دانلود مقالات ISI درباره Ick + ترجمه فارسی

سموم حیوانی برای درمان کانالوپاتی

Animal toxins for channelopathy treatment

Keywords: Channelopathy; Animal venom; Peptide toxin; Disease; Ligand-receptor interaction; Drug seeds; ASIC; acid-sensing ion channel; ATP; adenosine triphosphate; BK channel; big potassium channel; CFA; Freund's complete adjuvant; CFTR; cystic fibrosis transmembr

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

شیوع ناپایداری مایکاستالیته در نئوپلاسم های پوسچر پانکراس

Prevalence of Microsatellite Instability in Intraductal Papillary Mucinous Neoplasms of the Pancreas

Keywords: Pancreatic Cancer; Marker; T-cell Activation; Cytokine Production; dMMR; DNA mismatch repair; ICK; immune checkpoint; IHC; immunohistochemistry; IPMN; intraductal papillary mucinous neoplasm; MMR; mismatch repair; MSI; microsatellite instability; PCR; po

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

تعاملات جابجایی مونوکسیدکربن با کانالهای یونی و دو لایه لیپید: آیا پیچیدگی سهبعدی واقعی است؟

Gating modifier toxin interactions with ion channels and lipid bilayers: Is the trimolecular complex real?

Keywords: Disulfide-rich peptides; Model membranes; Pain; Rational drug design; Surface plasmon resonance; Sodium channel; Cryo-EM; cryo-electron microscopy; DOPG; 1,2-dioleoyl-sn-glycero-3-phosphoglycerol; DHPC; 1,2-diheptanoyl-sn-glycero-3-phosphocholine; GMT; ga

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2017 سفارش ترجمه

توکسین های وابسته به اتساع بر روی کانال های پتاسیم عصبی

Arthropod toxins acting on neuronal potassium channels

Keywords: Centipede; Honeybee; Neuronal potassium channel; Peptide; Scorpion; Spider; CNS; central nervous system; K+; potassium; Ca2+; calcium; Kv; voltage-gated potassium; KCa; calcium-activated potassium; Kir; inwardly rectifying potassium; K2P; two-pore potassi

دانلود رایگان متن کامل مقاله ISI 75 صفحه سال انتشار : 2017 سفارش ترجمه

ژن ها و تکامل سموم دو دامنه از زهر عنکبوت سیاه پوست

Genes and evolution of two-domain toxins from lynx spider venom

Keywords: gDNA; genomic DNA; ICK; inhibitor cystine knot; LRT; likelihood ratio test; ML; maximum likelihood; NG method; Nei-Gojobori method; PQM; processing quadruplet; RACE; rapid amplification of cDNA ends; Molecular evolution; Spider venom gland; Inhibitor cy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

CCRK is a novel signalling hub exploitable in cancer immunotherapy

Keywords: 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

KV1.2 channel-specific blocker from Mesobuthus eupeus scorpion venom: Structural basis of selectivity

Keywords: Ion channel; Molecular dynamics; Peptides; Potassium channel; Neurotoxin; Scorpion toxin; AgTx2; agitoxin-2; CaV; voltage-gated calcium channel; ChTx; charybdotoxin; CSα/β; cysteine-stabilized α/β motif; CSα/α; cysteine-stabilized α/α motif; CSTEV

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Discovery of two P-superfamily conotoxins, lt9a and lt9b, with different modifications on voltage-sensitive sodium channels

Keywords: Conus litteratus; P-superfamily conotoxin; Post-translational modification; Voltage-sensitive sodium channel; MALDI-TOF; matrix-assisted laser desorption/ionization-time-of-flight; γ-CRS; γ-carboxylation recognition signal sequence; ICK; inhibitory cy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7

Keywords: BSA; bovine serum albumin; CHOL; cholesterol; C1P; ceramide-1-phosphate; FLIPRTETRA; fluorescent imaging plate reader; GMT; gating modifier toxin; HBS; HEPES buffered saline; ICK; inhibitory cystine knot; LUV; large unilamellar vesicle; hNaV; human voltag

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

The expression and phylogenetics of the Inhibitor Cysteine Knot peptide OCLP1 in the honey bee Apis mellifera

Keywords: ATP; animal toxins and toxin-like peptides; HPG; hypopharingeal glands; ICK; Inhibitor Cysteine Knot; OCLP1; ω-conotoxin-like protein 1; PO; phenol oxidase; qRT-PCR; quantitative reverse transcription PCR; Apis mellifera; Cysteine-rich peptide; Toxin; An

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Huwentoxin-XVI, an analgesic, highly reversible mammalian N-type calcium channel antagonist from Chinese tarantula Ornithoctonus huwena

Keywords: HWTX-XVI; Tarantula toxin; N-type calcium channels; Dorsal root ganglia; Rat vas deferens; Pain model; Analgesic action; HWTX; Huwentoxin; ICK; inhibitor cystine knot; Cav channel; voltage-gated calcium channel; Nav channel; voltage-gated sodium channel;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Potency optimization of Huwentoxin-IV on hNav1.7: A neurotoxin TTX-S sodium-channel antagonist from the venom of the Chinese bird-eating spider Selenocosmia huwena

Keywords: ACF; animal-component free; BSA; bovine serum albumin; CaCl2; calcium chloride; CD; circular dichroism spectroscopy; CHO; Chinese hamster ovary; CNS; central nervous system; CO2; carbon dioxide; CsF; cesium fluoride; CsOH; cesium hydroxide; DIC; diisoprop

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Molecular determinants for the tarantula toxin jingzhaotoxin-I interacting with potassium channel Kv2.1

Keywords: Spider toxin; Kv2.1; Voltage-gated potassium channel; Mutation; JZTX; Jingzhaotoxin; ICK; Inhibitor Cystine Knot; MALDI-TOF; matrix assisted laser desorption/ionization time-of-flight; WT; Wide Type; NMR; nuclear magnetic resonance; IC50; median inhibitor

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Handling a tricycle: Orthogonal versus random oxidation of the tricyclic inhibitor cystine knotted peptide gurmarin

Keywords: 4-PDS; 4,4-dithiodipyridine; Acm; acetamidomethyl; DIPEA; diisopropylethylamine; DMSO; dimethylsulfoxide; EDT; ethanedithiol; ICK; inhibitor cystine knot; NMP; N-methylpyrrolidone; Pyr; pyroglutamic acid; StBu; tert-Butylthio; TFA; trifluoroacetic acid; T

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Solution structure of a short-chain insecticidal toxin LaIT1 from the venom of scorpion Liocheles australasiae

Keywords: ICK; inhibitory cystine knot; CSα/β; cystine-stabilized α-helix/β-sheet; Inhibitory cystine knot fold; LaIT1; Nuclear magnetic resonance; Scorpion toxin; Solution structure;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Overexpression of Arabidopsis ACK1 alters leaf morphology and retards growth and development

Keywords: CDK inhibitor; Transgenic Arabidopsis; ACK1; Plant growth; ICK; Leaf morphology;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2005 سفارش ترجمه

Heteropoda toxin 2 is a gating modifier toxin specific for voltage-gated K+ channels of the Kv4 family

Keywords: Ion channel gating; Potassium channel blockers; Potassium channels/drug effects; Recombinant fusion proteins; Potassium channels; Voltage-gated; Gating modifier toxins; Knottins; KCND; HpTx2; Heteropoda toxin 2; rHpTx2GS; recombinant HpTx2; ICK; inhibitor

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Discovery of an MIT-like atracotoxin family: Spider venom peptides that share sequence homology but not pharmacological properties with AVIT family proteins

Keywords: ACh; acetylcholine; ACTX; atracotoxin; BCA; bicinchoninic acid; Bv8; 8 kDa protein from the skin secretions of toads (Bombina variegata); CHO; Chinese hamster ovary; DDH; disulfide-directed β-hairpin; EST; expressed sequence tag; FLIPR; fluorometric ima

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه