G-CSF attenuates noise-induced hearing loss
Keywords: سلول مو; G-CSF; Cochlea; Hair cell; Hearing loss; Noise induced hearing loss
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Effects of substance P during the recovery of hearing function after noise-induced hearing loss
Keywords: سلول مو; Substance P; NK-1; Synaptic ribbon; Noise-induced hearing loss; Cochlea; Hair cell
Pitpnm1 is expressed in hair cells during development but is not required for hearing
Keywords: سلول مو; ABR; auditory brain stem response; ANOVA; analysis of variance; E; embryonic day; EDTA; ethylenediaminetetraacetic acid; P; postnatal day; PCR; polymerase chain reaction; Pitpnm1; inner ear; hair cell; mouse mutant; deafness; Mir96;
Otospheres derived from neonatal mouse cochleae retain the progenitor cell phenotype after ex vivo expansions
Keywords: سلول مو; ICR; Institute of Cancer Research; DMEM; Dullbecco's modified Eagle medium; DAPI; 4', 6-diamidino-2-phenyliodole; iPS cells; induced pluripotent stem cells; ES cells; embryonic stem cells; RT-PCR; reverse transcriptase-polymerase chain reaction; SE; sen
Basic NeuroscienceRNAlater facilitates microdissection of sensory cell-enriched samples from the mouse cochlea for transcriptional analyses
Keywords: سلول مو; OHC; outer hair cell; IHC; inner hair cell; RIN; RNA Integrity Number; ABR; auditory brainstem response; Hair cell; Cochlea; Method; Dissection; Mouse; RNA; RNAlater;
Regeneration of mammalian cochlear and vestibular hair cells through Hes1/Hes5 modulation with siRNA
Keywords: سلول مو; Hair cell regeneration; Inner ear; Notch pathway; siRNA; Nanoparticle; Mouse; GFP; green fluorescent protein; HC; hair cell; Hes1 and Hes5; hairy and enhancer of split 1 and 5; 4-HNE; 4-hydroxy-2-nonenal; NP; nanoparticle; OC; the organ of Corti; PLGA; po
The Genetic-Induced Hearing Loss Can Block the Effect of Noise Trauma in Waltzing Guinea pig
Keywords: سلول مو; Sensitivity; auditory evoked potential response; hair cell; morphology; hearing loss; waltzing guinea pig; postnatal
Coupling the cell cycle to development and regeneration of the inner ear
Keywords: سلول مو; Hair cell; Supporting cell; Proliferation; Regeneration; Cell cycle; Apoptosis; Cochlea; Vestibular organs
A balance of form and function: Planar polarity and development of the vestibular maculae
Keywords: سلول مو; Planar polarity; PCP; Vestibular; Utricle; Saccule; Hair cell; Stereocilia; Kinocilium
Notch signaling during cell fate determination in the inner ear
Keywords: سلول مو; Notch; Inner ear; Hair cell; Cochlea; Otic vesicle; Jagged
Wnt signaling during cochlear development
Keywords: سلول مو; Wnt; PCP; Cochlea; β-Catenin; Hair cell; RetinabHLH, basic helix-loop-helix; FGF, fibroblast growth factors; PCP, planar cell polarity; OEP, otic-epibranchial placode; Fzd, Frizzled receptor; E, embryonic day
Making connections in the inner ear: Recent insights into the development of spiral ganglion neurons and their connectivity with sensory hair cells
Keywords: سلول مو; Spiral ganglion; Cochlea; Afferent; Hair cell; Auditory; Deafness
The role of Atonal transcription factors in the development of mechanosensitive cells
Keywords: سلول مو; Atonal; bHLH; Transcription factor; Cilia; Hair cell; Regeneration; Inner ear; Mechanosensation; Cochlea; Sensory neuron
The large conductance calcium-activated K+ channel interacts with the small GTPase Rab11b
Keywords: سلول مو; Ion channels; BK channel; Rab family; Protein-protein interactions; Cochlea; Hair cell; Ganglion cell;
FMRFamide-related peptide expression in the vestibular-afferent neurons
Keywords: سلول مو; RF-amide; Semicircular canal; Hair cell; ASIC; Amiloride; Afferent synapse;
Transient receptor potential N (TRPN1) from Xenopus interacts with the penta-EF-hand protein peflin
Keywords: سلول مو; ANK; ankyrin; GST; glutathione-S-transferase; NHB; N-terminal hydrophobic; PEF; penta-EF-hand; TRP; transient receptor potential; TRPN1; Peflin; PEF; Mechanotransduction; Hair cell; TRP channel;
