Expression of the insulin-like growth factor and insulin systems in the luteinizing macaque ovarian follicle
Keywords: Luteinization; granulosa cell; IGF; IGFBP; primate
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The Growth Hormone-Insulin-like Growth Factor Axis in Glycogen Storage Disease Type 1: Evidence of Different Growth Patterns and Insulin-like Growth Factor Levels in Patients with Glycogen Storage Disease Type 1a and 1b
Keywords: AHA; Anti-hypothalamus antibodies; ALS; Acid labile subunit; APA; Anti-pituitary antibodies; BMI; Body mass index; G6Pase; Microsomal glucose-6-phosphatase; G6Paseα; G6Pase alpha; G6PT; G6P translocase; GH; Growth hormone; GSD1; Glycogen storage disease
Novel modulators of senescence, aging, and longevity: Small non-coding RNAs enter the stage
Keywords: Aging; Senescence; Small non-coding RNA; ncRNA; miRNA; qiRNA; IGF; TOR
Zinc deficiency suppresses matrix mineralization and retards osteogenesis transiently with catch-up possibly through Runx 2 modulation
Keywords: ALP; alkaline phosphatase; ANOVA; analysis of variance; ECM; extracellular matrix; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; HSD; Tukey's honestly significant difference; IGF; insulin-like growth factor-I; IL-6; interleukin-6; OC; osteocalcin; OPN;
Nutrient intake in the bovine during early and mid-gestation causes sex-specific changes in progeny plasma IGF-I, liveweight, height and carcass traits
Keywords: Cattle; Fetal programming; IGF; Maternal nutrition; Metabolites; Postnatal growth
Research ArticleIGF activation in a molecular subclass of hepatocellular carcinoma and pre-clinical efficacy of IGF-1R blockage
Keywords: HCC; hepatocellular carcinoma; IGF; insulin-like growth factor; IGFBP-3; IGF binding protein 3; HCV; hepatitis C virus; FBS; fetal bovine serum; RT-PCR; real time polymerase chain reaction; miR-; microRNA; GSEA; gene set enrichment analysis; RPS6; ribosom
Research ReportA neuroimaging investigation of the association between aerobic fitness, hippocampal volume, and memory performance in preadolescent children
Keywords: ADHD; attention-deficit hyperactivity disorder; BDNF; brain-derived neurotrophic factor; dâ²; d prime; FIRST; FMRIB's Integrated Registration and Segmentation Tool; IGF; insulin-like growth factor; IQ; intelligence quotient; K-BIT; Kaufman Brief Intellig
Clinical Advances in Liver, Pancreas, and Biliary TractInsulin-Like Growth Factor Axis Gene Polymorphisms and Clinical Outcomes in Pancreatic Cancer
Keywords: Pancreatic Cancer; Insulin-Like Growth Factor-Axis; Single-Nucleotide Polymorphism; Overall Survival; AKT; v-akt murine thymoma viral oncogene homolog; ERK; extracellular signal-regulated kinase; FDR; false discovery rate; IGF; insulin-like growth facto
ADAM12 is expressed by astrocytes during experimental demyelination
Keywords: ADAM; a disintegrin and metalloproteinase; APC; adenomatous polyposis coli; AT; annealing temperature; bFGF; basic fibroblast growth factor; BP; base pairs; BSA; bovine serum albumine; CC; corpus callosum; CNS; central nervous system; Cx; cortex; ctrl; co
Primary Prevention of Colorectal Cancer
Keywords: Colorectal Cancer; Diet; Lifestyle; Epidemiology; BMI; body mass index; CI; confidence interval; COX-2; cyclooxygenase-2; DFMO; difluoromethylornitine; EPIC; European Prospective Investigation into Cancer and Nutrition; HbA1c; glycosylated hemoglobin; HPF
Polymeric materials for bone and cartilage repair
Keywords: ALP; alkaline phosphatase; BAGs; bioactive glasses; BC; bacterial cellulose; BMPs; bone morphogenetic proteins; CAD; computer assisted design; Dex-HEMA; hydroxyethyl methacrylated dextran; Dex-MA; methacrylated dextran; ECM; extracellular matrix; FGF; fib
Retrospective Study of the Potential Benefits and Adverse Events during Growth Hormone Treatment in Children with Prader-Willi Syndrome
Keywords: BMI; Body mass index; GH; Growth hormone; HV; Height velocity; IGF; Insulin-like growth factor; LBM; Lean body mass; OSA; Obstructive sleep apnea; PWS; Prader-Willi syndrome; RCT; Randomized controlled trial; SDS; Standard deviation score;
BMS-536924 sensitizes human epithelial ovarian cancer cells to the PARP inhibitor, 3-aminobenzamide
Keywords: Epithelial ovarian cancer; Insulin-like growth factor inhibitor; IGF; PARP inhibitor
Regulatory effects of biomechanical strain on the insulin-like growth factor system in human periodontal cells
Keywords: IGF; PDL; Periodontal; Biomechanical strain; Tension
Ovarian function of the trout preovulatory ovary: New insights from recent gene expression studies
Keywords: Developmental competence; Estradiol; Follicle; Growth factors; IGF; Maturational competence; Oocyte; SHBG
Expression of growth-related genes in muscle during fasting and refeeding of juvenile Atlantic halibut, Hippoglossushippoglossus L.
