Keywords: ANA; antinuclear antibody; AIH; autoimmune hepatitis; AZA; azathioprine; HGPRT; hypoxanthine guanine phosphoribosyl transferase; IgG; immunoglobulin G; IBD; inflammatory bowel disease; LC; liver cytosol; LKM; liver kidney microsomal; 6MP; 6-mercaptopurine
مقالات ISI (ترجمه نشده)
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Keywords: VL; visceral leishmaniasis; PKDL; post-kala-azar dermal leishmaniasis; WHO; World Health Organization; TDR; Tropical Disease Research; HGPRT; hypoxanthine-guanine phosphoribosyltransferase; CDKs; cyclin dependent kinases; Leishmaniasis; Dose regimen; Drug
Keywords: A; Acetone extract; AAE; Water-acetone extract; AC; Alliun cepa; ACE; Acetate extract; AE; Aqueous extract; AEE; Hydroalcoholic extract; AI; Apoptosis-inducing; Ames; Bacterial reverse mutation assay; AN; Aspergillus nidulans; ANVISA; Agência Nacional
Keywords: A; adenine; ACMG; American College of Medical Genetics; Ala; alanine; Asp; aspartic acid; BCL2L12; B-cell lymphoma-2-like protein 12; BRCA1; breast cancer-1 gene; C; cytosine; CCDS; Consensus Coding Sequence; CD; circular dichroism; CDC; coding sequence;
Keywords: AZA; azathioprine; CDAI; Crohn's disease activity index; 95% CI; 95% confidence interval; CRP; C-reactive protein; CD; Crohn's disease; HGPRT; hypoxanthine-guanine phosphoribosyl transferase; HPLC; high performance liquid chromatography; IBD; inflammatory
Keywords: AAH; adenine aminohydrolase; APRT; adenine phosphoribosyltransferase; HGPRT; hypoxanthine-guanine phosphoribosyltransferase; XPRT; xanthine phosphoribosyltransferase; AK; adenosine kinase; dCF; 2â²-deoxycoformycin; ADSS; adenylosuccinate synthetase; EHNA
Keywords: Lesch-Nyhan disease; Variants; PRPP; Phenotype-genotype; HGprt; Molecular modeling;
Altered gastrointestinal motility in an animal model of Lesch-Nyhan disease
Keywords: ACh; Acetylcholine; CCh; Carbachol; SCH-23390; 7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride; DA; Dopamine; DAT; dopamine transporter; HGprt; hypoxanthine-guanine phosphoribosyltransferase; Iso; isoproterenol; EFS;
Oligomeric state of hypoxanthineâguanine phosphoribosyltransferase from Mycobacterium tuberculosis
Keywords: Mycobacterium tuberculosis; Hypoxanthineâguanine phosphoribosyltransferase; Enzyme activity; Oligomers; Three-dimensional structure; Structural biology; ANP; acyclic nucleoside monophosphonate; Ec; Escherichia coli; GMP; guanosine 5â²-monophosphate; HG
Liquid chromatography-mass spectrometry for measuring deoxythioguanosine in DNA from thiopurine-treated patients
Keywords: ALL; Acute childhood leukemia; 6-MP or MP; 6-mercaptopurine; AZA; azathioprine; IBD; inflammatory bowel disease; MeMP; methylmercaptopurine; MeMP-d3; Methymercaptopurine-D3; TIMP; thioinosine monophosphate; TIDP; thioinosine diphosphate; TITP; thioinosine
Establishment of correlation between in-silico and in-vitro test analysis against Leishmania HGPRT to inhibitors
Keywords: HGPRT; hypoxanthine-guanine phosphoribosyltransferase; HPRT; hypoxanthine phosphoribosyltransferase; APRT; adenosine phosphoribosyltransferase; XPRT; xanthine phosphoribosyltransferase; CL; cutaneous leishmaniasis; MCL; muco-cutaneous leishmaniasis; VL; v
GMP reductase and genetic uncoupling of adenylate and guanylate metabolism in Leishmania donovani parasites
Keywords: HGPRT; hypoxanthine-xanthine phosphoribosyltransferase; XPRT; xanthine phosphoribosyltransferase; dCF; 2â²-deoxycoformycin; ADSS; adenylosuccinate synthetase; ASL; adenylosuccinate lyase; IMPDH; IMP dehydrogenase; GMPR; GMP reductase; CBS; cystathionine-
Mechanisms involved in the antinociception induced by spinal administration of inosine or guanine in mice
Keywords: A1; adenosine receptor type 1; A2A; adenosine receptor type 2A; A3; adenosine receptor type 3; ADP; adenosine diphosphate; AMP; adenosine monophosphate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; AOPCP; É,β-methyleneadenosine 5â²-diph
ITPA (inosine triphosphate pyrophosphatase): From surveillance of nucleotide pools to human disease and pharmacogenetics
