Keywords: فاکتور القای هیپوکسی -1; DR; diabetic retinopathy; EPC; endothelial progenitor cell; DME; diabetic macular edema; EC; endothelial cells; VTDR; vision-threatening diabetic retinopathy; PDR; proliferative diabetic retinopathy; NVI; neovascularization in the iris; IOP; intraocular p
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Keywords: فاکتور القای هیپوکسی -1; ER; estrogen receptor; PR; progesterone receptor; HER2; human epidermal receptor 2; NF-κB; nuclear factor kappa-light-chain-enhancer of activated B cells; STAT; signal transducer and activator of transcription; CHM; Chinese herbal medicine; EMT; epitheli
Keywords: فاکتور القای هیپوکسی -1; Endosulfan; RNA-seq; Cytotoxicity; Hypoxia-inducible factor-1; Extracellular matrix-receptor interaction;
Keywords: فاکتور القای هیپوکسی -1; BRS; baroreflex sensitivity; CO2et; end-tidal carbon dioxide pressure; DLCO; diffusing capacity of the lung for carbon monoxide; FEV1; forced expiratory volume (at the end of the first second of forced expiration); FVC; forced vital capacity; HIF-1; hypox
Keywords: فاکتور القای هیپوکسی -1; AFB1; aflatoxin B1; CSC; cancer stem cell; ECM; extracellular matrix; EMT; epithelial-mesenchymal transition; ERK; extracellular signal-regulated kinase; GH; growth hormone; HCC; hepatocellular carcinoma; HIF-1; hypoxia-inducible factor-1; HK; hexokinase;
Keywords: فاکتور القای هیپوکسی -1; Diabetic ischemic limb; Glutamine; Endothelial progenitor cells; Hypoxia-inducible factor-1; CD31;
Keywords: فاکتور القای هیپوکسی -1; AGE; advanced glycation end products; BM-EPCs; bone marrow-derived endothelial progenitor cells; CAD; coronary artery disease; CV; cardiovascular; DM; diabetes mellitus; EPCs; endothelial progenitor cells; G-CSF; granulocyte colony-stimulating factor; HIF
Keywords: فاکتور القای هیپوکسی -1; ACL; ATP citrate lyase; Akt; Protein kinase B; ASCT2; Alanine, serine, cysteine-preferring transporter 2; ASS; Argininosuccinate synthetase; BMI; Body mass index; CAF; Cancer-associated fibroblasts; ER; Estrogen receptor; FASN; Fatty acid synthase; GPC; G
Keywords: فاکتور القای هیپوکسی -1; hypoxia-inducible factor-1; obliterative bronchiolitis; lung transplantation; Von Hippel-Lindau protein; allograft rejection;
Keywords: فاکتور القای هیپوکسی -1; BCVA; best-corrected visual acuity; BRVO; branch retinal vein occlusion; CRVO; central retinal vein occlusion; DME; diabetic macular edema; HARBOR; Phase III, Double-Masked, Multicenter, Randomized, Active Treatment-Controlled Study of the Efficacy and Sa
Keywords: فاکتور القای هیپوکسی -1; HIF-1; Hypoxia-inducible factor-1; CA-IX; Carbonic anhydrase-IX; VEGF; Vascular endothelial growth factor; HDVC; High dose vitamin C; PHH3; Phospho-histone H3; LL/2; Lewis lung carcinoma; FFPE; Formalin fixed paraffin embedded; HPLC; high performance liqu
Keywords: فاکتور القای هیپوکسی -1; 2-ME; 2-methoxyestradiol; CAIX; carbonic anhydrase IX; CSC; cancer stem cell; Dtx; docetaxel; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; FIH-1; factor inhibiting HIF-1; GSCs; glioma stem cells; HIF-1; hypoxia-inducible factor-1;
Keywords: فاکتور القای هیپوکسی -1; Copper; Cardiac hypertrophy; CCO; Angiogenesis; VEGFRs; HIF-1; ANG-1; angiopoietin-1; ANG-2; angiopoietin-2; ANP; atrial natriuretic peptide; ATOX1; antioxidant 1; ATP; adenosine triphosphate; BNP; B-type natriuretic peptide; BNIP3; BCL2/adenovirus E1B 19
Keywords: فاکتور القای هیپوکسی -1; HIF-1; hypoxia-inducible factor-1; VHL; von Hippel-Lindau; PHD; prolyl hydroxylase; HTS; high-throughput screening; NBS; N-bromosuccinimide; MNBA; 2-methyl-6-nitrobenzoic anhydride; DIBAL; diisobutylaluminum hydride; VEGF-PLAP; vascular endothelial grow
Keywords: فاکتور القای هیپوکسی -1; Aβ; amyloid-β peptides; APAF-1; apoptotic protease-activating factor-1; E2; 17β-estradiol; ER; estrogen receptor; ERβ; estrogen receptor β; ERE; estrogen responsive elements; HIF-1; hypoxia-inducible factor-1; mPTP; mitochondria permeability transiti
Keywords: فاکتور القای هیپوکسی -1; HRE; hypoxia-responsive element; HIF-1; hypoxia-inducible factor-1; MTT; 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide; siRNA; small interfering RNA; AMPK; 5â²-adenosine monophosphate-activated protein kinase; PBS; phosphate buffered sal
Keywords: فاکتور القای هیپوکسی -1; AC; adenylyl cyclase; BAT; brown adipose tissue; BMP; bone morphogenetic protein; BST; bed nucleus of the stria terminalis; CB1R; cannabinoid receptor type 1; CNS; central nervous system; CREB; cAMP-response element binding protein; DRN; dorsal raphe nucl
Keywords: فاکتور القای هیپوکسی -1; Bcl-2; B cell lymphoma 2; Bcl-xL; B cell lymphoma-extra large; ARE; antioxidant-response element; Cul3; cullin 3; Cyt c; cytochrome c; Drp1; dynamin-related protein 1; ERK; extracellular signal-regulated kinase; GSH; glutathione; GST; glutathione S-tran
Keywords: فاکتور القای هیپوکسی -1; Hypoxia-inducible factor-1; Regulated in development and DNA damage response-1; Mammalian target of rapamycin; Hypoxia; Trophoblast; BeWo cells; Regulation
Ferritin heavy chain controls the HIF-driven hypoxic response by activating the asparaginyl hydroxylase FIH
Keywords: فاکتور القای هیپوکسی -1; Ferritin heavy chain; Hypoxia-inducible factor-1; Factor inhibiting HIF;
The dichotomous role of H2S in cancer cell biology? Déjà vu all over again
Keywords: فاکتور القای هیپوکسی -1; 1400 W; N-[[3-(aminomethyl)phenyl]methyl]-ethanimidamide; 3-MP; 3-Mercaptopyruvate; 3-MST; 3-Mercaptopyruvate sulfurtransferase; ADT-OH; 5-(4-hydroxyphenyl)-3H-1, 2-dithiole-3-thione; AG; Aminoguanidine; AOAA; Aminooxyacetic acid; CAT; Cysteine aminotra
Cobalt-containing bioactive glasses reduce human mesenchymal stem cell chondrogenic differentiation despite HIF-1α stabilisation
Keywords: فاکتور القای هیپوکسی -1; Bioactive glasses; Cobalt; Mesenchymal stem cells; Chondrogenesis; Hypoxia-inducible factor-1;
Genipin inhibits the invasion and migration of colon cancer cells by the suppression of HIF-1α accumulation and VEGF expression
Keywords: فاکتور القای هیپوکسی -1; Genipin; Hypoxia-inducible factor-1; Vascular endothelial growth factor; Invasion; Akt; ERK;
Distinct hypoxic regulation of preadipocyte factor-1 (Pref-1) in preadipocytes and mature adipocytes
Keywords: فاکتور القای هیپوکسی -1; ARNT; aryl hydrocarbon receptor nuclear translocator; C/EBP; CCAAT-enhancer-binding proteins; CM; conditioned media; Epi; epididymal adipose tissue; HFD; high fat diet; HIF-1; hypoxia-inducible factor-1; HRE; hypoxia responsive elements; MDI; 3-isobutyl-1
PI3K pathway in prostate cancer: All resistant roads lead to PI3K
Keywords: فاکتور القای هیپوکسی -1; CRPC; castration-resistant prostate cancer; ADT; androgen deprivation therapy; PI3K; phosphoinositide 3-kinase; AR; androgen receptor; PTEN; phosphatase and tensin homologue deleted on chromosome 10; INPP4B; inositol polyphosphate 4-phosphatase type II; P
Unraveling the role of hypoxia-inducible factor (HIF)-1α and HIF-2α in the adaption process of human microvascular endothelial cells (HMEC-1) to hypoxia: Redundant HIF-dependent regulation of macrophage migration inhibitory factor
Keywords: فاکتور القای هیپوکسی -1; Hypoxia; Angiogenesis; Bioenergetic adaptation; Hypoxia-inducible factor-1; Hypoxia-inducible factor-2; Macrophage migration inhibitory factor;
Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1α via the mTOR/p70S6K/4E-BP1 and MAPK pathways
Keywords: فاکتور القای هیپوکسی -1; HIF-1; hypoxia-inducible factor-1; PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; MAPK; mitogen-activated protein kinase; VEGF; vascular endothelial growth factor; EPO; erythropoietin; Topo-I; topoisomerase-I; eIF4E; eukaryotic
Modulation of signaling mechanisms in the heart by thioredoxin 1
Keywords: فاکتور القای هیپوکسی -1; Akt; protein kinase B; AMPK; Adenosine Monophosphate-activated Protein Kinase; Ang-II; Angiotensin-II; AP1; Activator protein 1 (AP-1); ASK1; Apoptosis Signal-regulating kinase; Atg4; Autophagy related-4; ATP; Adenosine Triphosphate; CDDP; cis-diammine-di
Redox regulation of cardiovascular inflammation - Immunomodulatory function of mitochondrial and Nox-derived reactive oxygen and nitrogen species
Keywords: فاکتور القای هیپوکسی -1; AP-1; activator protein-1; AT1R; angiotensin II receptor type 1; AT-II; angiotensin II; bFGF; basic fibroblast growth factor; CCR; C-C chemokine receptor; cGMP; cyclic guanosine monophosphate; DC; dendritic cell; eNOS; endothelial nitric oxide synthase;
Research reportInhibition of AMP-activated protein kinase alleviates focal cerebral ischemia injury in mice: Interference with mTOR and autophagy
Keywords: فاکتور القای هیپوکسی -1; AMPK; AMP-activated protein kinase; Atg; autophagy related gene; DAP1; death associated protein 1; 4EBP1; eukaryotic initiation factor 4E binding protein 1; FGF; fibroblast growth factor; HIF-1; hypoxia-inducible factor-1; FIP; FAK family kinase-interacti
New insight into the role of metabolic reprogramming in melanoma cells harboring BRAF mutations
Keywords: فاکتور القای هیپوکسی -1; ATP; adenosine triphosphate; BRAF; serine/threonine-protein kinase B-Raf; cAMP; cyclic adenosine monophosphate; CDK4; cyclin-dependent kinases 4; CREB; cAMP response element binding protein; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxi
MnTE-2-PyP modulates thiol oxidation in a hydrogen peroxide-mediated manner in a human prostate cancer cell
Keywords: فاکتور القای هیپوکسی -1; PAI-1; plasminogen activator inhibitor-1; ROS; reactive oxygen species; HRE; hypoxia-response element; SOD1; superoxide dismutase 1; HIF-1; hypoxia-inducible factor-1; CREB; cAMP response element-binding protein; ChIP; chromatin immunoprecipitation; ARNT;
Regulation of angiogenin expression and epithelial-mesenchymal transition by HIF-1α signaling in hypoxic retinal pigment epithelial cells
Keywords: فاکتور القای هیپوکسی -1; Angiogenin; RNase 4; Epithelial-mesenchymal transition; Hypoxia-inducible factor-1; Choroidal neovascularization;
Novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitor: Synthesis, anti-invasive and anti-angiogenic properties
Keywords: فاکتور القای هیپوکسی -1; Hypoxia-inducible factor-1; Chalcone; Cancer; Invasion; Angiogenesis
PI3K/Akt signaling in osteosarcoma
Keywords: فاکتور القای هیپوکسی -1; OS; osteosarcoma; PI3K; phosphatidylinositol 3-kinase; PTEN; phosphatase and tensin homolog; mTOR; mammalian target of rapamycin; RTKs; receptor tyrosine kinases; PDGFR; platelet-derived growth factor receptor; IGF1R; insulin-like growth factor 1 receptor
Molecular pathogenesis of retinal and choroidal vascular diseases
Keywords: فاکتور القای هیپوکسی -1; Angiogenesis; Age-related macular degeneration; Diabetic retinopathy; Hypoxia-inducible factor-1; Vascular endothelial growth factor; Vascular endothelial-protein tyrosine phosphatase; TIE2; Angiopoietins; Platelet-derived growth factor;
The antioxidant function of sestrins is mediated by promotion of autophagic degradation of Keap1 and Nrf2 activation and by inhibition of mTORC1
Keywords: فاکتور القای هیپوکسی -1; Sesn; sestrin; ROS; reactive oxygen species; Prx; peroxiredoxin; Srx; sulfiredoxin; ERK; extracellular signal-regulated kinase; Nrf2; nuclear factor erythroid 2-related factor 2; Keap1; Kelch-like ECH-associated protein 1; mTORC1; mechanistic target of ra
Low micromolar concentrations of the superoxide probe MitoSOX uncouple neural mitochondria and inhibit complex IV
Keywords: فاکتور القای هیپوکسی -1; aCSF; artificial cerebrospinal fluid; DIV; days in vitro; DNP; 2,4-dinitrophenol; FCCP; carbonyl cyanide 4-(trifluoromethyoxy) phenylhydrazone; HIF-1; hypoxia-inducible factor-1; OCR; oxygen consumption rate; ROS; reactive oxygen species; TMPD; N,N,N',N
Overexpression of ERβ is sufficient to inhibit hypoxia-inducible factor-1 transactivation
Keywords: فاکتور القای هیپوکسی -1; Estrogen receptor beta; Hypoxia; Hypoxia-inducible factor-1;
A new method to assay hypoxia-inducible factor-1 based on small molecule binding DNA
Keywords: فاکتور القای هیپوکسی -1; Hypoxia-inducible factor-1; Echinomycin; Biosensor; Electroanalysis; Preeclampsia
The effects of hypoxic preconditioning on white matter damage following hypoxic-ischaemic injury in the neonatal rat brain
Keywords: فاکتور القای هیپوکسی -1; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid; BSA; bovine serum albumin; CC; corpus callosum; CPu; caudate putamen; Cx; cortex; DAB; diaminobenzidine; HI; hypoxia-ischaemia; HP; hypoxic preconditioning; HIF-1; hypoxia-inducible factor-1; H
Hypoxia induces peroxisome proliferator-activated receptor γ expression via HIF-1-dependent mechanisms in HepG2 cell line
Keywords: فاکتور القای هیپوکسی -1; Hypoxia; Hypoxia-inducible factor-1; Peroxisome proliferator-activated receptor γ; HepG2 cell line; Human hepatocellular carcinoma;
Intracellular ascorbate enhances hypoxia-inducible factor (HIF)-hydroxylase activity and preferentially suppresses the HIF-1 transcriptional response
Keywords: فاکتور القای هیپوکسی -1; Ascorbate; Hypoxia-inducible factor-1; Cancer; Hydroxylase; Bcl-2/adenovirus E1B 19-kDa interacting protein 3; BNIP3; Vascular endothelial cell growth factor; Free radicals;
Mitochondrial EF4 links respiratory dysfunction and cytoplasmic translation in Caenorhabditis elegans
Keywords: فاکتور القای هیپوکسی -1; C. elegans; Caenorhabditis elegans; WT; wild-type; EF4; elongation factor 4; mtEF4; mitochondrial EF4; mtDNA; mitochondrial DNA; BP; base pairs; ETC; electron transport chain; mtEFTu, mtEFG1 and mtEFTs; mitochondrial elongation factor Tu, G1 and Ts; MMP;
Gastrin mediates resistance to hypoxia-induced cell death in xenografts of the human colorectal cancer cell line LoVo
Keywords: فاکتور القای هیپوکسی -1; CCK2R; cholecystokinin 2 receptor; CRC; colorectal cancer; Gamide; amidated gastrin; Ggly; glycine-extended gastrin; PG; progastrin; HB-EGF; heparin-binding epidermal growth factor-like growth factor; HIF-1; hypoxia-inducible factor-1; VEGF; vascular endo
Increased Expression of EIF5A2, Via Hypoxia or Gene Amplification, Contributes to Metastasis and Angiogenesis of Esophageal Squamous Cell Carcinoma
Keywords: فاکتور القای هیپوکسی -1; Oxygen; Gene Regulation; EMT; Oncogene; ChIP; chromatin immunoprecipitation; eIF5A2; eukaryotic initiation factor 5A2; EMT; epithelial-to-mesenchymal transition; ESCC; esophageal squamous cell carcinoma; FISH; fluorescence in situ hybridization; HIF-1; hy
Phenethyl isothiocyanate inhibits hypoxia-induced accumulation of HIF-1α and VEGF expression in human glioma cells
Keywords: فاکتور القای هیپوکسی -1; PEITC; phenethyl isothiocyanate; PAGE; polyacrylamide gel electrophoresis; PBS; phosphate-buffered saline; SDS; sodium dodecyl sulphate; HIF-1α; hypoxia-inducible factor-1; VEGF; vascular endothelial growth factor; uPA; urokinase-type plasminogen activat
β-Adrenergic system, a backstage manipulator regulating tumour progression and drug target in cancer therapy
Keywords: فاکتور القای هیپوکسی -1; FAK; focal adhesion kinase; PKA; protein kinase A; BAD; BCL2-associated death protein; VEGF; vascular endothelial growth factor; PlGF; placenta-derived growth factor; PDGF; platelet-derived growth factor; TGF-β; transforming growth factor β; HIF-1α; hy
A1 and A3 adenosine receptors inhibit LPS-induced hypoxia-inducible factor-1 accumulation in murine astrocytes
Keywords: فاکتور القای هیپوکسی -1; ActD; actinomycin D; Ado; adenosine; ADA; adenosine deaminase; BAY 60-6583; 2-[[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide; CHA; N(6)-cyclohexyladenosine; CGS 21680; 2-p-(2-carboxyethyl)phenethylamino-5â²-N-ethylcarb
Inhibition of autophagy with chloroquine is effective in melanoma
Keywords: فاکتور القای هیپوکسی -1; Melanoma; Chloroquine; Echinomycin; Hypoxia-inducible factor-1; Heat shock protein 90; Autophagy; Autophagy inhibition; Autophagosome; Cancer hypoxia