Keywords: Atlantic halibut; Cathepsin; Fasting; Refeeding; Reference gene; IGF
Validation of immature adipogenic status and identification of prognostic biomarkers in myxoid liposarcoma using tissue microarrays
Keywords: Liposarcoma; Tissue microarray; RET; IGF
Type 2 diabetic mice demonstrate slender long bones with increased fragility secondary to increased osteoclastogenesis
Keywords: 8-OHdG; 8-hydroxydeoxyguanosine, an oxidized nucleoside of DNA; αMEM; α-modified minimum essential medium; AGE; advanced glycation end products; BMD; areal bone mineral density measured by DEXA; DEXA; dual energy X-ray absorptiometry; FVB/N; Friend viru
C-peptide of preproinsulin-like peptide 7: Localization in the rat brain and activity in vitro
Keywords: Calcium imaging; immunohistochemistry; nucleus incertus; hypothalamus; [Ca2+]i; cytosolic calcium concentrations; C-INSL7; C-peptide of human preproinsulin-like peptide 7; DiSBAC4(3); bis-[1,3-dibutylbarbituric acid] trimethineoxonol; HBSS; Hanks' balance
Adiposity and TV Viewing Are Related to Less Bone Accrual in Young Children
Keywords: BMC; Bone mineral content/bone mass; BMI; Body mass index; DXA; Dual energy x-ray absorptiometry; GH; Growth hormone; IGF; Insulin-like growth factor; pQCT; Peripheral quantitative computed tomography;
Expression of IGF receptors and its ligands in bovine oocytes and preimplantation embryos
Keywords: Oocyte; Preimplantation embryo; In vitro; IGF; Bovine
Bone marrow cell-induced protection of the human myocardium: Characterization and mechanism of action
Keywords: 17; 29; 31; BMC; bone marrow cell; CK; creatine kinase; DAPI; 4â²6-diamidino-2-phenylindole; ELISA; enzyme-linked immunosorbent assay; IGF; insulin-like growth factor; IGF-1R; insulin-like growth factor-1 receptor; IP; ischemic preconditioning; I/R; isch
Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma
Keywords: HCC; hepatocellular carcinoma; SREBF1; sterol regulatory element binding factor 1; HBV; hepatitis B virus; HCV; hepatitis C virus; SAGE; serial analysis of gene expression; RT-PCR; reverse transcription-polymerase chain reaction; IHC; immunohistochemistry
Early pregnancy alters the metabolic responses to restricted nutrition in sheep
Keywords: Sheep; Undernutrition; Early pregnancy; GHR; IGF; Leptin
Type I Insulin-like Growth Factor Receptor Induces Pulmonary Tumorigenesis
Keywords: AAH; adenomatous alveolar hyperplasia; BASC; bronchioalveolar stem cell; CREB; cyclic adenosine monophosphate response element binding protein; CCSP; Clara cell secretory protein; IGF; insulin-like growth factor; IGFBP; insulin-like growth factor binding
Regulation of growth hormone receptors in human prostate cancer cell lines
Keywords: Growth hormone receptors; Prostate cancer cell lines (human); Androgens; Oestrogens; Thyroid hormone; IGF
The potential role of green tea catechins in the prevention of the metabolic syndrome - A review
Keywords: BMI; body mass index; COMT; catechol-O-methyl-transferase; EC; (â)-epicatechin; ECG; (â)-epicatechin-3-gallate; EGC; (â)-epigallocatechin; EGCG; (â)-epigallocatechin-3-gallate; HDL; high density lipoprotein; IDF; International Diabetes Federation;
Targeted therapies in the treatment of advanced/metastatic NSCLC
Keywords: NSCLC; Targeted therapies; EGFR; VEGF; Tyrosine kinase inhibitors; IGF; m-TOR; Proteasome; HDAC
Over Expression of Insulin-Like Growth Factor Binding Protein 3 in Clear Cell Renal Cell Carcinoma
Keywords: kidney; carcinoma; renal cell; insulin-like growth factor binding protein 3; microarray analysis; tumor markers; biological; IGF; insulin-like growth factor; IGFBP; insulin-like growth factor binding protein; RCC; renal cell carcinoma;
Commonalities in the endocrinology of stem cell biology and organ regeneration
Keywords: PTH; parathyroid hormone; HSC; haematopoietic stem cell; IGF; insulin-like growth factor; PTHrP; PTH-related peptide; FGF; fibroblast growth factor; ESC; embryonic stem cell; GLP; glucagon-like peptide; T3; triiodothyronine; TR; thyroid hormone receptor;
Differential effects of human chorionic gonadotropin and decidualization on insulin-like growth factors-I and -II in human endometrial stromal cells
Keywords: Endometrium; decidualization; implantation; hCG; IGF
Assessing the potential usefulness of IGF-related peptides and adiponectin for predicting disease risk
Keywords: Insulin-like growth factor; IGF; IGFBP; Adiponectin; Colorectal cancer; Biomarkers; Intra-individual; Inter-individual; Variation
Identification of phylogenetically conserved enhancer elements implicated in pancreas development in the WISP1 and CTGF orthologs
Keywords: TFBS; transcription factor binding site; CTGF; connective tissue growth factor; ESC; embryonic stem cell; RT-PCR; reverse transcription polymerase chain reaction; EST; expressed sequence tag; IGF; insulin-like growth factor; TSS; transcription starting si
Frailty and Its Potential Relevance to Cardiovascular Care
Keywords: ADL; activities of daily living; CAD; coronary artery disease; CHS; Cardiovascular Health Study; CRP; C-reactive protein; IGF; insulinlike growth factor; LASA; Longitudinal Aging Study Amsterdam;
Dehydroepiandrosterone Replacement Therapy in Hypoadrenal Women: Protein Anabolism and Skeletal Muscle Function
Keywords: COX; cytochrome c oxidase; DHEA; dehydroepiandrosterone; DHEA-S; DHEA sulfate; FFM; fat-free mass; FSR; fractional synthesis rate; [2H4]; [ring 2,3,5,6-2H4]; IGF; insulinlike growth factor; IGFBP; IGF binding protein; MYH; myosin heavy chain; mRNA; messen
IGF-I binding to the IGF-I receptor is affected by contaminants in commercial BSA: The contaminants are proteins with IGF-I binding properties
Keywords: IGF; Receptor; Binding affinity; Insulin; Albumin; BSA; Hybrid receptor binding
Survival and cellular immune functions in septic mice treated with growth hormone (GH) and insulin-like growth factor-I (IGF-I)
Keywords: IGF; Growth hormone; Sepsis; Immune function; Mouse
IGFBP-3 sensitizes prostate cancer cells to interferon-gamma-induced apoptosis
Keywords: IGF; insulin-like growth factor; IGFBP-3; insulin-like growth factor binding protein-3; rhIGFBP-3; recombinant human IGFBP-3; IFN-γ; interferon-gamma; IFN-α; interferon-alpha; IFN-β; interferon-beta; JAK; Janus kinase; STAT; signal transducers and acti
Receptor interactions by polybrominated diphenyl ethers versus polychlorinated biphenyls: A theoretical structure–activity assessment
Keywords: Polybrominated diphenyl ethers; PBDEs; Polychlorinated biphenyls; PCBs; AhR; CAR; PXR; ER; AR; PR; DHT; TH; T3; T4; IGF; PPAR; RyR; GR; GABA; Conformation; Constitution; Binding affinity; Polarizability; Hydrophilicity; Gibbs free solvation energy; Induct
Evaluation of the cancer chemopreventive efficacy of silibinin in genetic mouse models of prostate and intestinal carcinogenesis: Relationship with silibinin levels
Keywords: Chemoprevention; Preclinical models; Silibinin; IGF
βγ subunits of Gi/o suppress EGF-induced ERK5 phosphorylation, whereas ERK1/2 phosphorylation is enhanced
Keywords: BDNF; brain-derived neurotrophic factor; CTX; cholera toxin; DMEM; Dulbecco's modified Eagle's medium; EGF; epidermal growth factor; EPAC; exchange protein activated by cAMP; ERK; extracellular signal-regulated kinase; GPCR; G-protein-coupled receptor; G3
Regulation of Akt during hibernation in Richardson's ground squirrels
Keywords: PKA; cAMP-dependent protein kinase A; PKC; Ca2+-activated, phospholipid-dependent protein kinase C; GSK; glycogen synthase kinase; PP; protein phosphatase; PMSF; phenylmethylsulfonyl fluoride; DTT; dithiothreitol; IGF; insulin-like growth factor; PH; plec
Insulin signaling pathways and cardiac growth
Keywords: Insulin; IGF; Cardiac growth; Signal transduction; Signaling; Diabetes; Diabetic cardiomyopathy; Heart failure; Hypertrophy
Growth factor contents of autologous human sera prepared by different production methods and their biological effects on chondrocytes
Keywords: Autologous serum; Chondrocytes; Cartilage tissue engineering; Proliferation; Differentiation; ACI; autologous chondrocyte implantation; BMP-2; bone morphogenetic protein-2; WBS; whole blood-derived serum; PCS; platelet-containing plasma-derived serum; PDS
Dexamethasone and GLP-2 administered to rat dams during pregnancy and lactation have late effects on intestinal sugar transport in their postweanling offspring
Keywords: Akt/PKB; Protein kinase B; BBM; brush border membrane; BLM; basolateral membrane; DEX; dexamethasone; EGF; epidermal growth factor; GC; glucocorticosteroids; GLP-2; glucagon-like peptide-2; GLUT; glucose transporter; GSK-3; glycogen synthase kinase 3; IGF
Endometrial expression of the insulin-like growth factor system during uterine involution in the postpartum dairy cow
Keywords: Bovine; Uterus; IGF; IGFBP; Involution;
Interrelationships between negative energy balance (NEB) and IGF regulation in liver of lactating dairy cows
Keywords: Bovine; IGF; IGFBP; Lactation; Energy
Modulating peripheral gonadotrophin levels affects follicular expression of mRNAs encoding insulin-like growth factors and receptors in sheep
Keywords: Follicle; FSH; LH; IGF; GnRH antagonist; Bovine follicular fluid
NF-κB Activates Transcription of the RNA-Binding Factor HuR, via PI3K-AKT Signaling, to Promote Gastric Tumorigenesis
Keywords: ARE; adenylate uridylate-rich elements; FBS; fetal bovine serum; 5-FU; 5-fluorouracil; IGF; insulin-like growth factor; NF-κB; nuclear factor-κB; PI3K; phosphatidylinositol 3-kinase; PCR; polymerase chain reaction; RT; reverse transcription; siRNA; sh
Malignant Melanoma in the 21st Century: The Emerging Molecular Landscape
Keywords: CDK; cyclin-dependent kinase; CGH; comparative genomic hybridization; EDN; endothelin; ERK; extracellular signal-regulated kinase; FGF; fibroblast growth factor; HGF; hepatocyte growth factor; IGF; insulinlike growth factor; MAPK; mitogen-activated protei