دانلود مقالات ISI درباره جذب روده + ترجمه فارسی

Sodium caseinate stabilized emulsions as a delivery system for epigallocatechin-gallate: Bioaccessibility, anti-proliferative activity and intestinal absorption

Keywords: جذب روده; Tea polyphenols; Sodium caseinate emulsions; Bioaccessibility; Intestinal absorption;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Behavior of three hypocholesterolemic peptides from soy protein in an intestinal model based on differentiated Caco-2 cell

Keywords: جذب روده; Hypocholesterolemic peptides; Caco-2 cells; DPP-IV; HMGCoAR; In silico docking; Intestinal absorption; LC-MRM; Mass spectrometry; Soy protein; ACN; acetonitrile; AP; apical; BL; basolateral; CV; coefficient of variance; DMEM; Dulbecco's Modified Eagle M

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

5-Fluororacil-Induced Gastrointestinal Damage Impairs the Absorption and Anticoagulant Effects of Dabigatran Etexilate

Keywords: جذب روده; bioavailability; cancer chemotherapy; gastrointestinal; intestinal absorption; P-glycoprotein; pharmacokinetics/pharmacodynamics;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Functionalization of nanodiamond with vitamin E TPGS to facilitate oral absorption of curcumin

Keywords: جذب روده; Nanodiamond; Curcumin; TPGS; Intestinal absorption; Oral bioavailability;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Ex-vivo absorption study of lysine R-lipoate salt, a new pharmaceutical form of R-ALA

Keywords: جذب روده; Everted sac; R-lipoic acid; Lysine R-lipoate salt; Intestinal absorption; Transepithelial transport;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Mechanistic Physiologically Based Pharmacokinetic Modeling of the Dissolution and Food Effect of a Biopharmaceutics Classification System IV Compound-The Venetoclax Story

Keywords: جذب روده; amorphous; absorption, distribution, metabolism, and excretion (ADME); bioavailability; food effect; physiologically based pharmacokinetic modeling; clinical pharmacokinetics; intestinal absorption; passive diffusion/transport; drug interaction; ASD; Amor

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Determination of intestinal permeability using in situ perfusion model in rats: Challenges and advantages to BCS classification applied to digoxin

Keywords: جذب روده; Intestinal absorption; In situ perfusion; Digoxin; Permeability; Biopharmaceutic Classification System;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Preparation and comparison of tacrolimus-loaded solid dispersion and self-microemulsifying drug delivery system by in vitro/in vivo evaluation

Keywords: جذب روده; Tacrolimus; Solid dispersion; Self-microemulsifying drug delivery system; Intestinal absorption;

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Organic anion-transporting polypeptide (OATP) 2B1 contributes to the cellular uptake of theaflavin

Keywords: جذب روده; Drug-food interaction; Intestinal absorption; Organic anion-transporting polypeptide (OATP) 2B1; Polyphenol; Theaflavin;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Uptake of perfluorooctanoic acid by Caco-2 cells: Involvement of organic anion transporting polypeptides

Keywords: جذب روده; Perfluorooctanoic acid (PFOA); Intestinal absorption; Organic anion transport polypeptide (OATP); Caco-2 cells;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Insulin stimulates transport of organic anion compounds mediated by organic anion transporting polypeptide 2B1 in the human intestinal cell line Caco-2

Keywords: جذب روده; OATP2B1; Insulin; Intestinal absorption; Caco-2 cell; Estrone-3-sulfate;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Chamomile (Matricaria recutita L.) decoction extract inhibits in vitro intestinal glucose absorption and attenuates high fat diet-induced lipotoxicity and oxidative stress

Keywords: جذب روده; Intestinal absorption; Ussing chamber; Lipotoxicity oxidative stress; Free iron;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Understanding the Potential Interethnic Difference in Rosuvastatin Pharmacokinetics

Keywords: جذب روده; clinical pharmacokinetics; drug interactions; race; organic anion-transporting polypeptide transporters; ABC transporters; efflux pumps; hepatic transport; intestinal absorption;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperImmunomodulatory properties of 1,2-dihydro-4-hydroxy-2-oxo-1,8-naphthyridine-3-carboxamide derivative VL15

Keywords: جذب روده; Immunomodulation; Intestinal absorption; Blood-brain barrier diffusion; Cannabinoid CB2 receptor; 1,8-Naphthyridine-3-carboxamide derivative; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Potential of single cationic amino acid molecule “Arginine” for stimulating oral absorption of insulin

Keywords: جذب روده; Arginine; Cationic amino acid; Insulin; Intestinal absorption; Oligoarginine;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Structural characterization, in-vivo acute systemic toxicity assessment and in-vitro intestinal absorption properties of tilapia (Oreochromis niloticus) skin acid and pepsin solublilized type I collagen

Keywords: جذب روده; Type I collagens; Denaturation temperature; Ftir; Biocompatibility; Intestinal absorption; Microstructure;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Adaptations métaboliques et digestives des espèces hibernantes

Keywords: جذب روده; Hibernation; Jeûne; Réalimentation; Absorption intestinale; Hibernation; Fasting; Refeeding; Intestinal absorption;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Bioinspired butyrate-functionalized nanovehicles for targeted oral delivery of biomacromolecular drugs

Keywords: جذب روده; Oral drug delivery; Butyrate-functionalization; Ligand-receptor interaction; Intestinal absorption; Mucus penetration; Bioinspired;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Functionalized PLA-PEG nanoparticles targeting intestinal transporter PepT1 for oral delivery of acyclovir

Keywords: جذب روده; PepT1 transporter; Polymer nanoparticles; Nanoprecipitation; Dipeptide ligand; Intestinal absorption; Acyclovir;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Intestinal Drug Interactions Mediated by OATPs: A Systematic Review of Preclinical and Clinical Findings

Keywords: جذب روده; drug interaction; inhibition; transporter; organic anion-transporting polypeptide transporters; intestinal absorption; polymorphism; AUC; area under the plasma concentration-time curve; DDIs; drug-drug interactions; EMA; European Medicines Agency; FDA

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Microvillus-Specific Protein Tyrosine Phosphatase SAP-1 Plays a Role in Regulating the Intestinal Paracellular Transport of Macromolecules

Keywords: جذب روده; epithelial delivery/permeability; intestinal absorption; paracellular transport; tight junction; colon; ileum;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Rosuvastatin Pharmacokinetics in Asian and White Subjects Wild Type for Both OATP1B1 and BCRP Under Control and Inhibited Conditions

Keywords: جذب روده; clinical pharmacokinetics; drug interaction; race; organic anion-transporting polypeptide transporters; ABC transporters; efflux pumps; hepatic transport; intestinal absorption;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Small-Dosing Clinical Study: Pharmacokinetic, Pharmacogenomic (SLCO2B1 and ABCG2), and Interaction (Atorvastatin and Grapefruit Juice) Profiles of 5 Probes for OATP2B1 and BCRP

Keywords: جذب روده; drug interactions; intestinal absorption; pharmacokinetics; pharmacogenomics; organic anion-transporting polypeptide transporters; ABC transporters;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Prediction of drug intestinal absorption in human using the Ussing chamber system: A comparison of intestinal tissues from animals and humans

Keywords: جذب روده; Intestinal absorption; animal tissues; mini-Ussing chamber; prediction; transport index (TI);

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Functional Identification of Plasma Membrane Monoamine Transporter (PMAT/SLC29A4) as an Atenolol Transporter Sensitive to Flavonoids Contained in Apple Juice

Keywords: جذب روده; atenolol; flavonoid; fruit juice; intestinal absorption; OATP; organic anion-transporting polypeptide; OCT1; organic cation transporter 1; PMAT; plasma membrane monoamine transporter;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Intestinal absorption mechanisms of 2′-deoxy-2′-β-fluoro-4′-azidocytidine, a cytidine analog for AIDS treatment, and its interaction with P-glycoprotein, multidrug resistance-associated protein 2 and breast cancer resistance protein

Keywords: جذب روده; 2′-deoxy-2′-β-fluoro-4′-azidocytidine; Caco-2 cells; Everted rat intestine; Intestinal absorption; ATP-binding cassette drug transporters;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Screening of pharmacokinetic properties of fifty dihydropyrimidin(thi)one derivatives using a combo of in vitro and in silico assays

Keywords: جذب روده; Dihydropyrimidin(thi)ones; P-glycoprotein; PAMPA assay; Blood-brain barrier; Intestinal absorption; Pharmacokinetics;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Determinants of Intestinal Availability for P-glycoprotein Substrate Drugs Estimated by Extensive Simulation With Mathematical Absorption Models

Keywords: جذب روده; drug-drug interaction; P-glycoprotein; physiologically based pharmacokinetic model; modeling and simulation; intestinal absorption; substrate drug; CLh; hepatic clearance; CLr; renal clearance; CYP3A; cytochrome P450 3A; DDI; drug-drug interaction; EQ

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2017 سفارش ترجمه

Involvement of organic cation transporter 3 (Oct3/Slc22a3) in the bioavailability and pharmacokinetics of antidiabetic metformin in mice

Keywords: جذب روده; Metformin; OCT3; Transporter; Intestinal absorption; Bioavailability; Mouse; AUC; area under the plasma concentration-time curve; CL; clearance; Cmax; maximum concentration; OCT/Oct; organic cation transporter; SLC; solute carrier; tmax; time to maximum

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Breast Cancer Resistance Protein Abundance, but Not mRNA Expression, Correlates With Estrone-3-Sulfate Transport in Caco-2

Keywords: جذب روده; Caco-2 cells; proteomics; liquid chromatography; mass spectrometry; intestinal absorption; efflux pumps; ABC transporters; ABC; ATP-dependent binding cassette; BCRP; breast cancer resistance protein; BSA; bovine serum albumin; E-3-S; estrone-3-sulfate; HB

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Absorption and retention of free and milk protein-bound cyano- and hydroxocobalamins. An experimental study in rats

Keywords: جذب روده; Cobalamin; Vitamin B12; Hydroxocobalamin; Cyanocobalamin; Intestinal absorption; Rat; Transcobalamin; Cbl; cobalamin/vitamin B12; OHCbl; hydroxo-Cbl; CNCbl; cyano-Cbl; NS; non significant; TC; transcobalamin; bTC; bovine transcobalamin; rbTC; recombinant

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Trans-intestinal absorption rates differ between free amino acids during larval development in Atlantic herring (Clupea harengus)

Keywords: جذب روده; Digestive tract; Intestinal absorption; Free amino acids; Fish larvae; Alanine; Proline; Glutamic acid;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Mechanistic studies of the transport of peimine in the Caco-2 cell model

Keywords: جذب روده; Peimine; Intestinal absorption; Caco-2 cell monolayer; P-glycoprotein; Transport mechanism

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Utility of PBPK Absorption Modeling to Guide Modified Release Formulation Development of Gaboxadol, a Highly Soluble Compound With Region-Dependent Absorption

Keywords: جذب روده; in vitro/in vivo correlations (IVIVC); controlled release; preclinical pharmacokinetics; physiologically based pharmacokinetic modeling; site-specific absorption; bioavailability; intestinal absorption;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Enhanced ex vivo intestinal absorption of olmesartan medoxomil nanosuspension: Preparation by combinative technology

Keywords: جذب روده; OLM, olmesartan medoxomil; P407, Poloxamer 407; HPH, high pressure homogenization; PDI, polydispersity indexNanosuspension; Combination methods; Particle size; Intestinal absorption

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Supersaturation and Precipitation of Posaconazole Upon Entry in the Upper Small Intestine in Humans

Keywords: جذب روده; supersaturation; precipitation; oral drug delivery; intestinal absorption; clinical pharmacokinetics; gastrointestinal; absorption; formulation; biopharmaceutics classification system; oral absorption;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Bile Salt Micelles and Phospholipid Vesicles Present in Simulated and Human Intestinal Fluids: Structural Analysis by Flow Field-Flow Fractionation/Multiangle Laser Light Scattering

Keywords: جذب روده; drug transport; duodenum; intestinal absorption; intestinal secretion/transport; oral drug delivery; food effects; lipids; particle size; phospholipids;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Displacement of Drugs From Cyclodextrin Complexes by Bile Salts: A Suggestion of an Intestinal Drug-Solubilizing Capacity From an In Vitro Model

Keywords: جذب روده; mathematical model; solubilization; bile salts; cyclodextrin; calorimetry (ITC); complexation; micelle; intestinal absorption;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Gastrointestinal and Systemic Monitoring of Posaconazole in Humans After Fasted and Fed State Administration of a Solid Dispersion

Keywords: جذب روده; supersaturation; precipitation; intestinal absorption; clinical pharmacokinetics; gastrointestinal; absorption; biopharmaceutics classification system; oral absorption; solid dispersion; amorphous;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Single-Pass Intestinal Perfusion (SPIP) and prediction of fraction absorbed and permeability in humans: A study with antiretroviral drugs

Keywords: جذب روده; Intestinal absorption; Permeability; Drug transport; Paracellular transport; Passive diffusion/transport; Fraction absorbed;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Absorption-enhancing effects of gemini surfactant on the intestinal absorption of poorly absorbed hydrophilic drugs including peptide and protein drugs in rats

Keywords: جذب روده; Intestinal absorption; Absorption enhancer; Gemini surfactant; Poorly absorbed drug; Peptide drug; Calcitonin;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of Polyoxyethylene Alkyl Ethers on the Intestinal Transport and Absorption of Rhodamine 123: A P-glycoprotein Substrate by In Vitro and In Vivo Studies

Keywords: جذب روده; intestinal absorption; P-glycoprotein; rhodamine 123; polyoxyethylene alkyl ether; pharmaceutical excipient;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Biopharmaceutic Profiling of Salts to Improve Absorption of Poorly Soluble Basic Drugs

Keywords: جذب روده; intestinal absorption; salts; supersaturation; precipitation; dissolution; pharmacokinetics; bioavailability; solubility-limited absorption;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Glyceollin Effects on MRP2 and BCRP in Caco-2 Cells, and Implications for Metabolic and Transport Interactions

Keywords: جذب روده; active transport; drug interaction; efflux pumps; food effects; flavonoids; genistein; glyceollin; intestinal absorption; intestinal metabolism; phytoestrogen;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Application of a Human Intestinal Epithelial Cell Monolayer to the Prediction of Oral Drug Absorption in Humans as a Superior Alternative to the Caco-2 Cell Monolayer

Keywords: جذب روده; intestinal absorption; membrane conductance and resistance; paracellular transport; permeability; tight junction; transcellular transport; ABC transporters; cell culture; intestinal epithelia;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Enhanced Oral Delivery of Bisphosphonate by Novel Absorption Enhancers: Improvement of Intestinal Absorption of Alendronate by N-Acyl Amino Acids and N-Acyl Taurates and Their Absorption-Enhancing Mechanisms

Keywords: جذب روده; intestinal absorption; absorption enhancer; tight junction; Caco-2 cells; membrane transport;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

The Evaluation of In Vitro Drug Dissolution of Commercially Available Oral Dosage Forms for Itraconazole in Gastrointestinal Simulator With Biorelevant Media

Keywords: جذب روده; precipitation; supersaturation; Caco-2 cells; dissolution; formulation; gastrointestinal; in vitro/in vivo correlations; intestinal absorption; permeability; cyclodextrins; AUC; area under the curve; AUDC; area under the dissolved drug amount-time curve

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Constitutive Triglyceride Turnover into the Mesenteric Lymph Is Unable to Support Efficient Lymphatic Transport of a Biomimetic Triglyceride Prodrug

Keywords: جذب روده; lymphatic transport; prodrugs; lipids/lipoproteins; intestinal absorption; site-specific delivery; ADA; arachidonic acid; BPF; bile and pancreatic fluid; CM; chylomicron; DGAT; diacylglycerol acyltransferease; FA; fatty acid; G3P; glycerol-3-phosphate; LA

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of 2 Polyoxyethylene Alkyl Ethers on the Function of Intestinal P-glycoprotein and Their Inhibitory Mechanisms

Keywords: جذب روده; intestinal absorption; P-glycoprotein; polyoxyethylene alkyl ethers; membrane fluidity; ATPase activity;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Explication of Definitional Description and Empirical Use of Fraction of Orally Administered Drugs Absorbed From the Intestine (Fa) and Intestinal Availability (Fg): Effect of P-glycoprotein and CYP3A on Fa and Fg

Keywords: جذب روده; ABC transporters; intestinal absorption; intestinal metabolism; mathematical model; passive diffusion/transport;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه