Keywords: goat; growth hormone; growth hormone receptor; IGF-1; leptin and somatotrophic axis
مقالات ISI (ترجمه نشده)
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Keywords: Growth hormone deficiency; Pituitary dwarfism; IGF-1; Children; Hearing loss; Audiogram; Conductive hearing loss; Sensorineural hearing loss;
Insulin-like growth factor type I selectively binds to G-quadruplex structures
Keywords: DNA G-quadruplexes; Protein; IGF-1; Interaction; Quadruplex-ligands;
Characterization of insulin and IGF-1 receptor binding in equine liver and lamellar tissue: implications for endocrinopathic laminitis
Keywords: Horses; Hyperinsulinemia; IGF-1; Insulin; Laminitis; Receptors;
The effects of functionalized titanium with minTBP-1-IGF-1 for improving osteoblast activity
Keywords: IGF-1; Peptide aptamer; Surfaces; Osteoblast; Biomaterials;
High serum IGF-1 levels are associated with pregnancy loss following frozen-thawed euploid embryo transfer cycles
Keywords: IGF-1; insulin growth factor; IGFBP-1; IGF-binding protein 1; ICM; inner cell mass; N-FET; natural frozen-thawed euploid embryo transfer; BMI; body mass index; Insulin-like growth factor 1; IGF-1; Pregnancy loss; Euploid embryo transfer; Natural frozen-th
Shifting the IGF-axis: An age-related decline in human tear IGF-1 correlates with clinical signs of dry eye
Keywords: Tears; IGF-1; Dry eye; Aging;
Standardizing protocols dealing with growth hormone receptor gene disruption in mice using the Cre-lox system
Keywords: Growth hormone; GHRKO mice; GHRâ/â mice; iC-GHRKO; aGHRKO; Tamoxifen; Cre-lox; GH; growth hormone; GHR; growth hormone receptor; GHRKO; growth hormone receptor knockout; GHRâ/â; growth hormone receptor disrupted; IGF-1; insulin-like growth factor
Outcome of diabetes insipidus in patients with Rathke's cleft cysts
Keywords: ACTH; adrenocorticotropic hormone; DDAVP; 1-deamino-8-D-arginine vasopressin; DI; diabetes insipidus; FSH; follicle stimulating hormone; GH; growth hormone; GnRH; gonadotropin-releasing hormone; IGF-1; insulin-like growth factor-1; LH; luteinizing hormone
Bioavailable IGF-1 is beneficially associated with biomarkers of endothelial function in young healthy adults: The African-PREDICT study
Keywords: Vascular function; Youth; Age; Endothelial activation; Insulin-like growth factor-1; Insulin-like growth factor-binding protein-3; von Willebrand factor; Intercellular adhesion molecule-1; Vascular cell adhesion molecule-1; ABPM; ambulatory blood pressure
IGF-1 defends against chronic-stress induced depression in rat models of chronic unpredictable mild stress through the PI3K/Akt/FoxO3a pathway
Keywords: IGF-1; Chronic-stress induced depression; Rat models; Chronic unpredictable mild stress; PI3K/Akt/FoxO3a signaling pathway;
IGF-1 resist oxidative damage to HaCaT and depigmentation in mice treated with H2O2
Keywords: Vitiligo; IGF-1; Immunosuppressive; CD8+ T cells; H2O2;
Quantification of specific growth patterns and frequency of the empty sella phenomenon in growth hormone-secreting pituitary adenomas
Keywords: ACTH; Adrenocorticotropic hormone; AUC; Area under curve; ES; Empty sella; GH; Growth hormone; ICC; Intra-class correlation coefficient; IGF-1; Insulin-like growth factor 1; ISE; Intrasellar extension; ISR; Inferior-superior tissue ratio; PRL; Prolactin;
Sinonasal outcome after endoscopic mononostril transsphenoidal surgery: A single center cohort study
Keywords: ACTH; adrenocorticotropic hormone; AIDA; Advanced Image and Data Acquisition; CSF; cerebrospinal fluid; CT; computer tomography; ENT; ear, nose, throat; FSH; follicle stimulating hormone; GH; growth hormone; GTR; gross-total resection; ICA; internal carot
Treatment targets for M2 microglia polarization in ischemic stroke
Keywords: PACAP; pituitary adenylate cyclase-activating polypeptide; OGA; beta-N-acetylglucosaminidase; FAM19A3; TAFA3, TAFA family (TAFA1-5); TPA; tissue plasminogen activator; GSH; glutathione-SH; NGF; nerve growth factor; BCL-2/BCL-X1; B cell leukemia/lymphoma
MicRNA-320 facilitates the brain parenchyma injury via regulating IGF-1 during cerebral I/R injury in mice
Keywords: miR-320; IGF-1; Ischemia/reperfusion; Apoptosis;
Increased fibrosis: A novel means by which GH influences white adipose tissue function
Keywords: GH; growth hormone; GHR; growth hormone receptor; GHRKO; growth hormone receptor knockout; FaGHRKO; fat growth hormone receptor knockout; LiGHRKO; liver growth hormone receptor knockout; IGF-1; insulin-like growth factor 1; WAT; white adipose tissue; ECM;
Effects of dietary supplementation with alfalfa (Medicago sativa L.) saponins on lamb growth performance, nutrient digestibility, and plasma parameters
Keywords: ADG; average daily gain; ADF; acid detergent fiber without a heat stable amylase and expressed inclusive the residual ash; AS; alfalfa saponins; ALT; alanine transaminase; AST; aspartate transaminase; BLI; body length index; BUN; blood urea nitrogen; DMI;
The physiopathologic interplay between stem cells and tissue niche in muscle regeneration and the role of IL-6 on muscle homeostasis and diseases
Keywords: IL-; interleukin; SC; satellite cell; ECM; extracellular matrix; MuSCs; muscle stem cells; ROS; reactive oxygen species; Treg; regulatory T cells; Pax7; Paired box protein 7; Myf5; myogenic factor 5; MyoD; myoblast determination protein; MRF; muscle regul
Impairment of Akt activity by CYP2E1 mediated oxidative stress is involved in chronic ethanol-induced fatty liver
Keywords: AFL; alcoholic fatty liver; ALD; alcoholic liver disease; ALT; alanine transaminase; AMPK; AMP-activated protein kinase; AST; aspartate transaminase; CMZ; chlormethiazole; CYP2E1; cytochrome P4502E1; 4-HNE; 4-hydroxynonenal; IGF-1; insulin-like growth fac
TNF-α and IGF-1 differentially modulate ionizing radiation responses of lung cancer cell lines
Keywords: TNF-α; IGF-1; Ionizing radiation; MAPK; Mitotic index;
Interaction of Abl Tyrosine Kinases with SOCS3 Impairs Its Suppressor Function in Tumorigenesis
Keywords: CML; chronic myeloid leukemia; EGFR; Epidermal growth factor receptor; FUS1; Fused in sarcoma-1; GST; Glutathione S-transferase; IGF-1; Insulin-like growth factor-1; JAK/STAT; Janus tyrosine kinase/signal transducer and activator of transcription; MMP-1;
GH directly stimulates UCP3 expression
Keywords: aSTAT5B; constitutively active STAT5B; ANOVA; analysis of variance; BLAST; Basic Local Alignment Search Tool; DMEM; Dulbecco's Modified Eagle's Medium; GAS; interferon-gamma activated sequence; GH; growth hormone; GHR; growth hormone receptor; IGF-1; insu
Repurposing of sodium valproate in colon cancer associated with diabetes mellitus: Role of HDAC inhibition
Keywords: ACF; aberrant crypt foci; ALP; alkaline phosphatase; ANOVA; one-way analysis of variance; CEA; carcinogenic embryonic antigen; DMH; 1,2 dimethylhydrazine; EDTA; ethylene diamine tetra acetic acid; ELISA; enzyme-linked immunosorbent assay; HbA1c; glycosyla
MicroRNA-30a-3p is overexpressed in the placentas of patients with preeclampsia and affects trophoblast invasion and apoptosis by its effects on IGF-1
Keywords: apoptosis; epigenetics; functional assays; IGF-1; invasion; microRNA; preeclampsia; placenta; trophoblast;
Scutellaria: Debates on the anticancer property
Keywords: Bcl-2; B-cell lymphoma 2; 5-FU; 5-Fluorouracil; TGF-β1; transforming growth factor beta 1; PTEN; phosphatase and tensin homolog; HIF-1α; hypoxia-inducible factor 1-alpha; MAPK; mitogen-activated protein kinase; CRC; cyclic redundancy check; SHH; sonic h
Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes
Keywords: Primary astrocytes; IGF-1; Amyloid; Mitochondria; ROS; Alzheimer's disease;
Glucagon and/or IGF-1 Production Regulates Resetting of the Liver Circadian Clock in Response to a Protein or Amino Acid-only Diet
Keywords: Circadian rhythm; Food resetting; Protein; Amino acid; Glucagon; IGF-1;
Novel pathogenic RECQL4 variants in Chinese patients with Rothmund-Thomson syndrome
Keywords: RTS; Rothmund-Thomson syndrome; RECQL4; RecQ-like DNA helicase type 4; NGS; next-generation sequencing; RAPADILINO; RAdial hypoplasia, PAtellar hypoplasia and cleft or arched PAlate, DIarrhoea and DIslocated joints, LIttle size and LIimb malformation, sle
Loss of histone deacetylase 2 inhibits oxidative stress induced by high glucose via the HO-1/SIRT1 pathway in endothelial progenitor cells
Keywords: DFU; diabetic foot ulcer; EPC; endothelial progenitor cells; HDAC2; histone deacetylase 2; ROS; reactive oxygen species; HO-1; home oxygenase; VEGF; vascular endothelial growth factor; IGF-1; insulin-like growth factor-1; FBS; fetal bovine serum; Diabetic
Diabetes mellitus and Alzheimer's disease: GSK-3β as a potential link
Keywords: 3xTg; triple-transgenic; Aβ; β-amyloid; AD; Alzheimer's disease; ADAS-cog; Alzheimer's Disease Assessment Scale-cognitive subscale; Akt; protein kinase B; APP; amyloid precursor protein; CREB; cAMP-response element binding protein; DM; diabetes mell
Coronary microvascular dysfunction may be related to IGF-1 in acromegalic patients and can be restored by therapy
Keywords: IGF-1; Microvascular dysfunction; Coronary flow reserve; Acromegaly; GH;
Hepatitis B virus suppresses the secretion of insulin-like growth factor binding protein 1 to facilitate anti-apoptotic IGF-1 effects in HepG2 cells
Keywords: CHB; chronic hepatitis B; HBV; hepatitis B virus; HBx; HBV X protein; HCC; hepatocellular carcinoma; IGF-1; insulin-like growth factor 1; IGFBP1; insulin-like growth factor binding protein 1; STS; staurosporine; TG; thapsigargin; HBs; viral surface protei
The association between peripheral total IGF-1, IGFBP-3, and IGF-1/IGFBP-3 and functional and cognitive outcomes in the Mayo Clinic Study of Aging
Keywords: IGF-1; Function; Cognition; Aging;
Bone resorption deficiency affects tooth root development in RANKL mutant mice due to attenuated IGF-1 signaling in radicular odontoblasts
Keywords: RANKL; receptor activator of NF-κB ligand; IGF-1; insulin-like growth factor-1; Nfic; nuclear factor I C; DECM; dentin extracellular matrix; HERS; Hertwig's epithelial root sheath; PCNA; proliferating cell nuclear antigen; BRCM; bone resorption-condition
Antidepressant-like effects of insulin and IGF-1 are mediated by IGF-1 receptors in the brain
Keywords: Insulin; IGF-1; JB-1; Depression; Diabetes; Porsolt Forced Swim Test;
The interaction of IGF-1/IGF-1R and hydrogen sulfide on the proliferation of mouse primary vascular smooth muscle cells
Keywords: BrdU; bromodeoxyuridine; CBS; cystathionine-beta-synthase; CRISPR; clustered regularly interspaced short palindromic repeats; CSE; cystathionine-gamma-lyase; DMEM; dulbecco's modified eagle's medium; ERK; extracellular regulated protein kinase; FBS; f
Effect of protein restriction of bovine dams during late gestation on offspring postnatal growth, glucose-insulin metabolism and IGF-1 concentration
Keywords: Gestation; Undernutrition; Postnatal growth; Glucose metabolism; IGF-1;
Stimulation of liver IGF-1 expression promotes peak bone mass achievement in growing rats: a study with pomegranate seed oil
Keywords: PSO; pomegranate seed oil; PBM; peak bone mass; BMD; bone mineral density; HDAC; histones deacetylases; IGF-1; insulin growth factor-1; IRS; insulin receptor substrate; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; CH
The longevity gene INDY (I'm Not Dead Yet) in metabolic control: Potential as pharmacological target
Keywords: Aak2; 5â²AMP-activated protein kinase catalytic subunit alpha-2; ACC; acetyl CoA carboxylase; Acly; ATP citrate lyase; Adipo-IR; adipose tissue insulin resistance index; ADME; absorption, distribution, metabolism, excretion; AGA; appropriate-for-gestatio
Impaired Neuronal Differentiation of Neural Stem Cells Lacking the Engrailed-2 Gene
Keywords: ANOVA; analysis of variance; ASD; autism spectrum disorders; BDNF; brain-derived neurotrophic factor; d; days in vitro; E; embryonic day; En; engrailed; EthD-1; ethidium homodimer-1; FMRP; Fragile-X mental retardation protein; GABA; γ-aminobutyric acid;
Neuroprotective effect of He-Ying-Qing-Re formula on retinal ganglion cell in diabetic retinopathy
Keywords: HF; He-Ying-Qing-Re Formula; RGC; Retinal ganglion cell; DR; Diabetic retinopathy; STZ; Streptozotocin; GCL; Ganglion cell layer; INL; Inner nuclear layer; IPL; Inner plexiform layer; H2O2; Hydrogen peroxide; ROS; Reactive oxygen species; BRB; Blood-retin
Glutamatergic nervous system degeneration in a C. elegans TauA152T tauopathy model involves pathways of excitotoxicity and Ca2+ dysregulation
Keywords: Alzheimer disease (AD); Frontotemporal dementia (FTD); Tau pathology; Calreticulin; Caspase; Cathepsin; Necrosis; Insulin-signaling; 2N4R-Tau; largest isoform of human Tau in CNS (441 residues 2 inserts +4 repeats) accession: NP_005901.2 amino acid number
Cancer-associated fibroblasts promote epithelial-mesenchymal transition and EGFR-TKI resistance of non-small cell lung cancers via HGF/IGF-1/ANXA2 signaling
Keywords: Cancer-associated fibroblasts; Epithelial-mesenchymal transition; EGFR-TKIs resistance; HGF; IGF-1; Annexin A2;
Chronic heat stress increases insulin-like growth factor-1(IGF-1) but does not affect IGF-binding proteins in growing pigs
Keywords: Chronic heat stress; IGF-1; IGFBPs; Growing pigs;
Regulation of the activins-follistatins-inhibins axis by energy status: Impact on reproductive function
Keywords: AFI; Activin-follistatin-inhibin system; AMH; Anti-MÏllerian Hormone; BMI; Body mass index; FSH; Follicle-stimulating hormone; FSTL3; Follistatin-like 3; GCRC; General Clinical Research Center; HA; Hypothalamic Amenorrhea; HPG-axis; Hypothalamic-pituitar
Nanomedicine for the cardiac myocyte: Where are we?
Keywords: 7KC; 7-ketocholesterol; Ang II; Angiotensin II; AT1; Angiotensin II type 1; AT1R; Ang II type 1 receptor; Au; Gold; BIO; 6-Bromoindirubin-3 oxine.; CeO2; Cerium oxide/ceria; CLIO; Cross-linked iron oxide; CNF; Carbon nanofiber; CNT; Carbon nanotube; CsA;
Glucose dependent miR-451a expression contributes to parathyroid hormone mediated osteoblast differentiation
Keywords: Ovx; Ovariectomy; PTH; Parathyroid Hormone; miRNA; MicroRNA; μCT; Micro-computed tomography; BMD; Bone mineral density; BV/TV; Bone volume/Total volume; SMI; Structural model index; Tb.N; Trabecular number; Conn Dn; Connection density; Tb.Sp; trabecular
Insulin-like Growth Factor 1 (IGF-1) as a marker of cognitive decline in normal ageing: A review
Keywords: IGF-1; Insulin-like Growth Factor; Ageing; Cognition; Cognitive Impairment; Dementia; Growth Hormone; Neurogenesis; Cognitive Decline; Elderly; MCI;
Ethnopharmacological uses, phytochemistry, biological activities, and therapeutic applications of Alpinia oxyphylla Miquel: A review
Keywords: AD; Alzheimer's disease; AcOEt; Ethyl acetate; AOE; Ethanolic extract of the fruit of A. oxyphylla; AOF; Alpinia oxyphylla fruit; BBB; Blood-brain barrier; CAT; Catalase; CCl4; Carbon tetrachloride; CKD; Chronic kidney disease; EA portion; Ethyl acetate-s