Keywords: IBS; Irritable bowel syndrome; Constipation; Diarrhea; Diet; Pharmacological agents; IBS-C; IBS-D; Pathophysiology;
مقالات ISI (ترجمه نشده)
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Keywords: 5-HT; 5-hydroxytryptamine; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CAMKII; Calcium/calmodulin-dependent protein kinase II; CaV; voltage-gated calcium (channel); CGRP; calcitonin gene-related peptide; CB; cannabinoid receptor; CNS; cen
Keywords: Cholic Acid; Chenodeoxycholic Acid; 7α-Hydroxy-4-Cholesten-3-One; GPBAR1 (G-Protein-Coupled Bile Acid Receptor 1); BA; bile acid; BAM; bile acid malabsorption; C4; 7α-hydroxy-4-cholesten-3-one; CDCA; chenodeoxycholic acid; DCA; deoxycholic acid; FGF19
Keywords: IBS; irritable bowel syndrome; QoL; quality of life; IBSSS; IBS severity score system; IBS-QoL; IBS specific QoL; GI; gastrointestinal; IBS-D; diarrhea-predominant; IBS-C; constipation-predominant; IBS-A; alternating bowel habits; TNFα; tumor necrosis fa
Keywords: MT2; melatonin receptors; 5-HT; serotonin; CCK2; cholecystokinin B; IBS; irritable bowel syndrome; IBS-C; constipation-predominant IBS; IBS-D; diarrhea-predominant IBS; EC; enterochromaffin cells; GIT; gastrointestinal; NOS; nitric oxide synthase; NF-κB;
Keywords: Intestinal Permeability; Bacteria; Ketotifen; Inflammation; 51Cr-edta; 51chromium (Cr)-edta; Escherichia coli; EÂ coli; HCs; healthy controls; IBS; irritable bowel syndrome; IBS-C; IBS with constipation; IBS-D; IBS with diarrhea; IBS-M; IBS with mixed sto
Keywords: Functional Bowel Disorder; Bacteria; Microbiome; AUC; area under the curve; AUROC; area under the receiver operating characteristic curve; BMI; body mass index; FODMAP; Fermentable, Oligo-, Di-, Mono-saccharides And Polyols; GI; gastrointestinal; HAD; Hos
Keywords: FC; Functional constipation; FGID; Functional gastrointestinal disorder; GI; Gastrointestinal; IBS; Irritable bowel syndrome; IBS-C; IBS with constipation; QPGS-III; Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III Version;
Keywords: Functional Gastrointestinal Disorders; Controlled Trial; Patient-Reported Outcome Measure; Intention to Treat; BSFS; Bristol Stool Form Scale; CONSORT; Consolidated Standards for Reporting Trials; EMA; European Medicines Agency; FDA; US Food and Drug Admi
Keywords: Abdominal Pain; Bloating; Distension; Constipation; Diarrhea; Functional Bowel Disorders; Irritable Bowel Syndrome; BSFS; Bristol Stool Form Scale; CBC; complete blood count; CC; chronic constipation; DD; dyssynergic defecation; FAB; functional abdominal
Keywords: TPM; Traditional Persian Medicine; IBS; Irritable bowel syndrome; VAS; Visual analogue scale; QOL; Quality of life; IBS-C; IBS with constipation; IBS-D; IBS with diarrhea; IBS-M; IBS with a mixed pattern; IBS-UM; IBS with an unsubtyped pattern; CONSORT; C
Keywords: Pain; Diarrhea; Constipation; Animal Models; Dyspepsia; Transit; Sensation; CFTR; cystic fibrosis transmembrane regulator; cGMP; cyclic guanosine monophosphate; CYP; cytochrome P450; FD; functional dyspepsia; FDA; Food and Drug Administration; FGID; funct
Keywords: Microbiota; Dientamoeba fragilis; Blastocystis; Risk Factors; ct; cycle threshold; DKK; Danish Kroner; GI; gastrointestinal; IBS; irritable bowel syndrome; IBS-C; irritable bowel syndrome with constipation; IBS-D; irritable bowel syndrome with diarrhea; r
Keywords: Mast Cells; Enteric Nerves; Nerve Growth Factor; Growth-Associated Protein 43; IBS; irritable bowel syndrome; IBS-C; irritable bowel syndrome with constipation; IBS-D; irritable bowel syndrome with diarrhea; IBS-M; irritable bowel syndrome with mix of con
Keywords: Irritable Bowel Syndrome; IBS Subtypes; Children; Pediatric Functional GI Disorders; BSFS; Bristol Stool Form Scale; GI; gastrointestinal; IBS; irritable bowel syndrome; IBS-C; irritable bowel syndrome with constipation; IBS-D; irritable bowel syndrome wi
Keywords: Guanylate Cyclase-C; IBS-C; Abdominal Pain; Bloating; AE; adverse event; ANCOVA; analysis of covariance; BM; bowel movement; cGMP; cyclic guanosine monophosphate; CMH; Cochran-Mantel-Haenszel; GC-C; guanylate cyclase-C; IBS; irritable bowel syndrome; IB
Keywords: IBS; Irritable Bowel Syndrome; IBS-D; IBS diarrhea predominant; IBS-C; IBS constipation predominant; IBS-A; IBS alternating; PBMC; peripheral blood mononuclear cell; MALDI-TOF; matrix-assisted laser desorption/ionization-time of flight; MOR; μ-opioid rec
Keywords: AGA; American Gastroenterological Association; CI; confidence interval; CSBM; complete spontaneous bowel movement; FDA; Food and Drug Administration; GRADE; Grading of Recommendations Assessment, Development and Evaluation; IBS; irritable bowel syndrome;
Increased Prevalence of Rare Sucrase-isomaltase Pathogenic Variants in Irritable Bowel Syndrome Patients
Keywords: CADD; Combined Annotation Dependent Depletion; CSID; congenital sucrase-isomaltase deficiency; ExAC; Exome Aggregation Consortium; IBS; irritable bowel syndrome; IBS-C; IBS with constipation; IBS-D; IBS with diarrhea; M-CAP; Mendelian Clinically Applicabl
Association between SERT insertion/deletion polymorphism and the risk of irritable bowel syndrome: A meta-analysis based on 7039 subjects
Keywords: SERT; Serotonin transporter; IBS; Irritable bowel syndrome; IBS-D; Diarrhea predominant IBS; IBS-C; Constipation predominant IBS; IBS-M; Mixture of diarrhea and constipation IBS; HWE; Hardy-Weinberg equilibrium; NOS; Newcastle-Ottawa scale; Serotonin tran
Neuromodulators for Functional Gastrointestinal Disorders (Disorders of GutâBrain Interaction): A Rome Foundation Working Team Report
Keywords: Functional Gastrointestinal Disorders; Central Neuromodulators; Antidepressants; Antipsychotics; Disorders of Gut Brain Interaction; Chronic Abdominal Pain; CBT; cognitive behavioral therapy; CNS; central nervous system; CVS; cyclic vomiting syndrome; D2;
Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation
Keywords: CFTR; cystic fibrosis transmembrane conductance regulator; CIC; chronic idiopathic constipation; OIC; opioid-induced constipation; IBS-C; constipation-predominant irritable bowel syndrome; ppm; parts per million; PBS; phosphate-buffered saline; LC/MS; liq
Lubiprostone Is Effective in the Treatment of Chronic Idiopathic Constipation and Irritable Bowel Syndrome
Keywords: CIC; chronic idiopathic constipation; IBS-C; irritable bowel syndrome with constipation; RCT; randomized controlled trial;
Lubiprostone Increases Spontaneous Bowel Movement Frequency and Quality of Life in Patients With Chronic Idiopathic Constipation
Keywords: IBS; Rome III Criteria; Functional Disorder; QOL; Intestine; Small-Bowel Transit; CIC; chronic idiopathic constipation; FAS; full-analysis set; GI; gastrointestinal; IBS; irritable bowel syndrome; IBS-C; irritable bowel syndrome with constipation; QOL; qu
MicroRNA 29 Targets Nuclear Factor-κB-Repressing Factor and Claudin 1 to Increase Intestinal Permeability
Keywords: Gene Regulation; mRNA Processing; Intestinal Barrier Function; Mouse Model; CLDN1; Claudin-1; IBS; irritable bowel syndrome; IBS-C; constipation-predominant irritable bowel syndrome; IBS-D; diarrhea-predominant irritable bowel syndrome; miRNA; microRNA; m
Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome
Keywords: Pain; Proteolytic Activity; Protease; PAR2; AA; arachidonic acid; CRD; colorectal distension; COX; cyclooxygenase; CYPe; cytochrome epoxygenase; DRG; dorsal root ganglia; EET; epoxyeicosatrienoic acid; FB; Fast Blue; HC; healthy control; HETE; hydroxyeico
A Diet Low in FODMAPs Reduces Symptoms of Irritable Bowel Syndrome
