Keywords: Fucosylated chondroitin sulfate; Glycosaminoglycan; Anticoagulant activity; Heparin cofactor II; Intrinsic factor Xase complex;
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Keywords: GAG; glycosaminoglycan; FG; fucosylated glycosaminoglycan; DFG; depolymerized fucosylated glycosaminoglycan; UFH; unfractionated heparin; LMWH; low-molecular-weight heparin; DD; deacetylation degree; GalNAc4S6S; 4,6-O-disulfated N-acetylgalactosamine; Glc
Structural analysis and biological activity of a highly regular glycosaminoglycan from Achatina fulica
Keywords: GAG; glycosaminoglycan; LMWH; low-molecular-weight heparin; DS; dermatan sulfate; TSP; trimethylsilyl-propionic acid; GlcA; glucuronic acid; GlcNAc; N-acetyl-2-deoxy-2-amino-glucose; IdoA; iduronic acid; IdoA2S; 2-sulfated iduronic acid; Mw; molecular wei
Genetic variants and evolutionary analyses of heparin cofactor II
Keywords: Heparin cofactor II; SerpinD1; Group V2; Synteny; Phylogenetic analysis; HCII variants; Nested gene; PIK4CA
Preparation, structure and anticoagulant activity of a low molecular weight fraction produced by mild acid hydrolysis of sulfated rhamnan from Monostroma latissimum
Keywords: Sulfated rhamnan; Depolymerization; Structure; Anticoagulant activity; Heparin cofactor II;
Fluorescent reporters of thrombin, heparin cofactor II, and heparin binding in a ternary complex
Keywords: Serpins; Heparin cofactor II; Thrombin inactivation; Heparin; Fluorescence equilibrium binding; Stopped-flow fluorescence;
An unexpected link between angiotensinogen and thrombin
Keywords: Angiotensin(ogen); Heparin cofactor II; Thrombin; Blood coagulation; Serpin;
A common standard is inappropriate for determining the potency of ultra low molecular weight heparins such as semuloparin and bemiparin
Keywords: aPTT; activated partial thromboplastin time; ACT; activated clotting time; AT; antithrombin; EP; European Pharmacopoeia; HCII; heparin cofactor II; HIT; heparin-induced thrombocytopenia; LMWHs; low molecular weight heparins; NHP; normal human plasma; PPP;
The dermatan sulfate-dependent anticoagulant pathway is mostly preserved in aneurysm and in severe atherosclerotic lesions while the heparan sulfate pathway is disrupted
Keywords: Dermatan sulfate; Chondroitin 4/6-sulfate; Heparan sulfate; Heparin cofactor II; Anti-thrombogenic activity of blood vessel;
Anticoagulant and anti-platelet activity of polyphenolic-polysaccharide preparation isolated from the medicinal plant Erigeron canadensis L.
Keywords: Anticoagulant activity; Anti-platelet activity; Medicinal plant; Polysaccharide complex; Plant glycoconjugates; Protamine sulfate; Heparin cofactor II
Heparin cofactor II (RbHCII) from rock bream (Oplegnathus fasciatus): Molecular characterization, cloning and expression analysis
Keywords: Heparin cofactor II; Serpin; Rock bream; Inhibitory activity; Anti-coagulation
Antithrombin and heparin cofactor II-mediated inactivation of α-thrombin by a synthetic, sulfated mannogalactan
Keywords: Sulfated polysaccharide; Mannogalactan; Pleurotus ostreatoroseus; Antithrombotic; Antithrombin; Heparin cofactor II
Highly sulfated dermatan sulfate from the skin of the ray Raja montagui: anticoagulant activity and mechanism of action
Keywords: Anticoagulant activity; Dermatan sulfate; Heparin cofactor II; Ray skin; Thrombin generation
Anticoagulant activity of a sulfated polysaccharide from the green alga Arthrospira platensis
Keywords: Anticoagulant activity; Arthrospira platensis; Calcium spirulan; Heparin cofactor II; Thrombin; Ultrafiltrated polysaccharide
Heparin cofactor II in atherosclerotic lesions from the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study
Keywords: Atherosclerosis; Immunohistochemistry; Heparin cofactor II; Thrombin; Serpins; PDAY
Mechanism of thrombin inhibition by heparin cofactor II and antithrombin in the presence of the ray (Raja radula) skin dermatan sulfate
Keywords: Kinetic model; Thrombin; Heparin cofactor II; Antithrombin; Dermatan sulfate; Ray skin;
Polysaccharides from the skin of the ray Raja radula. Partial characterization and anticoagulant activity
Keywords: Polysaccharides; Dermatan sulfate; Ray skin; Anticoagulant; Heparin cofactor II; Glycosaminoglycan
Characterization of a novel dermatan sulfate with high antithrombin activity from ray skin (Raja radula)
Keywords: Dermatan sulfate; Ray skin; 1H NMR; Anticoagulant effect; Heparin cofactor II; Antithrombin
Heparinoid-active two sulfated polysaccharides isolated from marine green algae Monostroma nitidum
Keywords: Monostroma nitidum; Sulfated polysaccharide; Chemical characteristic; Activated partial thromboplastin time; Thrombin time; Heparin cofactor II
Heparin cofactor II–thrombin complex: A biomarker of MPS disease
Keywords: Mucopolysaccharidosis; Enzyme replacement therapy; Biomarker; Heparin cofactor II; Thrombin; Lysosome; Glycosaminoglycan; Lysosomal storage disease
A sulfated fucan from the brown alga Laminaria cichorioides has mainly heparin cofactor II-dependent anticoagulant activity
Keywords: APTT; activated partial thromboplastin time; PT; prothrombin time; TT; thrombin time; Anticoagulant; Heparin cofactor II; Sulfated polysaccharide; Brown alga; Laminaria cichorioides;
Effect of oversulfated dermatan sulfate derivatives on platelet aggregation
Keywords: DS, dermatan sulfate; GAGs, glycosaminoglycans; AT, antithrombin; HCII, heparin cofactor II, GlcA, glucuronic acid; IdoA, iduronic acid; GalNAc, N-acetyl-galactosamine.Dermatan sulfate; Platelets; Aggregation; Heparin cofactor II; Antithrombin; Coagulatio
Decreased heparin cofactor II activity is associated with impaired endothelial function determined by brachial ultrasonography and predicts cardiovascular events
Keywords: Heparin cofactor II; Antithrombin III; Endothelial function; Coronary artery disease;
Insight into the profibrinolytic activity of dermatan sulfate: Effects on the activation of plasminogen mediated by tissue and urinary plasminogen activators
Keywords: Plm; plasmin; Plg; plasminogen; PA; plasminogen activators; t-PA; tissue plasminogen activator; u-PA; urinary plasminogen activator; DS; dermatan sulfate; GAG; glycosaminoglycan; MW; molecular weight; HC II; heparin cofactor II; EACA; 6-aminohexanoic acid
Heparin cofactor II–thrombin complex in MPS I: A biomarker of MPS disease
Keywords: Mucopolysaccharidosis; Iduronidase; iTRAQ; Biomarker; Serpin; Serine protease inhibitor; Heparan sulphate; Dermatan sulphate; Heparin cofactor II
Investigating serpin-enzyme complex formation and stability via single and multiple residue reactive centre loop substitutions in heparin cofactor II
Keywords: Serpins; Protease inhibitors; Thrombin; Heparin; Heparin cofactor II;
Dermatan sulfate is the predominant antithrombotic glycosaminoglycan in vessel walls: Implications for a possible physiological function of heparin cofactor II
Keywords: Vascular glycosaminoglycan; Anticoagulant glycosaminoglycan; Thrombosis; Dermatan sulfate; Heparan sulfate; Heparin cofactor II;