Interleukin 28B genotype determination using DNA from different sources: A simple and reliable tool for the epidemiological and clinical characterization of hepatitis C

► IL28B genotype is related to spontaneous or treatment-induced HCV clearance. ► A real-time PCR method for IL28B genotyping was developed using small DNA quantities. ► DNA from invasive and non-invasive, fresh and archival samples could be genotyped. ► IL28B genotype prevalence was consistent with data from Caucasian populations.