Keywords: ایمونو پروتئازوم; Proteasome; Immunoproteasome; 5-Arylidene-2-thioxoimidazolidin-4-ones; Non-covalent inhibitors; Docking studies;
مقالات ISI ایمونو پروتئازوم (ترجمه نشده)
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Keywords: ایمونو پروتئازوم; Porcine alveolar macrophages; RNA sequencing; Interferon gamma; Lipopolysaccharide; Immunoproteasome; Host restriction factor;
Keywords: ایمونو پروتئازوم; chronic rejection; immunoproteasome; kidney transplantation;
Keywords: ایمونو پروتئازوم; nPM / PM0.2; Nano-Scale Particulate Matter / Particulate Matter <â¯0.2â¯Âµm diameter; PM2.5; Particulate Matter <â¯2.5â¯Âµm diameter; Nrf2; Nuclear factor (erythroid-derived 2)-like 2; Bach1; BTB Domain And CNC Homolog 1; c-Myc; MYC proto-oncogene; TR
Keywords: ایمونو پروتئازوم; BTZ; bortezomib; CFZ; carfilzomib; C-L; caspase-like; CNS; central nervous system; CT-L; chymotrypsin-like; CYPs; cytochrome P450 enzymes; iP; immunoproteasome; IXZ; ixazomib; MM; multiple myeloma; OPZ; oprozomib; PD; pharmacodynamic; PI; proteasome inhib
Keywords: ایمونو پروتئازوم; Proteasome inhibitors; Immunoproteasome; Constitutive proteasome; 3-HydroxyOxindolylalanine derivatives; Tryptophan oxidation;
Keywords: ایمونو پروتئازوم; AE; Adverse event; BIPN; Bortezomib-induced peripheral neuropathy; C-L; Caspase-like; CFZ; Carfilzomib; ChT-L; Chymotrypsin-like action; IRd; Ixazomib, lenalidomide, and dexamethasone; LG; Leaving group; MM; Multiple myeloma; MTD; Maximum tolerated dose;
Keywords: ایمونو پروتئازوم; Immunoproteasome; hemorrhagic transformation; cerebral infarction; risk factors;
Keywords: ایمونو پروتئازوم; Bisbenzimidazole derivatives; Specific inhibitors of the trypsin-like sites; Constitutive proteasome; Immunoproteasome; In silico docking; c20S; 20S constitutive proteasome catalytic core; cChT-L (β5c subunit); chymotrypsin-like; cT-L (β2c subunit); try
Keywords: ایمونو پروتئازوم; Proteasome; Immunoproteasome; Proteolysis; Proteasome inhibitors; Domestic animals; Proteasome peptidase activities
Keywords: ایمونو پروتئازوم; mTOR; mammalian target of rapamycin; NF-κB; nuclear factor κ B; Stat1/3; signal transducer and activator of transcription 1/3; UPS; ubiquitin proteasome system; LMP; low molecular mass protein; Proteasome; mTOR; Heart; Rapamycin; Immunoproteasome; Infla
Keywords: ایمونو پروتئازوم; DOX; doxorubicin; ROS; reactive oxygen species; UPS; ubiquitin-proteasome system; E1s; ubiquitin activating enzymes; E2s; ubiquitin conjugating enzymes; E3s; ubiquitin ligases; DUBs; deubiquitinases; Cardiotoxicity; Doxorubicin; Apoptosis; Ubiquitin-prote
Keywords: ایمونو پروتئازوم; Immunoproteasome; Selective inhibitor; Non-peptide scaffold; Inhibitor identification;
Keywords: ایمونو پروتئازوم; Aging; Human liver; Standard proteasome; Immunoproteasome; PA28αβ regulator; Gender;
Keywords: ایمونو پروتئازوم; AhR; aryl hydrocarbon receptor; BaP; benzo(a)pyrene; BPDE; benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide; BW; body weight; FDR; false discovery rate; GO; Gene Ontology; GSH; glutathione; MHC; major histocompatibility complex; NKT; natural killer T cells; PA
Piperlongumine and some of its analogs inhibit selectively the human immunoproteasome over the constitutive proteasome
Keywords: ایمونو پروتئازوم; Piperlogumine; Piperlongumine analogs; Proteasome; Immunoproteasome;
Anti-viral immune response in the lung and thymus: Molecular characterization and expression analysis of immunoproteasome subunits LMP2, LMP7 and MECL-1 in pigs
Keywords: ایمونو پروتئازوم; Pig; Thymus; Immunoproteasome; LMP2; LMP7; MECL-1;
Induction of the Immunoproteasome Subunit Lmp7 Links Proteostasis and Immunity in α-Synuclein Aggregation Disorders
Keywords: ایمونو پروتئازوم; Neurodegeneration; Parkinson's disease; Dopaminergic neurons; Immunoproteasome; Proteostasis;
Inhibition of immunoproteasome promotes angiogenesis via enhancing hypoxia-inducible factor-1α abundance in rats following focal cerebral ischaemia
Keywords: ایمونو پروتئازوم; Immunoproteasome; Angiogenesis; Hypoxia-inducible factor-1a; Ischemic stroke;
Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism
Keywords: ایمونو پروتئازوم; TLR7; GS-9620; Hepatitis B virus; Interferon-alpha; cccDNA; Interferon-stimulated gene; MHC; Immunoproteasome; APOBEC; Smc5/6;
A comparative analysis between proteasome and immunoproteasome inhibition in cellular and humoral alloimmunity
Keywords: ایمونو پروتئازوم; Proteasome; Immunoproteasome; Cellular alloimmunity; Humoral alloimmunity; Transplantation;
Immunoproteasome subunit deficiency has no influence on the canonical pathway of NF-κB activation
Keywords: ایمونو پروتئازوم; NF-κB; Immunoproteasome; LMP2; LMP7; Inflammation;
ONX-0914, a selective inhibitor of immunoproteasome, ameliorates experimental autoimmune myasthenia gravis by modulating humoral response
Keywords: ایمونو پروتئازوم; EAMG; experimental autoimmune myasthenia gravis; MG; myasthenia gravis; LMP7; low-molecular mass polypeptide-7; Tfh; follicular helper T cells; MNC; mononuclear cell; ONX-0914; Immunoproteasome; Experimental autoimmune myasthenia gravis; Humoral immunity;
Interferon-dependent immunoproteasome activity during mouse adenovirus type 1 infection
Keywords: ایمونو پروتئازوم; Adenovirus; Immunoproteasome; Interferon gamma; Myocarditis; Respiratory infection; Inflammation;
Degradation of oxidized proteins by the proteasome: Distinguishing between the 20S, 26S, and immunoproteasome proteolytic pathways
Keywords: ایمونو پروتئازوم; Proteolysis; Proteasome; Immunoproteasome; Oxidative Stress; Adaptation; Nrf2
Modified siRNA effectively silence inducible immunoproteasome subunits in NSO cells
Keywords: ایمونو پروتئازوم; siRNA; Immunoproteasome; Chemical modifications; NSO cells;
Inhibition of the Immunoproteasome Subunit LMP7 with ONX 0914 Ameliorates Graft-versus-Host Disease in an MHC-Matched Minor Histocompatibility Antigen–Disparate Murine Model
Keywords: ایمونو پروتئازوم; Immunoproteasome; GVHD; Murine models; BMT
Enhanced rate of degradation of basic proteins by 26S immunoproteasomes
Keywords: ایمونو پروتئازوم; Proteasome; Immunoproteasome; Histones; MBP; Proteolysis; Trypsin-like activity;
The proteasome and the degradation of oxidized proteins: Part II – protein oxidation and proteasomal degradation
Keywords: ایمونو پروتئازوم; 20S Proteasome; Protein oxidation; Immunoproteasome; Protein aggregates
Anti-leukemic activity and mechanisms underlying resistance to the novel immunoproteasome inhibitor PR-924
Keywords: ایمونو پروتئازوم; Leukemia; Proteasome; Immunoproteasome; Proteasome inhibitor; PR-924
ReviewOxidation matters: The ubiquitin proteasome system connects innate immune mechanisms with MHC class I antigen presentation
Keywords: ایمونو پروتئازوم; Antigen presentation; MHC class I; Virus infection; Oxidative stress; Immunoproteasome;
Anti-viral immune responses in a primitive lung: Characterization and expression analysis of interferon-inducible immunoproteasome subunits LMP2, LMP7 and MECL-1 in a sarcopterygian fish, the Nigerian spotted lungfish (Protopterus dolloi)
Keywords: ایمونو پروتئازوم; Lungfish; Lung; Immunoproteasome; LMP2; LMP7; MECL-1;
The immunoproteasome β5i subunit is a key contributor to ictogenesis in a rat model of chronic epilepsy
Keywords: ایمونو پروتئازوم; 4-AP; 4-aminopyridine; Ach; acetylcholine; ACSF; artificial cerebrospinal fluid; CNS; central nervous system; i-proteasome; immunoproteasome; HMGB1; High Mobility Group Box-1; LPS; lipopolysaccharide; MCA; 7-amino-4-methylcoumarin; s-proteasome; standard
Purification and separation of the 20S immunoproteasome from the constitutive proteasome and identification of the subunits by LC–MS
Keywords: ایمونو پروتئازوم; Constitutive proteasome; Immunoproteasome; Proteasome purification; Proteasome characterization; Liquid Chromatography–Mass Spectrometry (LC–MS)
A bright approach to the immunoproteasome: Development of LMP2/β1i-specific imaging probes
Keywords: ایمونو پروتئازوم; Immunoproteasome; Fluorescent probes; Near-infrared fluorescent probe; LMP2;
Rare hereditary autoinflammatory disorders: Towards an understanding of critical in vivo inflammatory pathways
Keywords: ایمونو پروتئازوم; Hereditary autoinflammatory syndromes; NLRP3 inflammasome; Receptor antagonist; Immunoproteasome; Nakajo-Nishimura syndrome
Differential roles of proteasome and immunoproteasome regulators Pa28αβ, Pa28γ and Pa200 in the degradation of oxidized proteins
Keywords: ایمونو پروتئازوم; Oxidative stress adaptation (hormesis); Ubiquitin–proteasome system; Protein degradation; Proteasome regulators; Pa28 (11S) regulator; Immunoproteasome
Increased expression of FAT10 in colon benign, premalignant and malignant epithelial neoplasms
Keywords: ایمونو پروتئازوم; FAT10; Immunoproteasome; Toll-like receptors; Interferon; Proinflammatory response
The immunoproteasome in steatohepatitis: Its role in Mallory–Denk body formation
Keywords: ایمونو پروتئازوم; Mallory–Denk bodies (MDB); Immunoproteasome; FAT10; LMP2; LMP7; MECL-1; Mitochondria
The role of innate immunity in the pathogenesis of preneoplasia in drug-induced chronic hepatitis based on a mouse model
Keywords: ایمونو پروتئازوم; DDC, diethyl-1,4-dihydro-2,4,6-trimethyl-3,5-pyridinecarboxylate; MDBs, Mallory–Denk bodies; UbD, ubiquitin D in mice, FAT10 in man; ISRE, interferon stimulated response elementMallory–Denk bodies; Ubiquitin D; 26S proteasome; Immunoproteasome; Toll-like
Adenovirus E1A interacts directly with, and regulates the level of expression of, the immunoproteasome component MECL1
Keywords: ایمونو پروتئازوم; Adenovirus E1A; Immunoproteasome; MECL1
Evolutionary conserved pro-inflammatory and antigen presentation functions of zebrafish IFNγ revealed by transcriptomic and functional analysis
Keywords: ایمونو پروتئازوم; B2M; β-2-microglobulin; COX-2; cyclooxygenase-2; dpf; days post-fertilization; dpi; days post-injection; EPC; epithelioma papulosum cyprinid; hpi; hours post-injection; HSCs; hematopoietic stem cells; ISGs; IFN-stimulated genes; IRF; IFN regulatory facto
SAMe prevents the up regulation of toll-like receptor signaling in Mallory–Denk body forming hepatocytes
Keywords: ایمونو پروتئازوم; TLR, Toll-like receptors; UbD, ubiquitin D (FAT10); SAMe, S-adenosylmethionine; DDC, diethyl-1-4-dihydro-2, 4, 6-trimethyl-3,5-pyridine-decarboxylateTLRs; 26S proteasome; Immunoproteasome; Interferon γ; Proinflammatory cytokines
Interleukin-6 induces proinflammatory signaling in Schwann cells: A high-throughput analysis
Keywords: ایمونو پروتئازوم; Interleukin-6; Microarray; Immunoproteasome; Schwann cells; Nerve injury; Wallerian degeneration; Regeneration;
Upregulation of the immunoproteasome in peripheral blood mononuclear cells of patients with IgA nephropathy
Keywords: ایمونو پروتئازوم; IgA nephropathy; proteasome; immunoproteasome; transcription factors; NF-κB; proteinuria
Identification of O-glycosylated decapeptides within the MUC1 repeat domain as potential MHC class I (A2) binding epitopes
Keywords: ایمونو پروتئازوم; ESI-MS/MS; electrospray tandem mass spectrometry; HPLC; high-pressure liquid chromatography; MALDI-MS; matrix-assisted laser desorption mass spectrometry; VNTR; variable number of tandem repeats; Cancer vaccine; MHC class I; MUC1; Immunoproteasome; Cathep
Transformation of the proteasome with age-related macular degeneration
Keywords: ایمونو پروتئازوم; 20S Proteasome; Chymotrypsin-like activity; Immunoproteasome; Age-related macular degeneration
Differential intra-proteasome interactions involving standard and immunosubunits
Keywords: ایمونو پروتئازوم; Proteasome; Immunoproteasome; Proteasome assembly; Propeptide; Protein-protein interaction; Yeast two-hybrid interaction;
Myelin oligodendrocyte glycoprotein peptide-induced experimental allergic encephalomyelitis and T cell responses are unaffected by immunoproteasome deficiency
Keywords: ایمونو پروتئازوم; CD4+ T cell; CD8+ T cell; EAE; Immunoproteasome
Proteasome response to interferon-γ is altered in senescent human fibroblasts
Keywords: ایمونو پروتئازوم; AMC, 7-amido-4-methylcoumarin; CT-L, chymotrypsin-like; CPD, cumulative population doublings; IFN-γ, interferon-γ; PGPH, peptidyl-glutamyl peptide hydrolase; T-L, trypsin-likeHuman fibroblasts; Proteasome expression; Immunoproteasome; Replicative senescen