Keywords: CVDs; cardiovascular diseases; ECs; endothelial cells; VSMCs; vascular smooth muscle cells; HPTMs; histones post-translational modifications; nt; nucleotides; 5-mC; 5-methylcytosine; 5-hmC; 5-hydroxymethylcytosine; CpG; sequence of cytosine followed by a
مقالات ISI (ترجمه نشده)
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Keywords: Peroxisome; Cancer; Pexophagy; Plasmalogen; Mitochondrion; Metabolism; AA; arachidonic acid; ABCD; ATP-binding cassette (ABC) transporters subfamily D; ACOX; Acyl Coenzyme-A oxidase; AGPS; alkyl-glycerone phosphate synthase; AMACR; α-Methylacyl-CoA racem
Keywords: FK228 (PubChem CID: 5352062); PXD101 (PubChem CID: 6918638); SAHA (PubChem CID: 5311); LBH-589 (PubChem CID: 6918837); tubacin (PubChem CID: 6675804); tubastatin A (PubChem CID: 49850262); ACY-1215 (PubChem CID: 53340666); ACY-241 (PubChem CID: 53340426);
Keywords: ARV-825 PubChem CID 92044400; BETd-246 PubChem CID 131698640; dBET1 PubChem CID 91799313; I-BET151 PubChem CID 52912189; I-BET762 PubChem CID 46943432; JQ1 PubChem CID 46907787; MS417 PubChem CID 59190723; OTX015 PubChem CID 9936746; THZ1 PubChem CID 7360
Keywords: HDACi; histone deacetylase inhibitor; HDAC; histone deacetylase; SCFA; short-chain fatty acids; GSTs; glutathione-S transferases; NRP-1; Neuropilin-1; P-gp; P-glycoprotein; CI; combination index; Butyrate; Colorectal cancer; Dietary fiber; Synergistic eff
Keywords: 5mC; 5- hydroxymethylcytosine; AML; acute myeloid leukemia; BET; bromodomain inhibitors; CCOC; clear cell ovarian cancer; ctDNA; cell-free tumor DNA; ChIP-on-chip; chromatin immunoprecipitation with DNA microarray; CIMP; CpG island methylator phenotype; C
Keywords: Arsenic; Cell Malignant Transformation; Histone Acetylation and Methylation; LC-MS/MS Based Histone Modification Analysis; ac; Acetyl/Acetylated; AGC; Automatic Gain Control; BCa; Bladder Cancer; CID; Collision-Induced Dissociation; DTT; Dithiothreitol; I
Keywords: ac; acetylation; BET; bromodomain and extra terminal family proteins; BMP7; bone morphogenic protein 7; BRD4; bromodomain-containing protein 4; bp; base pairs; CKD; chronic kidney disease; CTGF; connective tissue growth factor; DDR; DNA damage response; D
Keywords: Apigenin; HATs; HDACs; HDACi; Prostate cancer; Flavonoid;
Keywords: TME; tumour microenvironment; PD-1; programmed cell death 1; PD-L1; programmed death ligand 1; PD-L2; programmed death ligand 2; PTMs; post-translational histone modifications; DNMTi; DNA methyltransferase inhibitor; HDACi; histone deacetylase inhibitor;
Keywords: BAL; bronchoalveolar lavage; ChIA-PET; chromatin interaction analysis with paired-end tag; ChIP-seq; chromatin inmunoprecipitation and massively parallel sequencing; circ-ncRNA; circulating noncoding RNA; CRC; colorectal cancer; CRISPR-Cas9; clustered, re
Keywords: HDAC; histone deacetylase; HDACi; histone deacetylase inhibitors; COX; cyclooxygenases; NSAIDs; non-steroidal anti-inflammatory drugs; AR; androgen receptor; ZBG; zinc binding group; PGE2; prostaglandin E2;
Design, synthesis and evaluation of antiproliferative activity of melanoma-targeted histone deacetylase inhibitors
Keywords: HDAC; histone deacetylase; HDACi; histone deacetylase inhibitors; ZBG; zinc binding group;
Keywords: DAC; 5-Aza-2â²-deoxycytydine; DNMT; DNA methyltransferase; HAT; histone acetyltransferase; HDAC; histone deacetylase; HDACì; HDAC inhibitors; IL-2; interleukin-2; INS; insulin; LADA; latent autoimmune diabetes in adults; miRNA; microRNA; PBMCs; peripher
Anticancer properties of sodium selenite in human glioblastoma cell cluster spheroids
Keywords: 3D culture; Three dimension cell culture; ABC; ATP-binding cassette; ANOVA; analysis of variance; AOBS; Acousto-Optical Beam Splitter; APMA; amino-phenyl mercuric acetate; BBB; blood brain barrier; BSA; bovine serum albumin; CA9; carbonic anhydrase 9; DME
Keywords: GD; Gaucher disease; LSDs; lysosomal storage disorders; GLD; globoid cell leukodystrophy; IDS; iduronate-2-sulfatase; MPS IVA; Mucopolysaccharidosis type IVA; NPC; Niemann-Pick disease type C; GALNS; N-acetylgalactosamine-6-sulfate sulfatase; AGU; Asparty
Keywords: HDACi; histone deacetylase inhibitor; GPR; G-protein coupled receptor; BMMC; bone marrow derived mast cells; SCFA; short chain fatty acid; Ac-H3K9; acetylated histone 3 lysine 9; TSA; trichostatin A; BSA; bovine serum albumin; PARP; poly (ADP-ribose) poly
Keywords: BDNF; brain derived neurotropic factor; CCI; chronic constriction injury; CFA; complete Freund's adjuvant; CNS; central nervous system; GAD; glutamic acid decarboxylase; GLT-1; glutamate transporter-1; HDACs; histone deacetylases; HDACI; histone deacety
Keywords: HDAC6 selective inhibitor; Computer-aided drug design; Anti-sepsis; HDAC; histone deacetylase; LPS; lipopolysaccharide; HDACi; histone deacetylase inhibitors; IL; interleukin; IFNγ; interferon γ; TNF-α; tumor necrosis factor-α; ZBD; zinc-binding group
Keywords: Breast cancer; SERMs; HDACi; Ferrocenyl
Keywords: Ca2+ channel; K+ channel; Ca2+-activated Clâ channel; Transcription; Pre-mRNA splicing; Protein degradation; AD; Alzheimer's disease; ADPR; ADP ribose; AITC; allyl isothiocyanate; AKAP; A-kinase anchoring protein; AMPK; 5â² AMP-activated protein kinase
Keywords: ACSF; artificial cerebrospinal fluid; BDNF; brain-derived neurotrophic factor; CLP; cecal ligation and perforation; DTT; dithiothreitol; HAT; histone acetyltransferase; HDAC; histone deacetylase; HDACi; histone deacetylase inhibitors; NGF; nerve growth fa
Keywords: HD; Huntington's disease; htt gene; huntingtin gene; HDACi; histone deacetylase inhibitors; RNAi; RNA interference; ASO; antisense oligonucleotide; Tgasei; transglutaminase inhibitors; Huntington's disease (HD); htt gene; Histone deacetylase inhibitors (H
Keywords: Polymeric nanoparticle; Epigenetic inhibitor; Drug delivery; Controlled release; Stimuli-responsive; ADCA; adenocarcinoma; BrD; bromodomain; BRET; bioluminescence resonance energy transfer; DDS; drug delivery system; DLS; dynamic light scattering; DMF; di
Keywords: Estrogen receptor; Antiestrogens; HDACi; Breast cancer;
Keywords: Epigenetics; Stroke; Innate and adaptive response; HDACi; Antagomir
Keywords: ADX; adrenalectomized; ASD; autism spectrum disorders; BD; bipolar disorder; CSF; cerebrospinal fluid; DAMPs; damage-associated molecular patterns; FS; forced swimming; HDACi; histone deacetylase inhibitor; HSP; heat shock protein; IDO; indoleamine 2,3 di
Keywords: acH3; acetylated histone 3; acH4; acetylated histone 4; CCI; chronic constriction injury; CGI; CpG island; DNMT; DNA methyltransferase; DRG; dorsal root ganglion; HAT; histone acetyltransferase; HATi; HAT inhibitor; HDAC; histone deacetylase; HDACi; HDAC
Keywords: Histone deacetylases; Histone deacetylases inhibitors; Heart failure; Hypertrophy; DOCA; deoxycorticosterone acetate; HAT; histone acetyltransferases; HDAC; histone deacetylase; HDACi; histone deacetylase inhibitor; MEF2; myocyte enhancer factor-2; MITR;
Keywords: α-KG; alpha-ketoglutarate; 2-HG; 2-hydroxyglutarate; 5hmC; 5-hydroxymethylcytosine; 5mC; 5-methylcytosine; AML; acute myeloid leukemia; ASXL1; additional sex combs-like 1; AZA; azacytidine; CMML; chronic myelomonocytic leukemia; DAC; decitabine; DNMT3A;
Keywords: HDACi; Histone Deacetylase Inhibitor; Largazole; Class I Histone Deacetylase Inhibitor; Pyridine analogs; Cytotoxic and biochemical assays;
Keywords: DC; dyskeratosis congenita; DOXO; doxorubicin; HDACi; histone deacetylase inhibitor; TSA; trichostatin A; CQ; chloroquine; SAH; senescence-associated heterochromatinization; Senescence-associated heterochromatinization; Dyskeratosis congenita; DNA damage;
Keywords: histone acetylation; HDACi; learning and memory; epigenetics; transcriptional regulation; activity-driven transcription; histone code
Keywords: 8-iso-PGF2α; 8-iso-prostaglandin F2α; BBB; blood-brain barrier; COX; cyclooxygenase; ERK1/2; extracellular signal-regulated kinase; GAPDH; glyceraldehyde-3-phosphate-dehydrogenase; HAT; histone acetyl transferase; HDAC; histone deacetylase; HDACi; HDA
Keywords: Cholesterol; Oxysterol; CYP46A1; CYP27A1; CYP3A4; CYP39A1; CYP7B1; CH25H; Cholesterol 7α-hydroxylase; Sterol 27-hydroxylase; Cholesterol 24-hydroxylase; Cholesterol 25-hydroxylase; Oxysterol 7α-hydroxylase; 24-hydroxycholesterol 7α-hydroxylase; Epigene
Keywords: BDNF; brain derived neurotrophic factor; CAMKII; calmodulin-dependent protein kinase II; Ca2+; calcium; cAMP; cyclic adenosine monophosphate; CBS; cystathionine-β-synthase; CCI; chronic constriction injury; CFA; complete Freund's adjuvant; cGMP; cyclic
HDACis (class I), cancer stem cell, and phytochemicals: Cancer therapy and prevention implications
Keywords: Cancer; HDAC; HDACi; CSCs; Phytochemical; HDAC class I; Herbal medicine;
Tat controls transcriptional persistence of unintegrated HIV genome in primary human macrophages
Keywords: HIV; Unintegrated HIV DNA; Macrophage; Transcription; Tat; Persistence; Reservoir; HDACi;
Suppression of HDAC2 in Spinal Cord Alleviates Mechanical Hyperalgesia and Restores KCC2 Expression in a Rat Model of Bone Cancer Pain
Keywords: BCP; bone cancer pain; DMSO; dimethyl sulfoxide; DRG; dorsal root ganglion; HDAC; histone deacetylase; HDACi; histone deacetylase inhibitors; IOD; integrals of optical density; KCC2; potassium-chloride cotransporter 2; MOR; μ-opioid receptor; PBS; phosph
HDAC11 is a regulator of diverse immune functions
Keywords: APC; antigen presenting cell; CTCL; cutaneous T-cell lymphoma; DAMP; Damage associated molecular pattern; DC; dendritic cell; FDA; U.S. Food and Drug Administration; GVHD; graft versus host disease; HAT; histone acetyltransferase; HDAC; histone deacetylas
HDAC inhibitors as epigenetic regulators for cancer immunotherapy
Keywords: AICD; activation-induced cell death; AML; acute myeloid leukemia; APC; antigen-presenting cells; CAR; coxsackie- and adenovirus receptor; CDKs; cyclin-dependent kinases; CG; cancer germline; DCs; dendritic cells; HAT; histone acetyltransferase; HDAC; hist
Latent consequences of early-life lead (Pb) exposure and the future: Addressing the Pb crisis
Keywords: CDC; Centers for Disease Control (USA); DNA; deoxyribonucleic acid; EPA; Environmental Protection Agency (USA); GCF; Great Chinese Famine; HDACi; histone deacetylase inhibitors; miRNA; microRNA; Pb; lead; ppb; parts per billion; RNA; ribonucleic acid; tLE
Design and biological evaluation of tetrahydro-β-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors
Keywords: Histone deacetylase; HDAC; Histone deacetylase inhibitor; HDACi; Tetrahydro-β-carboline; Histone deacetylase 6 inhibition assay;
The influence of peroxisome proliferator-activated receptor γ (PPARγ) ligands on cancer cell tumorigenicity
Keywords: Cancer cells; PPARγ agonist; PPARγ antagonist; Therapeutic agents; Tumorigenicity; ACC; Acetyl-CoA carboxylase; AKR1B10; Alde-keto reductase 1B10; Alpha-ESA; Alpha-eleostreac acid; ACLY; ATP citrate lyase; BADGE; Bisphenol-A-diglycidyl-etter; CSCs; Canc
SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling
Keywords: SAHA; Suberoylanilide hydroxamic acid; AMPK; AMP-dependent protein kinase; HDAC; histone deacetylase; HDACi; Histone deacetylase inhibitor; mTOR; Mechanistic target of rapamycin; NHEJ; Non-homologous end joining; TSA; Trichostatin A; H3K36; Histone H3 lys
Controlled release of an HDAC inhibitor for reduction of inflammation in dry eye disease
Keywords: HDACi; SAHA; Microspheres; PLGA; Dry eye disease;
Biotechnology Challenges to In Vitro Maturation of Hepatic Stem Cells
Keywords: Liver Development; Differentiation; Hepatocyte; Culture; CRISPR; clustered regularly interspaced short palindromic repeats; CYP; cytochrome P450; 3D; 3-dimensional; DNMTi; DNA methylation inhibitor; ECM; extracellular matrix; ESC; embryonic stem cell; ES-
Co-targeting of BET proteins and HDACs as a novel approach to trigger apoptosis in rhabdomyosarcoma cells
Keywords: Apoptosis; Cell death; Mitochondria; HDAC; BET proteins; Rhabdomyosarcoma; JQ1; ARMS; alveolar rhabdomyosarcoma; BRD; bromodomain; BET protein; bromo- and extra-Terminal protein; CI; combination index; ERMS; embryonal rhabdomyosarcoma; EV; empty vector; F
Diarylcyclopropane hydroxamic acid inhibitors of histone deacetylase 4 designed by combinatorial approach and QM/MM calculations
Keywords: Huntington's disease; Histone deacetylases; Inhibitors of HDAC4; Computer-assisted drug design; QM/MM approach; B3LYP; hybrid gradient-corrected exchange-correlation functional of electron density; CADD; computer-assisted drug design; DCHA; trans-(2R,3R)-
Reformation in chimeric antigen receptor based cancer immunotherapy: Redirecting natural killer cell
Keywords: NK cell; natural killer cell; IFN-γ; interferon-γ; IL; interleukin; TNF-α; tumor necrosis factor-α; CCL; C-C motif ligand; GM-CSF; granulocyte-macrophage colony-stimulating factor; ADCC; antibody dependent cell-mediated cytotoxicity; TRAIL; TNF-relate