Keywords: Breast cancer; HDAC1; Prognosis; Meta-analysis;
مقالات ISI (ترجمه نشده)
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Keywords: AI; aromatase inhibitor; AR; androgen receptor; CAF; cancer-associated fibroblast; CBR; clinical benefit rate; CDK; cyclin-dependent kinase; ctDNA; circulating tumor DNA; DNMT3B; DNA methyltransferase 3B; ER; estrogen receptor; ESR1; ER gene; HDAC1; histo
Keywords: â¢OH; hydroxyl radical; 2,2-BP; 2,2-bipyridyl; ABC; ATP-binding cassette; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; AMPKK; AMPK kinase; ANT; adenine nucleotide translocase; AP-1; activator protein 1; Apaf-1; protease activating
Keywords: 2210010C04Rik; RIKEN cDNA 2210010C04 gene; 5330417C22Rik; RIKEN cDNA 5330417C22 gene; A1AT; alpha1-antitrypsin; Ago1; argonaute RISC catalytic component 1; Amy2a5; amylase 2a5; Amy2b; amylase, alpha 2B; AP1/JUN; jun proto-oncogene; Bmp; bone morphogenetic
Stabilization of HDAC1 via TCL1-pAKT-CHFR axis is a key element for NANOG-mediated multi-resistance and stem-like phenotype in immune-edited tumor cells
Keywords: NANOG; HDAC1; CHFR; Immunotherapy; Chemoresistance; Immuneresistance;
p300 promotes differentiation of Th17 cells via positive regulation of the nuclear transcription factor RORγt in acute respiratory distress syndrome
Keywords: APACHE; Acute Physiology and Chronic Health Evaluation; ARDS; acute respiratory distress syndrome; BALF; bronchoalveolar lavage fluid; BNP; brain natriuretic peptide; DMSO; dimethyl sulfoxide; EDTA; ethylene diamine tetraacetic acid; HAT; histone acetyltr
The reciprocal link between EVI1 and miRNAs in human malignancies
Keywords: EVI1; ecotropic virus integration site-1; MiR; microRNA; 3â²-UTR; 3â²-untranslated regions; AML; acute myeloid leukemia; DNA; deoxyribonucleic acid; RNA; ribonucleic acid; NF-κβ; nuclear factor kappa β; CHIP; Chromatin Immunoprecipitation; c-Myb; c-m
The HDAC1/c-JUN complex is essential in the promotion of nerve injury-induced neuropathic pain through JNK signaling
Keywords: Neuropathic pain; Nerve injury; HDAC1; JNK; cJun;
Pterostilbene inhibits MTA1/HDAC1 complex leading to PTEN acetylation in hepatocellular carcinoma
Keywords: MTA1; Pterostilbene; HCC; HDAC1; PTEN; Ac-PTEN;
Polyphenolic derivatives from mango (Mangifera Indica L.) modulate fecal microbiome, short-chain fatty acids production and the HDAC1/AMPK/LC3 axis in rats with DSS-induced colitis
Keywords: AMPK; AMP-activated protein kinase; ATCC; American Type Culture Collection; Atgs; autophagy-related genes; DSS; dextran sodium sulfate; GAE; gallic acid equivalent; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GC-MS; gas chromatography-mass spectr
Nemo-like kinase (NLK) primes colorectal cancer progression by releasing the E2F1 complex from HDAC1
Keywords: NLK; E2F1; HDAC1; Cell cycle; Colorectal cancer;
Downregulation of PARP1 transcription by CDK4/6 inhibitors sensitizes human lung cancer cells to anticancer drug-induced death by impairing OGG1-dependent base excision repair
Keywords: CDK4/6; cyclin-dependent kinases 4 and 6; CDK2; cyclin-dependent kinase 2; iCDK4/6; inhibitor of CDK4/6; LEE011; inhibitor of CDK4/6, ribociclib, Kisqali; PD0332991; inhibitor of CDK4/6, palbociclib, Imbrance; NU6140; cyclin-dependent kinase 2 (CDK2) inhi
Synergistic activity of imatinib and AR-42 against chronic myeloid leukemia cells mainly through HDAC1 inhibition
Keywords: Chronic myeloid leukemia; Combination therapy; Imatinib; AR-42; HDAC1;
HDAC1 interacts with the p50 NF-κB subunit via its nuclear localization sequence to constrain inflammatory gene expression
Keywords: NF-κB; HDAC1; p50; Inflammation; Neutrophil;
Vaccarin protects human microvascular endothelial cells from apoptosis via attenuation of HDAC1 and oxidative stress
Keywords: Vaccarin; High glucose; Endothelial cells; Reactive oxygen species; HDAC1; Apoptosis;
The influence of peroxisome proliferator-activated receptor γ (PPARγ) ligands on cancer cell tumorigenicity
Keywords: Cancer cells; PPARγ agonist; PPARγ antagonist; Therapeutic agents; Tumorigenicity; ACC; Acetyl-CoA carboxylase; AKR1B10; Alde-keto reductase 1B10; Alpha-ESA; Alpha-eleostreac acid; ACLY; ATP citrate lyase; BADGE; Bisphenol-A-diglycidyl-etter; CSCs; Canc
Irradiation by γ-rays reduces the level of H3S10 phosphorylation and weakens the G2 phase-dependent interaction between H3S10 phosphorylation and γH2AX
Keywords: Mass spectrometry; Histones H3 and H4; γH2AX; DNA damage; Embryonic stem cells; Epigenetics; FLIM; Fluorescence lifetime image microscopy; FRET; Förster resonance energy transfer; H3; histone H3; H4; histone H4; me1; monomethylated histones; me2; dimeth
Histone deacetylase 1 promotes glioblastoma cell proliferation and invasion via activation of PI3K/AKT and MEK/ERK signaling pathways
Keywords: HDAC1; Glioblastoma; Proliferation; Invasion; Signaling pathway;
The NuRD complex-mediated p21 suppression facilitates chemoresistance in BRCA-proficient breast cancer
Keywords: CHD4; p21; HDAC1; BRCAness; DNA damage;
Modulations of DNMT1 and HDAC1 are involved in the OTA-induced cytotoxicity and apoptosis in vitro
Keywords: Ochratoxin A; DNMT1; HDAC1; Cytotoxicity; Apoptosis;
Andrographolide reduced VEGFA expression in hepatoma cancer cells by inactivating HIF-1α: The involvement of JNK and MTA1/HDCA
Keywords: Andrographolide; Hepatoma cancer; VEGFA; HIF-1α; MTA1; JNK; Andro; Andrographolide; VEGFA; Vascular endothelial growth factor A; HIF-1α; hypoxia-inducible factor 1-alpha; MTA1; metastasis-associated protein 1; HDAC1; histone deacetylase 1; JNK; c-Jun N-
Profiling of human epigenetic regulators using a semi-automated real-time qPCR platform validated by next generation sequencing
Keywords: MSC; Mesenchymal stromal/stem cell; AMSC; Adipose-tissue derived mesenchymal stromal/stem cell; RT-qPCR; Real-time reverse transcriptase quantitative polymerase chain reaction; RNA-seq; RNA sequencing; EpiReg; Epigenetic regulator; HAT; Histone acetyl tra
Activation of PPARγ inhibits HDAC1-mediated pulmonary arterial smooth muscle cell proliferation and its potential mechanisms
Keywords: Pulmonary arterial smooth muscle cell; HDAC1; PPARγ; miR-124; CDK4;
Nicotinamide nucleotide transhydrogenase (NNT) deficiency dysregulates mitochondrial retrograde signaling and impedes proliferation
Keywords: 3-BrPA; 3-bromopyruvate; ÎΨm; mitochondrial membrane potential; DMS; dimethyl succinate; HDAC; histone deacetylase; ETC; electron transport chain; HIF-1; hypoxia-inducible factor 1; IGF-1R; insulin-like growth factor 1 receptor; IDH; isocitrate dehydrog
Coexpression of SALL4 with HDAC1 and/or HDAC2 is associated with underexpression of PTEN and poor prognosis in patients with hepatocellular carcinoma
Keywords: SALL4; HDAC1; HDAC2; PTEN; Hepatocellular carcinoma;
Cobalt chloride-mediated protein kinase Cα (PKCα) phosphorylation induces hypoxia-inducible factor 1α (HIF1α) in the nucleus of gastric cancer cell
Keywords: Cobalt chloride; Gastric epithelial cell; HIF1α; Hypoxia; p300; PKC; CoCl2·6H2O; Cobalt chloride hexahydrate; DAG; Diacylglycerol; DAPI; 4â²,6-Diamidino-2-Phenylindole, Dilactate; DN; Dominant negative; GECs; Gastric epithelial cells; HDAC1; Histone-de
Loss of histone deacetylase HDAC1 induces cell death in Drosophila epithelial cells through JNK and Hippo signaling
Keywords: HDAC1; Rpd3; NuRD; Sin3; JNK; Hippo; Yki; Drosophila; Epithelial; Apoptosis
Hepatitis B virus basal core promoter mutations show lower replication fitness associated with cccDNA acetylation status
Keywords: BCP; basal core promoter; CHB; chronic HBV; cccDNA; covalently closed circular DNA; DNMT; DNA methyltransferases; DS DNA; double stranded DNA; HATs; histone acetyltransferases; HDAC1; class 1 histone deacetylase; OC DNA; open circular DNA; ORFs; open read
KLF17 attenuates estrogen receptor α-mediated signaling by impeding ERα function on chromatin and determines response to endocrine therapy
Keywords: Estrogen receptor α; KLF17; Breast cancer; Endocrine therapy; HDAC1; p300;
TDP-43/FUS in motor neuron disease: Complexity and challenges
Keywords: AD; Alzheimer's disease; Ago2; Argonaute 2; ALS; Amyotrophic lateral sclerosis; ALS/PD; amyotrophic lateral sclerosis and Parkinsonism-dementia complex; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ATF3; activating transcription factor 3
Scopoletin has a potential activity for anti-aging via autophagy in human lung fibroblasts
Keywords: Scopoletin; p53; HDAC1; Autophagy; Aging; IMR 90
Loss of histone deacetylase Hdac1 disrupts metabolic processes in intestinal epithelial cells
Keywords: Hdac1; Mitochondria; Reactive oxygen species; AMPK; Intestinal epithelial cell; Acetylation;
HDAC1 overexpression independently predicts biochemical recurrence and is associated with rapid tumor cell proliferation and genomic instability in prostate cancer
Keywords: Prostate cancer; ERG; HDAC1; Genomic deletions; Prognosis; Immunohistochemistry; Tissue microarray;
Non-coding RNAs in gastric cancer
Keywords: ncRNAs; non-coding RNAs; sncRNAs; small ncRNAs; lncRNAs; long ncRNAs; snoRNAs; small nucleolar RNAs; piRNAs; Piwi-associated RNAs; miRNAs; microRNAs; tiRNAs; transcription initiation RNAs; lincRNAs; long intergenic ncRNAs; GC; gastric cancer; nts; nucleot
Research ArticleHBx relieves chromatin-mediated transcriptional repression of hepatitis B viral cccDNA involving SETDB1 histone methyltransferase
Keywords: HBV; Hepatitis B Virus; pgRNA; pre-genomic RNA; RC-DNA; relaxed-circular HBV DNA; cccDNA; covalently closed circular HBV DNA; CBP; CREB-binding protein; PCAF; p300/CREB-binding Protein-associated Factor; H3, H4; histone 3, histone 4; HDAC1; histone deacet
Research reportReduced serine racemase expression in aging rat cerebellum is associated with oxidative DNA stress and hypermethylation in the promoter
Keywords: SR; serine racemase; DAAOx; D-amino acid oxidase; DNMT; DNA methyltransferase; HDAC1; histone deacetylase 1; 5-mC; 5-methylcytosine; 5-hmC; 5-hydroxymethylcytosine; PCR; polymerase chain reaction; qRT-PCR; quantitative real-time PCR; BSP; bisulfite sequen
Histone deacetylase1 promotes TGF-β1-mediated early chondrogenesis through down-regulating canonical Wnt signaling
Keywords: Chondrogenesis; TGF-β1; HDAC1; Wnt/β-catenin; Deacetylation;
Chromatin remodeling protein SMAR1 regulates NF-κB dependent Interleukin-8 transcription in breast cancer
Keywords: SMAR1; NF-κB; HDAC1; Transcription; Repressor;
Insulin drives glucose-dependent insulinotropic peptide expression via glucose-dependent regulation of FoxO1 and LEF1/β-catenin
Keywords: Akt; Serine/threonine-specific protein kinase also known as Protein Kinase B (PKB); ChIP; Chromatin immunoprecipitation; FoxO1; Forkhead box protein O1; GLP-1; Glucagon-Like Peptide 1; HDAC1; Histone Deacetylase 1; IRE; Insulin-Response Element; PI3K; Pho
TIP30 nuclear translocation negatively regulates EGF-dependent cyclin D1 transcription in human lung adenocarcinoma
Keywords: TIP30; EGFR; Cyclin D1; HDAC1; Lung adenocarcinoma;
Berberine and S allyl cysteine mediated amelioration of DENÂ +Â CCl4 induced hepatocarcinoma
Keywords: ROS; reactive oxygen species; FACS; fluorescence activated cell sorter; DCFDA; 2â²,7â²-Dichlorofluorescein diacetate, TCA, tri choloro-acetic acid; HDAC1; histone deacetylase type1; pMdm2; phosphorylated Mdm2; PP2A; protein phosphatease 2A; MMP; mitocho
Effect of vitrification on promoter CpGÂ island methylation patterns and expression levels of DNA methyltransferase 1o, histone acetyltransferase 1, and deacetylase 1 in metaphase II mouse oocytes
Keywords: CpG island methylation; Dnmt1o; Hat1; Hdac1; vitrification;
High expression of SNIP1 correlates with poor prognosis in Non-small cell lung cancer and SNIP1 interferes with the recruitment of HDAC1 to RB in vitro
Keywords: SNIP1; RB; HDAC1; Prognosis; Lung cancer;
The DEAD box proteins DDX5 (p68) and DDX17 (p72): Multi-tasking transcriptional regulators
Keywords: ERα; estrogen receptor alpha; CBP; CREB-binding protein; SRC-1; steroid receptor coactivator 1; SRA; steroid receptor RNA activator; RNA Pol II; RNA polymerase II; P/CAF; CBP/p300 associated factor; TFIIA; transcription factor IIA; AR; androgen receptor;
Nemo-like kinase, a multifaceted cell signaling regulator
Keywords: NLK; Nemo-like kinase; IL-6; intereukin-6; MAPK; mitogen activated protein kinase; ERK; extracellular-signal regulated kinase; Pro; proline; Ser; serine; Thr; threonine; C. elegans; Caenorhabditis elegans; POP-1; Posterior pharynx defect protein 1; LEF1;
Depletion of Suds3 reveals an essential role in early lineage specification
Keywords: Suds3; Sin3a; Hdac1; ICM; Trophectoderm; Primitive endoderm; Lineage specification;
Combining microRNA-449a/b with a HDAC inhibitor has a synergistic effect on growth arrest in lung cancer
Keywords: HDAC1; MicroRNA; Non-small cell lung cancer
Increased inflammation and brain injury after transient focal cerebral ischemia in activating transcription factor 3 knockout mice
Keywords: AP-1; activator protein 1; ATF3; Activating transcription factor; CBF; cerebral blood flow; CREB; cAMP-responsive element-binding protein; HDAC1; histone deacetylase 1; ICAM; intercellular adhesion molecule; IL; interleukin; KO; knockout; MCA; middle cere
p300/CBP acetyl transferases interact with and acetylate the nucleotide excision repair factor XPG
Keywords: APE1; AP-endonuclease 1; BER; base excision repair; CBP; CREB-binding protein; CPD; cyclobutane pyrimidine dimers; FEN1; flap endonuclease 1; HAT; histone acetyltransferase; HDAC1; histone deacetylase 1; KAT; lysine acetyltransferase; MPG; methylpurine DN
Towards the elucidation of the regulatory network guiding the insulin producing cells' differentiation
Keywords: NGN3 (NEUROG3); neurogenin3; ESCs; Embryonic Stem Cells; TFBS; Transcription Factor Binding Sites; TFs; Transcription Factors; AP4 (TFAP4); Activating enhancer-binding Protein 4 (Transcription Factor AP-4); WISP1; WNT-Induced Secreted Protein 1; CTGF; Con