Keywords: GEO; NCBI Gene Expression Omnibus; GES; Gene Expression Signature; TCT; Tocotrienols; LB; Lactobacillus; AMF; Amorfrutin; I3C; Indole-3-carbinol; RSM; Rosemary; CA; Carnosic Acid; WFNA; Withaferin A; SFN; Sulforaphane; RVT; Resveratrol; TRVT; Transresvera
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Keywords: AhR; aryl hydrocarbon receptor; AhR-KO; AhR-deficient mouse; AhRÎK5; keratinocyte-specific AhR-deficient; AhRÎLC; Langerhans cell-specific AhR-deficient; ALD; AhR-ligand-free synthetic diet plus indole-3-carbinol; DRE; dioxin responsive elements; FICZ
Evaluating of OCT-4 and NANOG was differentially regulated by a new derivative indole in leukemia cell line
Keywords: NI-3-CD; new indole-3-carbaldehyde derivative; I3C; indole-3-carbaldehyde; APL; acute promyelocytic leukemia; AML; aacute myeloid leukemia; Oct-4; octamer-binding transcription factor 4; ES; eembryonic stem; HNSCC; head and neck squamous cell carcinoma; N
Dietary broccoli impacts microbial community structure and attenuates chemically induced colitis in mice in an Ah receptor dependent manner
Keywords: AHR; ICZ; Indole-3-carbinol; Broccoli; Intestinal homeostasis; Ah receptor; Glucobrasscin (PubChem CID: 6602378); Indole-3-carbinol (PubChem CID: 3712); 3,3â²-Diindolylmethane (PubChem CID: 3071); Indolo[3,2-b]carbazole (PubChem CID: 114764); AHR; aryl h
AHR in the skin: From the mediator of chloracne to a therapeutic panacea?
Keywords: Arylhydrocarbon receptor; Skin; Inflammation; Dietary ligands; Air pollution; AHR; aryl hydrocarbon receptor; AHRR; AHR-repressor; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; IDO; indoleamin-2,3,-dioxygenase; NFκB; nuclear factor κB; DC; dendritic cell;
Salt and methyl jasmonate aggravate growth inhibition and senescence in Arabidopsis seedlings via the JA signaling pathway
Keywords: SaM; salinity and MeJA; IGs; indolic-glucosinolates; AGs; aliphatic-glucosinolates; I3C; indol-3-carbinol; IACN; indol-3-ylacetonitrile; Salinity; Jasmonate; Growth inhibition; Senescence; Glucosinolates;
Childhood metabolic syndrome, inflammation and carotid intima-media thickness. The Aboriginal Birth Cohort Study
Keywords: ABC; Aboriginal Birth Cohort; BMI; body mass index; CRP; C-reactive protein; i3C; International Childhood Cardiovascular Cohort; IMT; intima-media thickness; MetS; metabolic syndrome; Childhood; Indigenous; Inflammation; Intima-media thickness; Metabolic
Phase I metabolism of 3-methylindole, an environmental pollutant, by hepatic microsomes from carp (Cyprinus carpio) and rainbow trout (Oncorhynchus mykiss)
Keywords: Hepatic microsomes; 3-methylindole; 3-hydroxy-3-metyloxindole; Indole-3-carbinol; Cytochrome P450; 2-AAP; 2-aminoacetophenone; 3MI; 3-methylindole; 3MOI; 3-methyloxindole; BFC; 7-benzyloxy-4-trifluoromethylcoumarin; BFCOD; 7-benzyloxy-4-trifluoromethylcou
2,3,7,8-Tetrachlorodibenzo-p-dioxin has both pro-carcinogenic and anti-carcinogenic effects on neuroendocrine prostate carcinoma formation in TRAMP mice
Keywords: AHT; atypical hyperplasia of Tag; AHR; aryl hydrocarbon receptor; DIM; 3,3â²-diindolylmethane; I3C; indole-3-carbinol; IUL; in utero and lactational; NEPC; neuroendocrine prostate carcinoma; SAHRM; selective AHR modulator; Tag; simian virus 40 large T an
Glutathione S-transferase SlGSTE1 in Spodoptera litura may be associated with feeding adaptation of host plants
Keywords: Spodoptera litura; Midgut; Insect-plant interaction; Detoxification; Adaption; Glutathione S-transferase; BSA; bovine serium albumin; 2-DE; two-dimensional gel electrophoresis; dsRNA; double stranded RNA; DTT; DL-1,4-dithiothreitol; GAPDH; glyceraldehyd
Interferon-γ induces a tryptophan-selective amino acid transporter in human colonic epithelial cells and mouse dendritic cells
Keywords: IFN; interferon; IDO; indoleamine 2,3-dioxygenase; TDO; tryptophan dioxygenase; HPRT; hypoxanthine/guanine phosphoribosyl transferase; SLC; solute-linked carrier; LAT; l-amino acid transporter; PAT; proton-coupled amino acid transporter; MCT; monocarboxyl
Natural indoles, indole-3-carbinol and 3,3â²-diindolymethane, inhibit T cell activation by staphylococcal enterotoxin B through epigenetic regulation involving HDAC expression
Keywords: SEB; staphylococcal enterotoxin B; I3C; indole-3-carbinol; DIM; 3,3â²-diindolylmethane; HDAC; histone deacetylase; HDAC-I; class I histone deacetylase; HDAC-II; class II histone deacetylase; TSA; trichostatin A; MG; MGCD0103; MC; MC1568; Staphylococcal e
Indole-3-carbinol induces cMYC and IAP-family downmodulation and promotes apoptosis of Epstein-Barr virus (EBV)-positive but not of EBV-negative Burkitt's lymphoma cell lines
Keywords: ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related; BCL; B cell lymphoma; BIR; baculovirus IAP repeat; BL; Burkitt's lymphoma; CFLAR; CASP8 and FADD-like apoptosis regulator; cFLIP; Fas-associated death domain protein-like int
Indole-3-carbinol attenuates the deleterious gestational effects of bisphenol A exposure on the prostate gland of male F1 rats
Keywords: BPA; bisphenol A; GD; gestational day; I3C; indole-3-carbinol; PND; postnatal day; ED; endocrine disrupter; ERα; estrogen receptor α; SD; Sprague-Dawley; DMSO; dimethyl sulfoxide; G1; control group (vehicle + basal chow); G2; BPA25-treated group (25Â
Involvement of SIRT1-AMPK signaling in the protective action of indole-3-carbinol against hepatic steatosis in mice fed a high-fat diet
Keywords: I3C; indole-3-carbinol; HFD; high-fat diet; ND; normal diet; SREBP-1c; sterol regulatory element-binding protein-1c; FAS; fatty acid synthase; LPL; lipoprotein lipase; SIRT1; silent mating type information regulation 2 homolog 1; AMPK; AMP-activated prote
3,3â²-Diindolylmethane alleviates oxazolone-induced colitis through Th2/Th17 suppression and Treg induction
Keywords: AhR; aryl hydrocarbon receptor; CCK-8; Cell Counting Kit-8; DAI; disease activity index; DIM; 3,3â²-diindolylmethane; DSS; dextran sodium sulfate; EAE; experimental autoimmune encephalomyelitis; ERα; estrogen receptor α; FICZ; 6-formylindolo[3,2-b]carb
Differential modulation of dibenzo[def,p]chrysene transplacental carcinogenesis: Maternal diets rich in indole-3-carbinol versus sulforaphane
Keywords: I3C; indole-3-carbinol; SFN; sulforaphane; DBC; dibenzo[def,p]chrysene; GFN; glucoraphanin; GSH; glutathione; CG; cysteine-glycine; Cys; cysteine; NAC; N-acetylcysteine; 3-MC; 3-methylcholanthrene; DMBA; 7,12-dimethylbenz[a]anthracene; BaP; benzo[a]pyre
Increased neuronal activity in the OVLT of Cyp1a1-Ren2 transgenic rats with inducible Ang II-dependent malignant hypertension
Keywords: Ang II; angiotensin II; OVLT; organum vasculosum of the lamina terminalis; TRPV1; transient receptor potential vanilloid type 1; CNS; central nervous system; Cyp1a1; cytochrome P450 1a1; Ren2; renin gene; I3C; aryl hydrocarbon indole-3-carbinol; Cyp1a-1Re
DFT/B3LYP study of the substituent effects on the reaction enthalpies of the antioxidant mechanisms of Indole-3-Carbinol derivatives in the gas-phase and water
Keywords: I3C; Indole-3-Carbinol; IEF-PCM; integral equation formalism polarized continuum model; DFT; density functional theory; BDE; bond dissociation enthalpy; IP; ionization potential; PA; proton affinity; SET-PT; single electron transfer followed by proton tra
Indole-3-carbinol induces apoptosis through p53 and activation of caspase-8 pathway in lung cancer A549 cells
Keywords: CDKI; cyclin-dependent kinase inhibitor; I3C; indole-3-carbinol; PARP; poly (ADP-ribose) polymerase; PI3K; phosphatidylinositol 3-kinase; z-IETD-FMK; benzyloxycarbonyl-Ile-Glu (OMe)-Thr-Asp (OMe)-fluoromethyl ketone; Indole-3-carbinol; Lung cancer; A549;
Implication of microRNAs in drug resistance for designing novel cancer therapy
Keywords: microRNA; Drug resistance; Cancer therapy; Isoflavone; DIM; I3C; Curcumin; EGCG
Indole-3-carbinol improves survival in lupus-prone mice by inducing tandem B- and T-cell differentiation blockades
Keywords: I3C, Indole-3-carbinol; 2-OH, 2-hydroxylated; 16α-OH, 16α-hydroxylatedSystemic lupus erythematosus; B lymphocytes; T lymphocytes; SLE; Lymphocyte maturation; Autoantibodies; Estrogen; I3C; Renal disease; Cytokines
Cancer chemotherapy with indole-3-carbinol, bis(3′-indolyl)methane and synthetic analogs
Keywords: I3C; DIMs; Anticarcinogenesis; Nur77; PPAR
Indole-3-carbinol and 3,3â²-diindolylmethane induce expression of NAG-1 in a p53-independent manner
Keywords: I3C; GDF-15; NAG-1; ATF3; p53; DIM; Apoptosis;
Induction of phase-1 metabolizing enzymes by oltipraz, flavone and indole-3-carbinol enhance the formation and transport of benzo[a]pyrene sulfate conjugates in intestinal Caco-2 cells
Keywords: ABC; ATP-binding cassette; AhR; aryl hydrocarbon receptor; BP; benzo[a]pyrene; 3-OH-BP; 3-hydroxybenzo[a]pyrene; INF; indeno[1,2,3-cd]fluoranthene; 3-MC; 3-methylcholanthrene; β-NF; β-naphthoflavone; CYP; cytochrome P450; DMSO; dimethylsulfoxide; GST; g
Modulation of apoptosis by cancer chemopreventive agents
Keywords: 5,6-BF; 5,6-benzoflavone; BITC; benzyl isothiocyanate; DFMO; difluoromethylornithine; 1,2-D3T; 1,2-dithiole-3-thione; ECS; environmental cigarette smoke; EGCG; epigallocatechin gallate; GSH; reduced glutathione; 4-HPR; N-(4-hydroxyphenyl) retinamide; I3C;