Micellization of cisplatin (NC-6004) reduces its ototoxicity in guinea pigs
Keywords: سلول مو; Auditory brainstem response; Cisplatin; Guinea pig; Hair cell; Polymeric micelle; Ototoxicity
Role of PGE-type receptor 4 in auditory function and noise-induced hearing loss in mice
Keywords: سلول مو; Cochlea; Hair cell; Hearing loss; Noise trauma; PGE-type receptor; DAPI; 4â²,6-diamino-2-phenyl-indole; ABR; auditory brainstem response; EP; E-prostanoid receptors; PGE2; prostaglandin E2; PGs; prostaglandins; ANOVA; analysis of variance; DMSO; dimethyl
Research paperMorphological and morphometric characteristics of vestibular hair cells and support cells in long term cultures of rat utricle explants
Keywords: سلول مو; AIC; Akaike's information criterion; ANOVA; analysis of variance; BDNF; brain-derived neurotrophic factor; DIV; days in vitro; FITC; fluorescein isothiocyanate; HC; hair cell; IGF-1; insulin-like growth factor type one; LM; light microscopy; P4; 4-day-
Otoferlin: a multi-C2 domain protein essential for hearing
Keywords: سلول مو; hair cell; calcium; priming; fusion; synaptic vesicle; ferlins;
Evaluation of the chemical model of vestibular lesions induced by arsanilate in rats
Keywords: سلول مو; Arsanilate; Vestibular system; Sense organ; Syndrome; Hair cell; Labyrinthectomy
Molecular anatomy and physiology of exocytosis in sensory hair cells
Keywords: سلول مو; Hair cell; Exocytosis; Synaptic ribbon; Hearing; Calcium; Synaptic protein; Synaptic vesicle; Pool; Ribeye; Active zone; Neurotransmission;
Fgf signaling regulates development and transdifferentiation of hair cells and supporting cells in the basilar papilla
Keywords: سلول مو; BP; Basilar papilla; HC; Hair cell; SC; Supporting cell; PC; Progenitor cell; DIV; Days in vitro;
TFE2 and GATA3 enhance induction of POU4F3 and myosin VIIa positive cells in nonsensory cochlear epithelium by ATOH1
Keywords: سلول مو; ATOH1; combinatorial code; TFE2; GATA3; hair cell; POU4F3
N-Myc and L-Myc are essential for hair cell formation but not maintenance
Keywords: سلول مو; L-Myc; N-Myc; Hair Cell; Hearing; Prevention; Regeneration;
Mathematical modeling and simulation of biologically inspired hair receptor arrays in laminar unsteady flow separation
Keywords: سلول مو; Micro air vehicles; Bats; Hair cell; Micropillars; Microcantilevers; Cilia
Ribeye a-mCherry fusion protein: A novel tool for labeling synaptic ribbons of the hair cell
Keywords: سلول مو; Balance; Hair cell; Hearing; Transgenic; Zebrafish;
Hydrogen in drinking water attenuates noise-induced hearing loss in guinea pigs
Keywords: سلول مو; Temporary threshold shift; Oxidative stress; Cochlea; Hair cell
Sox2 and Fgf interact with Atoh1 to promote sensory competence throughout the zebrafish inner ear
Keywords: سلول مو; Zebrafish; atoh1a/b; sox2; fgf3; fgf8; Hair cell; Support cell; Heat shock;
Expression of vesicular glutamate transporters in peripheral vestibular structures and vestibular nuclear complex of rat
Keywords: سلول مو; vesicular glutamate transporter; hair cell; ganglionectomy; vestibular nucleus; immunohistochemistry; rat; As; stalk of the ampullary crest; DRG; dorsal root ganglion; g7; genu of facial nerve; icp; inferior cerebellar peduncle; LVe; lateral vestibular nu
Matrix metalloproteinases 2 and 9 in the cochlea: expression and activity after aminoglycoside exposition
Keywords: سلول مو; apoptosis; extracellular matrix; hair cell; inner ear; retinaB, brain; BCA, bicinchoninic acid; bp, base pairs; BSA, bovine serum albumin; cDNA, complementary deoxyribonucleic acid; CNFs, cochlear nerve fibers; DAPI, 4′,6-diamidino-2-phenylindole; DNase,
Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development
Keywords: سلول مو; Hair cell; Supporting cell; Hes1; Hes5; Hey1; Developing cochlea;
Rbpj regulates development of prosensory cells in the mammalian inner ear
Keywords: سلول مو; Hair cell; Notch; Prosensory cell; Cochlea; Saccule;
Non-cell-autonomous planar cell polarity propagation in the auditory sensory epithelium of vertebrates
Keywords: سلول مو; Vangl2; PCP; Wnt5a; Avian; Inner ear; Hair cell; Stereocilia
Regulation of POU4F3 gene expression in hair cells by 5â² DNA in mice
Keywords: سلول مو; autoregulation; gene expression; hair cell; POU4F3; ATOH1; bioinformatics; β-Gal; beta-galactosidase; bHLH; basic helix-loop-helix; ChIP; chromatin immunoprecipitation; eGFP; enhanced green fluorescent protein; HC; hair cells; oC; organ of Corti; PCR; po
The influences of sphingolipid metabolites on gentamicin-induced hair cell loss of the rat cochlea
Keywords: سلول مو; Sphingolipid; Ceramide; Sphingosine 1-phosphate (S1P); Ganglioside; Gentamicin; Hair cell; Organ of Corti
Age-related loss of spiral ganglion neurons
Keywords: سلول مو; Spiral ganglion neuron; Hair cell; Neural presbycusis; Aging; Glucocorticoid; Caloric restriction; CalciumSGNs, spiral ganglion neurons; IGF-1, insulin-like growth factor-1; CR, caloric restriction; ROS, reactive oxygen species; NFκB, nuclear factor-κB; O
The progenitors of inner ear hair cells and their regulating genes
Keywords: سلول مو; Hair cell; Regeneration; Progenitor cell; Inner ear;
Use of the biodegradable polymer chitosan as a vehicle for applying drugs to the inner ear
Keywords: سلول مو; Round window membrane; Chitosan; Hair cell; Drug delivery
The influence of acoustic and static stimuli on development of inner ear sensory epithelia
Keywords: سلول مو; Inner ear; Hair cell; Mechanical stimuli; Mouse development
Hair cell fate decisions in cochlear development and regeneration
Keywords: سلول مو; Cochlea; Hair cell; Supporting cell; Genetic regulation; Notch pathway; Development; Regeneration
Sox2 is required for maintenance and regeneration, but not initial development, of hair cells in the zebrafish inner ear
Keywords: سلول مو; Regeneration; Hair cell; Support cell; Zebrafish; Heat shock; Atoh1a; Fgf; Notch; Laser ablation
Estradiol protects the cochlea against gentamicin ototoxicity through inhibition of the JNK pathway
Keywords: سلول مو; Gentamicin; c-jun N-terminal kinase (JNK); 17β-Estradiol (E2); Hair cell; Organ of Corti
Phosphatase and tensin homolog deleted on chromosome 10 regulates sensory cell proliferation and differentiation of hair bundles in the mammalian cochlea
Keywords: سلول مو; PTEN; hair cell; stereocilia; proliferation; differentiationBrdU, 5-bromodeoxyuridine; BSA, bovine serum albumin; CNS, central nervous system; DAPI, 4,6-diamino-2-phenylindole; E, embryonic day; EDTA, ethylenediaminetetraacetic acid; FITC, fluorescein iso
Emx2 and early hair cell development in the mouse inner ear
Keywords: سلول مو; Emx2; Planar cell polarity; Hair cell; Inner ear; Striola;
Time sequence of auditory nerve and spiral ganglion cell degeneration following chronic kanamycin-induced deafness in the guinea pig
Keywords: سلول مو; SGC, spiral ganglion cell; IHC, inner hair cell; OHC, outer hair cell; AN, auditory nerve; VG, vestibular ganglion; BDNF, brain-derived neurotrophic factorOtotoxicity; Spiral ganglion cell; Hair cell; Auditory nerve; Schwann cell
Cell cycle regulation in the inner ear sensory epithelia: Role of cyclin D1 and cyclin-dependent kinase inhibitors
Keywords: سلول مو; Inner ear; Hair cell; Supporting cell; Postmitotic; Cell cycle re-entry; Proliferation; Therapy; Cyclin D1; Cyclin-dependent kinase inhibitor; β-catenin;
Future approaches for inner ear protection and repair
Keywords: سلول مو; Deafness; Hair cell; Spiral ganglion; Gene therapy; Regeneration; Protection; Neurotrophin
Effect of c-myc on the ultrastructural structure of cochleae in guinea pigs with noise induced hearing loss
Keywords: سلول مو; c-myc; Ultrastructural structure; Hair cell; Noise
Prostaglandin E receptor subtype EP4 agonist protects cochleae against noise-induced trauma
Keywords: سلول مو; acoustic trauma; hair cell; hearing loss; inner ear; prostanoidABR, auditory brain-stem response; bp, base pairs; cAMP, cyclic AMP; DMSO, dimethyl sulfoxide; EDTA, ethylenediamine tetra-acetic acid; EP, prostaglandin E receptor subtype; HC, hair cell; HGF