Keywords: H1R; histamine H1 receptor; H2R; histamine H2 receptor; MC; mast cell; MCAD; mast cell activation disease; MCAS; mast cell activation syndrome; MMP; matrix metalloproteinase; NE; norepinephrine; SM; systemic mastocytosis;
مقالات ISI (ترجمه نشده)
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Assessing GPCR homology models constructed from templates of various transmembrane sequence identities: Binding mode prediction and docking enrichment
Keywords: A2AAR; adenosine receptor A2A; AUC; area under curve; β2AR; beta 2 adrenergic receptor; D3R; dopamine receptor D3; δOR; delta-opioid receptor; ECL; extracellular loop; GPCR; G protein-coupled receptor; H1R; histamine receptor H1; ICL; intracellular loop
Histamine H1 and H4 receptor expression on the ocular surface of patients with chronic allergic conjunctival diseases
Keywords: Atopic keratoconjunctivitis; Histamine receptor; Ocular surface; Real-time RT-PCR; Vernal keratoconjunctivitis; ACD; allergic conjunctival diseases; AC; allergic conjunctivitis; AKC; atopic keratoconjunctivitis; ECP; eosinophil cationic protein; H1R; Hist
The dual-acting AChE inhibitor and H3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats
Keywords: AChE; acetylcholine esterase; BChE; butyrylcholinesterase; AChEI; acetylcholine esterase inhibitor; H3R; histamine H3 receptor; H1R; histamine H1 receptor; H2R; histamine H2 receptor; AD; Alzheimer's disease; SCO; scopolamine; NMDA; N-methyl-d-aspartate;
BRET-based β-arrestin2 recruitment to the histamine H1 receptor for investigating antihistamine binding kinetics
Keywords: H1R; histamine H1 receptor; GPCR; G protein-coupled receptor; NFAT; nuclear factor of activated T-cells; ERK; extracellular signal-regulated kinases; BRET; bioluminescence resonance energy transfer; HEK293T; Human embryonic kidney cells transformed with l
Astemizole-Histamine induces Beclin-1-independent autophagy by targeting p53-dependent crosstalk between autophagy and apoptosis
Keywords: AST; Astemizole; HIS; Histamine; H1R; Histamine H1 receptor; ROS; Reactive oxygen species; ER; Endoplasmic reticulum; PERK; Protein kinase R-like endoplasmic reticulum kinase; IRE1α; Inositol-requiring enzyme 1; ATF; Activating transcription factor; JNK;
Epidermal growth factor receptor inhibitor cancer drug gefitinib modulates cell growth and differentiation of acute myeloid leukemia cells via histamine receptors
Keywords: 4-MH; 4-methylhistamine; AML; acute myelogenous leukemia; CML; chronic myelogenous leukemia; cAMP; cyclic adenosine monophosphate; CRE; cAMP response element; EGFR; epidermal growth factor receptor; ER; estrogen receptor alpha; FSK; Forskolin; GPCR; G-pro
Red ginseng extract blocks histamine-dependent itch by inhibition of H1R/TRPV1 pathway in sensory neurons
Keywords: H1R; histamine; itch; Korean Red Ginseng extract; TRPV1
Doxepin and diphenhydramine increased non-rapid eye movement sleep through blockade of histamine H1 receptors
Keywords: 5-HT; serotonin; EEG; electroencephalogram; EMG; electromyogram; H1R; histamine H1 receptor; KO; knockout; NREM; non-rapid eye movement; OTC; over-the-counter; REM; rapid eye movement; WT; wild type; H1 receptor; Knockout mice; NREM sleep; Wakefulness;
Betahistine co-treatment ameliorates dyslipidemia induced by chronic olanzapine treatment in rats through modulation of hepatic AMPKα-SREBP-1 and PPARα-dependent pathways
Keywords: ACC1; acetyl-CoA carboxylase 1; AMPKα; AMP-activated protein kinaseα; CPT1A; carnitine palmitoyltransferase 1A; FASN; fatty acid synthetase; H1R; histamine H1 receptors; H3R; histamine H3 receptors; HDL-C; high density lipoprotein cholesterol; HMGCoA; 3
Usefulness of HeLa cells to evaluate inverse agonistic activity of antihistamines
Keywords: GAPDH; glyceraldehyde-3-phosphate dehydrogenase; H1R; histamine H1 receptor; IPs; Inositol phosphates; PKCδ; protein kinase C δ; PMA; phorbol 12-myristate 13-acetate; RT-PCR; reverse transcription-polymerase chain reaction; TCA; trichloroacetic acid; Al
Quercetin inhibits transcriptional up-regulation of histamine H1 receptor via suppressing protein kinase C-δ/extracellular signal-regulated kinase/poly(ADP-ribose) polymerase-1 signaling pathway in HeLa cells
Keywords: BSA; bovine serum albumin; ERK; extracellular signal-regulated kinase; FBS; fetal bovine serum; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; H1R; histamine H1 receptor; IL; interleukin; IPs; inositol phosphates; PKCδ; protein kinase C δ; PMA; phorbo
Emerging opportunities for allosteric modulation of G-protein coupled receptors
Keywords: GPCR; G-protein coupled receptor; Ã2-AR; Ã2-adrenoceptor; Ã1-AR; Ã1-adrenoceptor; A2a-AR; A2a- adenosine receptor; CXCR4; CXCR4 chemokine receptor; D3R; dopamine 3 receptor; H1R; histamine 1 receptor; M2R; M2 muscarinic receptor; M3R; M3 muscarinic re
A report on anti-oedemogenic activity of Byttneria herbacea roots - Possible involvement of histamine receptor (type I)
Keywords: HBH; hydroalcoholic root extract of Byttneria herbacea; H1R; human histamine receptor type I; VEGF; vascular endothelial growth factor; LPS; lipopolysaccharide; HepG2; human hepatocellular liver carcinoma cell line; MTT; 3(4,5-dimethylthiazol-2-yl)-2,5-di
Ligand based design of novel histamine H4 receptor antagonists; fragment optimization and analysis of binding kinetics
Keywords: Histamine; H4R antagonist; GPCR; Binding kinetics; Fragment optimization; GPCRs; G protein-coupled receptors; H1R; histamine H1 receptor; H2R; histamine H2 receptor; H3R; histamine H3 receptor; H4R; histamine H4 receptor; SAR; structure-activity relatio
Mast cell degranulation mediates compound 48/80-induced hyperalgesia in mice
Keywords: WT; wild-type; c48/80; compound 48/80; MPO; myeloperoxidase; H1R; histamine receptor 1; H3/4R; histamine receptor 3/4; SCG; sodium cromoglycate; Mast cell; Compound 48/80; Histamine; Hyperalgesia; Neutrophil;
Transcriptional microarray analysis reveals suppression of histamine signaling by Kujin alleviates allergic symptoms through down-regulation of FAT10 expression
Keywords: H1R; histamine H1 receptor; TDI; toluene 2,4-diisocyanate; NF-κB; nuclear factor-kappa B; Allergic rhinitis; Kujin; FAT10; Histamine H1 receptor; Microarray analysis; NF-κB; Transcription;
Albizia lebbeck suppresses histamine signaling by the inhibition of histamine H1 receptor and histidine decarboxylase gene transcriptions
Keywords: AL; Albizia lebbeck; BCA; bicinchoninic acid; BSA; bovine serum albumin; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; HPLC; high-performance liquid chromatography; H1R; histamine H1 receptor; HDC; histidine decarboxylase; RT-PCR; reverse transcription
Histamine differentially regulates the production of Th1 and Th2 chemokines by keratinocytes through histamine H1 receptor
Keywords: Histamine; H1R; Th1; Th2; Keratinocytes;
Immune deficiencies, infection, and systemic immune disordersClemastine causes immune suppression through inhibition of extracellular signal-regulated kinase-dependent proinflammatory cytokines
Keywords: Antihistamine; bacterial infections; immune suppression; innate immunity; cytokines; signal transduction; sepsis; CFUs; Colony-forming units; ERK; Extracellular signal-regulated kinase; H1R; Histamine-1-receptor; IκB; Inhibitor of NF-kB; LM; Listeria mon
Histamine H1 and H2 receptors but not H4 receptors are upregulated during bone marrow regeneration
Keywords: Bone marrow; Regeneration; HDC; Histamine receptor; H1R; H2R; H4R; Gene expression
Histamine H1 receptor antagonist blocks histamine-induced proinflammatory cytokine production through inhibition of Ca2+-dependent protein kinase C, Raf/MEK/ERK and IKK/IκB/NF-κB signal cascades
Keywords: H1R; histamine H1 receptor; RT-PCR; reverse transcription-polymerase chain reaction; GM-CSF; granulocyte-macrophage-colony stimulating factor; IL; interleukin; olopatadine; olopatadine hydrochloride; PKC; protein kinase C; MEK; mitogen-activated protein/e