دانلود مقالات ISI درباره Il-2 + ترجمه فارسی

روش های درمانی نانو متخصص برای غلبه بر مقاومت به دارو سرطان

Nanomedicine therapeutic approaches to overcome cancer drug resistance

Keywords: AML; acute myeloid leukemia; CAM-DR; cell adhesion-mediated drug resistance; CCP; charge-conversion polymer; CLL; chronic lymphocytic leukemia; CNS; central nervous system; CSC; cancer stem cell; EGFR; epidermal growth factor receptor; EPR; enhanced perme

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

مدلسازی ایمونوتراپی مبتنی بر اینترلوکین-2 در پاتوژنز ایدز

Modeling interleukin-2-based immunotherapy in AIDS pathogenesis

Keywords: AICD; activation-induced cell death; AIDS; acquired immunodeficiency syndrome; APC; antigen presenting cells; CCF; cell-cell fusion; CNS; central nervous system compartment; DAE; differential-algebraic equations; ENV; Env-CD4 cross-linking mediated apop

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2013 سفارش ترجمه

غربالگری Phytochemical از عصاره dichloromethane-ethanolic از Eriosema campestre var. ریشه های ماکروفیلوم و اثر ضد انعقادی آن بر لنفوسیت های خون محیطی انسانی

Phytochemical screening of the dichloromethane–ethanolic extract of Eriosema campestre var. macrophylum roots and its antiproliferative effect on human peripheral blood lymphocytes

Keywords: Eriosema campestre; Flavonoids; Cellular proliferation; IL-2

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

واکسن های سرطانی مبتنی بر سلول های اصلاح کننده درمان شده

Therapeutic gene modified cell based cancer vaccines

Keywords: AAV; adeno-associated viruses; Ad6; adenovirus serotype 6; ABCB5 +; ATP-binding cassette sub-family B member 5; ALDH; aldehyde dehydrogenase; AML; acute myeloid leukemia; APCs; antigen presenting cells; B7.1; (CD80) cluster of differentiation 80; BCG; Ba

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

IL-2-induced NF-κB phosphorylation upregulates cation nonselective conductance in human cardiac fibroblasts

Keywords: Human cardiac fibroblasts; Cation nonselective conductance; IL-2; PKC; NF-κB and IκB;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Guanine and inosine nucleotides/nucleosides suppress murine T cell activation

Keywords: T cell; IL-2; Purine nucleotide; GTP; ITP; Purinergic receptor; ConA; concanavalin A; ERK; extracellular signal-regulated kinase; IL; interleukin; LDH; lactate dehydrogenase; MAPK; mitogen-activated protein kinase; mAb; monoclonal antibody; TCR; T cell re

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Short-term culture with IL-2 is beneficial for potent memory chimeric antigen receptor T cell production

Keywords: IL-2; Chimeric antigen receptor; Memory T cell;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

Ox40 regulates the conversion and suppressive function of double-negative regulatory T cells

Keywords: Tregs; regulatory T cells; DNT; double-negative regulatory T cells; mDCs; mature dendritic cells; KO; knockout; WT; wild type; Ox40-KO; Ox40 knockout; IL-2; interleukin 2; GM-CSF; granulocyte macrophage colony stimulating factor; CM; complete culture medi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Synergistic therapeutic effect of diethylstilbestrol and CX-4945 in human acute T-lymphocytic leukemia cells

Keywords: DES; T-ALL; Jurkat; IL-2; CK2; NF-κB;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Enhanced perforin expression associated with dasatinib therapy in natural killer cells

Keywords: Dasatinib; JAK; STAT; Perforin; Interferon-γ; IL-2;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Alcohol-soluble polysaccharide from Astragalus membranaceus: Preparation, characteristics and antitumor activity

Keywords: ASP; alcohol-soluble polysaccharide from Astragalus membranaceus; HPGPC; high-performance gel permeation chromatography; FTIR; Fourier transform infrared spectroscopy; IC; ion chromatography; H22; murine hepatocarcinoma cells; 5-Fu; 5-fluorouracil; NK; na

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Fine tuning subsets of CD4+ T cells by low-dosage of IL-2 and a new therapeutic strategy for autoimmune diseases

Keywords: aa; Amino acids; A region; Acidic region of IL-2Rβ; AKT; Protein kinase B; AA; Alopecia Areata; CTLA-4; Cytotoxic T lymphocyte antigen-4; cDNA; Complementary DNA; Foxp3; Forkhead box P3; GVHD; Chronic graft-versus-host disease; HCV; Hepatitis C virus; hd

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

In vitro combinatorial anti-proliferative and immunosuppressive effects of Brucea javanica extract with CX-4945 and imatinib in human T-cell acute lymphoblastic leukemia cells

Keywords: BJ extract; Brucea javanica twig and leaves extract; T-ALL; T-cell acute lymphoblastic leukemia; CK2; Casein kinase 2; PMA; phorbol 12-myristate 13-acetate; PHA; phytohemagglutinin; 7-AAD; 7-aminoactiomycin; IL-2; Interleukin-2; Brucea javanica extract; T

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of candidate biomarkers of the exposure to PCBs in contaminated cattle: A gene expression- and proteomic-based approach

Keywords: ACN; Acetonitrile; AhR; Aryl hydrocarbon receptor; APO; Apolipoprotein; CNRQ; Calibrated normalized relative quantity; DL; Dioxin-like; ESI-Q; Electrospray ionization quadrupole; GPX; Glutathione peroxidase; HP; Haptoglobin; IL-2; Interleukin 2; LIT; Line

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Protective effects of ginsenoside Rg1 on splenocytes and thymocytes in an aging rat model induced by d-galactose

Keywords: ROS; reactive oxygen species; DNA; deoxyribonucleic acid; AGE; advanced glycation end products; MDA; malondialdehyde; SOD; superoxide dismutase; GSH; glutathione; GSSG; oxidized glutathione; SA-β-gal; senescence-associated β-galactosidase; IL-2; interle

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Enhancement of immune response of piglets to PCV-2 vaccine by porcine IL-2 and fusion IL-4/6 gene entrapped in chitosan nanoparticles

Keywords: Piglet; Co-expression; Il-2; Fusion IL-4/6; Adjuvant; Porcine circovirus-2 vaccine;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Potential of memory T cells in bridging preoperative chemoradiation and immunotherapy in rectal cancer

Keywords: Rectal cancer; Memory T cells; IL-2; Metformin; mTOR;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Bacillus subtilis CFR5 isolated from fermented soybean attenuates the chronic pancreatitis

Keywords: BSC; Bacillus subtilis CFR5; AP; acute pancreatitis; CP; chronic pancreatitis; IL-1; interleukin-1; IL-2; interleukin-2; IL-4; interleukin-4; IL-5; interleukin-5; IL-6; interleukin-6; IL-10; interleukin-10; IL-13; interleukin-13; TNF-α; tumor necrosis fa

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Anti-tumor properties of anthocyanins from Lonicera caerulea 'Beilei' fruit on human hepatocellular carcinoma: In vitro and in vivo study

Keywords: HCC; hepatocellular carcinoma; MDA; malondialdehyde; SOD; superoxide dismutase; GSH-Px; glutathione peroxidase; GSH; glutathione; IL-2; interleukin-2; IFN-γ; interferon-γ; TNF-α; tumor necrosis factor; bw/daily; body weight daily; PBS; phosphate-buffer

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Central nervous system diseases and Scutellaria: a review of current mechanism studies

Keywords: MMP-2 and MMP-9; matrix metalloproteinases; VEGF; vascular endothelial growth factor; NF-κB; nuclear factor-kappa B; HO-1; heme oxygenase-1; Nrf2; nuclear factor erythroid 2-related factor; INOS; inducible nitric oxide synthase; COX-2; cyclooxygenase-2;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of Acremonium terricola culture on performance, milk composition, rumen fermentation and immune functions in dairy cows

Keywords: ADF; acid detergent fiber; ALB; albumin; ALT; alanine transaminase; AST; aspartate transaminase; ATC; Acremonium terricola culture; BHBA; beta-hydroxybutyric acid; BUN; blood urea nitrogen; BW; body weight; CF; crude fiber; CHOL.; cholesterol; CP; crude p

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Conserved structure and function of chemokine CXCL8 between Chinese tree shrews and humans

Keywords: CXCL8; chemokine (C-X-C) ligand 8; CXCR1; C-X-C motif chemokine receptor 1; CXCR2; C-X-C motif chemokine receptor 2; Ts; tree shrew; 3D; three-dimensional; PBMCs; peripheral blood mononuclear cells; MHC; major histocompatibility complex; IL-2; interleukin

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

CCRK is a novel signalling hub exploitable in cancer immunotherapy

Keywords: 9G8; serine and arginine rich splicing factor 7; AKT; AKT serine/threonine kinase; AR; androgen receptor; ARE; androgen response element; ARG1; arginase 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and rad3-related protein; BMDC; mous

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Human T cells modulate myeloid-derived suppressor cells through a TNF-α-mediated mechanism

Keywords: Myeloid-derived suppressor cells; MDSC; PMN-MDSC; T cells; TNF-alpha; TNF-α; IL-2; Crosstalk; Reciprocal; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Interleukin-15 derived from Guanylin-GC-C-expressing macrophages inhibits fatty acid synthase in adipocytes

Keywords: dTg; double transgenic; ELISA; enzyme-linked immunosorbent assay; Fasn; fatty acid synthase; Gn; guanylin; GC-C; guanylyl cyclase C; HFD; high-fat diet; IL-2; interleukin-2; IL-2R; interleukin-2 receptor; IL-15; interleukin-15; IL-15R; interleukin-15 rece

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

Anti-pruritic and anti-inflammatory effects of oxymatrine in a mouse model of allergic contact dermatitis

Keywords: ACD; allergic contact dermatitis; CHS; contact hypersensitivity; OMT; oxymatrine; DEM; dexamethasone; SADBE; squaric acid dibutylester; IL, 13; interleukin-13; IL-2; interleukin-2; IL-6; interleukin-6; TNF-α; tumor necrosis factor α; IL-1β; interleukin

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Pretransplant serum BAFF levels are associated with pretransplant HLA immunization and renal allograft survival

Keywords: BAFF; HLA antibodies; Allosensitization; Antibody-mediated rejection; Renal allograft survival; Ab; antibody; ACR; acute T cell-mediated rejection; AMR; antibody-mediated rejection; ATG; anti-thymocyte globulin; BAFF; B cell-activating factor; BAFF-R;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Immunomodulatory, hemolytic and cytotoxic activity potentials of triterpenoid saponins from eight Cephalaria species

Keywords: Cytotoxic activity; Hemolytic activity; Immunomodulatory activity; Cephalaria; Caprifoliaceae; Triterpene saponin; HeLa; Human Cervix Adenocarcinoma; A549; Human Lung Adenocarcinoma; HEK293; Human Embryonic Kidney Cells; MTT; 3-(4,5-Dimethylthiazol-2-yl)-

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

GSNOR modulates hyperhomocysteinemia-induced T cell activation and atherosclerosis by switching Akt S-nitrosylation to phosphorylation

Keywords: ApoE; apolipoprotein E; CAD; coronary artery disease; DTT; dithiothreitol; GSNO; S-nitrosoglutathione; GSNOR; S-nitrosoglutathione reductase; Hcy; homocysteine; HHcy; hyperhomocysteinemia; IFN-γ; interferon γ; IL-2; Interleukin 2; iNOS; inducible nitric

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Diagnostic performance of GM-CSF and IL-2 in response to long-term specific-antigen cell stimulation in patients with active and latent tuberculosis infection

Keywords: Cytokine; Biomarkers; Tuberculosis; Mycobacterium tuberculosis; GM-CSF; IL-2; Immunodiagnostics;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Molecular cloning and characterization of APOBEC3 family in tree shrew

Keywords: 3DPCR; differential DNA denaturation PCR; A; adenosine; AID; activation-induced cytidine deaminase; APOBEC; apolipoprotein B mRNA-editing enzyme catalytic polypeptide proteins; APOBEC3; apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 pro

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibition of NF-κB-dependent HIV-1 replication by the marine natural product bengamide A

Keywords: HIV-1; Natural products; Bengamide A; NF-κB signaling; Long terminal repeat; CC50; 50% cytotoxic concentration; CEM-GXR; CEM-derived GXR25 GFP-reporter T cells; EC50; 50% effective concentration; GFP; green fluorescent protein; HIV; human immunodeficienc

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Astaxanthin: A mechanistic review on its biological activities and health benefits

Keywords: Astaxanthin (PubChem CID: 5368397); Beta-Carotene (PubChem CID: 5280489); Beta-Cryptoxanthin (PubChem CID: 5281235); Canthaxanthin (PubChem CID: 5281227); Lutein (PubChem CID: 5281243); Zeaxanthin (PubChem CID: 5280899); Alpha-Tocopherol (PubChem CID: 149

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Redox control of cancer cell destruction

Keywords: ABC transporters; ATP-binding cassette transporters; ADCC; antibody-dependent cell-mediated cytotoxicity; ADCP; antibody-dependent cancer cell phagocytosis; AML; acute myeloid leukemia; APE1; apurinic/apyrimidinic endonuclease 1; ASK-1; apoptosis signal-r

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Technical noteRetroviral gene transfer into primary human NK cells activated by IL-2 and K562 feeder cells expressing membrane-bound IL-21

Keywords: CFSE; carboxyfluorescein succinimidyl ester; GFP; green fluorescent protein; IL-2; interleukin 2; K562-mbIL21; K562 expressing membrane-bound IL-21; NGFR; nerve growth factor receptor; NK cells; natural killer cells; PBMC; peripheral blood mononuclear cel

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of three toxin peptides with Kv1.3 channel and IL-2 cytokine-inhibiting activities from Non-Buthidae scorpions, Chaerilus tricostatus and Chaerilus tryznai

Keywords: Chaerilidae; Kv1.3 channel; Scorpion toxin; IL-2; Potential immunoregulatory peptide;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Phase I trial of low-dose interleukin 2 therapy in patients with Wiskott-Aldrich syndrome

Keywords: WAS; Wiskott-Aldrich syndrome; XLT; X-linked thrombocytopenia; IL-2; interleukin 2; Treg; T regulatory cell; Low dose IL-2; Wiskott-Aldrich syndrome; X-linked thrombocytopenia;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Commercial gold nanocolloid inhibits synthesis of IL-2 and proliferation of porcine T lymphocytes

Keywords: AuNPs; Gold nanoparticles; FB; Facs buffer; CFSE; Carboxyfluorescein diacetate succinimidyl esther; SP; Single positive; DP; Double positive; DN; Double negative; C; Control cells; Gold nanocolloid; T cells; Proliferation; IL-2; Porcine;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Tetradecanol reduces EL-4 T cell growth by the down regulation of NF-κB mediated IL-2 secretion

Keywords: Contact dermatitis; IL-2; NF-κB; T cell; Tetradecanol;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Evaluation of profile and functionality of memory T cells in pulmonary tuberculosis

Keywords: PBMC; peripheral blood mononuclear cells; IL-17; interleukin-17; IL-2; interleukin-2; IFN- ɣ; Interferon-gamma; TNF-α; tumor necrosis factor-alpha; Mtb; Mycobacterium tuberculosis; Mtb-Ags; antigens of the strain H37Rv of Mycobacterium tuberculosis; TB;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Antitumor and immunomodulatory effects of ginsenoside Rh2 and its octyl ester derivative in H22 tumor-bearing mice