Keywords: Nucleotide pool; ITPA gene polymorphism; Pharmacogenetics; Base analogs; Mercaptopurines; Protein stability; Dominant negative; ITPA; inosine triphosphate pyrophosphatase; ITP; inosine triphosphate; XTP; xanthosine triphosphate; HAM1; Saccharomyces cerevi
S-allyl derivatives of 6-mercaptopurine are highly potent drugs against human B-CLL through synergism between 6-mercaptopurine and allicin
Keywords: 6-Mercaptopurine; Allicin; S-allyl thio-mercaptopurine; Pro-apoptotic; Induction of death in B-CLL cells; Human B-CLL in vivo model in mice; 6-MP; 6-mercaptopurine; 6-MPR; 6-mercaptopurine riboside; B-CLL; human B chronic lymphocytic leukemia; CLL; chroni
Human aldo-keto reductase AKR7A2 protects against the cytotoxicity and mutagenicity of reactive aldehydes and lowers intracellular reactive oxygen species in hamster V79-4 cells
Keywords: AKR; aldo-keto reductase; SSA; succinic semialdehyde; CBA; carboxybenzaldehyde; IC50; inhibitory concentration of 50% the cells; HNE; 4-hydroxynonenal; MTT; 3-(4,5-dimethylthiazoyl-2-yl)-2,5-diphenyltetrazolium bromide; NQ; naphthoquinone; HGPRT; hypoxa
Comparative modeling of HGPRT enzyme of L. donovani and binding affinities of different analogs of GMP
Keywords: HGPRT; hypoxanthine-guanine phosphoribosyl transferase; HPRT; hypoxanthine phosphoribosyltransferase; CL; cutaneous leishmaniasis; MCL; muco-cutaneous leishmaniasis; VL; visceral leishmaniasis; PKDL; post-kala-azar dermal leishmaniasis; BLAST; basic local
Heroin affects purine nucleotides metabolism in rat brain
Keywords: Purine nucleotides; Heroin; UA; ADA; XO; AK; HGPRT; APRT;
Short communicationPlasmodium vivax hypoxanthine-guanine phosphoribosyltransferase: A target for anti-malarial chemotherapy
Keywords: PRTase; phosphoribosyltransferase; PvHGPRT; Plasmodium vivax hypoxanthine-guanine-phosphoribosyltransferase; PfHGXPRT; Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase; HGPRT; hypoxanthine-guanine phosphoribosyltransferase; PR
Gender- and age-dependent changes in nucleoside levels in the cerebral cortex and white matter of the human brain
Keywords: 5â²NT; 5â²-nucleotidase; A1 receptors; A1 adenosine receptors; A2A receptors; A2A adenosine receptors; ADA; adenosine deaminase; Ado; adenosine; Gn; guanine; Guo; guanosine; HGPRT; hypoxanthine-guanine phosphoribosyltransferase; Hyp; hypoxanthine; Ino;
Acidic residues in the purine binding site govern the 6-oxopurine specificity of the Leishmania donovani xanthine phosphoribosyltransferase
Keywords: Phosphoribosyltransferase; Purine metabolism; HGPRT; XPRT; Leishmania
Hypoxanthine-guanine phosphoribosyltransferase from Mycobacteriumtuberculosis H37Rv: Cloning, expression, and biochemical characterization
Keywords: Mycobacterium tuberculosis; Purine salvage pathway; Hypoxanthine-guanine phosphoribosyltransferase; HGPRT; Protein purification; Kinetic parameters;
Characterization of a gene encoding alcohol dehydrogenase in benznidazole-susceptible and -resistant populations of Trypanosoma cruzi
Keywords: ADH; Alcohol dehydrogenase; BZ; Benznidazole; NFX; Nifurtimox; GST; Glutathione S-transferase; HGPRT; Hypoxanthine-guanine phosphoribosyltransferase; PCR; Polymerase chain reaction; PFGE; Pulsed field gel electrophoresis; TcADH; Trypanosoma cruzi alcoho
Further examination of the effects of nitrosylation on Alternaria alternata mycotoxin mutagenicity in vitro
Keywords: Alternaria alternata; Mycotoxin; Mutagenicity; Nitrosylation; Ames assay; HGPRT; Carcinogenesis; Genotoxicity; DNA damage
Association between Cigarette Smoking and Hypoxanthine Guanine Phosphoribosyltransferase Activity
Keywords: HGPRT; cigarette smoking; uric acid;
The 5â²-nucleotidases as regulators of nucleotide and drug metabolism
Keywords: 2,3-BPG; 2,3-bisphosphoglycerate; 3TCMP; 2â²-deoxy-3â²-thiacytidine monophosphate; 5-EddU; 5-ethynyl-dideoxyuridine; 5â²-NT; 5â²-nucleotidase; ADA; adenosine deaminase; AK; adenosine kinase; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukem