Galectin-1 reduced the effect of LPS on the IL-6 production in decidual cells by inhibiting LPS on the stimulation of IκBζ
Keywords: Galectin-1; Pregnancy; NF-κB; IL-6; IκBζ;
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Adiponectin, leptin, interleukin-6 and HbA1c in the prediction of incident type 2 diabetes: A nested case-control study in Asian Indian men with impaired glucose tolerance
Keywords: AUC; area under curve; BMI; body mass index; CI; confidence interval; CVD; cardiovasular disease; CVS; coefficients of variations; ELISA; enzyme-linked immunosorbent assay; EPIC; European prospective investigation into cancer and nutrition; HDL-chol; high
SOHO Supplement 2015Imbalance of Pro- and Anti-Inflammatory Cytokines in Patients With cHL Persists Despite Treatment Compared With Control Subjects
Keywords: Hodgkin lymphoma; IL-10; IL-6; sCD25; Treatment;
Original StudyDevelopment of Predictive Value of Urinary Cytokine Profile Induced During Intravesical Bacillus Calmette-Guérin Instillations for Bladder Cancer
Keywords: BCG; IL-2; IL-6; NMIBC; Recurrence; Response;
Mycobacterium tuberculosis Rv2185c contributes to nuclear factor-κB activation
Keywords: TB; tuberculosis; NF-κB; nuclear factor-κB; IL-6; interleukin-6; TNF-α; tumor necrosis factor-α; TRAIL; apoptosis-inducing ligand; Mycobacterium tuberculosis; Rv2185c; Nuclear factor-κB (NF-κB); Cytokines; Apoptosis;
Clinical and serum-based markers are associated with death within 1 year of de novo implant in primary prevention ICD recipients
Keywords: AUC; area under the curve; BNP; brain natriuretic peptide; CI; confidence interval; CK-MB; creatine kinase MB; CRP; C-reactive protein; cTnI; cardiac troponin I; cTnT; cardiac troponin T; CV; coefficient of variation; eGFR; estimated glomerular filtration
Relationships between IL-6 gene polymorphism, low BMD and periodontitis in postmenopausal women
Keywords: IL-6; Polymorphism; Low BMD; Periodontitis;
Acute nitrogen dioxide (NO2) exposure enhances airway inflammation via modulating Th1/Th2 differentiation and activating JAK-STAT pathway
Keywords: NO2; nitrogen dioxide; MUC5AC; mucin gene; IL-1β; Interleukin-1β; IL-6; Interleukin-6; ICAM-1; intercellular adhesion molecule; Th2; subtype of helper T lymphocyte; JAK; Janus kinase; STAT; signal transducer and activator of transcription; IL-4; Interle
TLR2-MyD88-NF-κB pathway is involved in tubulointerstitial inflammation caused by proteinuria
Keywords: Proteinuria; Tubulointerstitial inflammation; TLR2-MyD88-NF-κB pathway; TNF-α; IL-6;
Relationship of obesity with serum concentrations of leptin, CRP and IL-6 in breast cancer survivors
Keywords: Obesity; Breast cancer; Leptin; C-reactive protein; IL-6
New strategy for diagnosing embryo implantation potential by combining proteomics and time-lapse technologies
Keywords: Embryo kinetics; blastocyst; time lapse; implantation potential; proteomics; IL-6
MgcRacGAP inhibition stimulates JAK-dependent STAT3 activity
Keywords: GAP; GTPase Activating Protein; GTPase; guanosine triphosphatase; HEK293 SIE-Luc; HEK293 GloResponse SIE Luc2P Hygro cells; IL-6; interleukin-6; MgcRacGAP; male germ cell Rac GTPase-activating protein; MINC1; MgcRacGAP inhibitor compound 1; STAT3; signal
Acidic environment augments FcεRI-mediated production of IL-6 and IL-13 in mast cells
Keywords: Extracellular acidification; IL-6; IL-13; Interleukin; Mast cells; p38 MAPK;
SENP1 inhibition induces apoptosis and growth arrest of multiple myeloma cells through modulation of NF-κB signaling
Keywords: Senp1; Multiple myeloma; IL-6; NF-кB;
Blood-cell bioenergetics are associated with physical function and inflammation in overweight/obese older adults
Keywords: ATP; adenosine triphosphate; BMI; body mass index; DXA; dual energy X-ray absorptiometry; ELISA; enzyme-linked immunosorbent assay; ETC; electron transport chain; Ex-SPPB; expanded short physical performance battery; FCCP; carbonyl cyanide-4-(trifluoromet