Keywords: Rh2-O; an octyl ester derivative of ginsenoside Rh2; IL-2; interleukin-2; TNF-α; tumor necrosis factor; VEGF; vascular endothelial growth factor; HCC; hepatocellular carcinoma; CTX; cyclophosphamide; FBS; Fetal bovine serum; ELISA; enzyme-linked immunoso

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Staphylococcal enterotoxin C2 mutant drives T lymphocyte activation through PI3K/mTOR and NF-ĸB signaling pathways

Keywords: Staphylococcal enterotoxin C2; PI3K; mTOR; NF-ĸB; Proliferation; IL-2;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Human amniotic epithelial cells inhibit CD4+ T cell activation in acute kidney injury patients by influencing the miR-101-c-Rel-IL-2 pathway

Keywords: Human amniotic epithelial cells (HuAECs); Acute kidney injury (AKI); CD4+ T; MicroRNA-101 (miR-101); c-Rel; IL-2;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleThe Quantitative and Functional Changes of Postoperative Peripheral Blood Immune Cell Subsets Relate to Prognosis of Patients with Subarachnoid Hemorrhage: A Preliminary Study

Keywords: Clipping surgery; Immune function; Inflammatory cytokines; Lymphocyte subsets; Peripheral blood leukocytes; SAH; GOS; Glasgow Outcome Scale; IFN-γ; Interferon γ; IL-2; Interleukin 2; IVGTT; Intravenous glucose tolerance test; NK; Natural killer; NKG2D;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Cibles et immunothérapies innovantes dans le traitement de l'allergie alimentaire

Keywords: Allergie alimentaire; Immunothérapie; Cibles; Innovation; Treg; IL-2; Food allergy; Immunotherapy; Targets; Innovation; Treg; IL-2;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

NFKB1 regulates human NK cell maturation and effector functions

Keywords: NFKB1; Nuclear Factor kappa-B, subunit 1; CVID; Common Variable Immunodeficiency; NFKB2; Nuclear Factor kappa-B, subunit 2; NK cells; natural killer cells; IFN-γ; Interferon-gamma; MFI; mean fluorescence intensity; IL-2; Interleukin-2; IL-12; Interleukin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Enhanced antitumor activity of gemcitabine by polysaccharide-induced NK cell activation and immune cytotoxicity reduction in vitro/vivo

Keywords: SEP; A polysaccharide isolated from Strongylocentrotus nudus egg; TLR; toll-like receptor; NKG2D; natural-killer group 2 member D; DAP10; DNAX-associated protein 10; Akt; protein kinase B; MICA; MHC class I-related chain A; sMICA; soluble MHC class I-rela

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Discovery of tricyclic dipyrrolopyridine derivatives as novel JAK inhibitors

Keywords: Janus kinase inhibitor; IL-2; Organ transplant rejection; Autoimmune diseases; Immunomodulator;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Cysteinyl leukotriene E4 activates human group 2 innate lymphoid cells and enhances the effect of prostaglandin D2 and epithelial cytokines

Keywords: Group 2 innate lymphoid cell; leukotriene E4; prostaglandin D2; IL-25; IL-33; IL-2; thymic stromal lymphopoietin; atopic dermatitis; CRTH2; Chemoattractant receptor-homologous molecule expressed on TH2 cells; CSF1; Macrophage colony-stimulating factor; cy

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2017 سفارش ترجمه

Protective effect of bacillopeptidase CFR5 from Bacillus subtilis CFR5 on cerulein-induced pancreatitis

Keywords: Pancreatitis; Interleukin; Bacillopeptidase; Cytokines; Tight junction protein; BPC; bacillopeptidase CFR5; CIP; cerulein induced acute pancreatitis; IL-1; interleukin-1; IL-6; interleukin-6; IL-2; interleukin-2; IL-4; interleukin-4; IL-5; interleukin-5;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه