Increased neuronal activity in the OVLT of Cyp1a1-Ren2 transgenic rats with inducible Ang II-dependent malignant hypertension

► C-fos expression increased in the OVLT of Cyp1a1-Ren2 rats with Ang II-dependent hypertension. ► TRPV1 protein expression increased in the OVLT of Cyp1a1-Ren2 rats with malignant hypertension. ► Cyp1a1-Ren2 rat is a relevant model of pharmacologically induced Ang II-dependent hypertension.