Keywords: HSV، ویروس هرپس سیمپلکس; Herpes simplex virus reactivation; Trigeminal neuralgia surgeryCNS, Central nervous system; HSV, Herpes simplex virus; MS, Multiple sclerosis; PCR, Polymerase chain reaction; TN, Trigeminal neuralgia
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Keywords: HSV، ویروس هرپس سیمپلکس; BS, brassinosteroids; CC50, 50% cytotoxic concentration; EBl, 24-epibrassinolide; EC50, half maximal effective concentration; HSV, herpes simplex virus; HBl, 28-homobrassinolide; MPP+, 1-methyl-4-phenylpyridinium; TNF-α, tumor necrosis factor αBrassinoste
Keywords: HSV، ویروس هرپس سیمپلکس; BE, bioequivalence; CMA, critical material attributes; CPP, critical process parameters; CQA, critical quality attributes; DoE, design of experiments; HSV, herpes simplex virus; ICH, international conference on harmonisation; IVRT, in vitro release testin
Keywords: HSV، ویروس هرپس سیمپلکس; DILI, drug-induced liver injury; EBV, Epstein–Barr virus; CMV, cytomegalovirus; HIV, human immunodeficiency virus; HSV, herpes simplex virus; HAV, hepatitis A virus; HBsAg, hepatitis B surface antigen; HBcAb, hepatitis B core antibody; HCV, hepatitis C vi
Keywords: HSV، ویروس هرپس سیمپلکس; ADEM, acute disseminated encephalomyelitis; CRP, C-reactive protein; CSF, cerebrospinal fluid; CT, computed tomography; HSE, herpes simplex encephalitis; HSV, herpes simplex virus; IgG, immunoglobulin G; IgM, immunoglobulin M; MRI, magnetic resonance imag
Keywords: HSV، ویروس هرپس سیمپلکس; HLH, haemophagocytic lymphohistiocytosis; FHLH, familial haemophagocytic lymphohistiocytosis; ALF, acute liver failure; GALD, gestational alloimmune liver disease; HSV, herpes simplex virus; TMS, tandem mass spectrometry; PALF, paediatric acute liver fail
Secretory leukocyte protease inhibitor (SLPI), a multifunctional protein in the host defense response
Keywords: HSV، ویروس هرپس سیمپلکس; AHR, airway hyperresponsiveness; ALS, amyotrophic lateral sclerosis; CHIP, chromatin immunoprecipitation; CNS, central nervous system; COX, cyclooxygenase; HMG-1, high-mobility group 1; HSV, herpes simplex virus; ECM, extracellular matrix; IGFBP-3, insuli
IL-2/IL-2 antibody immune complex regulates HSV-induced inflammation through induction of IL-2 receptor alpha, beta, and gamma in a mouse model
Keywords: HSV، ویروس هرپس سیمپلکس; BD, Behçet’s disease; BDN, BD normal; HSV, herpes simplex virus; IL-2/S4B6-1, IL-2/anti-mIL-2 antibody complex; IL-2R, interleukin-2 receptor; ip, intraperitoneal; LN, lymph node; NK, natural killer; PBMC, peripheral blood mononuclear cells; PBS, phosphat
Detection and identification of viral pathogens in patients with hand, foot, and mouth disease by multilocus PCR, reverse-transcription PCR and electrospray ionization mass spectrometry
Keywords: HSV، ویروس هرپس سیمپلکس; RT-PCR/ESI-MS, reverse transcription-PCR coupled with electrospray ionization mass spectrometry; HFMD, hand, foot and mouth disease; EV, enterovirus; CVA, coxsackievirus A; ECHO, echovirus; CSF, cerebrospinal fluid; HSV, herpes simplex virus; VZV, varicel
Identification of two novel functional p53 responsive elements in the herpes simplex virus-1 genome
Keywords: HSV، ویروس هرپس سیمپلکس; 5-FU, 5-fluorouracil; ChIP, chromatin immunoprecipitation; EMSA, electrophoretic mobility shift assay; FBS, fetal bovine serum; HSV, herpes simplex virus; IE, immediate early; moi, multiplicity of infection; PBS, phosphate buffered saline; RE, responsive
The bidirectional p53–Wrap53β promoter is controlled by common cis- and trans-regulatory elements
Keywords: HSV، ویروس هرپس سیمپلکس; bp, base pairs; E. coli, Escherichia coli; EDTA, ethylenediaminetetraacetic acid; EMSA, electrophoretic mobility shift assay; FBS, fetal bovine serum; h, hour; HSV, herpes simplex virus; Nspc, non-specific competitor; Nuc, nucleotide; S phase, synthesis p
The HLA-G low expressor genotype is associated with protection against bipolar disorder
Keywords: HSV، ویروس هرپس سیمپلکس; Bp, base pair; BD, bipolar disorder; CTLA4, cytotoxic T lymphocyte antigen 4; CI, confidence interval; EBV, Epstein-Barr virus; CMV, cytomegalovirus; HSV, Herpes simplex virus; HERV-W, human endogenous retrovirus-W; HTLV-1, human T cell leukemia/lymphoma
Why is eczema herpeticum unexpectedly rare?
