Keywords: ABCB1; SLC28A2; IL28B; AKR1; BCRP1; FokI;
مقالات ISI (ترجمه نشده)
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Keywords: Hepatitis B; Guidelines; Antiviral Therapy; Peginterferon alfa-2a; Entecavir; Tenofovir; Resistance; AFP; alpha-fetoprotein; ALT; alanine aminotransferase; anti-HBc; antibody to hepatitis B core antigen; anti-HBe; antibody to hepatitis B e antigen; anti-H
Genetic variation on the NFKB1 genes associates with the outcomes of HCV infection among Chinese Han population
Keywords: Hepatitis C virus; Nuclear factor-kappa B; Transcription; Polymorphism; NFKB1; nuclear factor-kappa B1; HCV; hepatitis C virus; HCC; hepatocellular carcinoma; LRD; liver-related death; NF-κB; nuclear factor-kappa B; SNPs; single nucleotide polymorphisms;
Role of IL28B genotype in the liver stiffness increase in untreated patients with chronic hepatitis C
Keywords: CHC; chronic hepatitis C; HCV; Hepatitis C virus; PEG-IFN; pegylated interferon alfa; RBV; ribavirin; DAAs; direct-acting antiviral agents; GT1; genotype 1; GT4; genotype 4; IQR; inter-quartile range; OR; odds ratio; HCV; IL28B; Liver stiffness; Fibrosis
IL28B gene variants and glucose metabolism in Type 2 Diabetes
Keywords: T2D; Type 2 Diabetes; HC; healthy controls; IL28B; interleukin-28B; HCV; hepatitis C virus; HOMA-IR; homeostasis model assessment of insulin resistance; BMI; body mass index; HbA1c; hemoglobin A1c; T2D; IL28B; HOMA-IR; Glucose;
Pretreatment serum levels of interferon-gamma-inducible protein-10 are associated with virologic response to telaprevir-based therapy
Keywords: Chronic hepatitis C; IL28B; IP-10; Rapid virologic response; Telaprevir; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CHC; chronic hepatitis C; CI; confidential interval; DAA; direct-acting antivirals; ETR; end of treatment virologic re
IFNL4 ss469415590 polymorphism contributes to treatment decisions in patients with chronic hepatitis C virus genotype 1b, but not 2a, infection
Keywords: ALT; alanine aminotransferase; AST; aspartate aminotransferase; BMI; body mass index; cEVR; complete early virological response; CHC; chronic hepatitis C; CI; confidence interval; ETVR; end-of-treatment virological response; EVR; early virological respons
Research ArticleEfficacy and safety of ombitasvir/paritaprevir/r and dasabuvir compared to IFN-containing regimens in genotype 1 HCV patients: The MALACHITE-I/II trials
Keywords: HCV; hepatitis C virus; GT; genotype; TPV; telaprevir; PegIFN; pegylated interferon; RBV; ribavirin; SVR; sustained virologic response; DAA; direct-acting antiviral agents; OBV; ombitasvir; PTV; paritaprevir; r; ritonavir; DSV; dasabuvir; IL28B; interleuk
The complete title: The effect of interleukin-28B rs12979860 polymorphism on the therapeutic response of Moroccan patients with chronic hepatitis C
Keywords: SNP; single nucleotide polymorphisms; IL28B; interleukin-28B; HRM; high resolution melting technical; IFN/RBV; pegylated-interferon/ribavirin; HCV; hepatitis C virus; SVR; sustained virologic response; HBsAg; HBV surface antigen; HIV; Human Immunodeficien
Roles of ITPA and IL28B genotypes in chronic Hepatitis C patients treated with peginterferon plus ribavirin in Tunisian population
Keywords: ITPA; inosine triphosphate; SVR; sustained virological response; HCV; hepatitis C virus; HCC; hepatocellular carcinoma; PEG-IFN; pegylated interferon; GWAS; Genome Wide Association Study; SNPs; single nucleotide polymorphisms; III IFN; interferon III; IL2
Interferon-λ4 is a cell-autonomous type III interferon associated with pre-treatment hepatitis C virus burden
Keywords: Hepatitis C virus; IL28B; Genome-wide association study; Flaviviridae; Sustained virological response;
Polymorphism of the IL28B gene (rs8099917, rs12979860) and virological response of Pakistani hepatitis C virus genotype 3 patients to pegylated interferon therapy
Keywords: IL28B; HCV genotype 3; PEG-IFN
Research ArticleComparison of functional variants in IFNL4 and IFNL3 for association with HCV clearance
Keywords: Genetics; IL28B; IFNL3; IFNL4; Innate immunity; Interferon lambda; Treatment; Viral clearance;
Role of IL-28B polymorphisms in virologic response to combined pegylated interferon and ribavirin therapy in genotype 4 chronic HCV infected patients with and without cirrhosis
Keywords: HCV; IL28B; Polymorphism; Interferon; Schistosomiasis; Response
IFNL4 ss469415590 polymorphism is associated with unfavourable clinical and immunological status in HIV-infected individuals
Keywords: HIV infection; AIDS; CD4; IFNL4; IL28B;
Comparison of four methods of genotyping IL28B polymorphisms in chronic hepatitis C patients
Keywords: IL28B; SNP; HCV; Brazil; ARMS-PCR;
Liver, Pancreas and Biliary TractNo impact of interleukin-28B polymorphisms on spontaneous or drug-induced hepatitis delta virus clearance
Keywords: HDV infection; IFN treatment; IL28B; Viral clearance;
Case ReportOccasional spontaneous clearance of chronic hepatitis C virus in HIV-infected individuals
Keywords: HCV; hepatitis C virus; HIV; human immunodeficiency virus; IL28B; interleukin 28B; peg-IFN; pegylated interferon; HBV; hepatitis B virus; SNP; single nucleotide polymorphism; ART; antiretroviral treatment; ALT; alanine transaminase; AST; aspartate transam
Low IL10 serum levels as key factor for predicting the sustained virological response to IFNα/ribavirin in Brazilian patients with HCV carrying IL28B CT/TT genotype
Keywords: IL28b; IL10; HCV; Therapy; Polymorphism
Evaluation of the relationship between IL28B, IL10RB and IL28RA single-nucleotide polymorphisms and susceptibility to hepatitis C virus in Chinese Han population
Keywords: IL28B; IL10RB; IL28RA; Hepatitis C virus (HCV); High resolution melt (HRM); Polymorphism;
Influence of low-density lipoprotein cholesterol on virological response to telaprevir-based triple therapy for chronic HCV genotype 1b infection
Keywords: Hepatitis C; Telaprevir; Low-density lipoprotein cholesterol; IL28B; Pegylated interferon
Peripheral blood mononuclear cells microRNA predicts treatment outcome of hepatitis C virus genotype 1 infection
Keywords: HCV; PBMC; MicroRNA; SVR; IL28B; miR-125b;
The influence of single and combined IL28B polymorphisms on response to treatment of chronic hepatitis C
Keywords: IL28B; Hepatitis C virus (HCV); Single nucleotide polymorphism (SNP); Sustained virological response (SVR);
Association study of IL28B: rs12979860 and rs8099917 polymorphisms with SVR in patients infected with chronic HCV genotype 1 to PEG-INF/RBV therapy using systematic meta-analysis
Keywords: GWAS; genome-wide associated studies; HCV; hepatitis C virus; PEG-INF/RBV; pegylated interferon/ribavirin; IP-10; IFN-gamma inducible protein-10; IL28B; Interluekin-28B; CHC; chronic hepatitis C; CNKI; Chinese National Knowledge Infrastructure; SVR; Susta
Research ArticleA phase 2a trial of 12-week interferon-free therapy with two direct-acting antivirals (ABT-450/r, ABT-072) and ribavirin in IL28B C/C patients with chronic hepatitis C genotype 1
Keywords: HCV; hepatitis C virus; CYP3A4; cytochrome P450 isoform 3A4; RNA; ribonucleic acid; IL28B; interleukin-28B; LiPA; Versant® HCV Genotype Inno-LiPA Assay, version 2.0; MedDRA; Medical Dictionary for Regulatory Activities; OATP1B1; organic anion transportin
Importance of IL-10 and IL-6 during chronic hepatitis c genotype-1 treatment and their relation with IL28B
Keywords: IL-10; interleukin 10; IL-6; interleukin 6; HCV; hepatitis C virus; CHC; chronic hepatitis C; CHC-GT1; chronic hepatitis C genotype 1; SVR; sustained virological response; SNP; single-nucleotide polymorphism; IL28B; interleukin 28B; IFN; interferon; pegIF
Research ArticleTelaprevir can be successfully and safely used to treat older patients with genotype 1b chronic hepatitis C
Keywords: TVR; telaprevir; RVR; rapid virological response; SVR; sustained virological response; IL28B; interleukin 28B; HCV; hepatitis C virus; HCC; hepatocellular carcinoma; PegIFN-α; pegylated interferon α; RBV; ribavirin; NS3/4A; non-structural 3/4A; DAA; dir
ReviewPerspectives and challenges of interferon-free therapy for chronic hepatitis C
Keywords: HCV; hepatitis C virus; HIV; human immunodeficiency virus; SVR; sustained virologic response; RVR; rapid virologic response; eRVR; extended rapid virologic response; EVR; early virologic response; peg; pegylated; IFN; interferon; IL28B; interleukin 28B; D
Pegylated interferon plus ribavirin is suboptimal in IL28B CC carriers without rapid response
Keywords: Hepatitis C; HIV; Pegylated interferon; Ribavirin; Boceprevir; Telaprevir; IL28B; Rapid virological response
Different effects of three interferons L on Toll-like receptor-related gene expression in HepG2 cells
Keywords: Hepatitis C virus; IL28B; Innate immune response; ISGs; Toll-like receptor
Directly acting antivirals for the treatment of chronic hepatitis C: Unresolved topics from registration trials
Keywords: Boceprevir; Cirrhosis; Guidelines; HCV; IL28B; Lead-in; Telaprevir
Different impact of IL28B polymorphisms on response to peginterferon-α plus ribavirin in HIV-positive patients infected with HCV subtypes 1a or 1b
Keywords: Hepatitis C; IL28B; HCV-1 subtypes; Coinfection;
Short communicationEvaluation of interleukin 28B single nucleotide polymorphisms in infants suffering from bronchiolitis
Keywords: RSV; IFN; IL28B; Bronchiolitis; Viral load; Respiratory virus;
A straightforward genotyping of the relevant IL28B SNPs for the prediction of hepatitis C treatment outcome
Keywords: IL28B; Single Nucleotide Polymorphism; PCR-RFLP; Hepatitis C
Research ArticleIL28B polymorphism is associated with treatment response in patients with genotype 4 chronic hepatitis C
Keywords: GWAS; genome wide association study; HCV; hepatitis C virus; IFN-λ3; interferon λ3; IL28B; interleukin 28B; NR; non response; PCR; polymerase chain reaction; PEG-IFN; pegylated interferon; RVR; rapid virological response; SNP; single nucleotide polymorp
Research ArticleAssociation of the IL28B genotype with insulin resistance in patients with chronic hepatitis C
Keywords: CHC; chronic hepatitis C; HCV; hepatitis C virus; HOMA; homeostasis model of assessment; IR; insulin resistance; IL28B; interleukin 28 B; PNPLA3; patatin like phospholipase domain-containing 3; SVR; sustained virologic response; SNP; single nucleotide pol
Research ArticleRaloxifene hydrochloride is an adjuvant antiviral treatment of postmenopausal women with chronic hepatitis C: A randomized trial
Keywords: HCV; hepatitis C virus; SVR; sustained virological response; SOC; standard of care; PegIFN; pegylated interferon; RBV; ribavirin; RLX; raloxifene hydrochloride; IL28B; interleukin-28B; SERM; selective estrogen receptor modulator; WBC; white blood cell; Hb
Research ArticlePrediction of response to pegylated interferon plus ribavirin in HIV/hepatitis C virus (HCV)-coinfected patients using HCV genotype, IL28B variations, and HCV-RNA load
Keywords: HCV; hepatitis C virus; Peg-IFN; pegylated interferon; RBV; ribavirin; SNP; single nucleotide polymorphism; IL28B; interleukin 28B; SVR; sustained virologic response; DAA; directly acting agents; Hepatitis C; Interleukin 28B; Interferon; Ribavirin; Genoty
Research ArticleIL28B and PNPLA3 polymorphisms affect histological liver damage in patients with non-alcoholic fatty liver disease
