Inhibitory effects of tricin derivative from Sasa albo-marginata on replication of human cytomegalovirus
Keywords: Anti-cytomegalovirus activity; Tricin; HCMV; IE2; COX-2; Entry
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PPARγ and human trophoblast differentiation
Keywords: Placenta; Trophoblast invasion; hCG; hCMV; Preeclampsia
Multiple phosphorylation sites at the C-terminus regulate nuclear import of HCMV DNA polymerase processivity factor ppUL44
Keywords: HCMV; DNA polymerase; Processivity factor; Phosphorylation; Nuclear transport; Protein kinase CK2; Protein kinase CK1; Large tumor antigen; Regulation; Replication
Roles and regulation of microRNAs in cytomegalovirus infection
Keywords: Cytomegalovirus; MiRNA; Herpesvirus; HCMV; MCMV; RCMV
The enhanced host-cell permissiveness of human cytomegalovirus is mediated by the Ras signaling pathway
Keywords: DMEM; Dulbecco's Modified Eagle's Medium; E; Early; EBV; Epstein-Barr virus; EGF; Epidermal Growth Factor; EGFR; Epidermal Growth Factor Receptor; ERK; Extracellular Regulated Kinase; FBS; Fetal Bovine Serum; FTI; Farnesyl Transferase Inhibitor; HFF; Huma
Inhibition of mouse TAP by immune evasion molecules encoded by non-murine herpesviruses
Keywords: MHC I; MHC class I; TAP; transporter associated with antigen processing; ER; endoplasmic reticulum; HC; heavy chain; PLC; peptide-loading complex; HCMV; human cytomegalovirus; EBV; Epstein-Barr virus; BoHV-1; bovine herpesvirus 1; recVACV; recombinant v
High-content screening to distinguish between attachment and post-attachment steps of human cytomegalovirus entry into fibroblasts and epithelial cells
Keywords: HCMV; Cytomegalovirus; High-content screening; Imaging; Virus entry
Structural and functional analysis of the TAP-inhibiting UL49.5 proteins of varicelloviruses
Keywords: CTL; cytotoxic T lymphocyte; MHC I; major histocompatibility complex class I; TAP; transporter associated with antigen processing; ER; endoplasmic reticulum; HCMV; human cytomegalovirus; BoHV; bovine herpesvirus; gM; glycoprotein M; BuHV-1; bubaline herpe
Regulation of nucleocytoplasmic trafficking of viral proteins: An integral role in pathogenesis?
Keywords: BPV; bovine papillomavirus; BRAP2; BRCA1-associated protein 2; CAV; chicken anaemia virus; CBP; CREB binding protein; Cdk; cyclin dependent kinase; CK1; protein kinase CK1; CK2; protein kinase CK2; Crm1; chromosome region maintenance protein 1; CTD; C-ter
Virus-encoded microRNAs
Keywords: MicroRNA; miRNA; Polyomavirus; KSHV; EBV; HCMV; SV40; JCV; BKV; Herpesvirus;
Modifications of C-2 on the pyrroloquinoline template aimed at the development of potent herpesvirus antivirals with improved aqueous solubility
Keywords: Pyrroloquinoline; Cytomegalovirus; HCMV; Varicella-zoster; Herpesvirus
Herpesviruses: Hijacking the Ras signaling pathway
Keywords: BL; Burkitt's lymphoma; COX-2; cytochrome c oxidase subunit II; E; Early; EBNA; Epstein-Barr nuclear antigen; EBV; Epstein-Barr virus; EGF; Epidermal Growth Factor; EGFR; Epidermal Growth Factor Receptor; Elk; Ets-related transcription factor; ERK; ex
A new tool linking human cytomegalovirus drug resistance mutations to resistance phenotypes
Keywords: UL97; UL54; Genotype; Clinical outcome; HCMV; GCV; CDV; FOS
Scavenger receptor A1 is required for sensing HCMV by endosomal TLR-3/-9 in monocytic THP-1 cells
Keywords: HCMV; THP-1; SR-A1; TLR-2/-3/-9; TNF-α; IFN-β; IL-12p35
Differential relocation and stability of PML-body components during productive human cytomegalovirus infection: Detailed characterization by live-cell imaging
Keywords: HCMV; IE1-72K; ND10; PML; Sp100; hDaxx; STAT1; STAT2; Condensed chromatin; Live-cell microscopy
Identification of novel allosteric nonpeptidergic inhibitors of the human cytomegalovirus-encoded chemokine receptor US28
Keywords: HCMV; Viral GPCR; Nonpeptidergic; Constitutive activity; Chemokine; Inverse agonist; Herpesvirus
Enhanced SUMOylation of proteins containing a SUMO-interacting motif by SUMO-Ubc9 fusion
Keywords: SUMO; Ubc9; SUMO-interacting motif; SIM; IE2; Sp100; HCMV
Interaction of HCMV UL84 with C/EBPα transcription factor binding sites within oriLyt is essential for lytic DNA replication
Keywords: HCMV; DNA replication; OriLyt; Transcription factor binding site; C/EBPa
Recombinant human monoclonal antibodies to human cytomegalovirus glycoprotein B neutralize virus in a complement-dependent manner
Keywords: HCMV; Human antibody; Phage display; Antiviral agents
The tegument protein UL94 of human cytomegalovirus as a binding partner for tegument protein pp28 identified by intracellular imaging
Keywords: HCMV; Tegument protein; pp28; UL94; FRET; Intracellular image; Protein interaction
A model for HCMV infection in immunosuppressed patients
Keywords: HCMV; CMV; Herpes; Transplantation; Mathematical model; Immunosuppression
Hexamethylene bisacetamide can convert nonpermissive human cells to a permissive state for expressing the major immediate-early genes of human cytomegalovirus by up-regulating NF-κB activity
Keywords: HCMV; HMBA; HDAC inhibitors; MIE genes; MIEP; NF-κB; IκBα; Dominant negative IκBα; SN-50; PTD-p65-P1
Synthesis of 4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamides with broad-spectrum human herpesvirus polymerase inhibition
Keywords: Cytomegalovirus; HCMV; Varicella-zoster; VZV; HSV; EBV
Comparison of a new Light Diagnostics⢠and the CMV Brite⢠to an in-house developed human cytomegalovirus antigenemia assay
Keywords: HCMV; human cytomegalovirus; SOTR; solid-organ transplant recipients; HSCTR; hematopoietic stem cell transplant recipients; PBL; peripheral blood leukocytes; MAbs; monoclonal antibodies; IFA; indirect fluorescent antibody assay; Human cytomegalovirus; pp6
Identification of a highly conserved region in the human cytomegalovirus glycoprotein H gene and design of molecular diagnostic methods targeting the region
Keywords: HCMV; Glycoprotein H; Polymorphism; Diagnosis
HCMV microinfections in inflammatory diseases and cancer
Keywords: HCMV; Inflammatory disease; Cancer; Autoimmune diseases; TNF; Cardiovascular diseases
Molecular dissection of the human B cell response against cytomegalovirus infection by lambda display
Keywords: HCMV; Cytomegalovirus; Phage display; Antibody response; Antigen discovery
Inducibility of doxycycline-regulated gene in neural and neuroendocrine cells strongly depends on the appropriate choice of a tetracycline-responsive promoter
Keywords: DLR; dual-luciferase reporter assay; Dox; doxycycline; hCMV; human cytomegalovirus; PEF1α; human elongation factor 1α promoter; Phcmv IE1; human cytomegalovirus immediate early gene 1 promoter/enhancer; PhCMV*-1; original tetracycline-responsive promote
Refinement in the production and purification of recombinant HCMV IE1-pp65 protein for the generation of epitope-specific T cell immunity
Keywords: HCMV; IE1-pp65; Protein purification;
Human cytomegalovirus (HCMV) and hearing impairment: Infection of fibroblast cells with HCMV induces chromosome breaks at 1q23.3, between loci DFNA7 and DFNA49—Both involved in dominantly inherited, sensorineural, hearing impairment
Keywords: HCMV; Cytomegalovirus; Hearing impairment; DFNA7; DFNA49; MPZ; Chromosome break; Chromosome gap
Desensitization of herpesvirus-encoded G protein-coupled receptors
Keywords: GPCR; Cytomegalovirus; KSHV; HCMV; MCMV; US28; M33; ORF74; GRK; Arrestin; Desensitization
Nuclear trafficking of the human cytomegalovirus pp71 (ppUL82) tegument protein
Keywords: HCMV; Nuclear trafficking; Phosphorylation; Tegument; Mass spectrometry
Inhibition of IL-1β transcription by peptides derived from the hCMV IE2 transactivator
Keywords: hCMV; human cytomegalovirus; DBD; DNA-binding domain; IL1B; gene encoding IL-1β; TLR; Toll-like receptor; bZIP; basic leucine zipper domain; Interleukin 1β; Cytomegalovirus; IE2; Transcription factors; Peptide inhibitor;
Evidence for a detrimental role of nitric oxide synthesized by endothelial nitric oxide synthase after peripheral nerve injury