Keywords: HSV، ویروس هرپس سیمپلکس; AD, atopic dermatitis; ADEH+, AD with a history of eczema herpeticum; ADEH, AD without a history of eczema herpeticum; CLDN, claudin; EH, eczema herpeticum; FLG, gene encoding filaggrin; HSV, herpes simplex virus; IFN, interferon; PBMC, peripheral blood m
Cyclin D1/Cdk4 increases the transcriptional activity of FOXM1c without phosphorylating FOXM1c
Keywords: HSV، ویروس هرپس سیمپلکس; aa, amino acid; Cdk, cyclin-dependent kinase; CKI, Cdk inhibitor; CMV, cytomegalovirus; DBD, DNA binding domain; dn, dominant-negative; FOXM1c, Forkhead box M1, splice variant c; GST, glutathione-S-transferase; HA, hemagglutinin; HSV, herpes simplex virus
JAB1/CSN5 inhibits the activity of Luman/CREB3 by promoting its degradation
Keywords: HSV، ویروس هرپس سیمپلکس; ER, endoplasmic reticulum; ERAD, ER-associated degradation; HSV, herpes simplex virus; UPR, unfolded protein response; UPRE, unfolded protein responseLuman/CREB3/LZIP; JAB1/CSN5; Unfolded protein response; Protein degradation; Transcription factor
Inhibition of herpes simplex virus type 1 with the modified green tea polyphenol palmitoyl-epigallocatechin gallate
Keywords: HSV، ویروس هرپس سیمپلکس; HSV, herpes simplex virus; HSV-1, herpes simplex virus type 1; HSV-2, herpes simplex virus type 2; EGCG, epigallocatechin gallate; p-EGCG, palmitoyl-EGCG; GFP, green fluorescent protein; DAPI, 4,6-diamidino-2-phenylindoleHSV-1; Vero cells; EGCG; Palmitoyl
Herpesviruses and the microbiome
Keywords: HSV، ویروس هرپس سیمپلکس; Hygiene hypothesis; genomics; microbiome; herpes; therapy; vaccinesCMV, Cytomegalovirus; DRESS, Drug reaction with eosinophilia and systemic symptoms; EBNA, Epstein-Barr nuclear antigen; HSV, Herpes simplex virus; HSV1, Herpes simplex virus type 1, also k
Oncolytic virus therapy for cancer: the first wave of translational clinical trials
Keywords: HSV، ویروس هرپس سیمپلکس; CEA, carcinoembryonic antigen; GMCSF, granulocyte-macrophage colony stimulating factor; HSV, herpes simplex virus; MV, measles virus; MV-NIS, MV that expresses the sodium-iodide symporter; MV-CEA, MV vaccine strain carrying the human CEA gene; pfu, plaque
Synthesis and broad spectrum antiviral evaluation of bis(POM) prodrugs of novel acyclic nucleosides
Keywords: HSV، ویروس هرپس سیمپلکس; Nucleosides; Synthesis; Olefin cross metathesis; Antiviral properties; Modified heterocyclesVZV, varicella zoster virus; VV, vaccinia virus; HSV, herpes simplex virus; VSV, vesicular stomatitis virus; DNA, deoxyribonucleic acid; RNA, ribonucleic acid; CC5
The Tiers and Dimensions of Evasion of the Type I Interferon Response by Human Cytomegalovirus
Keywords: HSV، ویروس هرپس سیمپلکس; HCMV, human cytomegalovirus; dsDNA, double-stranded DNA; HSV, Herpes Simplex virus; HIV, human immunodeficiency virus; PRR, pattern recognition receptor; ISG, IFN-stimulated gene; NK, natural killer; MCMV, murine cytomegalovirus; IRF, IFN regulatory facto
T cell-based gene therapy of cancer
Keywords: HSV، ویروس هرپس سیمپلکس; CAR, chimeric antigen receptors; GM-CSF, Granulocyte-macrophage colony-stimulating factor; HSV, Herpes simplex virus; IL, interleukin; INF, Interferon; MHC, Major Histocompatibility Complex; qPCR, quantitative polymerase chain reaction; scFv, single chain
Antiviral Mechanisms of Human Defensins
Keywords: HSV، ویروس هرپس سیمپلکس; CMV, cytomegalovirus; HD, human defensin; HIV, human immunodeficiency virus; HPIV, human parainfluenza virus; HSV, herpes simplex virus; IAV, influenza A virus; RSV, respiratory syncytial virus; VSV, vesicular stomatitis virus; PIV, parainfluenza virus; H
Absence of viruses in amniotic fluid of women with PPROM: a case series
Keywords: HSV، ویروس هرپس سیمپلکس; PPROM, preterm premature rupture of membranes; HSV, herpes simplex virus; AAV-2, adeno-associated virus 2; HPV, human papilloma virus; CMV, cytomegalovirus; GBS, group B streptococcus; C, Celsius; cc, cubic centimeter; MgCl2, magnesium chloride; WBC, whit
Mitochondria-derived reactive oxygen species negatively regulates immune innate signaling pathways triggered by a DNA virus, but not by an RNA virus
Keywords: HSV، ویروس هرپس سیمپلکس; ROS, reactive oxygen species; HSV, herpes simplex virus; SeV, Sendai virus; TLR, Toll-like receptor; DNAR, DNA receptor; RIG-I, retinoic acid inducible gene I; RLR, RIG-I-like receptor; ETC, electron transport chain; NOX, NADPH-oxidaseInnate immunity; Rea
The carboxyl-terminal region of Crtac1B/LOTUS acts as a functional domain in endogenous antagonism to Nogo receptor-1
Keywords: HSV، ویروس هرپس سیمپلکس; AP, alkaline phosphatase; CNS, central nervous system; Crtac1B, cartilage acidic protein-1B; DMEM, Dulbecco’s modified Eagle’s medium; DRG, dorsal root ganglion; EGF, epidermal growth factor; GPI, glycosylphosphatidylinositide; HSV, herpes simplex virus;
A new highly automated extraction system for quantitative real-time PCRs from whole blood samples: Routine monitoring of opportunistic infections in immunosuppressed patients
Keywords: HSV، ویروس هرپس سیمپلکس; IQC, intra-laboratory quality control; QCMD, Quality Control for Molecular Diagnosis; CMV, cytomegalovirus; EBV, Epstein–Barr virus; HIV, human immunodeficiency virus; HCV, Hepatitis C Virus; HBV, Hepatitis B Virus; HSV, herpes simplex virus; SD, standard
HSV-mediated gene transfer of C3 transferase inhibits Rho to promote axonal regeneration
Keywords: HSV، ویروس هرپس سیمپلکس; C3t, C3 transferase; CSPG, chondroitin sulfate proteoglycans; DREZ, dorsal root entry zone; DRG, dorsal root ganglion; GFP, green fluorescent protein; HCMV IEp, human cytomegalovirus immediate-early promoter; HSV, herpes simplex virus; MAG, myelin associa
Effects of deletion of the early protein 0 gene of pseudorabies virus on the overall viral gene expression
Keywords: HSV، ویروس هرپس سیمپلکس; AST, antisense transcript; E gene, early gene; E/L gene, early/late gene; ep0, early protein 0 gene; ep0Δ, ep0 null mutant PRV; HSV, herpes simplex virus; ICP, infected cell polypeptide; ie180, immediate-early 180 gene; IE gene, immediate-early gene; L ge
Synthesis and antiviral evaluation of C5-substituted-(1,3-diyne)-2′-deoxyuridines
Keywords: HSV، ویروس هرپس سیمپلکس; Diyne scaffold; Nucleoside; Nickel-copper catalyzed C–H activation; Anti-VZV activityVZV-zoster virus, varicella; VV, vaccinia virus; HSV, herpes simplex virus; VSV, vesicular stomatitis virus; DNA, deoxyribonucleic acid; RNA, ribonucleic acid; EC50, comp
A dimerized single-chain variable fragment system for the assessment of neutralizing activity of phage display-selected antibody fragments specific for cytomegalovirus
Keywords: HSV، ویروس هرپس سیمپلکس; AD, antigenic domain; CMV, cytomegalovirus; gB, glycoprotein B; HSV, herpes simplex virus; scFv, single-chain variable fragment(s)Cytomegalovirus; Fc fusion protein; High throughput; Monoclonal antibodies; Phage display; Virus neutralization
New developments and opportunities in oral mucosal drug delivery for local and systemic disease
Keywords: HSV، ویروس هرپس سیمپلکس; GI, Gastro-intestinal; EPR, Enhanced Permeability and Retention; EGFR, Epidermal Growth Factor Receptor; COX-2, Cyclooxygenase 2; HSV, Herpes Simplex Virus; HIV, Human Immunodeficiency VirusOral mucosa; Drug delivery technology; Trans-mucosal; Local drug
Herpes Simplex Virus Hepatitis in Infants: Clinical Outcomes and Correlates of Disease Severity
Keywords: HSV، ویروس هرپس سیمپلکس; ALT, Alanine aminotransaminase; AST, Aspartate aminotransaminase; CNS, Central nervous system; HSV, Herpes simplex virus; ICU, Intensive care unit; INR, International Normalized Ratio; PCR, Polymerase chain reaction
Infection of peripheral blood mononuclear cells with neuropathogenic equine herpesvirus type-1 strain Ab4 reveals intact interferon-α induction and induces suppression of anti-inflammatory interleukin-10 responses in comparison to other viral strains
Keywords: HSV، ویروس هرپس سیمپلکس; CMV, cytomegalovirus; CNS, central nervous system; EHV-1, equine herpesvirus type 1; HSV, herpes simplex virus; MOI, multiplicities of infection; pDC, plasmacytoid dendritic cell; RM ANOVA, repeated-measures analysis of variance; TLR, toll-like receptorCy
Autoimmune bullous diseases: The spectrum of infectious agent antibodies and review of the literature
Keywords: HSV، ویروس هرپس سیمپلکس; PV, pemphigus vulgaris; BP, bullous pemphigoid; ABD, autoimmune bullous diseases; HSV, herpes simplex virus; VZV, varicella zoster virus; EBV, Epstein Barr virus; CMV, cytomegalovirus; HHV 8, human herpes virus 8; HIV, human immunodeficiency virus; HP, He
Molecular Basis for Herpesvirus Entry Mediator Recognition by the Human Immune Inhibitory Receptor CD160 and Its Relationship to the Cosignaling Molecules BTLA and LIGHT
Keywords: HSV، ویروس هرپس سیمپلکس; HVEM, herpesvirus entry mediator; TCR, T cell receptor; NK, natural killer; GPI, glycosylphosphatidylinositol; CRD, cysteine-rich domain; HSV, herpes simplex virus; DC, dendritic cell; SPR, surface plasmon resonance; gD, glycoprotein D; LTα, lymphotoxin-α
Mitochondria and viruses
Keywords: HSV، ویروس هرپس سیمپلکس; ANT, adenine nucleotide translocator; CARD, caspase recruitment domain; HSV, herpes simplex virus; IFN, interferon; MAVS, mitochondrial antiviral signaling protein; MFN, mitofusin; MMP, mitochondrial membrane permeabilization; PTPC, permeability transitio
Of mice and not humans: How reliable are animal models for evaluation of herpes CD8+-T cell-epitopes-based immunotherapeutic vaccine candidates?
Keywords: HSV، ویروس هرپس سیمپلکس; HLA, Human Leukocyte Antigen; HSV, herpes simplex virus; IFN-γ, interferon gamma; Tg, transgenic; TG, trigeminal gangliaTherapeutic vaccine; Animal model; HSV-1; HSV-2; Ocular herpes; Genital herpes; CD8+ T cells
Sulfated modification can enhance the immune-enhancing activity of lycium barbarum polysaccharides
Keywords: HSV، ویروس هرپس سیمپلکس; LBPS, lycium barbarum polysaccharide; sLBPS, sulfated LBPS; HIV, human immunodeficiency virus; HSV, herpes simplex virus; CEF, chicken embryo fibroblast; HI, hemagglutination inhibition; PHA, phytohemagglutinin; ConA, concanavalin A; NDV, Newcastle diseas
Herpes Simplex Virus Testing and Hospital Length of Stay in Neonates and Young Infants
Keywords: HSV، ویروس هرپس سیمپلکس; CFU, Colony-forming unit; CSF, Cerebrospinal fluid; HSV, Herpes simplex virus; IQR, Interquartile range; IRR, Incidence rate ratio; LOS, Length of stay; PCR, Polymerase chain reaction; WBC, White blood cell
Erythema multiforme during anti–tumor necrosis factor treatment for plaque psoriasis
Keywords: HSV، ویروس هرپس سیمپلکس; adalimumab; erythema multiforme; psoriasis; TNF-α; inhibitorDIEM, drug-induced EM; EM, erythema multiforme; FDA, Food and Drug Administration; HAEM, herpes-associated EM; HSV, herpes simplex virus; IL, interleukin; TNF, tumor necrosis factor; VZV, varicel
Nmnat2 delays axon degeneration in superior cervical ganglia dependent on its NAD synthesis activity
