Hsf4 counteracts Hsf1 transcription activities and increases lens epithelial cell survival in vitro
Keywords: Hsf4; Hsf1; Apoptosis; Lysosome and lens epithelial cell;
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Heat shock transcription factor HSF1 regulates the expression of the Huntingtin-interacting protein HYPK
Keywords: Chaperone; Gene expression; HSF1; HYPK; Stress response;
PP2A-AMPKα-HSF1 axis regulates the metal-inducible expression of HSPs and ROS clearance
Keywords: ROS; reactive oxygen species; HSPs; heat shock proteins; PP2A; protein phosphatase 2A; AMPKα; AMP-activated protein kinase α subunit; HSF1; heat shock transcription factor 1; NaAsO2; sodium arsenite; CdCl2; cadmium chloride; Heat shock proteins; Oxidati
Phosphorylation of heat shock protein 40 (Hsp40/DnaJB1) by mitogen-activated protein kinase-activated protein kinase 5 (MK5/PRAK)
Keywords: CREB, cAMP response element binding protein; HSF, heat shock factor; HSP, heat shock protein; MK, mitogen-activated protein kinase-activated protein kinase; PK, protein kinase; PKA, cAMP-dependent protein kinase/protein kinase AMAPKAPK-5; PRAK; HSF1; ATP
Molecular cloning, characterization and expression analysis of three heat shock responsive genes from Haliotis diversicolor
Keywords: Haliotis diversicolor; HSF1; HSBP1; HSP90; Stress
Lens specific RLIP76 transgenic mice show a phenotype similar to microphthalmia
Keywords: RLIP76; lens development; microphthalmia; Hsf1; Hsf4b; Pax6; Cdc42; cytoskeleton organization
Inhibitory effect of atorvastatin on AGE-induced HCAEC apoptosis by upregulating HSF-1 protein
Keywords: AGEs; HSF1; HSP70; CHD; RT-PCR;
Heat shock transcription factor 1 attenuates TNFα-induced cardiomyocyte death through suppression of NFκB pathway
Keywords: HSF1; Heat shock transcription factor 1; NFκB; Nuclear factor-κB; TNFα; tumor necrosis factor alpha; HSP70; heat shock proteins 70; HSP90; heat shock proteins 90; RelA; v-rel reticuloendotheliosis viral oncogene homolog A; RHD; Rel Homology Domain; NLS
Activation of the antioxidant response in methionine deprived human cells results in an HSF1-independent increase in HSPA1A mRNA levels
Keywords: Heat shock factor 1; Amino acid deprivation; Methionine; DNAJB1; NRF2; GCN2; general non-derepressible 2; ATF; activating transcription factor; ASNS; asparagine synthetase; SAM; S-adenosylmethionine; HMOX1; heme oxygenase 1; GSTP; glutathione S-transferas
Rim15-dependent activation of Hsf1 and Msn2/4 transcription factors by direct phosphorylation in Saccharomyces cerevisiae
Keywords: Hsf1; Msn2/4; Phosphorylation; PKA; Rim15;
Symplekin, a polyadenylation factor, prevents MOZ and MLL activity on HOXA9 in hematopoietic cells
Keywords: AMLs; acute myeloid leukemias; BRPF; bromodomain and PHD finger-containing protein; CPSF100; cleavage and polyadenylation specificity factor 100; CTD-RNA-PolII; C-terminal domain of the RNA-polymerase II; EAF6; Esa1-associated factor 6 ortholog; HAT; hist
Inhibition of C2C12 myotube atrophy by a novel HSP70 inducer, celastrol, via activation of Akt1 and ERK1/2 pathways
Keywords: Celastrol; Countermeasure; Dexamethasone; HSF1; HSP72; Muscle atrophy;
N-Acetyl cysteine blunts proteotoxicity in a heat shock protein-dependent manner
Keywords: ANOVA; analysis of variance; HO-1; heme oxygenase 1; HSF1; heat shock factor 1; Hsc70; heat shock cognate 70; Hsp70; heat shock protein 70; PBS; phosphate-buffered saline; Parkinson's disease; Alzheimer's disease; heat shock protein 70; heat shock cog
Geranylgeranylacetone suppresses noise-induced expression of proinflammatory cytokines in the cochlea
Keywords: ABR; auditory brainstem response; GGA; geranylgeranylacetone; HSF1; heat shock transcription factor 1; Hsp; heat shock protein; IL-6; interleukin-6; IL-1β; interleukin-1β; TNF-α; tumor necrosis factor α; Heat shock proteins; Noise exposure; Inflammati
Sulphoraphane, a naturally occurring isothiocyanate induces apoptosis in breast cancer cells by targeting heat shock proteins
Keywords: HSP; HSF1; Sulphoraphane; Apoptosis; Breast cancer cells
Expression of heat shock transcription factor 1 and its downstream target protein T-cell death associated gene 51 in the spinal cord of a mouse model of amyotrophic lateral sclerosis
Keywords: ALS, Amyotrophic lateral sclerosis; MNs, Motor neurons; FALS, Familial ALS; SOD1, Cu/Zn-superoxide dismutase 1; HSP70, Heat shock protein 70; HSF1, Heat shock transcription factor 1; TDAG51, T-cell death associated gene 51ALS; HSF1; TDAG51; HSPs
Association of Stat3 with HSF1 plays a critical role in G-CSF-induced cardio-protection against ischemia/reperfusion injury
Keywords: Cardiomyocytes; G-CSF; HSF1; Ischemia/reperfusion injury; Stat3;
Toward understanding Machado-Joseph disease
Keywords: ATXN3; ataxin-3; bZIP; basic leucine zipper motif; CBPC; REB binding protein; cDNA; complementary DNA; CHIP; C-terminus of Hsc70 interacting protein; CK2; casein kinase 2; CMV; cytomegalovirus; CNS; central nervous system; CREB; cAMP-response element bind
Activation of the heat shock transcription factor Hsf1 is essential for the full virulence of the fungal pathogen Candida albicans
Keywords: Candida albicans; Heat shock; Hsf1; Transcriptional activation; Phosphorylation; Pathogenesis;
The driver of malignancy in KG-1a leukemic cells, FGFR1OP2–FGFR1, encodes an HSP90 addicted oncoprotein
Keywords: Chromosomal translocation; FGFR1 fusion oncoprotein; Tyrosine kinase; HSP90; CDC37; HSF1; Malignant phenotype
Heat shock transcription factor 1 protects heart after pressure overload through promoting myocardial angiogenesis in male mice
Keywords: Angiogenesis; Cardiac hypertrophy; Endothelial cell; HSF1; Pressure overload
Biotinylated quercetin as an intrinsic photoaffinity proteomics probe for the identification of quercetin target proteins
Keywords: RDBGOPDIMUUTST-HSAZJEJNSA-N; Quercetin; Photoaffinity probe; Biotinylated pull down probe; Heat shock proteins; ATP binding proteins; Casein kinase 2; BSA; bovine serum albumin; CaMK2; Ca2+/calmodulin-dependent protein kinase II; CK2; casein kinase II; CO
Lipidomics reveals membrane lipid remodelling and release of potential lipid mediators during early stress responses in a murine melanoma cell line
Keywords: AA; arachidonic acid; BA; benzyl alcohol; CE; cholesteryl ester; Cer; ceramide; Chol; cholesterol; DAG; diacylglycerol; ESI-MS/MS; electrospray ionization tandem mass spectrometry; FA; fatty acid; FAAH; fatty acid amide hydrolase; FAME; fatty acid methyl
Pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione derivatives as novel small molecule chaperone amplifiers
Keywords: Small molecule chaperone amplifiers; Protein misfolding; HSF1; Heat shock proteins (HSPs); Stress granule; Rotenone stress; OGD; Neurodegenerative diseases; Cytoprotection; Pyrimidotriazinedione derivatives;
Analysis of Msx1 and Msx2 transactivation function in the context of the heat shock 70 (Hspa1b) gene promoter
Keywords: Msx1; Msx2; Transcriptional activator; Hsp70; Hspa1b; Promoter analysis; Protein–protein interaction; Homeodomain; Heat shock factor; HSF1; HSF2; Heat shock elements; HSE; Co-transfection; Mutagenesis; Immunoprecipitation
Basal behavioral characterization of hsf1 deficient mice and its cellular and behavioral abnormalities underlying chronic unpredictable stressors
Keywords: hsf1; T-CAT; KO mice; Stressor; Anxiety; Hippocampal; Locomotor; Apoptosis
Self-regulatory role of 4-hydroxynonenal in signaling for stress-induced programmed cell death
Keywords: HNE; 4-hydroxynonenal; RalBP1; Ral-binding protein1; Daxx; death-associated protein; HSF1; heat shock factor 1; HSP; heat shock proteins; GST; glutathione S-transferases, ASK1, apoptosis signaling kinase 1; JNK; c-jun N-terminal kinase.; 4-Hydroxynonenal;
Neural differentiation and the attenuated heat shock response
Keywords: dibutyryl cAMP; N6,2â²-O-dibutyryl adenosine 3â²:5â²-cyclic mono-phosphate; FBS; fetal bovine serum; HSF1; heat shock factor 1; HSR; heat shock response; HSP; heat shock protein; HSP70; the 72Â kDa heat shock protein; HSC70; the 73Â kDa constitutively
HSF1 and constitutively active HSF1 improve vascular endothelial function (heat shock proteins improve vascular endothelial function)
Keywords: HSF1; Heat shock protein; Endothelium; PAI-1; Endothelin-1; eNOS; Thrombomodulin
Research ReportPharmacological induction of heat shock protein exerts neuroprotective effects in experimental intracerebral hemorrhage
Keywords: GGA; geranylgeranylacetone; DMSO; dimethyl sulfoxide; DMEM; Dulbecco's modified Eagle's medium; eNOS; endothelial nitric oxide synthase; HSF1; heat shock factor-1; HSP; heat shock protein; ICH; intracerebral hemorrhage; IL-6; interleukin-6; MIP-1; macroph
Inhibitors of the heat shock response: Biology and pharmacology
Keywords: HSP90; HSP70; HSF1; Heat shock response; Inhibitor17-AAG, 17-allylamino-17-demethoxygeldanamycin; 17-DMAG, 17-dimethylaminoethylamino-17-demethoxygeldanamycin; HSP, heat shock protein; HSR, heat shock response; TPR, tetracopeptide repeat
Cross talk of heat shock and heavy metal regulatory pathways
Keywords: Heavy metal; Cadmium; Zinc; Metallothionein; Heat shock protein 70; MTF-1; HSF1; Transcriptional repression; Protein–protein interaction
Simvastatin induces heat shock factor 1 in vascular endothelial cells
Keywords: Statin; HSF1; Heat shock proteins; Endothelium; PAI-1; Endothelin-1; eNOS; Thrombomodulin
Geranylgeranylacetone, a heat shock protein inducer, prevents acoustic injury in the guinea pig
Keywords: System neuroscience-(b) sensory and motor systems; Auditory, vestibular, and lateral line: periphery; GGA; geranylgeranylacetone; Hsp; heat shock protein; Hsps; heat shock proteins; ABR; auditory brainstem response; HSF1; heat shock transcriptional fact
Cloning and characterization of the hsp70 multigene family from silver sea bream: Modulated gene expression between warm and cold temperature acclimation
Keywords: Fish; Temperature; hsc70; hsp70; hsf1; IGF-1; Hormones;
Dominant-positive and dominant-negative heat shock factors
Keywords: Heat shock factor; Dominant-positive; Dominant-negative; HSF; HSF1; Gene switches; Cancer therapy; Immunogenicity; Cytoprotection; Apoptosis;
Arsenic trioxide induces Hsp70 expression via reactive oxygen species and JNK pathway in MDA231 cells
Keywords: Arsenic trioxide; Hsp70; HSF1; ROS; NAC; JNK