دانلود مقالات ISI درباره Hbss + ترجمه فارسی

Structural properties for selective and efficient l-type amino acid transporter 1 (LAT1) mediated cellular uptake

Keywords: ARPE-19; a human retinal pigment epithelial cell line; ATCC; American Type Culture Collection; ASCT2; alanine-serine-cysteine transporter 2; BBB; Blood Brain Barrier; BCH; 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid; CNS; Central Nervous System; CYP3

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Paraptosis in human glioblastoma cell line induced by curcumin

Keywords: Cell Death; Paraptosis; Curcumin; Endoplasmic Reticulum Stress Response; miRNAs; AKT; Serine-threonine kinase; ATF6; Activating transcription factor 6; BCL2; B- Cell lymphoma 2; BIP; Immunoglobulin-heavy-chain binding protein; CHOP; C/EBPhomologous protei

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

The role of the ATPase inhibitor factor 1 (IF1) in cancer cells adaptation to hypoxia and anoxia

Keywords: ΔμH+;  proton electrochemical potential, proton motive force; Δψm; mitochondrial membrane potential; F1F0-ATPase; ATP synthase; IF1; endogenous inhibitor protein of the mitochondrial F1F0-ATPase; ANT; adenine nucleotide translocator; CS; citrate synt

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Mitochondrial tRNALeu(UUR) C3275T, tRNAGln T4363C and tRNALys A8343G mutations may be associated with PCOS and metabolic syndrome

Keywords: PCOS; polycystic ovary syndrome; T2DM; type 2 diabetes mellitus; MetS; metabolic syndrome; mtDNA; mitochondrial DNA; TG; triglyceride; HbA1c; Hemoglobin A1c; MMP; mitochondrial membrane potential; ROS; reactive oxygen species; PMNs; polymononuclear leukoc

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Evaluation of drug permeation under fed state conditions using mucus-covered Caco-2 cell epithelium

Keywords: BM; biosimilar mucus; C10; sodium caprate; C12; sodium laurate; NaTC; sodium taurocholate; PC; phosphatidylcholine; MO; monoolein; OA; oleic acid; TEER; transepithelial electrical resistance; HBSS; Hank's Balanced Salt Solution; PAA; polyacrylic acid; FeS

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

A constitutively-active IKK-complex at the axon initial segment

Keywords: Axon initial segment; NF-κB; IKK 2 Kinase; Ankyrin-G; Proximity ligation assay; Axon; AIS; axon initial segment; ASA; acetyl-salicylic acid; DMEM; Dulbecco's modified Eagle media; eGFP; enhanced green-fluorescent protein; FADD; Fas-associated death dom

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Extra collagen overlay prolongs the differentiated phenotype in sandwich-cultured rat hepatocytes

Keywords: Bile canaliculi; Collagen; Hepatic drug disposition; Methods; Sandwich-cultured rat hepatocytes; AUC; Area Under the Curve; BEI; biliary excretion index; CDF; 5-(6)-carboxy-2-dichlorofluorescein; CDFDA; 5-(6)-carboxy-2-dichlorofluorescein diacetate; Clint

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Impaired oligodendrogenesis and myelination by elevated S100B levels during neurodevelopment

Keywords: Inflammatory injury; Neurodevelopment; Oligodendrogenesis; Receptor for advanced glycation end-products; S100B protein; BSA; Bovine serum albumin; CNS; Central nervous system; CSF; Cerebrospinal fluid; OCSC; Organotypic cerebellar slice cultures; DIV; Day

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Similarities and differences in surface receptor expression by THP-1 monocytes and differentiated macrophages polarized using seven different conditioning regimens

Keywords: BV; Brilliant Violet; CD; Cluster of Differentiation; CLEC; C-type lectin receptor; EDTA; Ethylenediaminetetraacetic acid; FCS; Fetal calf serum; FSC-A; Forward Scatter; HBSS; Hank's Balanced Salt Solution; IFN; Interferon; LPS; Lipopolysaccharide; PMA;

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Rescue of Fmr1KO phenotypes with mGluR5 inhibitors: MRZ-8456 versus AFQ-056

Keywords: mGluR5; Fmr1; MRZ-8456; AFQ-056; MPEP; Amyloid-beta precursor protein; Aβ; amyloid-beta; ABC-C; Aberrant Behavior Checklist-Community Edition; AGS; audiogenic-induced seizures; APP; amyloid-beta protein precursor; CNS; central nervous system; CTEP; 2-chl