Keywords: Clinical Trial; Food Intolerance; Abdominal Pain; Short-Chain Carbohydrates; FODMAP; fermentable oligosaccharides, disaccharides, monosaccharides, and polyol; FWC; fecal water content; IBS; irritable bowel syndrome; IBS-C; constipation-predominant irritab
Original ResearchFull Report: Clinical-Alimentary TractRome III Functional Constipation and Irritable Bowel Syndrome With Constipation Are Similar Disorders Within a Spectrum of Sensitization, Regulated by Serotonin
Keywords: Visceral Sensitivity; 5-Hydroxytryptamine; 5-HT; Neurotransmitter; EC; enterochromaffin; FC; functional constipation; 5-HT; 5-hydroxytryptamine; HV; healthy volunteer; IBS-C; irritable bowel syndrome with constipation; IBS-D; irritable bowel syndrome with
Original ResearchFull Report: Basic and Translational-Alimentary TractLinaclotide Inhibits Colonic Nociceptors and Relieves Abdominal Pain via Guanylate Cyclase-C and Extracellular Cyclic Guanosine 3â²,5â²-Monophosphate
Keywords: CVH; CRD; Signaling Transduction; Analgesia; cGMP; cyclic guanosine-3â²,5â²-monophosphate; CRD; colorectal distention; CVH; chronic visceral hypersensitivity; DH; dorsal horn; GC-C; guanylate cyclase-C; IBS; irritable bowel syndrome; IBS-C; irritable bo
Effects of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation or Chronic Constipation: A Meta-analysis
Keywords: Functional Bowel; Colon; Systematic Review; Clinical Trials; BSFS; Bristol Stool Form Scale; CC; chronic constipation; CI; confidence interval; CSBM; complete spontaneous bowel movement; FDA; Food and Drug Administration; IBS-C; irritable bowel syndrome w
American Gastroenterological Association Technical Review on Constipation
Keywords: AGA; American Gastroenterological Association; CFTR; cystic fibrosis transmembrane regulator; FDA; Food and Drug Administration; IBS; irritable bowel syndrome; IBS-C; constipation-predominant irritable bowel syndrome; IRA; ileorectal anastomosis; NTC; nor
Increased Risk of Miscarriage and Ectopic Pregnancy Among Women With Irritable Bowel Syndrome
Keywords: Abdominal Pain; Bloating; Intestinal; Pregnant; Complication; BMI; body mass index; CI; confidence interval; GPRD; General Practice Research Database; IBD; inflammatory bowel disease; IBS; irritable bowel syndrome; IBS-C; constipation-predominant irritabl
Increased Bile Acid Biosynthesis Is Associated With Irritable Bowel Syndrome With Diarrhea
Keywords: Colon; Malabsorption; Liver; Metabolism; BA; bile acid; BAM; bile acid malabsorption; BMI; body mass index; C4; 7α-hydroxy-4-cholesten-3-one; FGF; fibroblast growth factor; FGFR4; fibroblast growth factor receptor 4; HV; healthy volunteers; IBS; irritabl
Global Prevalence of and Risk Factors for Irritable Bowel Syndrome: A Meta-analysis
Keywords: Abdominal Pain; Bloating; Incidence; Rate; CI; confidence interval; GI; gastrointestinal; IBS; irritable bowel syndrome; IBS-C; constipation-predominant irritable bowel syndrome; IBS-D; diarrhea-predominant irritable bowel syndrome; IBS-M; mixed stool pat
Development and Validation of the Irritable Bowel Syndrome Satisfaction With Care Scale
Keywords: Quality of Care; Bloating; Abdominal Pain; Treatment; FBDSI; Functional Bowel Disorders Severity Index; IBS; irritable bowel syndrome; IBS-C; irritable bowel syndrome with constipation; IBS-M; mixed irritable bowel syndrome; IBS-QOL; Irritable Bowel Syndr
Original ResearchBasic and Translational-Alimentary TractGlobal and Deep Molecular Analysis of Microbiota Signatures in Fecal Samples From Patients With Irritable Bowel Syndrome
Keywords: High-Throughput Analysis; Phylogenetic Microarray; Microflora; Enterotypes; HITChip; human intestinal tract chip; IBS; irritable bowel syndrome; IBS-C; constipation-predominant IBS; IBS-D; diarrhea-predominant IBS; IBS-A; alternating-type IBS; qPCR; quant
Pharmacogenetic Trial of a Cannabinoid Agonist Shows Reduced Fasting Colonic Motility in Patients With Nonconstipated Irritable Bowel Syndrome
Keywords: Sensory; Motor; Clinical Trial; Drug Metabolism; FAAH; fatty acid amide hydrolase; IBS-A; irritable bowel syndrome alternating; IBS-C; irritable bowel syndrome with constipation; IBS-D; irritable bowel syndrome with diarrhea; MGLL; monoacylglycerol lipase
The Con Argument
Keywords: BAM; bile acid malabsorption; BM; bowel movements; FC; functional constipation; FDD; functional defecation disorders; FGID; functional gastrointestinal disorders; IBS; irritable bowel syndrome; IBS-C; irritable bowel syndrome with constipation; IBS-D; irr
Chenodeoxycholate in Females With Irritable Bowel Syndrome-Constipation: A Pharmacodynamic and Pharmacogenetic Analysis
Keywords: Bile Acid; 7αC4; FGF19; FGFR4; AC; ascending; ANCOVA; analysis of covariance; BMI; body mass index; CDC; (sodium) chenodeoxycholate; CF6; colonic filling at 6 hours; FGF19; fibroblast growth factor 19; FGFR4; fibroblast growth factor receptor 4; GC; geom
Alterations in Mucosal Immunity Identified in the Colon of Patients With Irritable Bowel Syndrome
Keywords: ANOVA; analysis of variance; CCC; concordance correlation coefficient; gcRMA; guanosine cytosine robust multi-chip average; IBS; irritable bowel syndrome; IBS-C; constipation-predominant irritable bowel syndrome; IBS-D; diarrhea-predominant irritable bowe
A Pilot Study of Fecal Serine-Protease Activity: A Pathophysiologic Factor in Diarrhea-Predominant Irritable Bowel Syndrome
Keywords: IBS; irritable bowel syndrome; IBS-A; irritable bowel syndrome with alternating habits; IBS-C; constipation-predominant irritable bowel syndrome; IBS-D; diarrhea-predominant irritable bowel syndrome; PAR; proteinase-activated receptor; SLPI; secretory leu
Efficacy of On-Demand Asimadoline, a Peripheral κ-Opioid Agonist, in Females With Irritable Bowel Syndrome
Keywords: BDQ; Bowel Disease Questionnaire; df; degrees of freedom; HADS; Hospital Anxiety and Depression Scale; IBS; irritable bowel syndrome; IBS-C; constipation-predominant irritable bowel syndrome; IBS-D; diarrhea-predominant irritable bowel syndrome; IBS-M; ir
Role of Colonic Fermentation in the Perception of Colonic Distention in Irritable Bowel Syndrome and Functional Bloating
Keywords: ANOVA; analysis of variance; FB; functional abdominal bloating; IBS-C; constipation-predominant irritable bowel syndrome; IBS-D; diarrhea-predominant irritable bowel syndrome; SCFAs; short-chain fatty acids;
Relationship of Abdominal Bloating to Distention in Irritable Bowel Syndrome and Effect of Bowel Habit
Keywords: CI; confidence interval; IBS-alt; irritable bowel syndrome with alternating bowel habits; IBS-C; irritable bowel syndrome with constipation; IBS-D; irritable bowel syndrome with diarrhea;
The AmpliChip CYP450 Test: Principles, Challenges, and Future Clinical Utility in Digestive Disease
Keywords: ADR; adverse drug reaction; IBS-C; constipation-predominant irritable bowel syndrome; CYP450; cytochrome P450; IBS-D; diarrhea-predominant irritable bowel syndrome; EM; extensive metabolizer; GERD; gastroesophageal reflux disease; IBS; irritable bowel syn
Safety and Tolerability of Tegaserod in Patients With Chronic Constipation: Pooled Data From Two Phase III Studies
Keywords: AEs; adverse events; CC; chronic constipation; CK; creatine kinase; CSBM; complete spontaneous bowel movement; ECG; electrocardiogram; GI; gastrointestinal; 5-HT; 5-hydroxytryptamine; IBS-C; irritable bowel syndrome with constipation; MedDRA; Medical Dict
A prospective assessment of bowel habit in irritable bowel syndrome in women: Defining an alternator
Keywords: IBS; irritable bowel syndrome; IBS-A; alternating irritable bowel syndrome; IBS-C; irritable bowel syndrome with constipation; IBS-D; irritable bowel syndrome with diarrhea; IBS-M; mixed irritable bowel syndrome;