange factors; ICa; L-type calcium current; PDE; p
Increased expression of Dock180 protein in the noninfarcted myocardium in rats
Keywords: عوامل مبادله نوکلئوتیدی گوانین; guanine nucleotide exchange factors; myocardial infarction; myocardium; proteins; rats
Immune regulatory functions of DOCK family proteins in health and disease
Keywords: عوامل مبادله نوکلئوتیدی گوانین; Migration; Activation; Leukocytes; Small GTPases; Guanine nucleotide exchange factors
Selective interactions of spinophilin with the C-terminal domains of the δ- and μ-opioid receptors and G proteins differentially modulate opioid receptor signaling
Keywords: عوامل مبادله نوکلئوتیدی گوانین; GPCR; G protein-coupled receptors; RGS; Regulators of G protein Signaling; ÎÎRGS4; RGS4 lacking its N-terminal domain; 6xHis; hexahistidine; aa; amino acids; GEFs; Guanine nucleotide exchange factors; AC; adenylyl cyclase; DAMGO; [D-Ala2,N-MePhe4,Gly5-o
Rap-linked cAMP signaling Epac proteins: Compartmentation, functioning and disease implications
Keywords: عوامل مبادله نوکلئوتیدی گوانین; Guanine nucleotide exchange factors; cAMP; PKA; CaMKII; Phosphodiesterase; Compartmentation; G protein-coupled receptor
The RasGrf family of mammalian guanine nucleotide exchange factors
Keywords: عوامل مبادله نوکلئوتیدی گوانین; GEFs; guanine nucleotide exchange factors; NMDA; N-methyl-d-aspartate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; CNS; Central Nervous System; DMD; differentially methylated domain; CTCF; CCCTC-binding protein; CDB; cyclin destruction b
GrinchGEF-A novel Rho-specific guanine nucleotide exchange factor
Keywords: عوامل مبادله نوکلئوتیدی گوانین; Dbl family; Guanine nucleotide exchange factors; Rho proteins; Signal transduction;
Ca2+ sensitization and the regulation of contractility in rat anococcygeus and retractor penis muscle
Keywords: عوامل مبادله نوکلئوتیدی گوانین; CCh; carbachol; EFS; electrical field stimulation; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GEFs; guanine nucleotide exchange factors; GPCR; G protein coupled-receptor; HA-1077; (5-isoquinolinesulfonyl)homopiperazine; H-1152; (S)-(+)-2-methyl-1-[(
E3B1, a human homologue of the mouse gene product Abi-1, sensitizes activation of Rap1 in response to epidermal growth factor
Keywords: عوامل مبادله نوکلئوتیدی گوانین; Abi-1; Abl-interactor-1; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; GAP; GTPase-activating protein; GEFs; guanine nucleotide exchange factors; GST; glutathione-S-transferase; mAb; monoclonal antibody; pAb; polyclonal antibody; P