Keywords: IBS; Irritable bowel syndrome; Constipation; Diarrhea; Diet; Pharmacological agents; IBS-C; IBS-D; Pathophysiology;
مقالات ISI (ترجمه نشده)
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Keywords: 5-HT; 5-hydroxytryptamine; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; CAMKII; Calcium/calmodulin-dependent protein kinase II; CaV; voltage-gated calcium (channel); CGRP; calcitonin gene-related peptide; CB; cannabinoid receptor; CNS; cen
Keywords: Functional Bowel Disorder; Low FODMAP Diet; Probiotics; Microbiome; FODMAPs; fermentable oligosaccharides, disaccharides, monosaccharides, and polyols; GC-MS; gas chromatography-mass spectrometry; IBS; irritable bowel syndrome; IBS-D; diarrhea-predomina
Keywords: Cholic Acid; Chenodeoxycholic Acid; 7α-Hydroxy-4-Cholesten-3-One; GPBAR1 (G-Protein-Coupled Bile Acid Receptor 1); BA; bile acid; BAM; bile acid malabsorption; C4; 7α-hydroxy-4-cholesten-3-one; CDCA; chenodeoxycholic acid; DCA; deoxycholic acid; FGF19
Keywords: FAERS Search; Sphincter of Oddi Dysfunction; Functional Gastrointestinal Disorders; IBS; FAERS; Federal Adverse Event Reporting System; FDA; Food and Drug Administration; IBS-D; diarrhea-predominant irritable bowel syndrome; SOD; sphincter of Oddi dysfunc
Keywords: QALY; Modeling; Budget Impact; Diagnostic; CMS; Centers for Medicare & Medicaid Services; CRP; C-reactive protein; FGID; functional gastrointestinal disorder; FODMAP; fermentable oligo-, di-, mono-saccharides, and polyols; IBD; inflammatory bowel disease;
Keywords: IBS; irritable bowel syndrome; QoL; quality of life; IBSSS; IBS severity score system; IBS-QoL; IBS specific QoL; GI; gastrointestinal; IBS-D; diarrhea-predominant; IBS-C; constipation-predominant; IBS-A; alternating bowel habits; TNFα; tumor necrosis fa
Keywords: MT2; melatonin receptors; 5-HT; serotonin; CCK2; cholecystokinin B; IBS; irritable bowel syndrome; IBS-C; constipation-predominant IBS; IBS-D; diarrhea-predominant IBS; EC; enterochromaffin cells; GIT; gastrointestinal; NOS; nitric oxide synthase; NF-κB;
Keywords: Intestinal Permeability; Bacteria; Ketotifen; Inflammation; 51Cr-edta; 51chromium (Cr)-edta; Escherichia coli; EÂ coli; HCs; healthy controls; IBS; irritable bowel syndrome; IBS-C; IBS with constipation; IBS-D; IBS with diarrhea; IBS-M; IBS with mixed sto
Keywords: CDCA; Lithocholate; Intestine; Clinical Study; BA; bile acids; BAM; bile acid malabsorption; CA; cholic acid; CDCA; chenodeoxycholic acid; DCA; deoxycholic acid; IBS-D; irritable bowel syndrome-diarrhea; LCA; lithocholic acid; TGR5/GpBAR1; G protein cou
Keywords: Diarrhea; Pathophysiology; Management; ATPase; adenosine triphosphatase; cAMP; cyclic adenosine monophosphate; Cg; chromogranin; cGMP; cyclic guanosine monophosphate; ENaC; epithelial sodium channel; 5-HT; 5-hydroxytryptamine; FODMAP; fermentable oligosac
Keywords: Functional Bowel Disorder; Bacteria; Microbiome; AUC; area under the curve; AUROC; area under the receiver operating characteristic curve; BMI; body mass index; FODMAP; Fermentable, Oligo-, Di-, Mono-saccharides And Polyols; GI; gastrointestinal; HAD; Hos
Keywords: EGD; esophagogastroduodenoscopy; GI; gastrointestinal; GOO; gastric outlet obstruction; GRSs; gas-related symptoms; IBS; irritable bowel syndrome; IBS-D; irritable bowel syndrome-diarrhea; SBO; small bowel obstruction; SIBO; small intestine bacterial ov
Keywords: Bloating; Functional Bowel Disease; Nonabsorbed; Xifaxan; AE; adverse event; IBS-D; diarrhea-predominant irritable bowel syndrome; TARGET; targeted, nonsystemic antibiotic rifaximin gut-selective evaluation of treatment for IBS-D; TID; three times daily;
Keywords: AGA; American Gastroenterological Association; BA; bile acid; EALs; early adverse life events; FGID; functional gastrointestinal disorder; IBS; irritable bowel syndrome; IBS-D; IBS with diarrhea; SCFA; short chain fact acid; TRPV; transient receptor poten
