Keywords: هیدروتیدین; DCFDA); 2â²,7â²-dichlorofluorescin diacetate; FCCP); carbonyl cyanide-p-trifluoromethoxyphenylhydrazone; CoQ); Coenzyme Q; CI); Complex I; ETC); electron transport chain; H2O2); hydrogen peroxide; HE); hydroethidine; LC); liquid chromatography; MS); mas
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Keywords: هیدروتیدین; Nanomaterials; Chitosan; Nanocytotoxicity; Aggregation; Hematopoietic stem cells; Lineage-committed progenitors; CSNPs; Chitosan nanoparticles; DHE; dihydroethidium; FITC; fluorescein isothiocyanate; H2O2; hydrogen peroxide; HE; hydroethidine; HSPCs; hema
Keywords: هیدروتیدین; HE; hydroethidine; oxHE; oxidized hydroethidine; 2-OH-E+; 2-hydroxyethidium; E+; ethidium cation; HPLC; high-performance liquid chromatography; FL; fluorescence; FC; flow cytometry; Rh123; rhodamine 123; AnV; Annexin V; DPI; diphenyleneiodonium; H2DCFDA;
Antioxidant and pro-oxidant mechanisms of (+) catechin in microsomal CYP2E1-dependent oxidative stress
Keywords: هیدروتیدین; Antioxidant; Catechin; CYP2E1; Microsomes; Oxidative stress; Reactive oxygen species; b5; Cytochrome b5; CPâ; 3-carboxy-proxyl radical; CPH; 1-hydroxy-3-carboxy-2,2,5,5-tetramethylpyrrolidine; CPR; NADPH cytochrome P450 reductase; CYP2E1; Cytochrome P45
Zn2+-induced disruption of neuronal mitochondrial function: Synergism with Ca2+, critical dependence upon cytosolic Zn2+ buffering, and contributions to neuronal injury
Keywords: هیدروتیدین; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; Ca-AMPA; Ca2+ permeable AMPA channels; FCCP; carbonyl cyanide-p-trifluoromethoxyphenylhydrazone; DTDP; 2,2â²-dithiodipyridine; HEt; hydroethidine; MT; metallothionein; NMDA; N-methyl-D-aspartat
Flow cytometric HyPer-based assay for hydrogen peroxide
Keywords: هیدروتیدین; MSCs; mesenchymal stem cells; ROS; reactive oxygen species; H2DCFDA; 2', 7'-dichlorodihydrofluorescein diacetate; DTT; dithiothreitol; NAC; N-acetyl-L-cysteine; CV; coefficient of variation; HE; hydroethidine; BCECF AM; 2',7'-bis-(2-carboxyethyl)-5-(and-6
Extracellular acidification induces ROS- and mPTP-mediated death in HEK293 cells
Keywords: هیدروتیدین; ÎÏ; mitochondrial membrane potential; AA; antimycin A; CI; complex I or NADH:Ubiquinone oxidoreductase; CIII; complex III or Ubiquinol-cytochrome c oxidoreductase; CsA; cyclosporin A; ETC; electron transport chain; Fer-1; ferrostatin-1; HEt; hydroethidi
Different roles of Nrf2 and NFKB in the antioxidant imbalance produced by esculetin or quercetin on NB4 leukemia cells
Keywords: هیدروتیدین; Antioxidants; Apoptosis; Esculetin; Hydrogen peroxide; Reactive oxygen species; Tert-butylhydroperoxide; APL; Acute promyelocytic leukemia; Annexin V-FITC; fluorescein isothiocyanate coupled to annexin V; BSO; buthionine-[SR]-sulfoximine; DMSO; dimethyl s
Luteolin attenuates neutrophilic oxidative stress and inflammatory arthritis by inhibiting Raf1 activity
Keywords: هیدروتیدین; CFA; complete Freund's adjuvant; CB; cytochalasin B; fMLF; N-formyl-Met-Leu-Phe; HE; hydroethidine; LPS; lipopolysaccharide; LTB4; leukotriene B4; MMK-1; Leu-Glu-Ser-Ile-Phe-Arg-Ser-Leu-Leu-Phe-Arg-Val-Met; MAPK; mitogen-activated protein kinase; MPO; m
Dipeptide HCH6-1 inhibits neutrophil activation and protects against acute lung injury by blocking FPR1
Keywords: هیدروتیدین; [Ca2+]i; intracellular calcium concentration; ALI; acute lung injury; CB; cytochalasin B; CsH; cyclosporine H; FBS; fetal bovine serum; FNLFNYK; N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys-fluorescein; FPR1; formyl peptide receptor 1; HE; Hydroethidine; H89; N-[2-(p
Regulatory role of NADPH oxidase 2 in the polarization dynamics and neurotoxicity of microglia/macrophages after traumatic brain injury
Keywords: هیدروتیدین; TBI; traumatic brain injury; ROS; reactive oxygen species; NF-κB; Nuclear factor-kappa B; APO; apocynin; VE; vehicle; LPS; lipopolysaccharides; IFN-γ; interferon-γ, IL, interleukin; TNF; tumor necrosis factor; HEt; hydroethidine; ROI; regions of intere
Early alterations on photosynthesis-related parameters in Chlamydomonas reinhardtii cells exposed to atrazine: A multiple approach study
Keywords: هیدروتیدین; a.u.; arbitrary units; CCM; carbon concentrating mechanism; Ci; inorganic carbon dioxide; CHAPS; 3-[(3-Cholamidopropyl) dimethylammonio]-1-propanesulfonate hydrate; EB; etidium bromide; FCM; flow cytometry; FDR; false discovery rate; FS; forward scatter l
Detailed protocol to assess in vivo and ex vivo myeloperoxidase activity in mouse models of vascular inflammation and disease using hydroethidine
Keywords: هیدروتیدین; Apoeâ/â; apolipoprotein E gene knockout; CE; collision energy; 2-Cl-E+; 2-chloroethidium; 2-Cl-E+- d5; deuterated 2-chloroethidium; 3-Cl-Tyr; 3-chlorotyrosine; DTPA; diethylene triamine pentaacetic acid; E+-E+; diethidium; E+; ethidium; HOCl; hypochlo
Use of spin traps to detect superoxide production in living cells by electron paramagnetic resonance (EPR) spectroscopy
Keywords: هیدروتیدین; 2-OH-E+; 2-hydroxyethidium; AMPO; 5-carbamoyl-5-methyl-1-pyrroline N-oxide; BMPO; 5-tert-butoxycarbonyl-5-methyl-1-pyrroline N-oxide; CD; cyclodextrin; CD-DEPMPO; 6-monodeoxy-6-mono-4-[(5-diethoxyphosphoryl-5-methyl-1-pyrroline-N-oxide)-ethylenecarbamoyl-
Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis
Keywords: هیدروتیدین; ALS; amyotrophic lateral sclerosis; BBB; blood brain barrier; 2-Cl-E+; 2-chloroethidium; CNS; central nervous system; DMSO; Dimethylsulfoxide; DPI; diphenyleneiodonium; DMEM; Dulbecco's modified Eagle Medium; DNA; deoxyribonucleic acid; DUOX; dual oxidase
Uncoupling protein-2 attenuates palmitoleate protection against the cytotoxic production of mitochondrial reactive oxygen species in INS-1E insulinoma cells
Keywords: هیدروتیدین; Pancreatic beta cells; Glucolipotoxicity; Cytoprotection; Mitochondrial dysfunction; Uncoupling protein-2 (UCP2); Reactive oxygen species; INS-1E insulinoma cells; Non-esterified fatty acids; Obesity; Type 2 diabetes; BSA; bovine serum albumin; DAPI; 4â²
Low micromolar concentrations of the superoxide probe MitoSOX uncouple neural mitochondria and inhibit complex IV
Keywords: هیدروتیدین; aCSF; artificial cerebrospinal fluid; DIV; days in vitro; DNP; 2,4-dinitrophenol; FCCP; carbonyl cyanide 4-(trifluoromethyoxy) phenylhydrazone; HIF-1; hypoxia-inducible factor-1; OCR; oxygen consumption rate; ROS; reactive oxygen species; TMPD; N,N,N',N