Oxidative stress and inflammation in mucopolysaccharidosis type IVA patients treated with enzyme replacement therapy
Keywords: 8-OHdG; 8-hydroxy-2â²-deoxyguanosine; CAT; catalase; Cr; creatinine; DI; damage index; Di-Tyr; di-tyrosine; DMB; 1,9-dimethylmethylene blue; DTNB; 5,5â²-dithiobis(2-nitrobenzoic acid); Endo III; endonuclease III; ELISA; enzyme-linked immunoassay; ERT; e
A single dose of inactivated hepatitis A vaccine promotes HAV-specific memory cellular response similar to that induced by a natural infection
Keywords: Hepatitis A vaccine; Single dose; Central memory cells; Effector memory cells; Cellular response; HAV; hepatitis A virus; WHO; World Health Organization; SAGE; Strategic Advisory Group of Experts; Anti-HAV; hepatitis A virus antibodies; BMI; body mass ind
Research ArticleDysregulated miR-124 and miR-200 expression contribute to cholangiocyte proliferation in the cholestatic liver by targeting IL-6/STAT3 signalling
Keywords: miRNA; microRNA; 3â² UTR; 3â² untranslated region; mRNA; messenger RNA; IL-6; interleukin-6; STAT3; signal transducer and activator of transcription 3; PCR; polymerase chain reaction; PCNA; proliferating cell nuclear antigen; GAPDH; glyceraldehyde 3-pho
Mesenchymal stem cells promote CD206 expression and phagocytic activity of macrophages through IL-6 in systemic lupus erythematosus
Keywords: Umbilical cord-derived mesenchymal stem cells; Systemic lupus erythematosus; Macrophage; IL-6;
Central mediators involved in the febrile response induced by polyinosinic-polycytidylic acid: Lack of involvement of endothelins and substance P
Keywords: ANOVA; analysis of variance; dsRNA; double-stranded RNA; HLI; heat loss index; i.c.v; intracerebroventricular; IFN; interferon; IRF; interferon-regulatory factor; IL-1RA; interleukin-1 receptor antagonist; IL-1β; interleukin-1β; IL-6; interleukin-6; IL-
IGF-1 attenuates LPS induced pro-inflammatory cytokines expression in buffalo (Bubalus bubalis) granulosa cells
Keywords: NEB; negative energy balance; LPS; lipopolysaccharides; IGF-1; insulin-like growth factor-1; IL-1β; interleukin-1beta; TNF-α; tumor necrosis factor-alpha; IL-6; interleukin-6; CYP19A1; cytochrome P450 aromatase A1; ERK1/2; extracellular signal-regulated
MicroRNA-146a reduces IL-1 dependent inflammatory responses in the intervertebral disc
Keywords: ADAMTS; a disintergrin and metalloproteinase with thrombospondin motifs; ANOVA; analysis of variance; COX-2; cyclooxygenase-2; Ct; threshold cycle; DAB; 3, 3â²-diaminobenzidine; DMEM; Dulbecco's modified eagle medium; IHC; immunohistochemical; EGFR; epid
MicroRNA-494 inhibits the growth and angiogenesis-regulating potential of mesenchymal stem cells
Keywords: microRNAs; miRNAs or miRs; miR-494; microRNA-494-3p; MSCs; mesenchymal stem cells; dMSCs; decidua-derived MSCs; PE; preeclampsia; mi-494; miR-494 mimic; mi-NC; miR-494 mimic negative control; si-RNA; small interfering RNA; VEGF; vascular endothelial growt
Blockage of Wnt/β-catenin signaling by quercetin reduces survival and proliferation of B-1 cells in vitro
Keywords: APC; adenomatous polyposis coli; CLL; chronic lymphocytic leukemia; Fz; frizzled receptor; GSK-3β; glycogen synthase kinase; HSC; hematopoietic stem cells; LDL; low-density lipoprotein; Lef; lymphoid enhancing factor; LRP; LDL receptor-related protein; P
Androgen receptors and experimental bone loss - an in vivo and in vitro study
Keywords: GnRH; Gonadotropin-releasing hormone; sIL6r; Soluble interleukin-6 receptor; IL-6; Interleukin-6; IL-1β; Interleukin-1β; TNF; Tumor necrosis factor; MIP; Macrophage inflammatory protein; DHT; Dihydrotestosterone; GPR30; G-protein coupled receptor-30; Bo
Docosahexaenoic acid differentially affects TNFα and IL-6 expression in LPS-stimulated RAW 264.7 murine macrophages
Keywords: TNFα; IL-6; TLR4; Macrophages; PGE2; CREB
The role of serum IL-17 and IL-6 as biomarkers of disease activity and predictors of remission in patients with lupus nephritis
Keywords: SLE; IL-17; IL-6; Disease activity; Lupus nephritis
IL-6, IL-10, c-Jun and STAT3 expression in B-CLL
Keywords: B-CLL; IL-6; IL-10; c-Jun; STAT3
Scutellarin protects against the liver injury induced by diosbulbin B in mice and its mechanism
Keywords: DB; diosbulbin B; SC; scutellarin; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ALP; alkaline phosphatase; MPO; myeloperoxidase; TNF-α; tumor necrosis factor alpha; IL-6; interleukin 6; IFN-γ; interferon-γ; IκB; inhibitor of kappa B
Lariciresinol-4-O-β-D-glucopyranoside from the root of Isatis indigotica inhibits influenza A virus-induced pro-inflammatory response
Keywords: IL-6; interleukin-6; IL-8; interleukin-8; MCP-1; monocytes chemotactic factor; IP-10; interferon gamma-induced protein 10; IFN-α; interferon alpha; NF-κB; Nuclear factor-κB; TNF-α; tumor necrosis factor alpha; RNP; ribonucleoprotein; MTT; methylthiazo
Hyperin attenuates inflammation by activating PPAR-γ in mice with acute liver injury (ALI) and LPS-induced RAW264.7 cells
Keywords: HP; hyperin; ALI; acute liver injury; LPS; lipopolysaccharide; PPAR-γ; peroxisome proliferator-activated receptor gamma; ERK; extracellular signal-regulated kinase; TNF-α; tumor necrotic factor alpha; IL-6; interleukin-6; AST; aspartate transaminase; AL
The protective effect of 18β-Glycyrrhetinic acid against UV irradiation induced photoaging in mice
Keywords: UV; ultraviolet; GA; 18β-Glycyrrhetinic acid; MMPs; matrix metalloproteinases; ROS; reactive oxygen species; MAPK; mitogen-activated protein kinase; NC; naive control group; SC; shaved control group; MC; model control group; VC; vehicle control group; GA
SIGNR1-mediated phagocytosis, but not SIGNR1-mediated endocytosis or cell adhesion, suppresses LPS-induced secretion of IL-6 from murine macrophages
Keywords: SIGNR1; Phagocytosis; Endocytosis; Cell adhesion; IL-6;
Tyrosine kinase inhibitor tyrphostin AG490 reduces liver injury in LPS-induced shock
Keywords: Tyrphostin AG490 (PubChem CID: 5328771)RANTES; IL-6; IL-12; iNOS; STAT3; pSTAT3
Bacterial flagellin induces IL-6 expression in human basophils
Keywords: Basophils; KU812; Flagellin; TLR5; IL-6
Calpain inhibitor, MDL 28170 confer electrophysiological, nociceptive and biochemical improvement in diabetic neuropathy
Keywords: Calpain; Diabetic neuropathy; Dorsal root ganglion; MDL 28170; Tetrodotoxin-resistant sodium channels; DN; Diabetic neuropathy; DRG; Dorsal root ganglion; IL-6; Interlukin-6; INa; Sodium current; MDA; Malondialdehyde; MNCV; Motor nerve conduction velocity
Ethyl acetate fraction of Cissus quadrangularis stem ameliorates hyperglycaemia-mediated oxidative stress and suppresses inflammatory response in nicotinamide/streptozotocin induced type 2 diabetic rats
Keywords: Diabetes mellitus; Antioxidants; Quercetin; Oxidative stress; Inflammation; DM; Diabetes mellitus; T2DM; Type 2 diabetes mellitus; ROS; Reactive oxygen species; NF-κB; Nuclear factor kappa B; TNF-α; Tumor necrosis factor-alpha; IL-6; Interleukin-6; CQ;
Lysophosphatidylcholine exacerbates Leishmania major-dendritic cell infection through interleukin-10 and a burst in arginase1 and indoleamine 2,3-dioxygenase activities
Keywords: BMDC; Bone marrow-derived dendritic cells; IDO; Indoleamine 2,3-dioxygenase; iNOS; inducible nitric oxide synthase; IL-6; Interleukin-6; IL-10; Interleukin-10; kyn; kynurenine; Leish; Leishmania; LIPA; Leishmania Institut Pasteur Alger; LPS; Lipopolysacch
Fibroblast growth factor 21 (FGF21) ameliorates collagen-induced arthritis through modulating oxidative stress and suppressing nuclear factor-kappa B pathway
Keywords: RA; rheumatoid arthritis; FGF21; fibroblast growth factor 21; CIA; collagen-induced arthritis; IL-1β; interleukin-1β; TNF-α; tumor necrosis factor; IL-6; interleukin-6; IFN-γ; interferon-γ; MMP-3; matrix metalloproteinase-3; IL-10; interleukin-10; DE
Interleukin 6 inhibits HBV entry through NTCP down regulation
Keywords: HBV; Hepatitis B virus; NTCP; Sodium taurocholate co-transporting polypeptide; IL-6; Interleukin 6; IFN γ; Interferon gamma; ALT; Alanine aminotransferase; TNFα; Tumor Necrosis Factor alpha; IL-1β; Interleukin 1 beta; OSM; Oncostatin M; PHH; Primary Hu
Research ArticleRole for the endoplasmic reticulum stress sensor IRE1α in liver regenerative responses
Keywords: IRE1α; inositol-requiring enzyme 1α; ER; endoplasmic reticulum; CCl4; carbon tetrachloride; PH; partial hepatectomy; UPR; unfolded protein response; LKO; liver specific IRE1α knockout; IL-6; interleukin 6; STAT3; signal transducer and activator of tran
The effect of 4α,5α-epoxy-10α,14-dihydro-inuviscolide, a novel immunosuppressant isolated from Carpesium abrotanoides, on the cytokine profile in vitro and in vivo
Keywords: TNFα; tumor necrosis factor alpha; IL-6; interleukin 6; IL-4; interleukin 4; IL-13; interleukin 13; IFNγ; interferon gamma; IL-10; interleukin 10; NF-κB; nuclear factor-kappa B lymphocyte; IKK; IκB kinase complex; MAPK; mitogen-activated protein kinas
Research ArticleExpression and functionality of Toll- and RIG-like receptors in HepaRG cells
Keywords: PHH; primary human hepatocyte; TLR; toll-like receptor; RIG-I; retinoic acid-inducible gene 1; RLR; RIG-like receptor; RT; reverse transcription; qPCR; quantitative polymerase chain reaction; FACS; fluorescence-activated cell sorting; IL-6; interleukin-6;
IL-6 blockade reverses the abnormal STAT activation of peripheral blood leukocytes from rheumatoid arthritis patients
Keywords: Rheumatoid arthritis; IL-6; STATs; Leukocytes; Tocilizumab;
The anti-inflammatory activities of Ainsliaea fragrans Champ. extract and its components in lipopolysaccharide-stimulated RAW264.7 macrophages through inhibition of NF-κB pathway
Keywords: LPS; lipopolysaccharide; NO; nitric oxide; iNOS; inducible nitric oxide synthase; TNF-α; tumor necrosis factor-alpha; IL-6; interleukin-6; IκBα; inhibitory κBα; NF-κB; nuclear factor-κB; Ainsliaea fragrans Champ.; Dicaffeoylquinic acid; Gynecologic
The intracerebroventricular injection of rimonabant inhibits systemic lipopolysaccharide-induced lung inflammation
Keywords: ICV; intracerebroventricular; CB1; cannabinoid receptor type 1; LPS; lipopolysaccharide; IV; intravenous; Ppc; pulmonary capillary pressure; TLR4; toll-like receptor 4; IRAK1; interleukin receptor-associated kinase-1; IκBα; inhibitor of nuclear factor o
The effect of HMGB1 on sub-toxic chlorpyrifos exposure-induced neuroinflammation in amygdala of neonatal rats
Keywords: CPF; chlorpyrifos; SN; substantia nigra; HMGB1; high-mobility group box 1; NF-κB; nuclear factor kappa B; DMSO; dimethyl sulfoxide; IL-6; interleukin-6; TNF-α; tumor necrosis factor-α; Chlorpyrifos; Inflammatory; High-mobility group box 1; Nuclear fact
Effect of chronic p,pâ²-dichlorodiphenyldichloroethylene (DDE) exposure on high fat diet-induced alterations in glucose and lipid metabolism in male C57BL/6H mice
Keywords: DDE; p,pâ²-dichlorodiphenyldichloroethylene; DDT; p,pâ²-dichlorodiphenyltrichloroethane; T2D; type 2 diabetes mellitus; POP; spersistent organic pollutants; OC; organochlorine compound; NHANES; National Health and Nutrition Examination Survey; AAALAC; A
In vitro evaluation of the cytotoxicity and modulation of mechanisms associated with inflammation induced by perfluorooctanesulfonate and perfluorooctanoic acid in human colon myofibroblasts CCD-18Co
Keywords: BSA; bovine serum albumin; DMSO; dimethyl sulfoxide; FBS; fetal bovine serum; IL-1β; interleukin-1β; IL-6; interleukin-6; LPS; lipopolysaccharide; NOAEL; lowest no-observed-adverse-effect level; PFASs; perfluorinated compounds; PFOS; perfluoroalkyl and
Original articleChanges of hepatic lipid mediators associated with intake of high-fat diet for 12 weeks in endotoxemic rats using LC-ESI-MS/MS
Keywords: Lipid mediator; Lipidomics; High-fat diet; Lard; Sepsis; Lipopolysaccharide; CD; control diet; HFD; high-fat diet; LPS; lipopolysaccharide; TNF-α; tumor necrosis factor-α; IL-6; interleukin-6; iNOS; inducible nitric oxide synthase; AA; arachidonic acid;