Keywords: HSV، ویروس هرپس سیمپلکس; dNmnat, drosophila Nmnat; DRG, dorsol root ganglia; NAD, nicotinamide adenine dinucleotide; HSV, herpes simplex virus; Nmnat, Nicotinamide mononucleotide adenylyl transferase; SCG, superior cervical ganglia; WldS, Wallerian degeneration slowWallerian dege
Reactive nonsexually related acute genital ulcers: Review of cases evaluated at Mayo Clinic
Keywords: HSV، ویروس هرپس سیمپلکس; genital ulcers; Lipschütz ulcer; ulcus vulvae acutumEBV, Epstein-Barr virus; HSV, herpes simplex virus; PCR, polymerase chain reaction; RNSRAGU, reactive nonsexually related acute genital ulcers
Combining prevention of HIV-1, other sexually transmitted infections and unintended pregnancies: Development of dual-protection technologies
Keywords: HSV، ویروس هرپس سیمپلکس; STIs, sexually transmitted infections; HSV, herpes simplex virus; HPV, human papillomavirus; DPT, dual protection system; FC, female condom; LNG, levonorgestrel; CD, cyclodextrin; RTI, reverse transcriptase inhibitor; NtRTI, nucleotide reverse transcripta
Recurrent erythema multiforme: Clinical characteristics, etiologic associations, and treatment in a series of 48 patients at Mayo Clinic, 2000 to 2007
Keywords: HSV، ویروس هرپس سیمپلکس; antiviral agents; erythema multiforme; immunosuppressive agents; recurrent erythema multiformeCR, complete response; EM, erythema multiforme; HSV, herpes simplex virus; IV, intravenous; IVIG, intravenous immunoglobulin; NR, no response; PR, partial respon
Variability and recombination of clinical human cytomegalovirus strains from transplantation recipients
Keywords: HSV، ویروس هرپس سیمپلکس; BAL, bronchoalveolar lavage; D, donor; HCMV, human cytomegalovirus; HSV, herpes simplex virus; LIR-1, leukocyte inhibitory receptor-1; MHC, major histocompatibility complex; NK, natural killer; R, recipient; WB, whole bloodHCMV; Variability; Recombination
Control of α-herpesvirus IE gene expression by HCF-1 coupled chromatin modification activities
Keywords: HSV، ویروس هرپس سیمپلکس; HCF-1, Host Cell Factor-1; HSV, herpes simplex virus; VZV, varicella zoster virus; HMT, histone methyltransferase; HDM, histone demethylase; MLL1, mixed-lineage leukemia; LSD1, lysine-specific demethylase 1; H3K4, histone H3-lysine 4; H3K9, histone H3-lys
A randomized, double-blind, placebo-controlled, phase I study of MEDI-545, an anti–interferon-alfa monoclonal antibody, in subjects with chronic psoriasis
Keywords: HSV، ویروس هرپس سیمپلکس; AE, adverse event; BSA, body surface area; CL, (total body serum) clearance; DLQI, Dermatology Life Quality Index; HSV, herpes simplex virus; IFN, interferon; IV, intravenous; PASI, Psoriasis Area and Severity Index; PGA, Physician Global Assessment; SLE,
Strategies for development of dengue virus inhibitors
Keywords: HSV، ویروس هرپس سیمپلکس; DENV, dengue virus; WNV, West Nile virus; YFV, yellow fever virus; HCV, hepatitis C virus; HTS, high-throughput screening; RdRp, RNA-dependent RNA polymerase; HIV, human immunodeficiency virus; HSV, herpes simplex virus; UTR, untranslated region; SAR, str
Echovirus type 9 is an important cause of viral encephalitis among infants and young children in Kuwait
Keywords: HSV، ویروس هرپس سیمپلکس; CNS, central nervous system; CSF, cerebrospinal fluid; CT, computed tomography; E, Echovirus; EV, Enterovirus; HSV, herpes simplex virus; MRI, magnetic resonance imagingEncephalitis; Enteroviruses; Echovirus type 9; Infants; Kuwait
Prevalence of serum antibodies to TORCH among women before pregnancy or in the early period of pregnancy in Beijing
Keywords: HSV، ویروس هرپس سیمپلکس; TOX, Toxoplasma gondii; RV, Rubella virus; CMV, Cytomegalovirus; HSV, Herpes simplex virus; TORCH, Acronym for TOX, RV, CMV and HSVTORCH; CLIA; Methodology; Infective rate