Keywords: eNOS; hypoglossal nerve; adenoviral vectors; peripheral neuropathy; Ad; adenovirus; AG; aminoguanidine; CMAP; compound muscle action potential; d-NAME; NÏ-nitro-d-arginine methyl ester; eGFP; enhanced green fluorescent protein; eNOS; endothelial isoform
MEN1 Missense Mutations Impair Sensitization to Apoptosis Induced by Wild-Type Menin in Endocrine Pancreatic Tumor Cells
Keywords: Ctrl; control; IB; immunoblotting; hCMV; human cytomegalovirus; IP; immunoprecipitation; MEN1; multiple endocrine neoplasia type 1; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; OD; optical density; PI; propidium iodide; VSVG; vesicul
High prevalence of an active human cytomegalovirus infection in patients with colonic diverticulitis
Keywords: HCMV, human cytomegalovirus; IBD, inflammatory bowel disease; IL-6, interleukin 6; IFN, interferon; TNF, tumor necrosis factorDiverticulitis; Perforated diverticulitis; HCMV
Synthesis and biological activation of an ethylene glycol-linked amino acid conjugate of cyclic cidofovir
Keywords: Prodrug; cHPMPC; HPMPC; Biotransformation; HCMV; Anti-viral; Biodefense
SAR studies on a novel series of human cytomegalovirus primase inhibitors
Keywords: Anti-viral; hCMV; Primase; Cytomegalovirus; Inhibitor
Proteasome-dependent, ubiquitin-independent degradation of Daxx by the viral pp71 protein in human cytomegalovirus-infected cells
Keywords: Daxx; HCMV; pp71; UL82; Ubiquitin-independent degradation; Proteasome
7-Oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides: Synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase
Keywords: Herpesvirus; Cytomegalovirus; HCMV; Herpes; VZV; HSV; Conformational restriction; Antiviral; Non-nucleoside;
2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases
Keywords: Cytomegalovirus; HCMV; Varicella-zoster; VZV; HSV
N-terminal determinants of human cytomegalovirus IE1 protein in nuclear targeting and disrupting PML-associated subnuclear structures
Keywords: HCMV; IE1; PML; Nucleus; Localization; SUMO
DNA vaccines expressing glycoprotein complex II antigens gM and gN elicited neutralizing antibodies against multiple human cytomegalovirus (HCMV) isolates
Keywords: HCMV; Vaccine; Glycoprotein; DNA immunization
Detection of oncogenic viruses (SV40, BKV, JCV, HCMV, HPV) and p53 codon 72 polymorphism in lung carcinoma
Keywords: HPV; Polyomaviruses; HCMV; p53 polymorphism; Lung cancer; Coinfections; PCR;
Variability of UL18, UL40, UL111a and US3 immunomodulatory genes among human cytomegalovirus clinical isolates from renal transplant recipients
Keywords: HCMV; Immunomodulatory genes; Variability; Transplantation
Targeting the NF-κB pathway through pharmacological inhibition of IKK2 prevents human cytomegalovirus replication and virus-induced inflammatory response in infected endothelial cells
Keywords: HCMV; Endothelial cells; Inflammatory response; Gene expression; NF-κB; IKK2
Bone-marrow-derived mesenchymal stem cells as a target for cytomegalovirus infection: Implications for hematopoiesis, self-renewal and differentiation potential
Keywords: HCMV; Virus-host interaction; Bone marrow; Mesenchymal stem cells; Hematopoietic stem cells; Hematopoiesis; Cell differentiation; Osteogenesis; Adipogenesis; Cell adhesion;
Ectopic expression of HCMV IE72 and IE86 proteins is sufficient to induce early gene expression but not production of infectious virus in undifferentiated promonocytic THP-1 cells
Keywords: Human cytomegalovirus; HCMV; Latency; Reactivation; THP-1; IE72; IE86; UL37x1
Prediction of endothelial cell tropism of human cytomegalovirus strains
Keywords: HCMV; human cytomegalovirus; EC; endothelial cells; MAbs; monoclonal antibodies; HUVEC; human umbilical vein endothelial cells; HELF; human embryonic lung fibroblasts;
Polymorphisms of human cytomegalovirus UL148A, UL148B, UL148C, UL148D genes in clinical strains
Keywords: HCMV; UL148A, UL148B, UL148C, UL148D ORF variability