Keywords: AcOH; acetic acid; ACN; acetonitrile; APCI; atmospheric pressure chemical ionization; BSTFA; N,O-bis(trimethylsilyl)trifluoroacetamide; CBCA; cannabichromenic acid; CBC; cannabichromene; CBDA; cannabidiolic acid; CBD; cannabidiol; CBDVA; cannabidivarinic
مقالات ISI (ترجمه نشده)
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Keywords: CFU/mL; colony forming units per milliliter; FF; diphenylalanine; HFIP; hexafluoro-2-propanol; MBEC; minimum biofilm eradication concentration; NPN; N-phenyl-1-naphthylamine; Peptide; Biofilm; Infection; Nanotube; Drug delivery; Biomaterial;
Keywords: LC-MS; Liquid Chromatography Mass Spectrometry; CD; circular dichroism; ESR; Electron Spin Resonance; SPR; Surface Plasmon Resonance; CTD; C-terminal domain; NPM1; Nucleophosmin; LUV; Large Unilamellar Vesicle; AML; acute myeloid leukemia; HFIP; (1,1,1,
Keywords: Aβ; amyloid-β; AD; Alzheimer's disease; Ahx; aminohexanoic linker; EDC; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; fAD; familial form of AD; GPI; glycophosphatidylinositol; HBSS; Hank's balanced salt solution; HFIP; hexafluoro-2-propanol; LDH; lacta
Keywords: 1°amine; primary amine; 2°amine; secondary amine; 3°amine; tertiary amine; Ac; acetyl group; Alk; alkyl group; APTMS; aminopropyltrimethoxysilane; BF; base formulation; cP; centipoise; DABCO®; 1,4-diazobicyclo [2.2.2] octane; DBU; 1,8-diazabicyclo[5.4
Keywords: Alzheimer's disease; Ferulic acid-O-alkylamines derivatives; Multifunctional agents; Butyrylcholinesterase inhibition; Aβ aggregation; Antioxidant activity; Neuroprotective effects; BuChE; butyrylcholinesterase; AChE; acetylcholinesterase; Aβ; β-amyloi
Recent developments in enantioselective lanthanide-catalyzed transformations
Keywords: Ar; aryl; BINOL; 1,1â²-bi-2-naphthol; Bpy; 2,2â²-bipyridyl; Bn; benzyl; BNP; Binaphthophosphole; Boc; tert-butoxycarbonyl; BSA; bis-(trimethylsilyl)acetamide; CB; carbon black; cod; 1,5-cyclooctadiene; Cy; cyclohexyl; DBDMH; 1,3-dibromo-5,5-dimethylhyda
Keywords: RNCGDQLZIATDOU-ZDRBWGSPSA-N; ICYPJNZJUFGALC-PDTBJYIYSA-N; PDRMAVOIWIVXKH-SFUSBHMVSA-N; ISADXJRTBSLWPX-ZDRBWGSPSA-N; NLBLLPROASDPSC-QWWZWVQMSA-N; XKMIKZDBUOHHDK-ZDRBWGSPSA-N; BTURADNXKHTWGA-IJOLSIAMSA-N; UEKHRDLXBMZMPD-ZYIYBEKCSA-N; UQCLCXDOXVZEOA-JARUQAPT
Keywords: Polyglutamine; Huntington's disease; Disaggregation; Solubilization; Trifluoroacetic acid; Hexafluoroisopropanol; polyGln; polyglutamine; DMSO; dimethyl sulfoxide; TFA; trifluoroacetic acid; HFIP; hexafluoroisopropanol; ThT; thioflavin T; PBS; phosphate-b
Keywords: IAPP; islet amyloid polypeptide; hIAPP; human IAPP; DEPC; diethylpyrocarbonate; DMI; DEPC-modified hIAPP; HFIP; 1,1,1,3,3,3-hexafluoro-2-propanol; ThT; thioflavin-T; Modification; Amyloid; hIAPP; Imidazole ring;
Keywords: PLLA porous membrane; HFIP; Crystal behavior; Phase separation
Keywords: Sulfatase; Enzyme; Inhibitor; Estrogen; Cancer; SERM; ALP; alkaline phosphatase; DEA; diethylamine; DHEA; dehydroepiandrosterone; DHEAS; dehydroepiandrosterone sulfate; 5-diol; 5-androstene-3β,17β-diol; DIPEA; diisopropylamine; E1; estrone; E1S; estrone
Keywords: DMP; Dimethyl phthalate; DEP; Diethyl phthalate; DnBP; Di-n-butyl phthalate; DiBP; Di-isobutyl phthalate; BzBP; Benzylbutyl phthalate; DEHP; Di-2-ethylhexyl phthalate; DnPP; Di-n-pentyl phthalate; DPHP; Dipropylheptyl phthalate; DnOP; Di-n-octyl phthalate
