Keywords: Nitroalkene; Nitro-fatty acid; Electrophiles; Clinical trial; Preclinical development; Bardoxolone-me; Dimethyl fumarate; Nrf2; Nf-kB; Fibrosis; Inflammation; NO2-OA; nitro-oleic acid; NO2-FA; nitro-fatty acid; CXA-10; 10-nitro-oleic acid (10-nitro-octade
مقالات ISI (ترجمه نشده)
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Keywords: Nitroalkene fatty acid; Michael addition; Elimination; Thiols; Signaling; NO2-OA; nitro-oleic acid; NO2-LA; nitro-linoleic acid; NO2-AA; nitro-arachidonic acid; NO2-CLA; nitro-conjugated linoleic acid; GSH; glutathione; NF-κB; nuclear factor κB; Keap1;
Keywords: 17-AAG; 17-allylaminogeldanamycin; ATP; Adenosine triphosphate; AUC; Area under curve; DQ; Dequalinium; EPR; Enhanced permeation and retention effect; ER; Endoplasmic reticulum; GA; Geldanamycin; HSF-1; Heat shock factor 1; Hsp; Heat shock protein; HSR; H
Keywords: HFD; high fat diet; HOMA-IR; homeostasis model assessment-insulin resistance; Hsf-1; heat shock transcription factor 1; Hsp70; heat shock protein 70; NFD; normal fat diet; Nupr1; nuclear protein, transcriptional regulator, 1; T2D; type 2 diabetes; Islets
Keywords: Daphnia; Heat shock; Hsp70; HSF-1; Longevity; Aging;
HSP70 Facilitates Memory Consolidation of Fear Conditioning through MAPK Pathway in the Hippocampus
Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CAMK; Ca2+/calmodulin-dependent protein kinase; CFC; Contextual Fear Conditioning; CNS; central nervous system; CREB; cAMP responsive element-binding protein; ERK; extracellular signal-regulated
Phytochemicals-induced hormesis protects Caenorhabditis elegans against α-synuclein protein aggregation and stress through modulating HSF-1 and SKN-1/Nrf2 signaling pathways
Keywords: Caenorhabditis elegans; Dioscorea alata; Glyoxalase-1; Hormesis; HSF-1; SKN-1/Nrf2;
Glycogen synthase kinase 3β inhibition reduces mitochondrial oxidative stress in chronic myocardial ischemia
Keywords: metabolic syndrome; chronic coronary ischemia; glycogen synthase kinase 3B; oxidative stress; collagen; AIF; apoptosis inducing factor; CON; control group; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GSK-3β; glycogen synthase kinase- 3β; GSK-3βI;
Dependence of HSP27 cellular level on protein kinase CK2 discloses novel therapeutic strategies
Keywords: Protein kinase CK2; HSP27, SMURF2; Thermotherapy; Cancer; HSP; Heat shock protein; SMURF2; Smad ubiquitination regulatory factor 2; siRNA; small interfering RNA; PDCD5; Programmed cell death protein 5; CX-4945; (5-[(3-Chlorophenyl)amino]-benzo[c]-2,6-naph
Synergistic cellular responses to heavy metal exposure: A minireview
Keywords: MTF-1; metal-responsive transcription factor 1; MT; metallothioneins; NF-κB; nuclear factor κB; HSR; heat shock response; Zn; zinc; Cu; copper; Fe; iron; Cd; cadmium; ROS; reactive oxygen species; TNF-α; tumor necrosis factor α; IL-6; interleukin 6; P
Pro-apoptotic effects of lipid oxidation products: HNE at the crossroads of NF-κB pathway and anti-apoptotic Bcl-2
Keywords: AIF; Apoptosis inducing factor; ANT; Mitochondrial inner membrane protein adenine nucleotide translocase; Apaf-1; Apoptotic protease activating factor 1; BAG3; Bcl-2-associated athanogene domain 3; Bcl-2; B-cell lymphoma-2; HHE; 4-hydroxyhexenal; HNE; 4-H
Targeting chaperones, heat shock factor-1, and unfolded protein response: Promising therapeutic approaches for neurodegenerative disorders
Keywords: 17-AAG; 17-(allylamino)-17-demethoxygeldanamycin (tanespimycin); 17-DMAG; 17- dimethylaminoethylamino-17-demethoxygeldanamycin (alvespimycin); AAV; adeno-associated virus; Aβ; amyloid-β; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP;
Targeting heme oxygenase-1 and carbon monoxide for therapeutic modulation of inflammation
Keywords: ALI; acute lung injury; APCs; antigen-presenting cells; ARE; antioxidant responsive element; Bach1; Broad complex-Tramtrack-Bric-a-brac (BNB) and Cap'n'collar (CNC) homolog 1; BAL; bronchoalveolar lavage; BR; bilirubin-IXα; BV; biliverdin-IXα; BVR;
GSK3β-activation is a point of convergence for HIV-1 and opiate-mediated interactive neurotoxicity
Keywords: CNS; central nervous system; HIV-1; human immunodeficiency virus-1; HAND; HIV-1-associated neurocognitive disorders; cART; combination antiretroviral therapy; Tat; trans-activator of transcription; gp120; glycoprotein 120; GSK3β; glycogen synthase kinase
A ligand-entry surface of the nuclear receptor superfamily consists of the helix H3 of the ligand-binding domain
Keywords: hAR; human androgen receptor; hCAR; human constitutive androstane receptor; hCOUP-TFI; human chicken ovalbumin upstream promoter-transcription factor-I; hCOUP-TFII; human chicken ovalbumin upstream promoter-transcription factor-II; ssDAF-12; Strongyloides
Redox modulation of mitochondriogenesis in exercise. Does antioxidant supplementation blunt the benefits of exercise training?
Keywords: Akt; protein kinase B; AMPK; 5â²-AMP-activated protein kinase; AP-1; activator protein 1; COX IV; cytochrome c oxidase; CuZnSOD; copper/zinc superoxide dismutase; DMSO; dimethyl sulfoxide; eNOS; endothelial nitric oxide synthase; ERK; extracellular signa
Influence of vitamin C and vitamin E on redox signaling: Implications for exercise adaptations
Keywords: 5-LOX; 5-lipoxygenase; AP-1; activating protein 1; cGMP; cyclic guanosine monophosphate; ERK; extracellular signal-regulated kinase; GSH; glutathione (reduced); GSSG; glutathione (oxidized); H2O2; hydrogen peroxide; HIF-α; hypoxia inducible factor alpha;
Fluorodeoxyuridine enhances the heat shock response and decreases polyglutamine aggregation in an HSF-1-dependent manner in Caenorhabditis elegans
Keywords: FUdR; fluorodeoxyuridine; HSR; heat shock response; HS; heat shock; HSP; heat shock protein; HSF-1; heat shock factor 1; L4; larval stage 4; L1; larval stage 1; YA; young adult; D3; day 3 of adulthood; RNAi; RNA interference; qRT-PCR; quantitative real-ti
Mitochondrial EF4 links respiratory dysfunction and cytoplasmic translation in Caenorhabditis elegans
Keywords: C. elegans; Caenorhabditis elegans; WT; wild-type; EF4; elongation factor 4; mtEF4; mitochondrial EF4; mtDNA; mitochondrial DNA; BP; base pairs; ETC; electron transport chain; mtEFTu, mtEFG1 and mtEFTs; mitochondrial elongation factor Tu, G1 and Ts; MMP;
Pro-inflammatory cytokines downregulate Hsp27 and cause apoptosis of human retinal capillary endothelial cells
Keywords: HREC; human retinal endothelial cells; IDO; indoleamine 2,3-dioxygenase; MT; 1-methyl-dl-tryptophan; NOS; nitric oxide synthase; ROS; reactive oxygen species; TNF-α; tumor necrosis factor-α; IL-1β; interleukin-1β; IFN-γ; interferon-γ; VCAM-1; vascul
Long-term heat shock proteins (HSPs) induction by carbenoxolone improves hallmark features of Parkinson's disease in a rotenone-based model
Keywords: Oxidative stress; Ubiquitin proteasome system; Protein aggregation; α-Synuclein; Protein carbonylation; PD; Parkinson's disease; UPS; Ubiquitin proteasome system; HSPs; Heat shock proteins; Cbx; Carbenoxolone; HSF-1; Heat shock factor-1; TH; Tyrosine hyd
Considerations on regulatory sequences of the distal promoter region of the HLA-G gene
Keywords: CIITA; class II trans activator; EM; expectation maximization algorithm; GAS; interferon-gama activated site; HLA; human leucocyte antigen; HSE; heat shock element; HSF-1; heat shock factor 1; HWF>1%; haplotypes with frequency higher than 1%; INF; interfe
PI3-kinase/Akt/mTOR signaling: Impaired on/off switches in aging, cognitive decline and Alzheimer's disease
Keywords: AD; Alzheimer's disease; Aβ; amyloid-β; APP; amyloid precursor protein; 4EBP1; eukaryotic translation initiation factor 4E (eIF-4E)-binding protein-1; FOXO; Forkhead box-O class transcription factors; FMRP; Fragile-X mental retardation protein; GSK3β;
Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs
Keywords: ABCC; ATP-binding cassette, subfamily C; ARE; Antioxidant-response element; CA; carnosic acid; CS; Carnosol; DA; Dopamine; DMF; Dimethyl fumarate (also known as BG-12); DOX; Doxorubicin (also known as adriamycin); EP; Electrophile; GCLM; Glutamyl cysteine
Worms under stress: C. elegans stress response and its relevance to complex human disease and aging
Keywords: C. elegans; daf-16; hsf-1; complex human disease
Targeting the Heat Shock Response in Cancer
Keywords: Heat shock response; HSF-1; Curaxins; Small molecule inhibitors;
Variation in Hsp90, HSF-1, and hsp90 mRNA expression in tissues of pigs exposed to different durations of transport
Keywords: Hsp90; hsp90 mRNA; HSF-1; Transportation; Pig
Molecular actions and therapeutic potential of lithium in preclinical and clinical studies of CNS disorders
Keywords: Apoptosis; Brain-derived neurotrophic factor (BDNF); Glycogen synthase kinase 3 (GSK-3); Lithium; Neurodegenerative diseases; Neuroprotection; 3-NP; 3-nitropropionic acid; Aβ; β-amyloid; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; AP-1;
TC1 (C8orf4) is upregulated by cellular stress and mediates heat shock response
Keywords: TPA, 12-O-tetradecanoylphorbol 13-acetate; LPS, lipopolysaccharide; HSP, heat shock protein; HSF1, heat shock factor 1; NF-κB, Nuclear factor-kappaB; DMEM, Dulbecco’s modified Eagle’s mediumTC1(C8orf4); Heat shock; HSF-1; Cellular stress; Cancer; Gene exp
Characterization of Nrf2 activation and heme oxygenase-1 expression in NIH3T3 cells exposed to aqueous extracts of cigarette smoke
Keywords: AP-1; activated protein 1; ARE; antioxidant-responsive element; C/EBPβ; CAAT/enhancer-binding protein β; CNC/bZIP; “cap 'n' collar”/basic region-leucine zipper; CRE; cAMP-response element; CS; cigarette smoke; DMEM; Dulbecco's modified Eagle med
Anti-apoptotic Effects of L-Glutamine-Mediated Transcriptional Modulation of the Heat Shock Protein 72 During Heat Shock
Keywords: HSF-1; heat shock factor-1; Hsp72; heat shock protein 72; L-gln; L-glutamine; SEB; Staphylococcus aureus enterotoxin B;