دانلود مقالات ISI درباره Gw501516 + ترجمه فارسی

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Blockage of progesterone receptor effectively protects pancreatic islet beta cell viability

Keywords: PR; progesterone receptor; PIC; pro-inflammatory cytokines; P4; progesterone; Erk; extracellular-signal-regulated kinase 1/2; p53; protein 53; AKT; protein kinase B; TRAF2; tumor necrosis factor receptor-associated factor 2; PR-KO; PR knockout; Mif; mifep

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Highly selective peroxisome proliferator-activated receptor δ (PPARδ) modulator demonstrates improved safety profile compared to GW501516

Keywords: PPARδ modulator; GW501516; Gene expression; Thermal injury model; Ki-67;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2018 سفارش ترجمه

Novel highly selective peroxisome proliferator-activated receptor δ (PPARδ) modulators with pharmacokinetic properties suitable for once-daily oral dosing

Keywords: PPARδ modulator; GW501516; Plasma exposure; Ligand binding domain; X-ray structure;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Early controlled release of peroxisome proliferator-activated receptor β/δ agonist GW501516 improves diabetic wound healing through redox modulation of wound microenvironment

Keywords: Diabetic wound healing; Hydrogen peroxide; Microparticle; Peroxisome proliferator-activated receptor beta/delta; Controlled release; GW501516;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Activation of PPARβ/δ protects pancreatic β cells from palmitate-induced apoptosis by upregulating the expression of GLP-1 receptor

Keywords: PPARβ/δ; peroxisome proliferator-activated receptor β/δ; GLP-1R; glucagon-like peptide-1 receptor; GW; GW501516; PA; palmitate; qPCR; quantitative polymerase chain reaction; SREBP-1c; sterol regulatory element binding protein-1c; GSIS; glucose-stimula

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

PPAR activation as a regulator of lipid metabolism, nitric oxide production and lipid peroxidation in the placenta from type 2 diabetic patients

Keywords: GDM; gestational diabetes mellitus; PPAR; peroxisome proliferator activated receptor; PG; prostaglandin; PGI2; prostacyclin or prostaglandin I2; cPGI2; carbaprostacyclin; LTB4; leukotriene B4; 15dPGJ2; 15deoxyΔ12,14PGJ2; NO; nitric oxide; TBARS; thiobarb

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Inactivation of lipoprotein lipase occurs on the surface of THP-1 macrophages where oligomers of angiopoietin-like protein 4 are formed

Keywords: ANGPTL4; angiopoietin-like protein 4; BSA; bovine serum albumin; COX-2; cyclooxygenase-2; DMSO; dimethylsolfoxide; LPL; lipoprotein lipase; PBS; phosphate-buffered saline; 10 mM phosphate; 0.15 M NaCl, pH 7.4; PMA; phorbol 12-myristate 13-acetate; PPAR;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

PPARβ/δ atenúa la respuesta inflamatoria inducida por lípidos en el corazón a través de un mecanismo de transrepresión por antagonismo de receptores

Keywords: Corazón; GW501516; PPARβ/δ; Inflamación; NF-κBHeart; GW501516; PPARβ/δ; Inflammation; NF-κB

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Discovery, design and synthesis of Y-shaped peroxisome proliferator-activated receptor δ agonists as potent anti-obesity agents in vivo

Keywords: PPARδ; Nuclear receptors; Marine natural products; Anti-obesity; GW501516

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

The PPARδ agonist, GW501516, promotes fatty acid oxidation but has no direct effect on glucose utilisation or insulin sensitivity in rat L6 skeletal muscle cells

Keywords: PPAR, peroxisome proliferator-activated receptor; PGC-1α, peroxisome proliferator-activated receptor-gamma coactivator 1α; CPT-1, carnitine palmitoyl-transferase-1; GW, GW501516PPARβ/δ; GW501516; Glucose; Insulin; Metabolism

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARδ agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet

Keywords: Methionine-choline-deficient diet; NASH; Bezafibrate; PPAR; GW501516; (Mouse)

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

A highly efficient synthesis of antiobestic ligand GW501516 for the peroxisome proliferator-activated receptor δ through in situ protection of the phenol group by reaction with a Grignard reagent

Keywords: PPARδ; Antiobestic drug; GW501516; Grignard reagent; One-pot synthesis; Sulfide;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2005 سفارش ترجمه