HPLC-based monitoring of products formed from hydroethidine-based fluorogenic probes - The ultimate approach for intra- and extracellular superoxide detection
Keywords: هیدروتیدین; 2-OH-E+; 2-hydroxyethidium; E+; ethidium; HE; hydroethidine; HPr+; hydropropidine; MitoSOXTM Red or Mito-HE; HE conjugated to TPP+ group; TPP+; triphenylphosphonium cation; SOD; superoxide dismutase; Superoxide radical anion; Hydroethidine; MitoSOX; Hydro
Phosphorylation of flotillin-1 by mitochondrial c-Src is required to prevent the production of reactive oxygen species
Keywords: هیدروتیدین; Cx; respiratory complex; DDM; n-dodecyl-β-D-maltoside; GST; glutathione S-transferase; H2DCFDA; 2â², 7â²-dichlorofluorescin diacetate; HE; hydroethidine; mAb; monoclonal antibody; KD; kinase dead; MTS; mitochondria-targeting sequence; NDUFV2; NADH dehy
On the use of fluorescence lifetime imaging and dihydroethidium to detect superoxide in intact animals and ex vivo tissues: A reassessment
Keywords: هیدروتیدین; 2-OH-E+; 2-hydroxyethidium; DE; deuteroethidine; DHE; dihydroethidium; dtpa; diethylenetriaminepentaacetate; E+; ethidium; HE; hydroethidine; HX; hypoxanthine; X; xanthine; XO; xanthine oxidase; HRP; horseradish peroxidase; TFA; trifluoroacetic acid;
A novel immunomodulatory effect of ugonin U in human neutrophils via stimulation of phospholipase C
Keywords: هیدروتیدین; [Ca2+]i; intracellular calcium concentration; EB; ethidium bromide; ER; endoplasmic reticulum; fMLF; N-formylmethionyl-leucyl-phenylalanine; FNLFNYK; N-formyl-Nle-Leu-Phe-Nle-Tyr-Lys-fluorescein; FPR1; formyl peptide receptor 1; HE; hydroethidine; IP3; in
Detection of superoxide anion and hydrogen peroxide production by cellular NADPH oxidases
Keywords: هیدروتیدین; CGD; chronic granulomatous disease; cpYFP; circularly permutated form of the yellow fluorescent protein; DCFH2; dihydrofluorescein; DH2R; dihydrorhodamine; DUOX; dual oxidase (1 or 2); DUOXA; dual oxidase maturation factor (1 or 2); fMLF; formyl methionyl
Synthesis of a new class of pyrrolo[3,4-h]quinazolines with antimitotic activity
Keywords: هیدروتیدین; Pyrrolo[3,4-h]quinazolines; Antiproliferative activity; Antimitotic activity; Tubulin polymerization; Vascular disrupting activity; AO; acridine orange; EGFR; Epidermal Growth Factor Receptor; FITC; fluorescein isothiocyanate; H2DCFDA; 2â²,7â²-dichlorod
S-linolenoyl glutathione intake extends life-span and stress resistance via Sir-2.1 upregulation in Caenorhabditis elegans
Keywords: هیدروتیدین; AD; Alzheimer disease; Aβ; amyloid-β peptide; BCNU; 1,3-bis-(2-chloroethyl)-1-nitrosourea; GSH ethyl ester; C-terminal glycine of GSH; DMSO; dimethyl sulfoxide; PBS; phosphate-buffered saline; EX-527; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxami
Mitochondrial genome depletion in human liver cells abolishes bile acid-induced apoptosis: Role of the Akt/mTOR survival pathway and Bcl-2 family proteins
Keywords: هیدروتیدین; ABC; ATP-binding cassette; Akt; protein kinase B; BCRP; Breast cancer resistance protein; BSEP; Bile salt export pump; DCA; Deoxycholic acid; DCFH-DA; 2â²,7â²-dichlorofluorescein diacetate; ERK; Extracellular regulated kinase; EtBr; Ethidium bromide; GC
The walking dead: Is hydroethidine a suitable viability dye for intra-erythrocytic Plasmodium falciparum?
Keywords: هیدروتیدین; Plasmodium falciparum; Hydroethidine; Thiazole orange; Viability;
A simplified hydroethidine method for fast and accurate detection of superoxide production in isolated mitochondria
Keywords: هیدروتیدین; Superoxide; Hydroethidine; C. elegans; Isolated mitochondria
Superoxide plays critical roles in electrotaxis of fibrosarcoma cells via activation of ERK and reorganization of the cytoskeleton
Keywords: هیدروتیدین; DCEF; direct-current electrical field; DCFH-DA; dichlorofluorescein diacetate; DPI; diphenylene iodonium; HE; hydroethidine; MAPK; mitogen-activated protein kinase; mCAT; mitochondrial catalase; MnSOD; mitochondrial superoxide dismutase; NADPH; nicotinami
Effects of reactive oxygen species on sperm function
Keywords: هیدروتیدین; Hydroethidine; C11-BODIPY581/591; Lipid peroxidation; Reactive oxygen species; Flow cytometry; Motility;
Androcoll-E large selects a subset of live stallion spermatozoa capable of producing ROS
Keywords: هیدروتیدین; SLC; single layer centrifugation; SL; single layer; UC; uncentrifuged; BWW; Biggers-Whitten-Whittingham; ROS; reactive oxygen species; mOsm; milliosmolar; MMP; mitochondrial membrane potential; JC-1; 5,5â²,6,6â²-tetrachloro-1,1â²,3,3â² tetraethylb
Detection of reactive oxygen species derived from the family of NOX NADPH oxidases
Keywords: هیدروتیدین; AGT; alkylguanine-DNA alkyltransferase; CGD; chronic granulomatous disease; cpYFP; circularly permuted yellow fluorescent protein; DCFH; 2â²,7â²-dichlorofluorescein; DPI; diphenyleneiodonium; DUOX; Dual oxidase; ER; endoplasmic reticulum; E+; ethidium;
Hydroethidine as a probe for measuring superoxide formation rates during air oxidation of myricetin and quercetin
Keywords: هیدروتیدین; Pro-oxidant; Superoxide; Myricetin; Hydroethidine; Fluorescent probe;
Stachybotrys microspora triprenyl phenol-7, a novel fibrinolytic agent, suppresses superoxide production, matrix metalloproteinase-9 expression, and thereby attenuates ischemia/reperfusion injury in rat brain
Keywords: هیدروتیدین; SMTP; Stachybotrys microspora triprenyl phenol; tFCI; transient focal cerebral ischemia; MMP-9; matrix metalloproteinase-9; ROS; reactive oxygen species; tPA; tissue-type plasminogen activator; MCA; middle cerebral artery; ICA; internal carotid artery; EC
Extracellular ATP induces spikes in cytosolic free Ca2+ but not in NADPH oxidase activity in neutrophils
Keywords: هیدروتیدین; [Ca2+]cyt; cytosolic Ca2+ concentration; DAG; diacyl glycerol; fMLP; N-Formyl-l-methionyl-l-leucyl-l-phenylalanine; HE; hydroethidine; HRP; horseradish peroxidase; PKC; protein kinase C; PB; peripheral blood; PMA; phorbol-12-myristate-13-acetate; ATP; Cal
Spectrofluorometry assays for oxidative stress and apoptosis, with cell viability on the same microplates: A multiparametric analysis and quality control
Keywords: هیدروتیدین; Neutral red; Hydroethidine; H2DCF-DA; YO-PRO®-1; Simultaneous staining; Microplate fluorescence spectrophotometry; Quality control; Multiparametric analysis
Uncoupling protein-2 attenuates glucose-stimulated insulin secretion in INS-1E insulinoma cells by lowering mitochondrial reactive oxygen species
Keywords: هیدروتیدین; âÏ; mitochondrial membrane potential; DAPI; 4â²,6-diamidino-2-phenylindole; DHE; hydroethidine; FCS; fetal calf serum; FCCP; carbonyl cyanide p-trifluoromethoxyphenylhydrazone; GSIS; glucose-stimulated insulin secretion; KRH; Hepes-buffered Krebs-Ri
PPARγ stabilizes HO-1 mRNA in monocytes/macrophages which affects IFN-β expression
Keywords: هیدروتیدین; 15d-PGJ2; 15-deoxy-Î12,14-prostaglandin J2; CRE; causes recombination; CO; carbon monoxide; CHX; cycloheximide; d/n; dominant negative; DPI; diphenyliodonium; HE; hydroethidine; HO-1; heme oxygenase-1; LPS; lipopolysaccharide; LysM; lysozyme M; mac; macr
Antioxidant signaling via Nrf2 counteracts lipopolysaccharide-mediated inflammatory responses in foam cell macrophages
Keywords: هیدروتیدین; ARE; antioxidant response element; bZIP; basic-leucine zipper; C/EBP; CCAAT/enhancer binding protein; CORM2; tricarbonyldichlororuthenium(II) dimer; COX-2; cyclooxygenase-2; DMNQ; 2,3-dimethoxy-1-naphthoquinone; DMSO; dimethyl sulfoxide; DPI; diphenyliodo
Methodology and application of flow cytometry for investigation of human malaria parasites
Keywords: هیدروتیدین; AO; acridine orange; DBP; Duffy binding protein; EBA; erythrocyte binding antigen; ETBR; ethidium bromide; GIA; growth inhibitory assay; HO258; Hoechst 33258; HO342; Hoechst 33342; HE; hydroethidine; HX; hypoxanthine; IC50; 50% inhibitory concentration; I
ES936 stimulates DNA synthesis in HeLa cells independently on NAD(P)H:quinone oxidoreductase 1 inhibition, through a mechanism involving p38 MAPK
Keywords: هیدروتیدین; DCFH-DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DZQ; 2,5 bis-[1-aziridyl]-1,4 benzoquinone; ES936; 5-methoxy-1,2-dimethyl-3-[(4-nitrophenol)methyl]-indole-4,7-dione; FCS; fetal calf serum; Het; hydroethidine; NQO1, NAD(P)H; quinone oxidoreductase
Detection and manipulation of mitochondrial reactive oxygen species in mammalian cells
Keywords: هیدروتیدین; α-KGDH; α-ketoglutarate dehydrogenase; MIM; mitochondrial inner membrane; MOM; mitochondrial outer membrane; RET; reverse electron transfer; ROI; region of interest; t1/2; half-life; TPP+; triphenylphosphonium; Hydroethidine; Redox-sensitive GFP; cpYFP;
Hydroethidine- and MitoSOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: Another inconvenient truth
Keywords: هیدروتیدین; Hydroethidine; Superoxide radical anion; Fluorescent probes; HPLC; Free radicals; Reactive oxygen species
Involvement of NADPH oxidase and protein kinase C in endothelin-1-induced superoxide production in retinal microvessels
Keywords: هیدروتیدین; endothelin; retinal microvessel; pericyte; hydroethidine; superoxide anion
HPLC study of oxidation products of hydroethidine in chemical and biological systems: ramifications in superoxide measurements
Keywords: هیدروتیدین; Hydroethidine; Mito-hydroethidine; MitoSOX; HPLC; Superoxide; Fluorescence; Ethidium; Diethidium; 2-Hydroxyethidium; Free radicals
Mitochondrial function and reactive oxygen species action in relation to boar motility
Keywords: هیدروتیدین; Hydroethidine; C11-BODIPY581/591; Lipid peroxidation; Reactive oxygen species; Flow cytometry
Salvicine triggers DNA double-strand breaks and apoptosis by GSH-depletion-driven H2O2 generation and topoisomerase II inhibition
Keywords: هیدروتیدین; ATZ; 3-amino-1,2,4-triazole; BSO; dl-buthionine-[S,R]-sulfoximine; CAT; catalase; DCF; 2,7-dichlorofluorescein; DCFH2-DA; 2,7-dichlorodihydrofluorescein diacetate; DPI; diphenyleneiodonium chloride; DSB; double-strand break; GSH; glutathione; HE; hydroeth
Induction of γ-globin mRNA, erythroid differentiation and apoptosis in UVA-irradiated human erythroid cells in the presence of furocumarin derivatives
Keywords: هیدروتیدین; 5-MOP; 5-methoxypsoralen; 8-MOP; 8-methoxypsoralen; ÎÏmt; mitochondrial potential; ANG; angelicin; BFUe; erythroid burst forming units; CFUe; erythroid colony forming units; EPO; erythropoietin; HBSS; Hank's balanced salt solution; HE; hydroethidine; IC
Systematic study on ROS production induced by oleic, linoleic, and γ-linolenic acids in human and rat neutrophils
Keywords: هیدروتیدین; Fatty acids; ROS; Luminol; Lucigenin; Cytochrome c; Hydroethidine; Neutrophils; Free radicals
Pulse radiolysis and steady-state analyses of the reaction between hydroethidine and superoxide and other oxidants
Keywords: هیدروتیدین; Hydroethidine; 2-Hydroxyethidium; Ethidium; Superoxide; Fenton’s reaction; HPLC; Pulse radiolysis; One-electron oxidation
Sevoflurane-induced oxidative stress and cellular injury in human peripheral polymorphonuclear neutrophils
Keywords: هیدروتیدین; DCF; dichlorofluorescein; GSH; glutathione; ROS; reactive oxygen species; DCFH-DA; 2â²,7â²-dichlorodihydrofluorescein-diacetate; HE; hydroethidine; DAF-2; 4,5-diaminofluorescein; CMF-DA; chloromethylflourescein diacetate; PI; propidium iodide; NO; nitri