Keywords: AM251; 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(1-piperidyl)pyrazo-le-3-carboxamide; BSA; bovine serum albumin; DAMGO; [d-Ala2, N-MePhe4, Gly-ol]-enkephalin; DIEA; diisopropylethylamine; DMF; dimethylformamide; EGTA; ethylene glycol-bis(2-amino
مقالات ISI (ترجمه نشده)
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Keywords: Synthetic cannabinoids; GC-MS; LC-MS/MS; Analysis; Review; AAls; Aminoalkylindoles; AAPCC; American Association of Poison Control Centres; AB-001; Adamantan-1-yl(1-pentyl-1H-indol-3-yl)methanone; AB-CHMINACA; N-[(1S)-1-(Aminocarbonyl)-2-methylpropyl]-1-(c
Keywords: Forensic toxicology; JWH-018; MAM-2201; UR-144; STS-135; 5F-AÐB-48;
Keywords: Synthetic cannabinoids; Prevalence; DUID; UPLC-MS/MS; AM-2201; JWH-018;
Keywords: Synthetic cannabinoids; Metabolism; Cunninghamella elegans; JWH-018; JWH-073; AM2201
Excretion of metabolites of the synthetic cannabinoid JWH-018 in urine after controlled inhalation
Keywords: Pharmacokinetics; Synthetic cannabinoids; JWH-018; Metabolism; Urine; Liquid chromatography-mass spectrometry;
Methodology for controlled administration of smoked synthetic cannabinoids JWH-018 and JWH-073
Keywords: Synthetic cannabinoids; Pharmacokinetics; Cannabis; JWH-018; JWH-073;
Novel behavioral assays of spontaneous and precipitated THC withdrawal in mice
Keywords: 2-AG; 2-arachidonoylglycerol; CB1; Cannabinoid receptor subtype 1; CB2; Cannabinoid receptor subtype 2; FAAH; Fatty acid amide hydrolase; JZL184; 4-nitrophenyl-4-[bis(1,3-benzodioxol-5-yl)(hydroxy)methyl]piperidine-1-carboxylate; JWH-018; Naphthalen-1-yl-
Effect fingerprinting of new psychoactive substances (NPS): What can we learn from in vitro data?
Keywords: 2C-B; 2,5-Dimethoxy-4-bromophenethylamine; 4-FA; 4-Fluoroamphetamine; 4-MEC; 4-Methylethcathinone; 4-MMC; 4-Methylmethcathinone, a.k.a. mephedrone; 5-APB; 5-(2-Aminopropyl)benzofuran; 6-APB; 6-(2-Aminopropyl)benzofuran; 5-HT; Serotonin; 25B-NBOMe; 4-Bromo
Pharmacokinetic properties of the synthetic cannabinoid JWH-018 and of its metabolites in serum after inhalation
Keywords: Pharmacokinetics; Synthetic cannabinoids; JWH-018; Metabolites; Liquid chromatography-mass spectrometry;
Toxicological impact of JWH-018 and its phase I metabolite N-(3-hydroxypentyl) on human cell lines
Keywords: Synthetic cannabinoids; JWH-018; JWH-018 N-(3-hydroxypentyl) metabolite; HEK293T; SH-SY5Y; Toxicity;
Evaluation of first generation synthetic cannabinoids on binding at non-cannabinoid receptors and in a battery of in vivo assays in mice
Keywords: Alkylindoles; Functional observation battery; JWH-018; Receptor binding; Synthetic cannabinoids;
Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence
Keywords: JWH-018; Novel object recognition; Hippocampus; LTP; GABA/glutamate release; AM251; 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide; CB1R; Cannabinoid receptor 1; JWH-018; 1-pentyl-3-(1-naphthoyl)indole; JWH-0
JWH-018 Ï-OH, a shared hydroxy metabolite of the two synthetic cannabinoids JWH-018 and AM-2201, undergoes oxidation by alcohol dehydrogenase and aldehyde dehydrogenase enzymes in vitro forming the carboxylic acid metabolite
Keywords: ADH; alcohol dehydrogenase; ALDH; aldehyde dehydrogenase; AO; aldehyde oxidase; Clint.micr; microsomal intrinsic clearance; CYP; cytochrome P450; EIC; extracted ion chromatogram; EMCDDA; European Monitoring Centre for Drugs and Drug Addiction; ESI; electr
Native CB1 receptor affinity, intrinsic activity and accumbens shell dopamine stimulant properties of third generation SPICE/K2 cannabinoids: BB-22, 5F-PB-22, 5F-AKB-48 and STS-135
Keywords: Cannabinoids; CB1 receptors; Dopamine; Microdialysis; Spice; K2; GTPγS binding; AM 251; 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(1-piperidyl)pyrazole-3-carboxamide; BB-22; 1-(cyclohexylmethyl)-1H-indole-3-carboxylic acid 8-quinolinyl ester; 5F
Validation of JWH-018 and its metabolites in blood and urine by UPLC–MS/MS: Monitoring in forensic cases
Keywords: Synthetic cannabinoid; JWH-018; Metabolite; LC–MS/MS
Study on the mass fragmentation pathway of the synthetic cannabinoids JWH-018 and JWH-073
Keywords: Mass fragmentation pathway; JWH-018; JWH-073; GC-MS/MS; GC-HRMS;
Novel halogenated derivates of JWH-018: Behavioral and binding studies in mice
