Keywords: ILK، کیناز وابسته به یکپارین; HA, hyaluronic acid; ECM, extracellular matrix; HNF4α, hepatocyte nuclear factor 4; FAK, focal adhesion kinase; ILK, integrin-linked kinase; CDC42, cell division control protein 42; Rac1, Ras-related C3 botulinum toxin substrate; RhoA, Ras homolog family
مقالات ISI ILK، کیناز وابسته به یکپارین (ترجمه نشده)
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Signaling via PINCH: Functions, binding partners and implications in human diseases
Keywords: ILK، کیناز وابسته به یکپارین; PINCH, particularly interesting new cysteine-histidine-rich protein; EMT, epithelial-to-mesenchymal transition; ECM, extracellular matrix; IPP, ILK-PINCH-parvin; FA, focal adhesion; ILK, integrin-linked kinase; EGFR, epidermal growth factor receptor; PDGF
Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6–Abundant Breast Cancer Cells by Regulating γ-Secretase–Mediated Notch1 Activation in Caveolae 12
Keywords: ILK، کیناز وابسته به یکپارین; CSC, cancer stem cell; DAPI, 4',6-diamidino-2-phenylindole; DAPT, N-[N-(3,5-difluorophenacetyl)-l-alanyl]-S-phenylglycine t-butyl ester; GSK3β, glycogen synthase kinase 3β; IL-6, interleukin-6; ILK, integrin-linked kinase; NCT, nicastrin; NICD, Notch intr
CD99 inhibits CD98-mediated β1 integrin signaling through SHP2-mediated FAK dephosphorylation
Keywords: ILK، کیناز وابسته به یکپارین; SHP2, Src homology region 2 domain-containing phosphatase-2; FAK, focal adhesion kinase; PKC, protein kinase C; ILK, integrin-linked kinase; IPP, ILK–PINCH–parvin; Akt1, protein kinase B; FA, focal adhesions; SCLC, small cell lung-cancer cell line; LFA-1,
Inactivation of the Integrin-Linked Kinase (ILK) in osteoblasts increases mineralization
Keywords: ILK، کیناز وابسته به یکپارین; ILK, Integrin-Linked Kinase; αNAC, nascent polypeptide associated complex and coregulator alpha; GSK3β, glycogen synthase kinase 3β; col1A1, pro-α1(I) collagen; Bsp, Bone Sialoprotein; Ocn, Osteocalcin; ECM, extracellular matrix; DAPI, 4′,6-diamidino-2-ph
Interference with the contractile machinery of the fibroblastic chondrocyte cytoskeleton induces re-expression of the cartilage phenotype through involvement of PI3K, PKC and MAPKs
Keywords: ILK، کیناز وابسته به یکپارین; ERK, extracellular signaling regulated kinase; GAG, glycosaminoglycan; MEK, mitogen-activated protein kinase kinase; ILK, integrin-linked kinase; MAPK, mitogen-activated protein kinase; PI3K, phosphoinositide-3-kinase; PKC, protein kinase CStaurosporine;
The role of focal adhesion complexes in fibroblast mechanotransduction during scar formation
Keywords: ILK، کیناز وابسته به یکپارین; ECM, extracellular matrix; ERK, extracellular signal-regulated kinase; FAK, focal adhesion kinase; FPCL, fibroblast-populated collagen lattice; ILK, integrin-linked kinase; KO, knockout; MCP-1, monocyte chemoattractant protein-1; NPWT, negative pressure w
Integrins in mammary development
Keywords: ILK، کیناز وابسته به یکپارین; BLG, β-lactoglobulin; ECM, extracellular matrix; FAK, focal adhesion kinase; ILK, integrin-linked kinase; JAK2, Janus-activated kinase 2; JNK, Jun NH2-terminal kinase; MAPK, mitogen activated protein kinase; MMTV, mouse mammary tumor virus; P130Cas, p130
Detection of integrin-linked kinase in the serum of patients with malignant pleural mesothelioma
Keywords: ILK، کیناز وابسته به یکپارین; 10.1; 10.2; 14; 29BCD, benign chest disease; ILK, integrin-linked kinase; MCD, malignant chest disease other than malignant pleural mesothelioma; MPM, malignant pleural mesothelioma; SMRP, soluble mesothelin–related peptide
Akt signalling in health and disease
Keywords: ILK، کیناز وابسته به یکپارین; PDK-1, 3-phosphoinositide-dependent protein kinase 1; MAPKAP kinase 2, mitogen-activated protein kinase-activated protein kinase 2; ILK, integrin-linked kinase; PKC, protein kinase C; PIKK, PI3 kinase related kinase; mTORC, mammalian target of rapamycin c
Vinculin activates inside-out signaling of integrin αIIbβ3 in Chinese hamster ovary cells
Keywords: ILK، کیناز وابسته به یکپارین; CHO, Chinese hamster ovary; mAb, monoclonal antibody; APC, allophycocyanin; aa, amino acid; EGFP, enhanced green fluorescent protein; HIV, human immunodeficiency virus; sh, short hairpin; MOI, multiplicity of infection; ILK, integrin-linked kinase; PIP2,
Diabetes induces changes in ILK, PINCH and components of related pathways in the spinal cord of rats
Keywords: ILK، کیناز وابسته به یکپارین; DRG, dorsal root ganglia; fMRI, functional magnetic resonance imaging; GSK-3β, glycogen-synthase kinase 3β; ILK, integrin-linked kinase; MAP2, microtubule-associated protein 2; PINCH, Particularly Interesting New Cystine–Histine rich protein; PI3K, phosph
Bidirectional extracellular matrix signaling during tissue morphogenesis
Keywords: ILK، کیناز وابسته به یکپارین; CDK, cyclin-dependent kinase; ECM, extracellular matrix; EMT, epithelial–mesenchymal transition; ERK, extracellular signal-regulated kinase; FAK, focal adhesion kinase; ILK, integrin-linked kinase; PI3K, phosphatidylinositol 3′ kinase; JNK, Jun-N-terminal
Function of Akt/PKB signaling to cell motility, invasion and the tumor stroma in cancer
Keywords: ILK، کیناز وابسته به یکپارین; DNA-PK, DNA-dependent protein kinase; ECM, extracellular matrix; EMT, epithelial to mesenchymal transition; FOXO, Forkhead transcription factors; IGF-1, insulin-like growth factor-1; ILK, integrin-linked kinase; MMP, matrix metalloproteinase; mTOR, mammal
Overexpression of DLC-1 induces cell apoptosis and proliferation inhibition in the renal cell carcinoma
Keywords: ILK، کیناز وابسته به یکپارین; DLC-1, the deleted in liver cancer; RCC, renal cell carcinoma; ILK, integrin-linked kinase; FAK, focal adhesion kinase; pFAK, phospho FAK; CdkIs, cdk inhibitorsDLC-1; RCC; Apoptosis; Cell cycle; Migration
The developmentally-regulated Smoc2 gene is repressed by aryl-hydrocarbon receptor (Ahr) signaling
Keywords: ILK، کیناز وابسته به یکپارین; SPARC, secreted protein acidic and rich in cysteine; Smoc2, SPARC-related modular calcium binding protein-2; ILK, integrin-linked kinase; Ahr, aryl-hydrocarbon receptor; B[a]P, benzo[a]pyrene; TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin; PAH, polycyclic aro
The role of MMP-9 in integrin-mediated hippocampal cell death after pilocarpine-induced status epilepticus
Keywords: ILK، کیناز وابسته به یکپارین; ILK, integrin-linked kinase; MMPs, matrix metalloproteinases; SE, status epilepticusMatrix metalloproteinase; Integrins; Pilocarpine; Status epilepticus
Regulation of fibronectin matrix assembly and capillary morphogenesis in endothelial cells by Rho family GTPases
Keywords: ILK، کیناز وابسته به یکپارین; F-actin, filamentous actin; BAEC, bovine aortic endothelial cells; GTPases, guanine trinucleotide phosphatases; ILK, integrin-linked kinase; siRNA, small interfering RNA; ROCK, Rho-associated kinase; MLC, myosin light chain; MLCK, myosin light chain kinas
Affixin activates Rac1 via βPIX in C2C12 myoblast
Keywords: ILK، کیناز وابسته به یکپارین; ILK, integrin-linked kinase; PIX, PAK-interactive exchange factor; C2C12-affixin, stable C2C12 cell line expressing T7-tagged human affixin; GEF, guanine nucleotide exchange factor; GST, gulutathione S-transferase; CH, caponin-homology; DH, Dbl-homology;
Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin–ECM adhesion complex
Keywords: ILK، کیناز وابسته به یکپارین; ECM, extracellular matrix; ILK, integrin-linked kinase; MLP, muscle LIM protein; MTJ, myotendinous junctionMyotendinous junctions; ILK; Integrin; Laminin; loc; Zebrafish; Muscular dystrophy; MLP; β-parvin
Use of functional highly purified human platelets for the identification of new proteins of the IPP signaling pathway
Keywords: ILK، کیناز وابسته به یکپارین; FACS, fluorescence activated cell sorting; HLA-DQβ, human leukocyte antigen-DQβ; ILK, integrin-linked kinase; ISTH, International Society on Thrombosis and Haemostasis; MS, mass spectrometry; P2Y12, P2Y purinoceptor 12; PINCH, particularly interesting new
β-Catenin/Tcf-4 Inhibition After Progastrin Targeting Reduces Growth and Drives Differentiation of Intestinal Tumors
Keywords: ILK، کیناز وابسته به یکپارین; APC, adenomatous polyposis coli; CRC, colorectal cancer; GAST, human gastrin gene; Gast, murine gastrin gene; ICAT, inhibitor of β-catenin and Tcf-4; ILK, integrin-linked kinase; PI3k, phosphatidylinositol 3-kinase; RIA, radioimmuno-assay; shRNA, short ha
Differential involvement of the integrin-linked kinase (ILK) in RhoA-dependent rearrangement of F-actin fibers and induction of connective tissue growth factor (CTGF)
Keywords: ILK، کیناز وابسته به یکپارین; CTGF, connective tissue growth factor; ILK, integrin-linked kinase; LPA, lysophosphatidic acid; ROCK, Rho-associated kinase; SMA, smooth muscle actin; TGFbeta, transforming growth factor betaActin cytoskeleton; Colchicine; Connective tissue growth factor;
Integrin-mediated cell–matrix interactions for prosurvival and antiapoptotic signaling after genotoxic injury
Keywords: ILK، کیناز وابسته به یکپارین; Integrins; ECM; Tumor cells; CAM-RR; Genotoxic injuryECM, extracellular matrix; PI3K, phosphatidylinositol-3-kinase; ILK, integrin-linked kinase; FAK, focal adhesion kinase; CAM-RR, cell adhesion-mediated radioresistance; CAM-DR, cell adhesion-mediated dr