Keywords: Functional Gastrointestinal Disorders; Controlled Trial; Patient-Reported Outcome Measure; Intention to Treat; BSFS; Bristol Stool Form Scale; CONSORT; Consolidated Standards for Reporting Trials; EMA; European Medicines Agency; FDA; US Food and Drug Admi
Keywords: Abdominal Pain; Bloating; Distension; Constipation; Diarrhea; Functional Bowel Disorders; Irritable Bowel Syndrome; BSFS; Bristol Stool Form Scale; CBC; complete blood count; CC; chronic constipation; DD; dyssynergic defecation; FAB; functional abdominal
Keywords: TPM; Traditional Persian Medicine; IBS; Irritable bowel syndrome; VAS; Visual analogue scale; QOL; Quality of life; IBS-C; IBS with constipation; IBS-D; IBS with diarrhea; IBS-M; IBS with a mixed pattern; IBS-UM; IBS with an unsubtyped pattern; CONSORT; C
Keywords: Pain; Diarrhea; Constipation; Animal Models; Dyspepsia; Transit; Sensation; CFTR; cystic fibrosis transmembrane regulator; cGMP; cyclic guanosine monophosphate; CYP; cytochrome P450; FD; functional dyspepsia; FDA; Food and Drug Administration; FGID; funct
Keywords: AE; adverse event; CDAI; Crohn's Disease Activity Index; EIR; extended intestinal release; IBS; irritable bowel syndrome; IBS-D; diarrhea-predominant irritable bowel syndrome;
Keywords: Microbiota; Dientamoeba fragilis; Blastocystis; Risk Factors; ct; cycle threshold; DKK; Danish Kroner; GI; gastrointestinal; IBS; irritable bowel syndrome; IBS-C; irritable bowel syndrome with constipation; IBS-D; irritable bowel syndrome with diarrhea; r
Keywords: Mast Cells; Enteric Nerves; Nerve Growth Factor; Growth-Associated Protein 43; IBS; irritable bowel syndrome; IBS-C; irritable bowel syndrome with constipation; IBS-D; irritable bowel syndrome with diarrhea; IBS-M; irritable bowel syndrome with mix of con
Keywords: Irritable Bowel Syndrome; IBS Subtypes; Children; Pediatric Functional GI Disorders; BSFS; Bristol Stool Form Scale; GI; gastrointestinal; IBS; irritable bowel syndrome; IBS-C; irritable bowel syndrome with constipation; IBS-D; irritable bowel syndrome wi
Keywords: μOR-δOR heteromer; Anti-diarrhea; Eluxadoline; Loperamide; Irritable bowel syndrome; GI; gastrointestinal; IBS-d; irritable bowel syndrome with diarrhea; μOR; mu opioid receptor; δOR; delta opioid receptor; βgal; beta-galactosidase; GTPγS; guanosine
Keywords: IBS; Irritable Bowel Syndrome; IBS-D; IBS diarrhea predominant; IBS-C; IBS constipation predominant; IBS-A; IBS alternating; PBMC; peripheral blood mononuclear cell; MALDI-TOF; matrix-assisted laser desorption/ionization-time of flight; MOR; μ-opioid rec
Keywords: AGA; American Gastroenterological Association; CI; confidence interval; CSBM; complete spontaneous bowel movement; FDA; Food and Drug Administration; GRADE; Grading of Recommendations Assessment, Development and Evaluation; IBS; irritable bowel syndrome;
Keywords: Psychologic Factors; Discomfort; Psychiatric; Nervous SystemANS, autonomic nervous system; CCK, cholecystokinin; FD, functional dyspepsia; GI, gastrointestinal; IBS, irritable bowel syndrome; IBS-C, constipation-predominant irritable bowel syndrome; IBS-D
Increased Prevalence of Rare Sucrase-isomaltase Pathogenic Variants in Irritable Bowel Syndrome Patients
Keywords: CADD; Combined Annotation Dependent Depletion; CSID; congenital sucrase-isomaltase deficiency; ExAC; Exome Aggregation Consortium; IBS; irritable bowel syndrome; IBS-C; IBS with constipation; IBS-D; IBS with diarrhea; M-CAP; Mendelian Clinically Applicabl
Association between SERT insertion/deletion polymorphism and the risk of irritable bowel syndrome: A meta-analysis based on 7039 subjects
Keywords: SERT; Serotonin transporter; IBS; Irritable bowel syndrome; IBS-D; Diarrhea predominant IBS; IBS-C; Constipation predominant IBS; IBS-M; Mixture of diarrhea and constipation IBS; HWE; Hardy-Weinberg equilibrium; NOS; Newcastle-Ottawa scale; Serotonin tran
Neuromodulators for Functional Gastrointestinal Disorders (Disorders of GutâBrain Interaction): A Rome Foundation Working Team Report
Keywords: Functional Gastrointestinal Disorders; Central Neuromodulators; Antidepressants; Antipsychotics; Disorders of Gut Brain Interaction; Chronic Abdominal Pain; CBT; cognitive behavioral therapy; CNS; central nervous system; CVS; cyclic vomiting syndrome; D2;
A Diet Low in FODMAPs Reduces Symptoms in Patients With Irritable Bowel Syndrome and A Probiotic Restores Bifidobacterium Species: A Randomized Controlled Trial
Keywords: Food Sensitivity; Fructans; Galacto-oligosaccharides; Lactose; CI; confidence interval; FODMAP; fermentable oligosaccharides, monosaccharides, disaccharides and polyols; GI; gastrointestinal; GSRS; Gastrointestinal Symptom Rating Scale; HRQOL; health-rela
Proteomics analysis of IBS-D with spleen and kidney yang deficiency
Keywords: Spleen and kidney yang deficiency; IBS-D; Proteomics; Mechanism;
A Diet Low in Fermentable Oligo-, Di-, and Monosaccharides and Polyols Improves Quality of Life and Reduces Activity Impairment in Patients With Irritable Bowel Syndrome and Diarrhea
Keywords: Nutrition; Functional Disorder; Psychology; Treatment; BMI; body mass index; CI; confidence interval; FODMAP; fermentable oligo-, di-, and monosaccharides and polyols; GI; gastrointestinal; HADS; Hospital Anxiety and Depression Scale; IBS; irritable bowel
2015 James W. Freston Single Topic Conference: A Renaissance in the Understanding and Management of Irritable Bowel Syndrome
Keywords: AGA; American Gastroenterological Association; BA; bile acid; EALs; early adverse life events; FGID; functional gastrointestinal disorder; IBS; irritable bowel syndrome; IBS-D; IBS with diarrhea; SCFA; short chain fact acid; TRPV; transient receptor poten
2015 James W. Freston Single Topic Conference: A Renaissance in the Understanding and Management of Irritable Bowel Syndrome
Keywords: AGA; American Gastroenterological Association; BA; bile acid; EALs; early adverse life events; FGID; functional gastrointestinal disorder; IBS; irritable bowel syndrome; IBS-D; IBS with diarrhea; SCFA; short chain fact acid; TRPV; transient receptor poten
Efficacy of a Gluten-Free Diet in Subjects With Irritable Bowel Syndrome-Diarrhea Unaware of Their HLA-DQ2/8 Genotype
Keywords: Clinical Trial; Gastrointestinal Symptoms; Food; Carbohydrates; CD; celiac disease; FIS; Fatigue Impact Scale; GFD; gluten-free diet; HADS; Hospital Anxiety and Depression Scale; IBS; irritable bowel syndrome; IBS-D; irritable bowel syndrome with diarrhea
MicroRNA 29 Targets Nuclear Factor-κB-Repressing Factor and Claudin 1 to Increase Intestinal Permeability
Keywords: Gene Regulation; mRNA Processing; Intestinal Barrier Function; Mouse Model; CLDN1; Claudin-1; IBS; irritable bowel syndrome; IBS-C; constipation-predominant irritable bowel syndrome; IBS-D; diarrhea-predominant irritable bowel syndrome; miRNA; microRNA; m
Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome
Keywords: Pain; Proteolytic Activity; Protease; PAR2; AA; arachidonic acid; CRD; colorectal distension; COX; cyclooxygenase; CYPe; cytochrome epoxygenase; DRG; dorsal root ganglia; EET; epoxyeicosatrienoic acid; FB; Fast Blue; HC; healthy control; HETE; hydroxyeico
A Diet Low in FODMAPs Reduces Symptoms of Irritable Bowel Syndrome
Keywords: Clinical Trial; Food Intolerance; Abdominal Pain; Short-Chain Carbohydrates; FODMAP; fermentable oligosaccharides, disaccharides, monosaccharides, and polyol; FWC; fecal water content; IBS; irritable bowel syndrome; IBS-C; constipation-predominant irritab
Original ResearchFull Report: Clinical-Alimentary TractRome III Functional Constipation and Irritable Bowel Syndrome With Constipation Are Similar Disorders Within a Spectrum of Sensitization, Regulated by Serotonin
Keywords: Visceral Sensitivity; 5-Hydroxytryptamine; 5-HT; Neurotransmitter; EC; enterochromaffin; FC; functional constipation; 5-HT; 5-hydroxytryptamine; HV; healthy volunteer; IBS-C; irritable bowel syndrome with constipation; IBS-D; irritable bowel syndrome with
Original ResearchFull Report: Clinical-Alimentary TractEluxadoline Benefits Patients With Irritable Bowel Syndrome With Diarrhea in a Phase 2 Study
Keywords: Clinical Trial; Functional Bowel Disorders; Transit; Drug; DOR; δ opioid receptor; EQ-5D; EuroQoL-5 Dimension; FDA; US Food and Drug Administration; GLMM; generalized linear mixed effects model; IBS; irritable bowel syndrome; IBS-D; irritable bowel syndr
A Controlled Trial of Gluten-Free Diet in Patients With Irritable Bowel Syndrome-Diarrhea: Effects on Bowel Frequency and Intestinal Function
Keywords: Permeability; Transit; Immunity; Cytokines; CI; confidence interval; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GCD; gluten-containing diet; G-CSF; granulocyte colony-stimulating factor; GFD; gluten-free diet; GM-CSF; granulocyte-macrophage colony
Identification of a dual δ OR antagonist/μ OR agonist as a potential therapeutic for diarrhea-predominant Irritable Bowel Syndrome (IBS-d)
Keywords: Mixed δ OR antagonist/μ OR agonist; Opioid receptor; Irritable Bowel Syndrome; IBS-d
Increased Risk of Miscarriage and Ectopic Pregnancy Among Women With Irritable Bowel Syndrome
Keywords: Abdominal Pain; Bloating; Intestinal; Pregnant; Complication; BMI; body mass index; CI; confidence interval; GPRD; General Practice Research Database; IBD; inflammatory bowel disease; IBS; irritable bowel syndrome; IBS-C; constipation-predominant irritabl
Increased Bile Acid Biosynthesis Is Associated With Irritable Bowel Syndrome With Diarrhea
Keywords: Colon; Malabsorption; Liver; Metabolism; BA; bile acid; BAM; bile acid malabsorption; BMI; body mass index; C4; 7α-hydroxy-4-cholesten-3-one; FGF; fibroblast growth factor; FGFR4; fibroblast growth factor receptor 4; HV; healthy volunteers; IBS; irritabl
Global Prevalence of and Risk Factors for Irritable Bowel Syndrome: A Meta-analysis
Keywords: Abdominal Pain; Bloating; Incidence; Rate; CI; confidence interval; GI; gastrointestinal; IBS; irritable bowel syndrome; IBS-C; constipation-predominant irritable bowel syndrome; IBS-D; diarrhea-predominant irritable bowel syndrome; IBS-M; mixed stool pat
Original ResearchBasic and Translational-Alimentary TractGlobal and Deep Molecular Analysis of Microbiota Signatures in Fecal Samples From Patients With Irritable Bowel Syndrome
Keywords: High-Throughput Analysis; Phylogenetic Microarray; Microflora; Enterotypes; HITChip; human intestinal tract chip; IBS; irritable bowel syndrome; IBS-C; constipation-predominant IBS; IBS-D; diarrhea-predominant IBS; IBS-A; alternating-type IBS; qPCR; quant
Impaired Uptake of Serotonin by Platelets From Patients With Irritable Bowel Syndrome Correlates With Duodenal Immune Activation
Keywords: Serotonin; Enteroendocrine; 5-Hydroxytryptamine Receptor; Neurotransmitter; CK20; cytokeratin 20; EC; enterochromaffin; 5-HT; 5-hydroxytryptamine; IBS-D; irritable bowel syndrome with diarrhea; IEL; intraepithelial lymphocyte; IL; interleukin; PBS-T; phos
Pharmacogenetic Trial of a Cannabinoid Agonist Shows Reduced Fasting Colonic Motility in Patients With Nonconstipated Irritable Bowel Syndrome
Keywords: Sensory; Motor; Clinical Trial; Drug Metabolism; FAAH; fatty acid amide hydrolase; IBS-A; irritable bowel syndrome alternating; IBS-C; irritable bowel syndrome with constipation; IBS-D; irritable bowel syndrome with diarrhea; MGLL; monoacylglycerol lipase
The Con Argument
Keywords: BAM; bile acid malabsorption; BM; bowel movements; FC; functional constipation; FDD; functional defecation disorders; FGID; functional gastrointestinal disorders; IBS; irritable bowel syndrome; IBS-C; irritable bowel syndrome with constipation; IBS-D; irr