Keywords: Î9-THC; JWH-018; JWH-018 Br; JWH-018 Cl; CB1 receptor; Synthetic cannabinoids; AM 251; 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide; JWH-018; 1-pentyl-3-(1-naphthoyl)indole; JWH-018Cl; (1-(5-chloro-pentyl)
Repeated administration of phytocannabinoid Î9-THC or synthetic cannabinoids JWH-018 and JWH-073 induces tolerance to hypothermia but not locomotor suppression in mice, and reduces CB1 receptor expression and function in a brain region-specific manner
Keywords: AM-2201; [1-(5-fluoropentyl)-1H-indol-3-yl]-1-naphthalenyl-methanone; CB1Rs; cannabinoid type 1 receptors; CP-47,497; rel-2-[(1S,3R)-3-hydroxycyclohexyl]-5-(2-methylnonan-2-yl)phenol; CP-55,940; 5-(1,1-dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclo
Cross-substitution of Î9-tetrahydrocannabinol and JWH-018 in drug discrimination in rats
Keywords: Discriminative stimulus; JWH-018; JWH-073; JWH-210; Synthetic cannabinoids; Î9-tetrahydrocannabinol;
Moving around the molecule: Relationship between chemical structure and in vivo activity of synthetic cannabinoids
Keywords: Alkylindoles; Aromatic stacking; Cannabinoids; Herbal marijuana; Indoles; JWH-018; Pyrroles; Review; Spice; Synthetic cannabinoids
Characterization of in vitro metabolites of JWH-018, JWH-073 and their 4-methyl derivatives, markers of the abuse of these synthetic cannabinoids
Keywords: Alkylindole metabolites; JWH-018; JWH-073; JWH-122 ;1-Butyl-3-(1-(4-methyl)naphthoyl)indole; GC/FID; GC/MS
Gas chromatography–mass spectrometry of JWH-018 metabolites in urine samples with direct comparison to analytical standards
Keywords: JWH-018; Metabolites; ‘K2’; Synthetic cannabinoid; GC–MS
Monitoring of urinary metabolites of JWH-018 and JWH-073 in legal cases
Keywords: Synthetic cannabinoid; JWH-018; JWH-073; Metabolite; LC–MS/MS
Identification, extraction and quantification of the synthetic cannabinoid JWH-018 from commercially available herbal marijuana alternatives
Keywords: Herbal marijuana alternative; Spice; Synthetic marijuana; JWH-018; DART–mass spectrometry; Accelerated solvent extraction
Identification of 1-butyl-3-(1-(4-methyl)naphtoyl)indole detected for the first time in “herbal high” products on the Italian market
Keywords: Cannabimimetic alkylindoles; JWH-018; JWH-073; 1-Butyl-3-(1-(4-methyl)naphthoyl)indole; Herbal products
Effects of synthetic cannabinoids on electroencephalogram power spectra in rats
Keywords: Electroencephalogram; Synthetic cannabinoids; Cannabicyclohexanol; CP-47,497; JWH-018; Locomotor activity
Detection and disposition of JWH-018 and JWH-073 in mice after exposure to “Magic Gold” smoke
Keywords: Cannabimimetics; JWH-018; JWH-073; Magic Gold; HPLC/MS/MS;
Inhalation exposure to smoke from synthetic “marijuana” produces potent cannabimimetic effects in mice
Keywords: JWH-018; Marijuana; Inhalation; Cannabinoid; Herbal incense products; Tetrad;
The impact of changes in UK classification of the synthetic cannabinoid receptor agonists in ‘Spice’
Keywords: Spice; Synthetic cannabinoids; Legislation; Cannabis; JWH-018
“Spice” Girls: Synthetic Cannabinoid Intoxication
Keywords: spice; cannabinoid; JWH-018; JWH-073
Synthetic cannabinoid JWH-018 and psychosis: An explorative study
Keywords: Cannabinoids; Psychoses, substance-induced; Designer drugs; Qualitative research; Psychotic disorders; Forensic psychiatry; Spice; JWH-018
Chromatography–mass spectrometry studies on the metabolism of synthetic cannabinoids JWH-018 and JWH-073, psychoactive components of smoking mixtures
Keywords: JWH-018; JWH-073; Herbal mixture; Metabolites; GC–MS; LC–MS
Sensitive and rapid quantification of the cannabinoid receptor agonist naphthalen-1-yl-(1-pentylindol-3-yl)methanone (JWH-018) in human serum by liquid chromatography–tandem mass spectrometry
Keywords: JWH-018; Naphthalen-1-yl-(1-pentylindol-3-yl)methanone; Spice; LC/MS/MS; ESI
Spice drugs as a new trend: Mode of action, identification and legislation
Keywords: Spice; Synthetic cannabinoids; JWH-018; HU-210; CP-47,497
Detection of JWH-018 metabolites in smoking mixture post-administration urine
Keywords: JWH-018; Synthetic cannabinoid; Metabolism; GC–MS; LC–MS
Chemical analysis of synthetic cannabinoids as designer drugs in herbal products
Keywords: Cannabicyclohexanol; JWH-018; Oleamide; CP-47,497; JWH-073; Synthetic cannabinoid
Spice: A never ending story?
Keywords: Spice; CP 47,497-C8; JWH-018; Cannabimimetic; Alkylaminoindole; GC–MS