Keywords: COPD; chronic obstructive pulmonary disease; O3; ozone; BUD; budesonide; BALF; bronchoalveolar lavage fluid; MMP; matrix metalloproteinase; HIF-1α; hypoxia-inducible factor-1α; VEGF; vascular endothelial growth factor; α-SMA; α-smooth muscle actin; GS
مقالات ISI (ترجمه نشده)
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Keywords: Alzheimer's disease; BDNF; Epigenetic; HDAC2; Hippocampus;
Keywords: AP-1; activator protein 1; BALF; bronchoalveolar lavage fluid; BCL; B-cell lymphoma; CFTR; cystic fibrosis transmembrane conductance regulator; CXCL; chemokine CXC motif ligand; EGR-1; early growth protein 1; FOXO1; forkhead box protein O1; HDAC2; histone
Keywords: CSE; Cigarette smoke extracts; FP; Fluticasone propionate; FO; Formoterol fumarate dehydrate; GR; Glucocorticoid receptor; NF-κB; Nuclear factor-κB; ERK; Extracellular signal-regulated kinase1/2; HDAC2; Histone deacetylase 2; HDAC3; Histone deacetylase
Keywords: Childhood asthma; asthma phenotypes; gene expression profiling; microarray analysis; longitudinal study; ADD3; Adducin 3 (gamma); CAMP; Childhood Asthma Management Program; DE; Differentially expressed; FDR; False discovery rate; GR; Glucocorticoid recept
Keywords: 11β-HSD2; 11β-hydroxysteroid dehydrogenase type 2; ACTH; adrenocorticotropic hormone; AP-1; activator protein-1; GC; glucocorticoid; GR; glucocorticoid receptor; HDAC2; histone deacetylase 2; hGR; human glucocorticoid receptor; HPA; hypothalamuspituitar
Keywords: ACT; asthma control test; α-1 AT; α-1 antitrypsin; ALQ; asthma life quality; BMI; body mass index; CARAT; control asthma and allergic rhinitis test; COPD; chronic obstructive pulmonary disease; GERD; gastroesophageal reflux disease; HDAC2; histone deace
Keywords: Prenatal glucocorticoids; ADMA; DNA oxidative damage; TNF-α; HDAC2; Lung dysplasia;
Keywords: schizophrenia; mGlu2R; 5-HT2A; PAMs; HDAC2; epigenetics;
Keywords: Artesunate; Airway inflammation; PI3Kδ; HDAC2; Glucocorticoid; Severe asthma;
Keywords: Corticosteroids; bronchodilator; cytokine; chemokine; IgE; kinase; p38 mitogen-activated protein kinase; bronchial thermoplasty; corticosteroid resistance; macrolide; ACOS; Asthma-chronic obstructive pulmonary disease overlap syndrome; COPD; Chronic obs
Keywords: Amygdala; Anxiety; Adolescent binge drinking; Alcohol intake; Epigenetic; HDAC2; Histone acetylation;
Keywords: Fear extinction; Exposure therapy; Augmented relearning; Reconsolidation; Drug development; Cognitive enhancer; 5-HT; 5-hydroxytryptamine = serotonin; AC; adenylate cyclase; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AMY; amygdala; BA;
Keywords: Addiction; AMPAR; CoREST; HDAC2; MeCP2; NMDAR; REST; valproic acid;
Keywords: ABC; ATP binding cassette; ADR; adverse drug reactions; ALA; alpha-linolenic acid; ALT; alanine aminotransferase; CVD; cardiovascular disease; AUC; area under the concentration-time curve; Cmax; maximal plasma concentration; CYP; cytochrome P; EGCG; epi
HDAC2 Suppresses IL17A-Mediated Airway Remodeling in Human and Experimental Modeling of COPD
Keywords: airway inflammation; airway remodeling; COPD; HDAC2; IL-17A; CS; cigarette smoke; CSE; cigarette smoke extract; CXCL; chemokine (C-X-C motif) ligand; ECM; extracellular matrix; HBE; human bronchial epithelial; HDAC; histone deacetylase; HRCT; high-resolut
HDAC2-dependent Antipsychotic-like Effects of Chronic Treatment with the HDAC Inhibitor SAHA in Mice
Keywords: histone deacetylase (HDAC); HDAC2; vorinostat (SAHA); antipsychotics; clozapine; schizophrenia;
MiR-455-3p activates Nrf2/ARE signaling via HDAC2 and protects osteoblasts from oxidative stress