Keywords: IL28B; interleukin 28B; PNPLA3; patatin-like phospholipase-3; UA; uric acid; IR; insulin resistance; NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; HOMA; homeostasis model assessment; IL28B; NASH;
Research ArticleGenome-wide association study of interferon-related cytopenia in chronic hepatitis C patients
Keywords: HCV; hepatitis C virus; pegIFN; pegylated-interferon-alfa; RBV; ribavirin; DARC; Duffy Antigen Receptor for Chemokines; IL28B; Iinterleukin 28B; ITPA; inosine triphosphatase gene; ITPase; inosine triphosphatase; ANC; absolute neutrophil count; Pl; platele
Research ArticleInsulin resistance undermines the advantages of IL28B polymorphism in the pegylated interferon alpha-2b and ribavirin treatment of chronic hepatitis C patients with genotype 1
Keywords: HCV; hepatitis C virus; HCC; hepatocellular carcinoma; PegIFN; pegylated interferon; RBV; ribavirin; SVR; sustained virological response; SNPs; single nucleotide polymorphisms; IL28B; interleukin 28B; BMI; body mass index; HOMA-IR; Homeostasis Model Asses
IL28B Polymorphisms as a Pretreatment Predictor of Response to HCV Treatment
Keywords: IL28B; Pharmacogenomics; Antiviral; Type III interferon; Interferon-lambda;
The role of viral and host genetics in natural history and treatment of chronic HCV infection
Keywords: Hepatitis C virus; Genetics; Genome-wide association; Natural history; Treatment; IL28B; Single nucleotide polymorphism
Liver transplantation in the setting of chronic HCV
Keywords: Recurrent cirrhosis; Cholestatic hepatitis; Donor age; IL28B; Liver biopsy; Elastography; Peginterferon; Ribavirin; Protease inhibitors
Interleukin 28B genotype determination using DNA from different sources: A simple and reliable tool for the epidemiological and clinical characterization of hepatitis C
Keywords: IL; interleukin; HCV; hepatitis C virus; PCR; polymerase chain reaction; PEG-IFN; pegylated interferon; RBV; ribavirin; SNP; single nucleotide polymorphism; RT; room temperature; Hepatitis C virus (HCV); IL28B; Pharmacogenetics; Interferon; Formalin-fixed
Real-time polymerase chain reaction assay based on high-resolution melting analysis for the determination of the rs12979860 polymorphism involved in hepatitis C treatment response
Keywords: Real-time PCR; High-resolution melting (HRM) analysis; Hepatitis C; Rs12979860 polymorphism; IL28B;
International HepatologyA sprint to increase response to HCV treatment: Expectancies but caution
Keywords: DAA; direct acting antivirals; SVR; sustained virological response; RVR; rapid virological response; PEG-IFN; pegylated-interferon; RBV; ribavirin; Boceprevir; Pegylated interferon; Ribavirin; Protease inhibitors; IL28B;
Research ArticleImpact of donor and recipient IL28B rs12979860 genotypes on hepatitis C virus liver graft reinfection
Keywords: ALT; alanine aminotransferase; HCV; hepatitis C virus; IFN; interferon; IL28B; interleukin 28B; PEG-IFN-α; pegylated interferon-α; RVR; rapid virologic response; SNP; single nucleotide polymorphism; SVR; sustained virologic response; HCV; Interferon-α;
Research ArticleThe predictive value of IL28B gene polymorphism for spontaneous clearance in a single source outbreak cohort is limited in patients carrying the CCR5Î32 mutation
Keywords: HCV; hepatitis C virus; IL28B; interleukin 28B; IFN; interferon; SNP; single nucleotide polymorphism; CCR5; CC chemokin receptor 5; pDC; plasmacytoid dendritic cells; WT; wildtype; HIV; human immunodeficiency virus; Hepatitis C virus; IL28B; CCR5; Polymor
Research ArticleImportance of IL28B gene polymorphisms in hepatitis C virus genotype 2 and 3 infected patients
Keywords: IL28B; Gene polymorphism; Hepatitis C virus; Genotype 2; Genotype 3; IL28B; interleukin 28B gene; HCV; hepatitis C virus; SNP; single nucleotide polymorphism; WHO; World Health Organisation; SOC; standard of care; SVR; sustained virologic response; BMI; b