دانلود مقالات ISI درباره Hmgcr + ترجمه فارسی

A transcriptomic analysis of black cohosh: Actein alters cholesterol biosynthesis pathways and synergizes with simvastatin

Keywords: Actein; Black cohosh; Microarrays; Ranunculaceae; Simvastatin; Triterpene glycoside; CI; Combination Index; CYP; Cytochrome P450; DMSO; dimethylsulfoxide; DMEM; Dulbecco's Modified Eagle's medium; ERK; Extracellular signal related kinase; EtOH; ethanol; F

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

Profiles of β-Amyloid Peptides and Key Secretases in Brain Autopsy Samples Differ with Sex and APOE ε4 Status: Impact for Risk and Progression of Alzheimer Disease

Keywords: AD; Alzheimer disease; Aβ; β-amyloid; ADAM10; A disintegrin and metalloproteinase domain-containing protein 10/α-secretase (brain); APP; Amyloid Protein Precursor; APOE ε4; Apolipoprotein, allele epsilon4; BACE1; beta-site amyloid precursor protein cl

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

Long non-coding RNAs regulation in adipogenesis and lipid metabolism: Emerging insights in obesity

Keywords: lncRNAs; Obesity; White adipogenesis; Brown adipocyte differentiation; Lipid metabolism; Therapeutics; WAT; white adipose tissue; BAT; brown adipose tissue; Pparg; peroxisome proliferator-activated receptor γ; Cebpa; CCAAT/enhancer binding protein α; Fa

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

Complex lipid metabolic remodeling is required for efficient hepatitis C virus replication

Keywords: AA; arachidonic acid; ALA; α-linolenic acid; CD81; cluster of differentiation 81; CE; cholesterol ester; Cer; ceramides; Chol; cholesterol; CoA; coenzyme A; cPLA2; cytosolic phospholipases A2; DAG; diglycerides; DHA; docosahexaenoic acid; DMV; double-mem

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

A mathematical model of the mevalonate cholesterol biosynthesis pathway

Keywords: Nonlinear ordinary differential equation; Feedback; HMGCR; Squalene synthase;

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2018 سفارش ترجمه

Paving the Rho in cancer metastasis: Rho GTPases and beyond

Keywords: ADP; adenosine diphosphate; AMP; adenosine monophosphate; AMT; amoeboid-mesenchymal transition; APC; adenomatosis polyposis coli; Arp2/3; actin related protein 2/3; Cdc42; cell division control protein 42 homolog; CK1; casein kinase 1; COX-2; cyclooxygena

دانلود رایگان متن کامل مقاله ISI 73 صفحه سال انتشار : 2018 سفارش ترجمه

Short communicationPhosphorylation regulates activity of 7-dehydrocholesterol reductase (DHCR7), a terminal enzyme of cholesterol synthesis

Keywords: 7DHC; 7-dehydrocholesterol; AMPK; AMP-activated protein kinase; CaMKII; calmodulin-dependent kinase II; CHO; Chinese hamster ovary; CKI; casein kinase I; DHCR7; 7-dehydrocholesterol reductase; HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase; PBGD; porphob

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Sesame oil lignans inhibit hepatic endoplasmic reticulum stress and apoptosis in high-fat diet-fed mice

Keywords: CHOP; C/EBP homologous protein; CPT-1; carnitine palmitoyl transferase 1; ER; endoplasmic reticulum; FAS; fatty acid synthase; GC; gas chromatography; GRP78; 78-kDa glucose-regulated protein; HFD; high-fat diet; HMGCR; 3-hydroxy-3-methylglutaryl-CoA reduc

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Prenatal betaine exposure alleviates corticosterone-induced inhibition of CYP27A1 expression in the liver of juvenile chickens associated with its promoter DNA methylation

Keywords: SREBP; sterol regulator element-binding protein; HMGCR; 3-hydroxy-3-methylglutaryl coenzyme A reductase; CYP7A1; cholesterol-7alpha-hydroxylase; CYP27A1; cholesterol-27alpha-hydroxylase; ACAT1; acetyl-CoA cholesterol acyltransferase 1; LDLR; low density l

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Thyroid stimulating hormone exhibits the impact on LDLR/LDL-c via up-regulating hepatic PCSK9 expression

Keywords: SCH; subclinical hypothyroidism; TC; total cholesterol; LDL-c; low-density lipoprotein cholesterol; TSH; thyroid stimulating hormone; TSHR; thyroid stimulating hormone receptor; HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase; PCSK9; proprotein convertase

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Anti-hyperlipidemic effects of Rhizoma Coptidis alkaloids are achieved through modulation of the enterohepatic circulation of bile acids and cross-talk between the gut microbiota and the liver

Keywords: ASBT; apical sodium-dependent bile salt transporter; BSEP; bile salt export pump; COX2; cyclooxygenase 2; CYP7A1; cholesterol 7α-hydroxylase; FXR; farnesoid X receptor; HFHC; high fat and high cholesterol; HMGCR; 3-hydroxy-3-methyl glutaryl coenzyme A re

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Coenzyme Q10 protects against statin-induced myotoxicity in zebrafish larvae (Danio rerio)

Keywords: ATV; Atorvastatin; EM; embryo medium; HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase; hpf; hours post-fertilization; PTS; polyoxyethanyl-α-tocopheryl sebacate; Zebrafish; Larvae; CoQ10; Myotoxicity; Muscle atrophy; Mitochondria;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

EGCG ameliorates diet-induced metabolic syndrome associating with the circadian clock

Keywords: EGCG; Epigallocatechin gallate; CLOCK; Circadian locomotor output cycles kaput; BMAL1; Brain and muscle arnt-like protein-1; CRY; Cryptochromes; PER; Period; SIRT1; Sirtuin 1; PGC1α; Peroxisome proliferator-activated receptor coactivator 1-α; IR; Insuli

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Detection of autoantibodies to 3-hydroxy-3-methylglutaryl-coenzyme a reductase by ELISA in a reference laboratory setting

Keywords: ALBIA; Addressable laser bead assay; HMGCR; 3-Hydroxy-3-methylglutaryl-coenzyme A reductase; IIM; Idiopathic inflammatory myopathies; LIA; Line immunoassay; MAA; Myositis associated antibodies; MSA; Myositis specific antibodies; SARD; Systemic autoimmune

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2017 سفارش ترجمه

HMGCR inhibits the early stage of PCV2 infection, while PKC enhances the infection at the late stage*

Keywords: DMSO; dimethyl sulfoxide; FBS; fetal bovine serum; HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase; hpi; hours post infection; JNK1/2; Jun NH(2)-terminal kinase 1/2; kb; kilobase; MβCD; methyl-β-cyclodextrin; PBS; phosphate-buffered saline; PCR; polymer

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Metabolic roles of poly(ADP-ribose) polymerases

Keywords: ABCA1; ATP-binding cassette sub-family A member 1; ACACA; acetyl-CoA carboxylase alpha; ACBD3; acyl-CoA binding domain containing 3; ACLY; ATP citrate lyase; ADP; adenosine diphosphate; ADPR; ADP-ribose; AFLD; alcoholic fatty liver disease; AIF; apoptosis

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

New insights into cellular cholesterol acquisition: promoter analysis of human HMGCR and SQLE, two key control enzymes in cholesterol synthesis

Keywords: ChIP-seq; chromatin immunoprecipitation-sequencing; DHCR7; 7-dehydrocholesterol reductase; DHCR24; 24-dehydrocholesterol reductase; EMSA; electrophoretic mobility shift assay; FCLPDS; fetal calf lipoprotein-deficient serum; FCS; fetal calf serum; HMGCR; 3

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Suppression of brain cholesterol synthesis in male Mecp2-deficient mice is age dependent and not accompanied by a concurrent change in the rate of fatty acid synthesis

Keywords: 24S-OHC; 24(S)-hydroxycholesterol; Apoe; apolipoprotein E; CNS; central nervous system; Cyp27a1; cholesterol 27-hydroxylase; Cyp46a1; cholesterol 24-hydroxylase; Hmgcr; 3-hydroxy-3-methylglutaryl-CoA reductase; Mecp2; methyl CpG-binding protein 2; SC4mol;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Deletion of liver-specific STAT5 gene alters the expression of bile acid metabolism genes and reduces liver damage in lithogenic diet-fed mice

Keywords: STAT5; signal transducer and activator of transcription 5; GH; growth hormone; IGF-1; insulin-like growth factor-1; LDLR; low-density lipoprotein receptor; STAT5 LKO; liver-specific STAT5 knock-out; STAT5 fl/fl; STAT5 flox/flox; TG; triacylglycerol; ChMCs

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Steroidogenic acute regulatory protein (StAR) overexpression attenuates HFD-induced hepatic steatosis and insulin resistance

Keywords: StAR; steroidogenic acute regulatory protein; NAFLD; non-alcoholic fatty liver disease; HFD; high-fat diet; DMEM; Dulbecco's Modified Eagle Medium; PBS; phosphate buffered solution; FBS; fetal bovine serum; ITS-X; insulin-transferrin-selenium-ethanolamine

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperHMGCR is up-regulated in gastric cancer and promotes the growth and migration of the cancer cells

Keywords: GC; gastric cancer; HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase; ATCC; American Type Culture Collection; FBS; fetal bovine serum; GFP; green fluorescence protein; PBS; phosphate-buffered saline; Gastric cancer; HMGCR; Cell growth and migration; Hedgeh

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

HDL and microRNA therapeutics in cardiovascular disease

Keywords: ASO; antisense oligonucleotides; CAD; coronary artery disease; CVD; cardiovascular disease; DHCR7; 7-dehydrocholesterol reductase; HDL; high-density lipoproteins; HDL-C; HDL-cholesterol; HMGCS1; 3-hydroxy-3-methyl-glutaryl-CoA synthase 1; HMGCR; 3-hydroxy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Pleiotropic effects of antitumour alkylphospholipids on cholesterol transport and metabolism

Keywords: ABCA1; ATP-binding cassette transporter isoform A1; APL; alkylphospholipid; apoA1; apolipoprotein A1; CETP; cholesteryl ester transfer protein; CYP7A1; cholesterol 7α-hydroxylase; CYP27; sterol 27-hydroxylase; DHCR7; 7-dehydrocholesterol reductase; ER; e

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase

Keywords: cholesterol lowering; drug development; lipoproteins; Mendelian randomization; metabolomics; CVD; cardiovascular disease; HDL; high-density lipoprotein; HMGCR; HMG-CoA reductase; IDL; intermediate-density lipoprotein; LDL-C; low-density lipoprotein choles

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

The antihypercholesterolemic effect of columbamine from Rhizoma Coptidis in HFHC-diet induced hamsters through HNF-4α/FTF-mediated CYP7A1 activation

Keywords: COL; columbamine; TC; total cholesterol; TG; triglyceride; LDL-c; low-density lipoprotein cholesterol; HDL-c; high-density lipoprotein cholesterol; TBA; total bile acids; RC; Rhizoma Coptidis; HPLC; high-performance liquid chromatography; HMGCR; 3-hydroxy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Anti-HMGCR antibodies as a biomarker for immune-mediated necrotizing myopathies: A history of statins and experience from a large international multi-center study

Keywords: Autoimmune myositis; Autoantibodies; Immune-mediated necrotizing myopathy; HMGCR; Statins;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Synergetic cholesterol-lowering effects of main alkaloids from Rhizoma Coptidis in HepG2 cells and hypercholesterolemia hamsters

Keywords: Rhizoma Coptidis; Synergetic effect; Hypercholesterolemia; LDL receptor; HMGCR; CYP7A1;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

miRNA and cholesterol homeostasis

Keywords: miRNA; microRNA; SREBP; sterol regulatory element-binding protein; SCAP; SREBP cleavage-activating protein; Ago; Argonaute family protein; RISC; RNA-induced-silencing-complex; Fbxw7; F-box and WD repeat domain containing 7; NAFLD; non-alcoholic fatty live

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2016 سفارش ترجمه

SND1 overexpression deregulates cholesterol homeostasis in hepatocellular carcinoma

Keywords: ACAT; acyl-coenzyme A:cholesterol acyltransferase; CD; cyclodextrin; CE; cholesteryl ester; DMSO; dimethyl sulfoxide; ER; endoplasmic reticulum; FC; free cholesterol; HCC; hepatocellular carcinoma; HMGCR; hydroxymethylglutaryl-coenzyme A reductase; INSIG;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

Cyp3a deficiency enhances androgen receptor activity and cholesterol synthesis in the mouse prostate

Keywords: AR; androgen receptor; ARE; androgen response element; ChIP; chromatin immunoprecipitation; CYP3A; cytochrome P450 3A; Ddt; D-dopachrome tautomerase; Hmgcr; HMG-CoA reductase; Hmgcs1; HMG-CoA synthase 1; HPLC; high-performance liquid chromatography; Ldlr;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

DHCR7: A vital enzyme switch between cholesterol and vitamin D production

Keywords: 7DHC; 7-dehydrocholesterol; AEBS; antiestrogen binding site; DHCR7; 7-dehydrocholesterol reductase; DHCR14; Δ14-sterol reductase; DHCR24; 24-dehydrocholesterol reductase; EBP; emopamil binding protein; Hh; Hedgehog; HMGCR; 3-hydroxy-3-methylglutaryl-CoA

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNA-301a modulates doxorubicin resistance in osteosarcoma cells by targeting AMP-activated protein kinase alpha 1

Keywords: Osteosarcoma; MicroRNA-301a; AMPKα1; HMGCR; Doxorubicin; Drug resistance;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Modulation by geraniol of gene expression involved in lipid metabolism leading to a reduction of serum-cholesterol and triglyceride levels

Keywords: Geraniol; Hypolipemia; Lipogenesis; HMGCR; ACACAACACA, acetyl-CoA carboxylase; G, geraniol; HMG-CoA, 3-hydroxy-3-methylglutarylcoenzyme-A; HMGCR, 3-hydroxy-3-methylglutarylcoenzyme-A reductase; LDL, low-density-lipoprotein; LDLR, low-density-lipoprotein r

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Behavioral stress reduces RIP140 expression in astrocyte and increases brain lipid accumulation

Keywords: ABCA; ATP-binding cassette transporter; ABCG1; ATP-binding cassette sub-family G; ApoE; Apolipoprotein E; CYP46; cholesterol 24S-hydroxylase; CYP51; Sterol 14 alpha-demethylase; ER; endoplasmic reticulum; FSS; forced swim stress; H2O2; Hydrogen peroxide;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Dermatomyositis, polymyositis and immune-mediated necrotising myopathies

Keywords: BAFF; B cell-activating factor; BLTK; B lymphoid tyrosine kinase; CCL21; chemokine (C-C motif) ligand 2; CK; creatine kinase; DC; dendritic cell; CTD; connective tissue disease; DFS70; dense fine speckled 70; DM; dermatomyositis; HIV; human immunodeficien

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: Identification of mitochondrial fission factor as a new AMPK substrate

Keywords: AMPK; 5′-AMP-activated protein kinase; ACC; acetyl-CoA carboxylase; HMGCR; 3-hydroxy-3-methyl-glutaryl-CoA reductase; TBC1D1; TBC1 (tre-2/USP6, BUB2, cdc16) domain family member 1; ZO; zonula occludens.; Energy metabolism; Protein kinase; Cell signallin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

The 2014 ACR annual meeting: a bird’s eye view of autoimmunity in 2015

Keywords: Myositis; Connective tissue disease; Statins; Biomarker; HMGCR; Premature atherosclerosis; Prediction; 14-3-3η; Calprotectin; Leptin; Sjogren; MicroRNA; Neuropsychiatric lupus erythematosus; Mood disorder; B cell depletion; Fibromyalgia; Smoking; Citrulli

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Youngia denticulata attenuates diet-induced obesity-related metabolic dysfunctions by activating AMP-activated protein kinase and regulating lipid metabolism

Keywords: Youngia denticulata; Obesity; Fatty liver; Lipid accumulation; AMP-activated protein kinase; YDE; Youngia denticulata extract; ACC; acetyl-CoA carboxylase; AMPK; AMP activated protein kinase; SREBP1-c; sterol regulatory element-binding transcription facto

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

MYC and metabolism on the path to cancer

Keywords: 2-DG; 2-deoxyglucose; 4E-BP; eIF4E-binding protein; 5,10-methylene THF; 5,10-methylenetetrahydrofolate; ACC; acetyl-CoA carboxylase; ACLY; ATP-citrate lyase; AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; ChIP-seq; chromatin immunoprecip

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2015 سفارش ترجمه

Developmental processes regulated by the 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) pathway: Highlights from animal studies

Keywords: HMGCR; Statins; Toxicity; Development; Teratogenesis; Cholesterol; Prenylation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