Keywords: Osteoporosis; Osteoblasts; MiR-455-3p; HDAC2; Oxidative stress;
Role of statins and mevalonate pathway on impaired HDAC2 activity induced by oxidative stress in human airway epithelial cells
Keywords: Dexamethasone (PubChem CID: 5743), simvastatin (PubChem CID: 54454); Y27632 (PubChem CID: 448042); Oxidative stress; HDAC2; A549 cells; Mevalonate; Statins;
Loss of histone deacetylase 2 inhibits oxidative stress induced by high glucose via the HO-1/SIRT1 pathway in endothelial progenitor cells
Keywords: DFU; diabetic foot ulcer; EPC; endothelial progenitor cells; HDAC2; histone deacetylase 2; ROS; reactive oxygen species; HO-1; home oxygenase; VEGF; vascular endothelial growth factor; IGF-1; insulin-like growth factor-1; FBS; fetal bovine serum; Diabetic
Profiling of human epigenetic regulators using a semi-automated real-time qPCR platform validated by next generation sequencing
Keywords: MSC; Mesenchymal stromal/stem cell; AMSC; Adipose-tissue derived mesenchymal stromal/stem cell; RT-qPCR; Real-time reverse transcriptase quantitative polymerase chain reaction; RNA-seq; RNA sequencing; EpiReg; Epigenetic regulator; HAT; Histone acetyl tra
Research paperHigh-expressing cystic fibrosis transmembrane conductance regulator interacts with histone deacetylase 2 to promote the development of Ph+ leukemia through the HDAC2-mediated PTEN pathway
Keywords: CFTR; cystic fibrosis transmembrane conductance regulator; HDAC2; histone deacetylase 2; MS; mass spectrometry; ChIP; chromatin immunoprecipitation; LC-MS; liquid chromatography-mass spectrometry; Cystic fibrosis transmembrane conductance regulator (CFT
Cardiac reprogramming factor Gata4 reduces postinfarct cardiac fibrosis through direct repression of the profibrotic mediator snail
Keywords: cardiac reprogramming; Gata4; fibrosis; Snail; αSMA; α-smooth muscle actin; ANOVA; analysis of variance; bp; base pair; ChIP; chromatin immunoprecipitation; EF; ejection fraction; EMT; epithelial-mesenchymal transition; GFP; green fluorescent protein; G
Coexpression of SALL4 with HDAC1 and/or HDAC2 is associated with underexpression of PTEN and poor prognosis in patients with hepatocellular carcinoma
Keywords: SALL4; HDAC1; HDAC2; PTEN; Hepatocellular carcinoma;
Melittin ameliorates CVB3-induced myocarditis via activation of the HDAC2-mediated GSK-3β/Nrf2/ARE signaling pathway
Keywords: Melittin; CVB3; Myocarditis; HDAC2; GSK-3β/Nrf2/ARE signaling pathway;
HDAC2 promotes the migration and invasion of non-small cell lung cancer cells via upregulation of fibronectin
Keywords: HDAC2; NSCLC; Migration; Fibronectin; p65;
Repeated lipopolysaccharide exposure causes corticosteroid insensitive airway inflammation via activation of phosphoinositide-3-kinase δ pathway
Keywords: Airway inflammation; Corticosteroid-resistance; COPD; HDAC2; PI3K Nrf2
Role of histone deacetylases(HDACs) in progression and reversal of liver fibrosis
Keywords: Liver fibrosis; HDACs; Reversal of liver fibrosis; HDAC2;
Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD
Keywords: COPD; host defense; infection; viral disease; 3-NT; 3-nitrotyrosine; 8-OHdG; 8-hydroxy-2'-deoxyguanosine; GM-CSF; granulocyte-macrophage colony-stimulating factor; GOLD; Global Initiative for Obstructive Lung Disease; HDAC2; histone deacetylase-2; MMP-9;
HDAC2 expression in parvalbumin interneurons regulates synaptic plasticity in the mouse visual cortex
Keywords: HDAC2; Parvalbumin; Visual cortex; Plasticity; Interneuron; LTD
Carbocysteine restores steroid sensitivity by targeting histone deacetylase 2 in a thiol/GSH-dependent manner
Keywords: Steroid sensitivity; HDAC2; Thiol/GSH; S-CMC; Combination therapy;
miR-200c-SUMOylated KLF4 feedback loop acts as a switch in transcriptional programs that control VSMC proliferation
Keywords: ATRA; all-trans retinoic acid; cdk2; cyclin-dependent kinase 2; HASMC; human aortic smooth muscle cell; HDAC2; histone deacetylase 2; KLF; Krüppel-like factor; LSD1; lysine-specific demethylase 1; miR; microRNA; NCoR; nuclear receptor corepressor; p21; p
Epigenomics of Alzheimer's disease
Keywords: AD; Alzheimer's disease; APOE; apolipoprotein E; APP; amyloid precursor protein; BACE-1; beta-site APP-cleaving enzyme 1 gene; CG; cytosine-guanine dinucleotide; ChIP-Seq; chromatin immunoprecipitation-sequencing; CVD; cerebrovascular disease; GWAS; gen
Comprehensive DNA methylation analysis of human neuroblastoma cells treated with blonanserin
Keywords: DRD2; dopamine receptor 2; GWAS; genome-wide association study; HDAC2; histone deacetylase 2; HTR2A; serotonin receptor 2A; mGluR2; metabotropic glutamate receptor 2; PCA; principle component analysis; Blonanserin; DNA methylation; Human neuroblastoma cel
A chromatin modifier regulates Sertoli cell response to mono-(2-ethylhexyl) phthalate (MEHP) via tissue inhibitor of metalloproteinase 2 (TIMP2) signaling
Keywords: SCs; Sertoli cells; DEHP; di(2-ethylhexyl)phthalate; MEHP; mono-(2-ethylhexyl) phthalate; Timp2/TIMP2; tissue inhibitor of metalloproteinase 2; Mta1/MTA1; metastasis associated protein 1; MMP2; matrix metalloproteinase 2; NuRD; nucleosome remodeling and h
Histone deacetylase 2 controls p53 and is a critical factor in tumorigenesis
Keywords: Cancer; HDAC inhibitors; HDAC2; p53; RLIM; Sumoylation;
MiR-145 functions as a tumor suppressor by directly targeting histone deacetylase 2 in liver cancer
Keywords: MiR-145; HDAC2; Tumor suppressor; Liver cancer;
ELAV proteins along evolution: Back to the nucleus?
Keywords: RBP; RNA-binding protein; elav; embryonic lethal abnormal vision; miRNA; microRNA; rbp9; RNA-binding protein 9; fne; found in neurons; ARE; AU-rich element; UTR; untranslated region; RRM; RNA recognition motif; PABP; polyA-binding protein; eiF4A; eukaryot
Aberrant Histone Deacetylase2–Mediated Histone Modifications and Synaptic Plasticity in the Amygdala Predisposes to Anxiety and Alcoholism
Keywords: Amygdala; anxiety and alcoholism; BDNF; dendritic spines; epigenetic; HDAC2
Baicalin is anti-inflammatory in cigarette smoke-induced inflammatory models in vivo and in vitro: A possible role for HDAC2 activity
Keywords: Baicalin; Cigarette smoke; Inflammation; COPD; HDAC2;
Phosphoinositide 3-kinase delta (PI3Kδ) in leukocyte signaling and function
Keywords: PI3Kδ; phosphoinositide 3-kinase delta; PIP3; phosphoinositide 3,4,5-triphosphates; SH2; Src homology-2; PH; pleckstrin homology; KD; kinase-dead; KO; knockout; BCR; B cell receptor; GPCR; G protein-coupled receptor; TCR; T cell receptor; FcεRI; high af
Protein kinase CK2-mediated phosphorylation of HDAC2 regulates co-repressor formation, deacetylase activity and acetylation of HDAC2 by cigarette smoke and aldehydes
Keywords: HDAC2; COPD; Phosphorylation; Inflammation; Oxidants; Lung
Cell-specific epigenetic regulation of ChM-I gene expression: Crosstalk between DNA methylation and histone acetylation
Keywords: Chondromodulin-I; Histone modification; Acetylation; Differentiation; Epigenetic; Chondrogenic; Methylation; H3-K9; HDAC2
Trichostatin A improves insulin stimulated glucose utilization and insulin signaling transduction through the repression of HDAC2
Keywords: Trichostatin A; HDAC2; Glucose utilization; Insulin sensitivity