Keywords: Ac; acetyl; acac; acetylacetonate; AHPCS; allylhydridopolycarbosilane; Bn; benzyl; Boc; tert-butoxycarbonyl; BPR; back pressure regulator; bpy; 2,2â²-bipyridine; Bu; butyl; CFL; compact fluorescent lamp; DCB; 1,4-dicyanobenzene; de; diastereomeric excess
Keywords: SPPS; solid phase peptide synthesis; DMF; dimethyl formamide; DIPEA; diisopropylethylamine; DIPC; diisopropylcarbodiimide; HOBt; 1-hydroxybenzotriazole; Fmoc; 9-fluorenylmethyloxycarbonyl; HFIP; 1,1,1,3,3,3-hexafluoropropan-2-ol; TFA; trifluoroacetic acid
Keywords: BCS; biopharmaceutics classification system; bFGF; basic fibroblast growth factor; BMC; bone morphogenetic protein; CA; cellulose acetate; CD; cyclodextrin; CS; chitosan; CS-EDTA; chitosan-ethylenediaminetetraacetic acid; CR; controlled release; DMAc;
Keywords: ANTS; 8-aminonaphtalene-1,3,6-trisulfonic acid sodium salt; DID; 1,1â²-dioctadecyl-3,3,3â²,3â²-tetramethyl-indodicarbocyanine; DPX; p-xylene-bis(pyridinium) bromide; GUVs; giant unilamellar vesicles; HFIP; 1,1,1,3,3,3-hexafluoro-2-propanol; LUVs; large
Keywords: Domino reaction; Michael addition; HFIP; Aniline; Heterocycles;
Concerted action of dipeptidyl peptidase IV and glutaminyl cyclase results in formation of pyroglutamate-modified amyloid peptides in vitro
Keywords: Amyloid beta peptides; Dipeptidyl peptidase IV; Enzyme-substrate interactions; Glutaminyl cyclase; MALDI-TOF mass spectrometry; Aβ; amyloid beta peptide; Aβ(1-40); amyloid beta peptide (1-40); Aβ(1-42); amyloid beta peptide (1-42); AD; Alzheimer's dise
Mechanistic analyses of the suppression of amyloid β42 aggregation by apomorphine
Keywords: Aβ; amyloid β-protein; AD; Alzheimer's disease; HFIP; 1,1,1,3,3,3,-hexafluoroisopropyl alcohol; HMQC; heteronuclear multiple quantum coherence; HPLC; high performance liquid chromatography; LC-MS; liquid chromatography-mass spectrometry; LC/Q Tof-MS
Anti-neuroinflammatory effects of SLOH in Aβ-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3β
Keywords: Aβ; Amyloid beta; AD; Alzheimer's disease; ANOVA; Analysis of variance; BBB; Blood-brain barrier; BCA; Bicinchoninic acid; BSA; Bovine serum albumin; COX-2; Cyclooxygenase-2; DAPI; 4â², 6-Diamidine-2â²-phenylindole dihydrochloride; DMEM; Dulbecco's m
Screening for amyloid-β aggregation inhibitor and neuronal toxicity of eight Tunisian medicinal plants
Keywords: Aβ42; β-Amyloid peptide 42; ABTS; 2â²-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid; AD; Alzheimer disease; BSA; bovine serum albumin; CD; Circular Dichroism; CM-H2 DCFDA; 2,7-dichlorofluorescin diacetate acetyl ester; CTX-B; cholera toxin subunit
Degradation of fibrin-β amyloid co-aggregate: A novel function attributed to ubiquitin
Keywords: AD; Alzheimer disease; AFM; atomic force microscopy; CAA; cerebral amyloid angiopathy; CHCA; α-cyano-4-hydroxycinnamic acid; DAPI; 4â²,6-diamidino-2-phenylindole; DMEM; Dulbecco's modified eagle medium; DMSO; dimethyl sulfoxide; ELISA; enzyme-linked imm
Apoptosis signal regulating kinase-1 and NADPH oxidase mediate human amylin evoked redox stress and apoptosis in pancreatic beta-cells
Keywords: ASK1; apoptosis signal regulating kinase-1; BME; β-mercaptoethanol; GSH; glutathione; hA; human amylin; hIAPP; human islet amyloid polypeptide; HFIP; hexafluoride isopropanol; JNK; c-Jun N-terminal kinase; Lac; lactacystin; MAP; mitogen activated protein
Exposure of the HIV-1 broadly neutralizing antibody 10E8 MPER epitope on the membrane surface by gp41 transmembrane domain scaffolds
Keywords: MPER; membrane-proximal external region; TMD; transmembrane domain; Env; HIV-1 envelope glycoprotein; MD; molecular dynamics; bNAb; broadly neutralizing antibody; CDR-H3; complementarity-determining region three of the heavy chain; HC; heavy chain; WT; wi
Up-regulation of NSP3 by Oligomeric Aβ Accelerates Neuronal Death Through Cas-independent Rap1A Activation
Keywords: aa; amino acid; Aβ; β-amyloid; AD; Alzheimer's disease; APP; amyloid precursor protein; CBD; Cas-binding domain; DIV; days in vitro; GEF; guanine nucleotide exchange factor; HFIP; 1,1,1,3,3,3-hexafluoro-2-propanol; NBD; NSP3-binding domain; NSP3; nove
Rationally designed divalent caffeic amides inhibit amyloid-β fibrillization, induce fibril dissociation, and ameliorate cytotoxicity
Keywords: Amyloid-β; Alzheimer's disease; Caffeic acid; Divalent caffeic amide; Inhibitor; Cytotoxicity; Aβ; amyloid-β; AD; Alzheimer's disease; CA; caffeic acid; CCS; collision cross-section; DMF; dimethylformamide; EDCI; 1-ethyl-3-(3-dimethylaminopropyl) carbo
Evolution of clinical and environmental health applications of exhaled breath research: Review of methods and instrumentation for gas-phase, condensate, and aerosols
Keywords: Breath research; Exhaled breath condensate (EBC); Exhaled breath aerosol (EBA); Volatile organic compounds (VOCs); Analytical techniques; Biomarkers; 1D; one-dimensional; ADME; absorption, distribution, metabolism, and excretion; AOP; adverse outcome path
From nano to micro to macro: Electrospun hierarchically structured polymeric fibers for biomedical applications
Keywords: 0-D; zero dimensional; 1-D; one dimensional; 2-D; two dimensional; 3-D; three dimensional; anti-EpCAM; anti-epithelial cell adhesion molecule; bFGF; basic fibroblast growth factor; BSHFs; bead-on-string heterostructured fibers; CFU; Colony-Forming Units;
Research articleKrüppel-like factor 4 regulates amyloid-β (Aβ)-induced neuroinflammation in Alzheimer's disease
Keywords: AD; Alzheimer's disease; Aβ; amyloid-β; Klf 4; Krüppel-like factor 4; TNF-α; tumor necrosis factor-a; IL-1β; interleukin-1β; iNOS; inducible nitric oxide synthase; COX-2; cyclooxygenase-2; CNS; central neural system; LPS; lipopolysaccharide; HFIP;
Modulation effect of acidulated human serum albumin on Cu2 +-mediated amyloid β-protein aggregation and cytotoxicity under a mildly acidic condition
Keywords: Amyloid β-protein; Copper ion; Albumin; Negative charge; Mildly acidic condition; Aggregation; Aβ; amyloid β-proteins; AD; Alzheimer's disease; A-HSA; acidulated human serum albumin; ROS; reactive oxygen species; HSA; human serum albumin; ThT; thioflav
UV-induced electron transfer between triethylamine and 5-bromo-2â²-deoxyuridine. A puzzle concerning the photochemical debromination of labeled DNA
Keywords: RP-HPLC; reverse phase high performance liquid chromatography; UHPLC; ultra high performance liquid chromatography; PAGE; polyacrylamide gel electrophoresis; TEAA; triethylamine acetate buffer solution; PCR; polymerase chain reaction; LC-MS; liquid chro
Design, synthesis and evaluation of scutellarein-O-acetamidoalkylbenzylamines as potential multifunctional agents for the treatment of Alzheimer's disease
Keywords: Alzheimer's disease; Scutellarein-O-acetamidoalkylbenzylamines; Multifunctional agents; Acetylcholinesterase inhibitors; Aβ aggregation inhibitors; Antioxidant agents; AD; Alzheimer's disease; AChE; acetylcholinesterase; ACh; acetylcholine; Aβ; β-amylo
Alzheimer's disease: How metal ions define β-amyloid function
Keywords: Aβ1â40; β-Amyloid, 40-residue isoform; Aβ1â42; β-Amyloid, 42-residue isoform; Aβ1â42/Aβ1â40; Ratio between levels of Aβ1â42 and Aβ1â40; ADAM; A Disintegrin And Metalloprotease, zinc peptidases, some being α-secretases; AICD; APP intra
Inhibition of amyloid fibril formation and cytotoxicity by caffeic acid-conjugated amyloid-β C-terminal peptides
Keywords: Aβ; amyloid-β; AD; Alzheimer's disease; CA; caffeic acid; DCFH-DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DHCA; dihydrocaffeic acid; DIPEA; N,N-diisopropylethylamine; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; Gly; glycine; HBTU; O
Research paperProtective effects of a Chotosan Fraction and its active components on β-amyloid-induced neurotoxicity
Keywords: CTS; chotosan; CTS-E; chotosan ethyl acetate fraction; AD; Alzheimer's disease; Aβ; β-amyloid; QTOFMS; quadrupole time-of-flight mass spectrometry; HFIP; 1,1,1,3,3,3-hexafluoro-2-propanol; ThT; thioflavon T; ROS; reactive oxygen species; DAD; diode ar
Nuclear magnetic resonance evidence for the dimer formation of beta amyloid peptide 1–42 in 1,1,1,3,3,3-hexafluoro-2-propanol
Keywords: Amyloid beta; HFIP; Solution NMR; Self-association; Alzheimer's diseaseAD, Alzheimer's disease; Aβ, amyloid beta; ThT, thioflavin T; NMR, nuclear magnetic resonance; HFIP, 1,1,1,3,3,3-hexafluoro-2-propanol; IB, inclusion body; HPLC, high-performance liqui
Fischer carbene mediated covalent grafting of a peptide nucleic acid on gold surfaces and IR optical detection of DNA hybridization with a transition metalcarbonyl label
Keywords: AFM; atomic force microscopy; DIPEA; diisopropylethylamine; HFIP; hexafluoroisopropanol; MBHA; 4-methylbenzylhydrylamine; MUA; 11-mercaptoundecanoic acid; NS; nanoshaving; PNA; peptide nucleic acid; ODN; oligonucleotide; PBS; phosphate buffered saline; PM
Aβ40 has a subtle effect on Aβ42 protofibril formation, but to a lesser degree than Aβ42 concentration, in Aβ42/Aβ40 mixtures
Keywords: Amyloid-beta protein; Aggregation; Protofibrils; Light scattering; AD; Alzheimer's disease; Aβ; amyloid-β protein; aCSF; artificial cerebrospinal fluid; DLS; dynamic light scattering; HFIP; hexafluoroisopropanol; RH; hydrodynamic radius; Rg; root mean s
Research reportAmyloid-β42 protofibrils are internalized by microglia more extensively than monomers
Keywords: AD; Alzheimer's disease; Aβ; amyloid-β protein; aCSF; artificial cerebrospinal fluid; HFIP; hexafluoroisopropanol; PBS; phosphate-buffered saline; SEC; size exclusion chromatography; TEM; transmission electron microscopy; TNFα; tumor necrosis factor α
Translocator protein ligands based on N-methyl-(quinolin-4-yl)oxypropanamides with properties suitable for PET radioligand development
Keywords: Translocator protein; PET; Carbon-11; Ligand; Binding affinity; Lipophilic efficiency; DIPEA; diisopropylethylamine; DMF; N,N-dimethylformamide; DMSO; dimethylsulfoxide; HFIP; hexafluoroisopropyl alcohol; HRMS-ESI; high resolution mass spectrometry electr
Oxidative stress and mitochondria-mediated cell death mechanisms triggered by the familial Danish dementia ADan amyloid
Keywords: Aβ; amyloid-β; AD; Alzheimer's disease; ANS; 8-anilinonapthalene-1-sulfonic acid; CAA; cerebral amyloid angiopathy; CAPS; 3-cyclohexamino-1-propanesulfonic acid; CD; circular dichroism; CNS; central nervous system; cyt c; cytochrome c; DCFDA; 2â²,7â²-
Aβ-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis
Keywords: Aβ; Amyloid β; AD; Alzheimer's disease; Akt; protein kinase B; AraC; cytosine arabinoside; ATP; adenosine triphosphate; CaM; calmodulin; CaMKIα; Ca2 +/calmodulin-dependent kinase type 1 alpha; CaMKII; Ca2 +/calmodulin-dependent kinase type II; CDK; c
Reconstitution and spectroscopic analysis of caveolin-1 residues 62-178 reveals that proline 110 governs its structure and solvent exposure
Keywords: DPC; dodecylphosphocholine; CD; circular dichroism; NMR; nuclear magnetic resonance; CPEG; cholesterol-PEG600; HFIP; 1,1,1,3,3,3-hexafluoroisopropanol; PEG; polyethylene glycol; Caveolin-1; Fluorescence spectroscopy; Circular dichroism spectroscopy; Topol
Synthetic study of peptide aldehyde via acetal/thioacetal transformation: application for Lys/Ser-containing peptides
Keywords: Peptide aldehyde; Acetal; Thioacetal; Cysteine protease inhibitor; SPPS; solid phase peptide synthesis; NBS; N-bromo succinimide; SARS; severe acute respiratory syndrome; DMF; dimethyl formamide; DIPEA; diisopropylethylamine; DIPC; diisopropylcarbodiimide
The p10 FAST protein fusion peptide functions as a cystine noose to induce cholesterol-dependent liposome fusion without liposome tubulation
Keywords: Îδ; secondary chemical shift; ARV; avian reovirus; bis-ANS; 4,4â²-dianilino-1,1â²-binaphthyl-5,5â²-disulfonic acid; Chol; cholesterol; CM; conserved motif; DTT; dithiothreitol; DMSO; dimethyl sulfoxide; DOPC; 2-dioleoyl-sn-glycero-3-phosphocholine; D
Non-fluorinated cosolvents: A potent amorphous aggregate inducer of metalloproteinase-conalbumin (ovotransferrin)
Keywords: ACN; acetonitrile; ANS; 1-anilino-8-napthalene sulfonate; CA; conalbumin; EtOH; ethanol; HFIP; 1,1,1,3,3,3-hexafluoro-propan-2-ol; MeOH; methanol; MG state; molecule globule state; SEM; scanning electron microscopy; TEM; transmission electron microscope;
Determination of NCO content of the urethane prepolymers by 19F NMR spectroscopy
Keywords: Urethane prepolymers; NCO content; 19F NMR; HFIP;
CD47 does not mediate amyloid-β(1-42) protofibril-stimulated microglial cytokine release
Keywords: AD; Alzheimer's disease; Aβ; amyloid-β protein; aCSF; artificial cerebrospinal fluid; HFIP; hexafluoroisopropanol; IL-1β; interleukin-1β; SEC; size exclusion chromatography; ThT; thioflavin T; TNFα; tumor necrosis factor α; Amyloid-beta protein; A
Molecular and cytotoxic properties of hIAPP17-29 and rIAPP17-29 fragments: A comparative study with the respective full-length parent polypeptides
Keywords: Spectroscopy; Type 2 diabetes; Confocal microscopy; Mitochondria; Amyloid; Model membranes; hIAPP; human islet amyloid polypeptide; IAPP; islet amyloid polypeptide; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; rIAPP; rodent islet amy