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway

Keywords: ALT; alanine aminotransferase; AST; aspartate aminotransferase; CK; creatine kinase; CRC; colorectal cancer; CUHK; The Chinese University of Hong Kong; EMT; epithelial-mesenchymal transitions; FOLFIRI; FOL-folinic acid (leucovorin), F-fluorouracil (5-FU

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Kaempferol Inhibits Extra-synaptic NMDAR-Mediated Downregulation of TRkβ in Rat Hippocampus During Hypoxia

Keywords: DCFHDA; 2,7-dichlorofluorescein-diacetate; EDTA; ethylene diamine tetraacetate; GPx; glutathione peroxidase; HBSS; Hank's balanced salt solution; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; NMDARs; N-methyl-d-aspartate receptor; PBS; phos

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Lipid droplets induced by secreted phospholipase A2 and unsaturated fatty acids protect breast cancer cells from nutrient and lipotoxic stress

Keywords: AA; arachidonic acid; AMPK; AMP-dependent protein kinase; ATGL; adipose triglyceride lipase; cPLA2α; cytosolic group IVA PLA2; CPT1; carnitine O-palmitoyltransferase 1; CPT1A; the liver isoform of CPT1; DGAT1; diacylglycerol acyltransferase 1; DHA; docos

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

l-Cysteine suppresses hypoxia-ischemia injury in neonatal mice by reducing glial activation, promoting autophagic flux and mediating synaptic modification via H2S formation

Keywords: AOAA; aminooxyacetic acid; CBS; cystathionine β synthase; CD86; cluster of differentiation 86; CNS; central nervous system; DAPI; 4,6-diamidino-2-phenylindole; DAO; d-amino acid oxidase; GFAP; glial fibrillary acidic protein; HBSS; Hanks Balanced Salt So

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

Probing the binding site of novel selective positive allosteric modulators at the M1 muscarinic acetylcholine receptor

Keywords: ACh; acetylcholine; mAChR; muscarinic acetylcholine receptor; GPCR; G protein-coupled receptor; AD; Alzheimer's disease; PAM; positive allosteric modulator; NAM; negative allosteric modulator; TM; transmembrane domain; ECL; extracellular loop; CHO; Chin

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

Neutralization of TNFR-1 and TNFR-2 modulates S. aureus induced septic arthritis by regulating the levels of pro inflammatory and anti inflammatory cytokines during the progression of the disease

Keywords: ANOVA; analysis of variance; CFU; colony forming unit; CIA; collagen-induced arthritis; CPCSEA; committee for the purpose of control and supervision of experiments on animals; Cyt C; cytochrome C; DMSO; dimethyl sulfoxide; DPI; days post infection; EDTA;

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

The 3-phenylcoumarin derivative 6,7-dihydroxy-3-[3′,4′-methylenedioxyphenyl]-coumarin downmodulates the FcγR- and CR-mediated oxidative metabolism and elastase release in human neutrophils: Possible mechanisms underlying inhibition of the formation a

Keywords: ABAH; 4-aminobenzoic acid hydrazide; ANOVA; analysis of variance; CL-luc; lucigenin-enhanced chemiluminescence; CL-lum; luminol-enhanced chemiluminescence; CR; complement receptor; DAPI; 4',6-diamidino-2-phenylindole dihydrochloride; DMSO; dimethyl sulfox

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2018 سفارش ترجمه

NADPH oxidase activity: Spectrophotometric determination of superoxide using pyrogallol red

Keywords: NADPH oxidases; HL-60 cells; Neutrophil-like cells; Pyrogallol red; VAS2870; Diphenylene Iodonium; NOX; NADPH Oxidases; PGR; Pyrogallol Red; PMA; Phorbol 12-mirystate 13-acetate; DPI; Diphenyleneiodonium; HBSS; Hank's Balanced Salt Solution;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

CD4+ T cells support establishment of RSV-specific IgG and IgA antibody secreting cells in the upper and lower murine respiratory tract following RSV infection

Keywords: URT; upper respiratory tract; LRT; lower respiratory tract; RSV; respiratory syncytial virus; FI-RSV; formalin-inactivated RSV vaccine; FCS; fetal calf serum; ELISA; enzyme-linked immunosorbent assay; HBSS; hanks balanced salt solution; PBS; phosphate buf

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Involvement of intestinal efflux and metabolic instability in the pharmacokinetics of platycodin D in rats

Keywords: Platycodin D (PD); Absorption time; Intestinal first-pass effect; Limited intestinal permeability; Gastrointestinal metabolism; PD; platycodin D; DMSO; dimethyl sulfoxide; PEG; polyethylene glycol; Papp; apparent permeability coefficients; HBSS; Hank's ba

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Transport of soybean protein-derived antihypertensive peptide LSW across Caco-2 monolayers

Keywords: Antihypertensive peptide; Caco-2 cell; LSW; PepT1; Transport; ACN; acetonitrile; ACE; angiotensin-converting enzyme; AP; apical side; BL; basolateral side; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; LSW; Leu-Ser-Trp; IRW; Ile-A

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Valorization of the whole grains of Triticum aestivum L. and Triticum vulgare L. through the investigation of their biochemical composition and in vitro antioxidant, anti-inflammatory, anticancer and anticalpain activities

Keywords: Wheat species; Phytochemical composition; Antioxidant activities; Anti-calpain activity; EMEM; Eagle's Minimal Essential Medium.; FBS; Fetal Bovine Serum.; MTT; Methylthiazolyldiphenyl-tetrazolium bromide.; RRLC; Rapid Resolution Liquid Chromatography.;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

The F0F1 ATP synthase regulates human neutrophil migration through cytoplasmic proton extrusion coupled with ATP generation

Keywords: ATP; adenosine triphosphate; F-ATPase; F0F1-ATP synthase; fMLP; N-formyl-Met-Leu-Phe; ADP; adenosine diphosphate; BSA; bovine serum albumin; SDS; sodium dodecyl sulfate; PMSF; phenylmethane sulfonyl fluoride; TTFA; thenoyltrifluoroacetone; CCCP; carbonyl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Effects of fucoidans and heparin on reactions of neutrophils induced by IL-8 and C5a

Keywords: Fucoidan (PubChem CID: 92023653); Sodium Heparin (PubChem CID: 22833565); AUC; area under the curve; BSA; bovine serum albumin; C5a; complement component C5a; DS; degree of sulfation; D.s.-SP; sulfated polysaccharides of Delesseria sanguinea; EC50; half m

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperMucin dispersions as a model for the oromucosal mucus layer in in vitro and ex vivo buccal permeability studies of small molecules

Keywords: BSA; bovine serum albumin; HBSS; Hanks' balanced salt solution; HFDS; human freeze-dried saliva; Log P; logarithm of partition coefficient; Log D; logarithm of distribution coefficient; MW; molecular weight; Papp; apparent permeability coefficient; PBS;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Nogo-receptor 1 antagonization in combination with neurotrophin-4/5 is not superior to single factor treatment in promoting survival and morphological complexity of cultured dopaminergic neurons

Keywords: FFRT; free-floating roller tube; GDNF; glial cell line-derived neurotrophic factor; GFAP; glial fibrillary acidic protein; HBSS; Hank's balanced salt solution; HS; horse serum; LINGO-1; leucine rich repeat neuronal protein 1; MAP2; microtubule-associate

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Enhanced expression of Organic Cation Transporters in bronchial epithelial cell layers following insults associated with asthma - Impact on salbutamol transport

Keywords: ALI; air-liquid interface; AMC; 7-amino-4-methylcoumarin; BSA; bovine serum albumin; CCL17; chemokine (C-C motif) ligand 17; CCR3; C-C chemokine receptor 3; COX-2; cyclo-oxygenase 2; EDTA; ethylenediaminetetraacetic acid; HBSS; Hank's Balanced Salt Soluti

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperIn vitro uptake and transport studies of PEG-PLGA polymeric micelles in respiratory epithelial cells

Keywords: ANOVA; analysis of variance; CA; curcumin acetate; CPZ; chlorpromazine; HBSS; Hank's balanced salt solution; LY; Lucifer Yellow; MEM; minimum essential medium; mPEG; methoxypoly (ethylene glycol); MβCD; methyl-β-cyclodextrin; NR; Nile Red; Papp; appar

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Production and characterization of a PEGylated derivative of recombinant human deoxyribonuclease I for cystic fibrosis therapy

Keywords: AEC; anion-exchange chromatography; BSA; bovine serum albumin; CD; circular dichroism; CF; cystic fibrosis; HBSS; Hank's balanced salt solution; MALDI-TOF MS; matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; N-ter; N-terminal;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Releases from transparent blue automobile coatings containing nanoscale copper phthalocyanine and their effects on J774 A1 macrophages

Keywords: AUC; Analytical Ultracentrifuge; CNTs; carbon nanotubes; CPC; condensation particle counter; DCFHDA; carboxy-2′,7′-dichloro-dihydro-fluorescein diacetate; DMSO; dimethyl sulfoxide; Frag n-CuPc; Fragments of nanoscale Copper Phthalocyanine; Frag Refer;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Combination of ABT-737 and resveratrol enhances DNA damage and apoptosis in human T-cell acute lymphoblastic leukemia MOLT-4 cells

Keywords: T-ALL; T-cell acute lymphoblastic leukemia; RES; resveratrol; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma extra-large; Bcl-w; BCL-2-like protein 2; Bax; Bcl-2-associated X protein; Bak; Bcl-2-associated killer; Bad; Bcl-2-associated death promoter;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

MiR-23b controls TGF-β1 induced airway smooth muscle cell proliferation via direct targeting of Smad3

Keywords: MiR-23b; TGF-β1/Smad3; Asthma; Airway smooth muscle cells; ASMCs; airway smooth muscle cells; BSA; bovine serum albumin; DMEM; Dulbecco's modified Eagle's medium; Smad; drosophila mothers against decapentaplegic protein; FBS; fetal bovine serum; HBSS; Ha

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Inhibition of stress induced premature senescence in presenilin-1 mutated cells with water soluble Coenzyme Q10

Keywords: Aβ; amyloid-beta peptide; AD; Alzheimer's disease; APP; amyloid precursor protein; CoQ10; Coenzyme Q10; DCF; 2′,7′-dichlorofluorescein; DIC; differential interference contrast; H2DCFDA; 2′-7′-dichlorofluorescin diacetate; HBSS; Hank's Balanced Sa

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Passive transfer of interferon-γ over-expressing macrophages enhances resistance of SCID mice to Mycobacterium tuberculosis infection

Keywords: AMs; alveolar macrophages; NH4Cl; ammonium chloride; BAL; bronchoalveolar lavage; CFU; colony forming units; DiI; 1,1′-dioctadecyl-3,3,3′,3′ tetramethylindocarbocyanine perchlorate; DMEM; Dulbecco's minimum essential medium; EDTA; ethylenediaminet

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Potential anti-cancer activity of 7-O-pentyl quercetin: Efficient, membrane-targeted kinase inhibition and pro-oxidant effect

Keywords: Akt; protein kinase B (PKB); CK2; casein kinase 2; CsA; Cyclosporin A; DMEM; Dulbecco's Modified Eagle Medium; DTT; 1,4-Dithiothreitol; FBS; fetal bovine serum; GSK-3; glycogen synthase kinase 3; HBSS; Hank's Balanced Salt Solution; IKKα/β; IκB kin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperSurface modification of an intraocular lens material by plasma-assisted grafting with 2-hydroxyethyl methacrylate (HEMA), for controlled release of moxifloxacin

Keywords: AFM; Atomic Force Microscopy; ca.; circa; CEC; corneal endothelial cells; EWC; equilibrium water content; FBS; Fetal bovine serum; HBSS; Hank's balanced salt solution; HEMA; 2-Hydroxyethyl methacrylate; HPLC; high-performance liquid chromatography; IOL;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Induction of intrinsic apoptosis in leukaemia stem cells and in vivo zebrafish model by betulonic acid isolated from Walsura pinnata Hassk (Meliaceae)

Keywords: Leukaemia stem cells; Betulonic acid; Meliaceae; Apoptosis; Zebrafish; ALDH; aldehyde dehydrogenase; AML; acute myelogenous leukaemia; BA; betulonic acid; DMSO; dimethyl sulfoxide; DNA; deoxyribonucleic acid; FBS; foetal bovine serum; HBSS; Hanks Balanced

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Aronia (Aronia melanocarpa) phenolics bioavailability in a combined in vitro digestion/Caco-2 cell model is structure and colon region dependent

Keywords: SHIME®; Simulator of the human intestinal microbial ecosystem; HBSS; Hank's balanced salt solutions; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5 diphenyl tetrazolium bromide; SRB; sulforhodamine B; PBS; Phosphate buffered saline; TEER; transepithelial electr

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Chains of magnetosomes with controlled endotoxin release and partial tumor occupation induce full destruction of intracranial U87-Luc glioma in mice under the application of an alternating magnetic field

Keywords: GBM; glioblastoma; AMF; alternating magnetic field; IONP; iron oxide nanoparticles; CM; magnetosome chains; UV; irradiation of an ultraviolet lamp; LAL; limulus amebocyte lysate; DMEM; dulbecco's Modified Eagle Medium; FBS; fetal bovine serum; HBSS; hank'

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Improved synthesis and comparative analysis of the tool properties of new and existing D-ring modified (S)-blebbistatin analogs

Keywords: Blebbistatin; Myosin II; Photostability; Solubility; Cell membrane permeability; 2-mTHF; 2-methyltetrahydrofuran; A-B; apical-to-basolateral; B-A; basolateral-to-apical; CV; column volume; DMAP; 4-(dimethylamino)pyridine; DMEM; Dulbecco's modified Eagle m

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Effects of VPAC1 activation in nucleus ambiguus neurons

Keywords: [Ca2+]i; cytosolic Ca2+ concentration; HBSS; Hanks' balanced salt solution; IP3; inositol 1,4,5-trisphosphate; nAmb; nucleus ambiguus; PACAP; pituitary adenylyl cyclase-activating polypeptide; VIP; vasoactive intestinal polypeptide; Autonomic cardiac to

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Long noncoding RNA Malat1 is a potent autophagy inducer protecting brain microvascular endothelial cells against oxygen-glucose deprivation/reoxygenation-induced injury by sponging miR-26b and upregulating ULK2 expression

Keywords: BBB; blood-brain barrier; BMECs; brain microvascular endothelial cells; ceRNAs; competing endogenous RNAs; HBSS; Hanks' Balanced Salt Solution; HRP; horseradish peroxidase; I/R; ischemia-reperfusion; lncRNAs; long noncoding RNAs; ncRNAs; non-coding

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of Bile Acids Responsible for Inhibiting the Bile Salt Export Pump, Leading to Bile Acid Accumulation and Cell Toxicity in Rat Hepatocytes

Keywords: biliary excretion; in vitro models; toxicology; bile acid transporters; efflux pumps; BA; bile acid; BSEP; bile salt export pump; CA; cholic acid; CDCA; chenodeoxycholic acid; CsA; cyclosporin A; DCA; deoxycholic acid; DILI; drug-induced liver injury; DM

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

R- and S-Warfarin Were Transported by Breast Cancer Resistance Protein: From In Vitro to Pharmacokinetic-Pharmacodynamic Studies

Keywords: ABC transporters; drug transport; mass spectrometry; preclinical pharmacokinetics; pharmacokinetics/pharmacodynamics; INR; international normalized ratio; BCRP; breast cancer resistance protein; ABCG2; ATP-binding cassette transporter G2; CYP450; cytochro

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Deletion of CD73 in mice leads to aortic valve dysfunction

Keywords: ABTS; 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid); ADA; adenosine deaminase; ADP; adenosine diphosphate; ALP; alkaline phosphatase; AMP; adenosine monophosphate; AOPCP; α,β-Methylene-ADP; AS; aortic stenosis; ATP; adenosine triphosphate; A

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Understanding the Interplay Between Uptake and Efflux Transporters Within In Vitro Systems in Defining Hepatocellular Drug Concentrations

Keywords: hepatic clearance; hepatic transport; hepatobiliary disposition; hepatocytes; transporters; ABT; 1-aminobenzotriazole; Bcrp; breast cancer resistance protein; BDDCS; Biopharmaceutial Drug Disposition Classification System; BEI; biliary excretion index; Ca

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Selectivity of coronaridine congeners at nicotinic acetylcholine receptors and inhibitory activity on mouse medial habenula

Keywords: AChR; nicotinic acetylcholine receptor; ACh; acetylcholine; NCA; noncompetitive antagonist; RT; room temperature; MHb; medial habenula; VI; ventral inferior; Ki; inhibition constant; Kd; dissociation constant; IC50; ligand concentration that produces 50%

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Ipratropium is 'luminally recycled' by an inter-play between apical uptake and efflux transporters in Calu-3 bronchial epithelial cell layers

Keywords: a-b; apical to basolateral; ALI; air-liquid interface; b-a; basolateral to apical; FITC; fluorescein isothiocyanate; HBSS; Hank's Balanced Salt Solution; IPRL; isolated perfused rat lungs; MATE; multidrug and toxin extrusion transporters; MRP; Multidrug

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

In vivo fate of lipid-silybin conjugate nanoparticles: Implications on enhanced oral bioavailability

Keywords: Lipid-drug conjugate; Drug delivery; Oral; Silybin; Solid lipid nanoparticles; AP; apical; ATO 5; Precirol® ATO 5; BL; basolateral; CLSM; confocal laser scanning microscopy; DL; drug loading; DMEM; Dulbecco's Modified Eagle's Medium; EE; entrapment eff

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

Involvement of scavenger receptor class B type 1 and low-density lipoprotein receptor in the internalization of liposomes into HepG2 cells

Keywords: DMEM; Dulbecco's Modified Eagle's medium; EDTA; ethylenediaminetetraacetic acid; FBS; fetal bovine serum; HBSS; Hanks' balanced salt solution; HDL; high-density lipoprotein; HSPC; hydrogenated soy phosphatidylcholine; LDL; low-density lipoprotein receptor

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه