دانلود مقالات ISI درباره تبر + ترجمه فارسی

ترکیبات چندتایی که مویرهای ساختاری و عملکردی تاکرین و دونپزیل را دارند، برای درمان بالقوه بیماری آلزایمر

Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease

Keywords: تبر; ACh; acetylcholine; ChEs; cholinesterases; AChE; acetylcholinesterase; EeAChE; AChE from Electrophorus electricus; hAChE; human acetylcholinesterase; BuChE; butyrylcholinesterase; eqBuChE; BChE from equine serum; ChEI; ChE inhibitor; AChEI; AChE inhibitor

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

پادزهر آلوکسیم کواترنری و ثانویه برای قرار گرفتن در معرض ارگانوفسفره در یک سیستم مدل زبرا ماهی

Quaternary and tertiary aldoxime antidotes for organophosphate exposure in a zebrafish model system

Keywords: تبر; AChE; acetylcholinesterase; hAChE; human acetylcholinesterase; zAChE; zebrafish acetylcholinesterase; ATCh; acetylthiocholine; BBB; blood-brain barrier; BSA; bovine serum albumin; CPO; chlorpyrifos oxon; DDVP; dichlorvos; DTNB; 5,5′-dithiobis-(2-nitro

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Metal-involved theranostics: An emerging strategy for fighting Alzheimer's disease

Keywords: تبر; 3,4Apy; 3,4-diaminopyridine; 4Apy; 4-aminopyridine; AChE; acetylcholinesterase; AD; Alzheimer's disease; AFM; atomic force microscopy; APP; amyloid precursor protein; Aβ; amyloid-β peptide; BBB; blood brain barrier; bpy; 2,2-bipyridine; BSA; bovine se

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Mass spectral characterization of tabun-labeled lysine biomarkers in albumin

Keywords: تبر; AChE; acetylcholinesterase; u; unified atomic mass unit; hAChE; human AChE; HCD; high-energy collision-induced dissociation; HPLC; high performance liquid chromatography; LD50; median lethal dose; MS/MS; tandem mass spectrometry fragmentation; MWCO; molec

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Conjugates of salicylaldoximes and peripheral site ligands: Novel efficient nonquaternary reactivators for nerve agent-inhibited acetylcholinesterase

Keywords: تبر; OP; organophosphate; hAChE; human acetylcholinesterase; ACh; acetylcholine; 2-PAM; pralidoxime; MINA; monoisonitrosoacetone; BBB; bloodbrain barrier; CNS; central nervous system; P-site; peripheral anionic site; PSL; peripheral site ligand; TIQ; tetrahydr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Discorhabdin alkaloids from Antarctic Latrunculia spp. sponges as a new class of cholinesterase inhibitors

Keywords: تبر; Acetylcholinesterase inhibitor; Alzheimer's disease; Antarctic sponges; Discorhabdins; Molecular docking; Sponge metabolites; AChE; acetylcholinesterase; BChE; butyrylcholinesterase; eeAChE; electric eel acetylcholinesterase; ESI-MS; electrospray ionisati

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Aryl methylcarbamates: Potency and selectivity towards wild-type and carbamate-insensitive (G119S) Anopheles gambiae acetylcholinesterase, and toxicity to G3 strain An. gambiae

Keywords: تبر; aa; amino acid; AChE; acetylcholinesterase; AgAChE; Anopheles gambiae AChE; ATCh; acetylthiocholine; hAChE; human AChE; hmg; homogenate; IRS; indoor residual spraying; ITN; insecticide-treated net; PSA; polar surface area; Acetylcholinesterase; Anopheles

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Synthesis, biological activity and molecular modeling studies on 1H-benzimidazole derivatives as acetylcholinesterase inhibitors

Keywords: تبر; AChE; acetylcholinesterase; BuChE; butyrylcholinesterase; AD; Alzheimer's disease; AChEI; acetylcholinesterase inhibitors; Aβ; β-amyloid; PAS; peripheral anionic site; eeAChE; Electrophorus electricus AChE; TcAChE; Torpedo californica AChE; hAChE; hum

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Synthesis, pharmacological assessment, and molecular modeling of 6-chloro-pyridonepezils: New dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease

Keywords: تبر; hAChE; hBuChE; Dual AChE inhibitors; 6-Chloro-pyridonepezils; In vitro blood brain barrier; Molecular modeling; ADME; Alzheimer's disease

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Pyridonepezils, new dual AChE inhibitors as potential drugs for the treatment of Alzheimer's disease: Synthesis, biological assessment, and molecular modeling

Keywords: تبر; Pyridonepezils; hAChE; hBuChE; Dual AChE inhibitors; In vitro blood brain barrier; Molecular modeling; ADME; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9,10,11,12-tetrahydro-7H-benzo[7,8]chromeno[2,3-b]quinolin-8-amines as potential drugs for the treatment of Alzheimer's disease

Keywords: تبر; 7-Aryl-9,10,11,12-tetrahydro-7H-benzo[7,8]chromeno[2,3-b]quinolin-8-amines; hAChE; hBuChE; Kinetic analysis; Inhibition mechanism; Antioxidant; ORAC; Neuroprotection; Toxicity; Molecular modeling; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Peripheral site ligand conjugation to a non-quaternary oxime enhances reactivation of nerve agent-inhibited human acetylcholinesterase

Keywords: تبر; AChE; acetylcholinesterase; ACh; acetylcholine; ACN; acetonitrile; AmONO; isomamylnitrite; A-Site; active site; BBB; blood brain barrier; CNS; central nervous system; DCE; dichloroethane; DCM; dichloromethane; DMF; dimethylformamide; EtOAc; ethylacetate;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds

Keywords: تبر; Alzheimer; Multi-target; hAChE; BACE1

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Expression of the α7, α4 and α3 nicotinic receptor subtype in the brain and adrenal medulla of transgenic mice carrying genes coding for human AChE and β-amyloid

Keywords: تبر; Aβ; β-amyloid; AD; Alzheimer's disease; APPSWE; human amyloid precursor protein Swedish mutation; hAChE; AChE-enzyme; 125I-αBTX; 125I-αbungarotoxin; nAChRs; nicotinic acetylcholine receptors; Alzheimer's disease; Transgenic mice; Adrenal medulla; Cere

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه