Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; Microcirculation; Laser Doppler flux; Pressure-induced vasodilation; Endothelium dysfunction; Transient receptor potential vanilloid type 1;
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Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; Opioids; Analgesia; Adverse effects; Mechanisms; Constipation; Nausea; Vomiting; Respiratory depression; 5-HT; 5-hydroxytryptamine; 7TMRs; 7-transmembrane spanning G-protein coupled receptors; AC; adenylyl cyclase; β-arr1; β-arrestin1; β-arr2; β-arres
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; Esophageal motility; Trypsin; Proteinase-activated receptors; Transient receptor potential vanilloid type 1; Substance P; Neurokinin receptors;
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; Atopy; transient receptor potential vanilloid type 1; vagus; pharmacodynamic modeling; ACQ; Asthma Control Questionnaire; ATS; American Thoracic Society; C2; Concentration of capsaicin inducing at least 2 coughs; C5; Concentration of capsaicin inducing at
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; Visceral Hyperalgesia; HPA; Epigenetic Modification; Pain Sensitivity; ChIP; chromatin immunoprecipitation; CNR1; cannabinoid receptor 1; CNS; central nervous system; CORT; corticosterone; CRD; colorectal distension; DNMT; DNA (cytosine-5-)-methyltransfer
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; BMI; body mass index; OVX; ovariectomy; CPT-1; carnitine palmitoyltransferase-1; ACC; acetyl CoA carboxylase; SREBP-1c; sterol regulatory element-binding protein-1c; FAS; fatty acid synthase; LSP; less pungent red pepper; MSP; moderately pungent red peppe
Design, synthesis and biological evaluation of N1-(isoquinolin-5-yl)-N2-phenylpyrrolidine-1,2-dicarboxamide derivatives as potent TRPV1 antagonists
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; Analgesic; Transient receptor potential vanilloid type 1; 5-Aminoisoquinoline urea; Hyperthermia;
Long Non-coding RNA BC168687 is Involved in TRPV1-mediated Diabetic Neuropathic Pain in Rats
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; DNP; diabetic neuropathic pain; DRG; dorsal root ganglia; FPG; fasting plasma glucose; lncRNAs; long noncoding RNAs; MAPK; mitogen-activated protein kinase; MWT; mechanical withdrawal thresholds; PBS; phosphate buffer saline; PNS; peripheral nervous syste
GABAA receptor activity modulating piperine analogs: In vitro metabolic stability, metabolite identification, CYP450 reaction phenotyping, and protein binding
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; au; arbitrary units; BBB; blood brain barrier; CNS; central nervous system; CYP450; cytochrome P450; DMSO; dimethyl sulfoxide; ESI; electrospray ionization; GABAA; γ- aminobutyric acid type A receptor; HPLC; high performance liquid chromatography; HR; hi
Downregulated TRPV1 Expression Contributes to Melanoma Growth via the Calcineurin-ATF3-p53 Pathway
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; qRT-PCR; quantitative real-time PCR; TRPV1; transient receptor potential vanilloid type 1;
Botulinum toxin type A reduces TRPV1 expression in the dorsal root ganglion in rats with adjuvant-arthritis pain
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; Botulinum toxin type A; Transient receptor potential vanilloid type 1; Arthritis pain; Retrograde axonal transport; Dorsal root ganglion;
Curcumin synergizes with the endocannabinoid reuptake inhibitor OMDM-2 in human MCF-7 breast cancer and U-87 glioblastoma cells
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; Î9-THC; Delta-9-tetrahydrocannabinol; 2-AG; 2-arachidonoylglycerol; AEA; Anandamide; BCL2; B-cell CLL/lymphoma 2; CB-1; Cannabinoid receptor 1; CB-2; Cannabinoid receptor 2; CI; Combination Index; CXCR4; chemokine receptor type 4; DDS; Drug delivery syst
Enhanced anandamide signaling reduces flight behavior elicited by an approaching robo-beetle
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; Panic; Anandamide; URB597; 2-AG; JZL184; Active-fear; Robo-beetle; Inbred mice; 2-AG; 2-arachidonoylglycerol; AEA; anandamide; BMT; beetle mania task; CB1; cannabinoid receptor 1; FAAH; fatty acid amide hydrolase; HAB; high-anxiety behavior; MAGL; monoacy
Research articleBlocking of TRPV-1 in the parodontium relieves orthodontic pain by inhibiting the expression of TRPV-1 in the trigeminal ganglion during experimental tooth movement in rats
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; TRPV1; transient receptor potential vanilloid type 1; TG; trigeminal ganglion; TRP; transient receptor potential; PFA; paraformaldehyde; qRT-PCR; quantitative realtime PCR; DMSO; dimethylsulfoxide; GCF; gingival crevicular fluid; IL-1β; interleukin-1β;
Design, synthesis and biological evaluation of novel analgesic agents targeting both cyclooxygenase and TRPV1
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; Analgesic; Transient receptor potential vanilloid type 1; Cyclooxygenase; Hyperthermia
The role of TRPV1 in improving VSMC function and attenuating hypertension
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; Transient receptor potential vanilloid type 1; Hypertension; Vascular smooth muscle cells; Neurotransmitters; Calcium ion; Inflammation;
Involvement of apoptosis and calcium accumulation through TRPV1 channels in neurobiology of epilepsy
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; [Ca2+]i; intracellular Ca2+; CAP; capsaicin; CHAPS; 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate; CPZ; capsazepine; DMSO; dimethyl sulfoxide; DRG; dorsal root ganglion; DTT; Dithiothreitol; EEG; electroencephalography; EGTA; ethylene glycol-b
Inhibition of FAAH, TRPV1, and COX2 by NSAID-serotonin conjugates
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; NSAID; FAAH; Fatty acid amide hydrolase; TRPV1; Transient receptor potential vanilloid type 1; Dual inhibition; Multimodal inhibition; Arachidonoyl serotonin;
Increased neuronal activity in the OVLT of Cyp1a1-Ren2 transgenic rats with inducible Ang II-dependent malignant hypertension
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; Ang II; angiotensin II; OVLT; organum vasculosum of the lamina terminalis; TRPV1; transient receptor potential vanilloid type 1; CNS; central nervous system; Cyp1a1; cytochrome P450 1a1; Ren2; renin gene; I3C; aryl hydrocarbon indole-3-carbinol; Cyp1a-1Re
TRPV1 antagonist can suppress the atopic dermatitis-like symptoms by accelerating skin barrier recovery
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; Transient receptor potential vanilloid type 1; Atopic dermatitis; Skin barrier; PAC-14028; Filaggrin; Loricrin
Corticosterone Mediates Reciprocal Changes in CB 1 and TRPV1 Receptors in Primary Sensory Neurons in the Chronically Stressed Rat
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; Visceral Hyperalgesia; Visceral Motor Response; Water Avoidance Stress; Dorsal Root Ganglion; AEA; endocannabinoid anandamide; CB1; cannabinoid receptor 1; COX-2; cyclooxygenase-2; CRD; colorectal distension; CRF; corticotrophin releasing factor; CTB; chl
Modulation of μ-opioid receptor desensitization in peripheral sensory neurons by phosphoinositide 3-kinase γ
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; MOR; PI3Kγ; DRG; VGCC; desensitization; opioid tolerance; DAMGO; D-Ala2,N-Me-Phe4,Gly5-ol-enkephalin; DRG; dorsal root ganglion; GPCR; G protein-coupled receptor; MOR; μ-opioid receptor; PI3K; phosphoinositide 3-kinase, class 1; TRPV1; transient recepto
5-Lipoxygenase in mouse cerebellar Purkinje cells
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; 5-Lipoxygenase; cerebellum; Purkinje cell; Dicer; DNA methylation; FLAP; CaBP-28; calbindin 28-kDa protein; DEPC; diethylpyrocarbonate; DIG; digoxigenin; FLAP; 5-lipoxygenase activating protein; LCM; laser capture microdissection; LTB4; leukotriene B4; M-
Effects of capsazepine, a transient receptor potential vanilloid type 1 antagonist, on morphine-induced antinociception, tolerance, and dependence in mice
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; capsazepine; hot-plate test; morphine; transient receptor potential vanilloid type 1; withdrawal symptoms;
Immunoreactivity of oxytocin receptor and transient receptor potential vanilloid type 1 and its correlation with dysmenorrhea in adenomyosis
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; adenomyosis; dysmenorrhea; immunohistochemistry; oxytocin receptor; severity; transient receptor potential vanilloid type 1;
The synaptic connectivity that underlies the noxious transmission and modulation within the superficial dorsal horn of the spinal cord
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; AMPA; alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic; CB; calbindin-D28K; CGRP; calcitonin gene-related peptide; CTb; cholera toxin subunit b; CVLM; caudal ventrolateral medulla; DLF; dorsolateral fasciculus; DOR; δ-opioid receptor; DR; dorsal root;
Capsaicin-sensitive primary sensory neurons in the mouse express N-Acyl phosphatidylethanolamine phospholipase D
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; anandamide; dorsal root ganglion; transient receptor vanilloid type 1; TRPV1; nociceptive; pain; anandamide; N-arachidonoyl ethanolamine; CB1; cannabinoid 1; CB2; cannabinoid 2; DRG; dorsal root ganglia; FAAH; fatty acid amide hydrolase; GAPDH; glyceralde
Involvement of capsaicin-sensitive afferent nerves in the proteinase-activated receptor 2–mediated vasodilatation in the rat dura mater
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; meningeal blood flow; headache; transient receptor potential vanilloid type 1; laser Doppler flowmetryCGRP, calcitonin gene-related peptide; HEPES, 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid; l-NAME, Nω-nitro-l-arginine methyl ester hydrochloride;
Role of TRPV1 receptors in descending modulation of pain
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; Endocannabinoids; Transient receptor potential vanilloid type 1; Periaqueductal grey; Rostral ventromedial medulla; ON and OFF cells; Pain
Increased GFR and renal excretory function by activation of TRPV1 in the isolated perfused kidney
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; Transient receptor potential vanilloid type 1; Glomerular filtration rate; Isolated perfused kidney; Capsaicin;
Roles of dorsal column pathway and transient receptor potential vanilloid type 1 in augmentation of cerebral blood flow by upper cervical spinal cord stimulation in rats
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; spinal cord stimulation; cerebral ischemia; vasodilation; transient receptor potential vanilloid type 1; resiniferatoxin; CBF; cerebral blood flow; cSCS; cervical spinal cord stimulation; CVR; cerebrovascular resistance; i.t.; intrathecal, intrathecally;
Relative roles of protein kinase A and protein kinase C in modulation of transient receptor potential vanilloid type 1 receptor responsiveness in rat sensory neurons in vitro and peripheral nociceptors in vivo
Keywords: پتانسیل ترانزیتی وینیلوئید نوع 1; capsaicin; resiniferatoxin; Ca2+ imaging; noxious heat threshold; increasing-temperature hot plate; ANOVA; analysis of variance; dbcAMP; dibutyryl cyclic AMP; DMEM; Dulbecco's Modified Eagle Medium; ECS; extracellular solution; EGTA; ethylene glycol-bis