1,3-Dichloro-2-propanol induced hyperlipidemia in C57BL/6J mice via AMPK signaling pathway

Keywords: 1,3-DCP; 1,3-dichloro-2-propanol; ACC; acetyl-CoA carboxylase; AMPK; adenosine 5′-monophosphate-activated protein kinase; FAS; fatty acid synthase; FAT; fatty acid translocase; FBS; fetal bovine serum; HMGCR; 3-hydroxy-3-methylglutaryl CoA reductase; p-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Ezetimibe enhances macrophage reverse cholesterol transport in hamsters: Contribution of hepato-biliary pathway

Keywords: RCT; reverse cholesterol transport; CETP; cholesterol ester transfer protein; BDL; bile duct ligation; TICE; transintestinal cholesterol efflux; LDLR; low-density lipoprotein receptor; ABCA1; ATP-binding cassette transporter A; NPC1L1; Niemann-Pick C1-l

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Deletion of PARP-2 induces hepatic cholesterol accumulation and decrease in HDL levels

Keywords: ABCA1; adenosine triphosphate-binding cassette transporter A1; ACACA; cetyl-CoA carboxylase alpha; ACLY; ATP citrate lyase; ACOX2; acyl-CoA oxidase 2; ARTD2; ADP-ribosyl transferase diphtheria toxin-like 2; cyp51A1; cytochrome P450, family 51 subfamily A,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Cholesterol biosynthesis and ER stress in peroxisome deficiency

Keywords: Peroxisomes; Cholesterol; Isoprenoid; Pex2; SREBP-2; ER stress; Integrated stress response; Unfolded protein response; Zellweger syndrome; ACAT; acetoacetyl-CoA thiolase; ATF; activating transcription factor; BA; bile acid; CHOP; C/EBP homologous protein;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Overexpression of JAZF1 protected ApoE-deficient mice from atherosclerosis by inhibiting hepatic cholesterol synthesis via CREB-dependent mechanisms

Keywords: TAK1/TR4; nuclear receptor subfamily 2, group C, member 2; EHC; euglycemic-hyperinsulinemic clamp; HFD; high fat diet; CREB; cAMP response element-binding protein; HMGCR; 3-hydroxy-3methylglutaryl coenzyme A reductase; JAZF1; Insulin resistance; Cholest

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Cytosolic functions of MORC2 in lipogenesis and adipogenesis

Keywords: MORC2; Microrchidia family CW-type zinc finger 2; ZF; zinc finger; IP; immunoprecipitation; ATP; adenosine triphosphate; ACLY; ATP citrate lyase; IBMX; 3-isobutyl-1-methylxanthine; GST; glutathione-S-transferase; RIPA; radio-immunoprecipitation assay; MDH

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Leishmania donovani activates SREBP2 to modulate macrophage membrane cholesterol and mitochondrial oxidants for establishment of infection

Keywords: PM; plasma membrane; ER; endoplasmic reticulum; SREBP2; sterol regulatory element binding protein 2; SCAP; SREBP cleavage activating protein; HMGCR; 3-hydroxy-3-methyl glutaryl CoA reductase; UCP2; uncoupling protein; ROS; reactive oxygen species; bHLH-Zi

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Overexpression of a key regulator of lipid homeostasis, Scap, promotes respiration in prostate cancer cells

Keywords: CHO; Chinese hamster ovary; ER; endoplasmic reticulum; FASN; fatty acid synthase; FCS; foetal calf serum; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HMGCR; HMG-CoA reductase; LDH; lactate dehydrogenase; LDLR; low-density lipoprotein receptor; MT-ND1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Pectin pentasaccharide from hawthorn (Crataegus pinnatifida Bunge. Var. major) ameliorates disorders of cholesterol metabolism in high-fat diet fed mice

Keywords: HMGCR; 3-hydroxy-3-methyl-glutaryl-CoA reductase; SREBP-2; sterol regulatory element-binding protein 2; LDLR; low density lipoprotein receptor; CYP7A1; cholesterol 7α-hydroxylase; ACAT; acyl-coenzyme A: cholesterol acyl-transferase; Actb; actin beta; HPP

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) pathway regulates developmental cerebral-vascular stability via prenylation-dependent signalling pathway

Keywords: HMGCR; Vasculature; Prenylation; Zebrafish; Statin; cdc42;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه